Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
15
Published: Dec. 16, 2024
There
is
growing
evidence
that
deficiencies
in
specific
nutrients
can
impact
testosterone
levels
older
men.
However,
research
examining
the
predictive
value
of
overall
nutritional
status
on
remains
limited.
The
Geriatric
Nutritional
Risk
Index
(GNRI)
an
effective
tool
for
assessing
elderly.
Therefore,
this
study
aimed
to
investigate
potential
correlation
between
GNRI
and
serum
total
(TT).
Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
15
Published: June 24, 2024
Purpose
To
evaluate
the
association
of
Life’s
Essential
8
(LE8)
and
its
subscales
with
male
biochemical
androgen
deficiency
(MBAD)
total
testosterone
based
on
data
from
national
health
nutrition
examination
survey
(NHANES)
database.
Methods
Data
males
aged
20
years
or
older
NHANES
2013–2016
were
extracted.
LE8
score
was
calculated
American
Heart
Association
definitions.
Total
(TT)
values
measured
in
using
precise
isotope
dilution
liquid
chromatography.
MBAD
defined
as
serum
TT
<300
ng/dL.
Univariate
multivariable
analyses
conducted.
Propensity
matching
(PSM)
weighted
regression
after
added
sensitivity
analyses.
The
generalized
additive
model,
smooth
curve
fitting,
recursive
algorithm
used
to
determine
potential
inflection
points.
Piecewise
models
log-likelihood
ratio
test
quantify
nonlinear
effects.
Results
A
3094
participants
who
above
included.
Out
them,
805
diagnosed
MBAD.
After
adjusting
confounders
independently
associated
(OR
0.96,
P
<
0.001)
(β
2.7,
0.001).
remained
robust
even
PSM.
non-linear
relationship
behaviors
revealed.
Conclusion
an
independent
protective
factor
a
feasible
approach
promote
endocrine
sexual
function.
Urology Herald,
Journal Year:
2025,
Volume and Issue:
12(6), P. 52 - 58
Published: Jan. 7, 2025
Healthy
sleep
is
essential
for
human
health.
It
performs
important
biological
functions
and
positively
affects
health
longevity
through
the
metabolic
endocrine
systems.
Sleep
disorders
are
serious
clinical
conditions
that
can
reduce
life
expectancy
quality
of
life.
deprivation,
circadian
rhythm
disruption,
obstructive
apnea
syndrome
widespread
in
modern
society
accumulate
over
time.
The
adverse
cardiometabolic
reproductive
consequences
insufficient
becoming
increasingly
evident.
In
men,
persistent
deprivation
lead
to
several
problems,
including
hypogonadism.
This
because
testosterone
levels
increase
during
peak
rapid
eye
movement
(REM)
sleep.
Consequently,
disruptions
architecture
loss
a
decrease
male
sex
hormone
levels.
On
other
hand,
low
worsen
efficiency
nighttime
awakenings.
article
reviews
discusses
relationship
between
disturbances
deficiency,
as
well
methods
correcting
these
conditions.
International Journal of Endocrinology,
Journal Year:
2025,
Volume and Issue:
2025(1)
Published: Jan. 1, 2025
Objective:
To
evaluate
the
association
between
sleep
duration
with
serum
estradiol
concentrations
and
its
variation
by
sex
age
in
American
adults.
Methods:
Data
were
analyzed
for
5406
men
women
(≥
20
years
old)
who
participated
cycles
of
National
Health
Nutrition
Examination
Survey
2013–2016,
a
cross‐sectional
study.
Total
(pg/mL)
was
measured
categorized
(low,
normal,
high)
based
on
NHANES
protocol.
Sleep
classified
as
≤
6,
6–9,
≥
9
h.
Weighted
multivariable
adjusted
multinomial
logistic
regression
models
conducted
to
assess
these
associations.
Results:
Our
analysis
revealed
no
significant
associations
among
both
women.
Specifically,
comparisons
durations
(≤
6
h)
reference
group
(6–9
across
various
categories
showed
odds
ratios
low
high
that
remained
statistically
nonsignificant
fully
models.
These
findings
suggest
that,
unlike
previous
studies
linking
variations
other
hormones,
do
not
appear
be
significantly
affected
differences
either
all
groups
studied.
Conclusion:
The
lack
indicates
may
influence
levels
general
population
results
underscore
importance
continued
research
into
how
influences
hormonal
balance.
However,
it
is
important
note
data
we
used
are
from
study,
which
cannot
establish
causal
relationship
estradiol.
Future
should
investigate
additional
factors,
such
genetic
predispositions,
lifestyle
habits,
environmental
influences,
modulate
hormone
levels.
Frontiers in Physiology,
Journal Year:
2025,
Volume and Issue:
16
Published: Feb. 21, 2025
The
atherogenic
index
of
plasma
(AIP),
defined
as
log10
(triglycerides/high-density
lipoprotein
cholesterol),
serves
a
biomarker
for
atherosclerosis
and
cardiovascular
disease
(CVD).
It
is
also
associated
with
conditions
such
type
2
diabetes,
insulin
resistance,
depression,
both
overall
mortality.
Serum
lipids
have
been
proven
to
influence
serum
testosterone
levels,
AIP
significant
marker
lipid
levels.
We
hypothesize
that
may
specific
relationship
testosterone.
This
article
aims
evaluate
the
correlation
between
total
(TT),
well
deficiency
(TD),
among
U.S.
population.
Data
were
collected
from
National
Health
Nutrition
Examination
Survey
(NHANES)
database
2011
2016.
study
was
categorized
into
four
groups
based
on
quartiles
AIP.
Weighted
multivariate
linear
regression
logistic
utilized
relationships
TT,
TD.
Restricted
cubic
spline
(RCS)
used
investigate
non-linear
association
TT
subgroup
analysis
method
employed
TD
across
various
stratifications.
Ultimately,
sensitivity
involved
comparison
weighted
unweighted
data
analyses
ascertain
stability
conclusions.
A
2,572
participants
included
in
final
study.
After
adjusting
all
confounding
factors,
showed
independently
negatively
(β
=
-93.42,
95%CI:
-123.66,
-63.18,
P
<
0.001),
level
higher
risk
(OR
3.45,
2.09,
5.69,
0.001).
In
quartile
AIP,
levels
decreased
most
-74.81,
-105.27,
-44.35,
p
0.001)
highest
2.89,
1.70,
4.93,
addition,
stratified
similar
results
subgroups
except
those
diabetes
(P
interaction
>0.05
comparisons).
revealed
elevated
-101.74,
-123.18,
-80.3,
increased
incidence
3.01,
2.17,
4.17,
data.
Increased
correlate
prevalence
Additional
research
necessary
underlying
mechanisms
connecting
them.
Sleep Medicine Reviews,
Journal Year:
2025,
Volume and Issue:
unknown, P. 102080 - 102080
Published: March 1, 2025
Infertility
affects
millions
of
couples
globally,
with
male
factors
contributing
up
to
50
%
cases.
Despite
the
existing
Assisted
Reproduction
Technologies
(ART),
decreased
sperm
quality
and
infertility
persist.
Evidence
suggests
that
sleep
is
crucial
for
normal
reproductive
function,
noticeable
increase
in
rates
aligns
growing
prevalence
deprivation,
suggesting
a
connection
between
both
conditions.
This
literature
review
explores
possible
links
disturbances,
special
emphasis
on
insomnia,
most
prevalent
disorder,
health.
It
delves
into
latest
findings
regarding
such
as
quality,
hormone
levels,
overall
function
from
studies
mammals,
rodents
humans.
Through
concise
synthesis
these
findings,
we
unveil
potential
mechanisms
provide
insights
clinicians
researchers
field
PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(5), P. e0322802 - e0322802
Published: May 8, 2025
Background
Obesity
poses
a
significant
global
health
burden.
This
study
aimed
to
investigate
the
prevalence
of
obesity
in
Mongolia
and
its
associations
with
autonomic
cognitive
functions
while
considering
potential
psychosocial
risk
factors.
Methods
population-based,
cross-sectional
included
382
participants
who
underwent
physical
examinations,
completed
health-related
questionnaires,
participated
heart
rate
variability
(HRV)
testing
for
assessment
mini-mental
state
examination
evaluation.
Results
was
28.1%
(age-sex
adjusted).
Individuals
were
more
likely
be
older,
married,
have
lower
education,
engage
less
activity.
They
exhibited
imbalance,
decreased
nervous
system
activity,
function,
sleep
disturbances
compared
individuals
without
obesity.
Body
mass
index,
waist
circumference
inversely
correlated
HRV
indices.
Female
sex,
apartment
living,
alcohol
consumption,
disturbances,
dysfunction
emerged
as
factors
Independent
predictors
systolic
blood
pressure,
neck
circumference,
age,
height,
apnea,
predicted
decline.
Furthermore,
generalized
linear
mediation
models
revealed
partial
effect
on
association
between
Conclusion
highlights
high
general
population
(28.1%)
identifies
distinct
characteristics
associated
condition.
our
findings
suggest
indirect
mediated
by
dysfunction.
Further
research
is
needed
elucidate
causal
relationships
develop
targeted
interventions
high-risk
groups
(females,
education)
promotion
initiatives
healthy
lifestyles
(less
alcohol,
exercise,
hygiene)
address
both
complications,
including
Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
15
Published: June 3, 2024
Background
Serum
testosterone
is
intrinsically
associated
to
cardiovascular
disease.
Our
aim
explore
the
relationship
between
recently
updated
health
measurement,
known
as
Life’s
Essential
8
(LE8),
and
prevalence
of
deficiency
(TD)
in
adult
males
United
States.
Methods
Study
data
was
obtained
from
National
Health
Nutrition
Examination
Survey
(NHANES)
2011
2016.
A
weighted
multivariate
logistic
regression
model
applied
evaluate
correlation
LE8
deficiency.
Restricted
Cubic
Spline
(RCS)
employed
its
non-linear
relationship.
In
addition,
a
stratified
analysis
conducted.
Results
The
final
included
2332
participants
NHANES
After
adjusting
for
confounding
factors,
odds
ratios
(ORs)
95%
confidence
intervals
(CIs)
with
moderate
higher
scores
compared
lowest
were
0.59
(0.38–0.92)
0.38
(0.19–0.76),
respectively.
results
subgroup
showed
that
score
significantly
TD
among
young
middle-aged
participants.
Conclusion
lower
related
incidence
deficiency,
especially
men.
Further
research
necessary
potential
mechanisms
them.
