Prevalence, virulence factors and antifungal susceptibility of oral isolates of Candida albicans from patients with cystic fibrosis in Mexico DOI
Ana L. Ríos‐López,

María Fernanda Garza-Velásquez,

Gloria M. González

et al.

Revista Iberoamericana de Micología, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Host immune response against fungal biofilms DOI Creative Commons
Mohammad Abdul Mannan, Sunna Nabeela,

Reetakshi Mishra

et al.

Current Opinion in Microbiology, Journal Year: 2024, Volume and Issue: 81, P. 102520 - 102520

Published: Aug. 9, 2024

Fungal biofilms are a multilayered community of cells attached to mucosal or abiotic surfaces enclosed in coating self-produced extracellular polymeric matrix. The sheer density protected by shield not only makes the biofilm impermeable antimicrobials immune but also hidden from host recognition. Biofilms serve as reservoir drug-resistant persister and dispersal armored with virulence factors adept at evading system. Here, we summarize latest knowledge on immunomodulatory properties formed Candida species other biofilm-forming fungal pathogens such Aspergillus Cryptococcus. Finally, deliberate promising strategies help activate system for combating biofilms.

Language: Английский

Citations

4
Promising Applications of Jaboticaba Berry in the Industry: Cosmetics and Pharmaceuticals DOI

Luiz Lira Soares,

Daniele Daiane Affonso,

Ana Lúcia Tasca Góis Ruiz

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Bioinorganic Chemistry Meets Microbiology: Copper(II) and Zinc(II) Complexes Doing the Cha-Cha with the C-t-CCL-28 Peptide, Dancing till the End of Microbes DOI Creative Commons

Klaudia Szarszoń,

Natalia Baran,

Paulina Śliwka

et al.

Inorganic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

The necessity to move away from conventional antibiotic therapy has sparked interest in antimicrobial peptides (AMPs). One fascinating example is human CCL-28 chemokine produced by acinar epithelial cells the salivary glands. It can also be released into oral cavity with saliva, playing a crucial role protection. C-terminal domain of possesses antifungal and antibacterial properties, which are likely linked membrane disruption enzyme leakage. Studies suggest that AMPs become more potent after they have bound Cu(II) or Zn(II). In many cases, these ions essential for maximizing effectiveness altering peptides' physicochemical such as their local charge structure. examined peptide binds Zn(II) very effectively, forming equimolar complexes. Metal ion binding affinity, coordination mode, activity strongly depend on pH environment. Coordination modes been proposed based results potentiometric titrations, spectroscopic studies (UV-visible, electron paramagnetic resonance circular dichroism at different path lengths), mass spectrometry. properties complexes fragment assessed against fungal bacterial strains, demonstrating exceptional

Language: Английский

Citations

1
Anti-cancer activity of secreted aspartyl proteinase protein from Candida tropicalis on human cervical cancer HeLa cells DOI
Esmaeel Panahi Kokhdan,

Pouria Khodavandi,

Mohammad Hasan Ataeyan

et al.

Toxicon, Journal Year: 2024, Volume and Issue: 249, P. 108073 - 108073

Published: Aug. 15, 2024

Language: Английский

Citations

0
APMIS focus issue 2024—The microenvironment in human disease DOI Open Access
Peter Østrup Jensen, Mads Lichtenberg

Apmis, Journal Year: 2024, Volume and Issue: 132(12), P. 903 - 905

Published: Nov. 8, 2024

Language: Английский

Citations

0
Prevalence, virulence factors and antifungal susceptibility of oral isolates of Candida albicans from patients with cystic fibrosis in Mexico DOI
Ana L. Ríos‐López,

María Fernanda Garza-Velásquez,

Gloria M. González

et al.

Revista Iberoamericana de Micología, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

0