Molecular Perspective of Dietary Influences on the Gut Microbiome alongside Neurological Health: Exploring the Gut-Brain Axis DOI

Zahra H. Almahal,

Anwarul Hasan, Shaikh A. Razzak

et al.

ACS Chemical Neuroscience, Journal Year: 2025, Volume and Issue: unknown

Published: May 5, 2025

Gut-brain axis, an intricate, two-way communication network between gut microorganisms and the central nervous system, plays a critical role in controlling brain function thereby influencing mental health. Changes to this frequently due shifts microbiota, can greatly affect by hindering creation of essential metabolites. This review examines new nutritional trends, including fermented foods diets rich prebiotics, that demonstrate potential improve microbial diversity metabolic well-being. Although current studies emphasize possible advantages, most concentrate mainly on older populations, leaving research younger groups limited. The field psychiatry encounters difficulties methodologies intricacies nutrient balance, potentially prompt interventions. highlights necessity for prolonged evaluate effects eating habits, especially regarding Western dietary patterns. Promising fields include influence Mediterranean diet, symbiotic short-chain fatty acids (SCFAs), importance high-fiber foods, polyphenols, fruits vegetables enhancing health through gut-derived We promote interdisciplinary methods combine nutrition science, microbiology, neurology create tailored recommendations focused

Language: Английский

Mediating Role of Blood Metabolites in the Relationship Between Arrhythmia and Hyperthyroidism in East Asian Populations DOI

X. Zhang,

Lei Lü,

A. Wang

et al.

Nutrition Metabolism and Cardiovascular Diseases, Journal Year: 2025, Volume and Issue: unknown, P. 103906 - 103906

Published: Feb. 1, 2025

Language: Английский

Citations

0
Machine learning study on predicting depressive symptoms and genetic correlations in Parkinson’s disease DOI Creative Commons
Haijun Zhang, Yifan Zhang, Guoqiang Li

et al.

Frontiers in Aging Neuroscience, Journal Year: 2025, Volume and Issue: 17

Published: April 9, 2025

Depressive symptoms are prevalent in individuals with Parkinson's disease. Previous research has demonstrated a significant association between the triglyceride glucose (TyG) index and depression. Leveraging multicenter clinical data, present study evaluates predictive capacity of TyG for depressive PD patients, aiming to establish its potential role identifying at risk A comparative analysis multiple machine learning models was conducted predict depression ultimately selecting most effective model. Key variables, including diabetes status, sex, cholesterol levels, triglycerides, blood glucose, sleep disturbances, were incorporated into support vector (SVM)-based nomogram assess patients. Additionally, genome-wide (GWAS) utilizing external databases confirmed causal relationship Furthermore, this explores biological functions molecular mechanisms underlying shared transcriptomic proteins depression, providing insights pathophysiological links two conditions.

Language: Английский

Citations

0
Molecular Perspective of Dietary Influences on the Gut Microbiome alongside Neurological Health: Exploring the Gut-Brain Axis DOI

Zahra H. Almahal,

Anwarul Hasan, Shaikh A. Razzak

et al.

ACS Chemical Neuroscience, Journal Year: 2025, Volume and Issue: unknown

Published: May 5, 2025

Gut-brain axis, an intricate, two-way communication network between gut microorganisms and the central nervous system, plays a critical role in controlling brain function thereby influencing mental health. Changes to this frequently due shifts microbiota, can greatly affect by hindering creation of essential metabolites. This review examines new nutritional trends, including fermented foods diets rich prebiotics, that demonstrate potential improve microbial diversity metabolic well-being. Although current studies emphasize possible advantages, most concentrate mainly on older populations, leaving research younger groups limited. The field psychiatry encounters difficulties methodologies intricacies nutrient balance, potentially prompt interventions. highlights necessity for prolonged evaluate effects eating habits, especially regarding Western dietary patterns. Promising fields include influence Mediterranean diet, symbiotic short-chain fatty acids (SCFAs), importance high-fiber foods, polyphenols, fruits vegetables enhancing health through gut-derived We promote interdisciplinary methods combine nutrition science, microbiology, neurology create tailored recommendations focused

Language: Английский

Citations

0