Neocortical somatostatin neuron diversity in cognition and learning

Trends in Neurosciences, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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Topography of putative bi-directional interaction between hippocampal sharp-wave ripples and neocortical slow oscillations

Neuron, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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Topography of putative bidirectional interaction between hippocampal sharp wave ripples and neocortical slow oscillations

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 23, 2024

Summary Systems consolidation relies on coordination between hippocampal sharp-wave ripples (SWRs) and neocortical UP/DOWN states during sleep. However, whether this coupling exists across neocortex the mechanisms enabling it remain unknown. By combining electrophysiology in mouse hippocampus (HPC) retrosplenial cortex (RSC) with widefield imaging of dorsal neocortex, we found spatially temporally precise bidirectional hippocampo-neocortical interaction. HPC multi-unit activity SWR probability was correlated default mode network, highest modulation by RSC deep Further, some SWRs were preceded high rebound excitation accompanying DMN DOWN→UP transitions, while large-amplitude often followed DOWN originating RSC. We explain these electrophysiological results a model which are weakly coupled excitable systems capable bi-directional perturbation suggest may act as gateway through can perturb downstream cortical regions via cortico-cortical propagation states.

Language: Английский

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The claustrum and synchronized brain states

Trends in Neurosciences, Journal Year: 2024, Volume and Issue: 47(12), P. 1028 - 1040

Published: Nov. 2, 2024

Language: Английский

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