Ocular Immunology and Inflammation,
Journal Year:
2021,
Volume and Issue:
31(1), P. 39 - 43
Published: Oct. 12, 2021
To
investigate
the
pupillary
diameter
and
light
response
in
patients
who
have
recovered
from
COVID-19.Thirty
two
eyes
of
32
with
a
history
COVID-19
last
months
age
sex-matched
healthy
controls
were
included
this
prospective
study.
All
had
neurological
symptoms.
Dynamic
static
pupillometry
measurements
performed
Sirius
(CSO,
Italy)
corneal
topography
device.Patients
higher
mean
scotopic,
mesopic,
photopic
pupil
diameters
compared
to
(p
=
.01,
p
.04,
.02,
respectively).
In
dynamic
analysis,
0th,
2th,
8th
16th
second
There
no
differences
average
speed
dilatation
>
.05).Our
findings
suggest
that
response,
an
indicator
autonomic
nervous
system
activity,
may
be
affected
Psychophysiology,
Journal Year:
2022,
Volume and Issue:
59(4)
Published: March 22, 2022
A
variety
of
psychological
and
physical
phenomena
elicit
variations
in
the
diameter
pupil
eye.
Changes
size
are
mediated
by
relative
activation
sphincter
pupillae
muscle
(decrease
diameter)
dilator
(increase
diameter),
innervated
parasympathetic
sympathetic
branches,
respectively,
autonomic
nervous
system.
The
current
guidelines
intended
to
inform
guide
psychophysiological
research
involving
measurement
(1)
summarizing
important
aspects
concerning
physiology
pupil,
(2)
providing
methodological
data-analytic
recommendations,
(3)
briefly
reviewing
that
modulate
pupillary
reactivity.
Because
increased
ease
tractability
measurement,
goal
these
is
promote
accurate
recording,
analysis,
reporting
data
research.
JAMA Ophthalmology,
Journal Year:
2020,
Volume and Issue:
138(11), P. 1135 - 1135
Published: Sept. 24, 2020
Importance
Concussion
diagnosis
remains
clinical,
without
objective
diagnostic
tests
available
for
adolescents.
Known
deficits
in
visual
accommodation
and
autonomic
function
after
concussion
make
the
pupillary
light
reflex
(PLR)
a
promising
target
as
an
physiological
biomarker
concussion.
Objective
To
determine
potential
utility
of
PLR
metrics
biomarkers
Design,
Setting,
Participants
Prospective
cohort
adolescent
athletes
between
ages
12
18
years
recruited
August
1,
2017,
December
31,
2018.
The
study
took
place
at
specialty
program
private
suburban
high
school
included
healthy
control
individuals
(n
=
134)
with
sport-related
(SRC)
98).
Analysis
was
completed
June
30,
2020.
Exposures
Sports-related
pupillometry
assessments.
Main
Outcomes
Measures
Pupillary
(maximum
minimum
diameter,
peak
average
constriction/dilation
velocity,
percentage
constriction,
time
to
75%
redilation
[T75]).
Results
134
98
were
obtained
median
12.0
days
following
injury
(interquartile
range
[IQR],
5.0-18.0
days).
Eight
9
significantly
greater
among
Bonferroni
correction
pupil
diameter:
4.83
mm
vs
4.01
mm;
difference,
0.82;
99.44%
CI,
0.53-1.11;
2.96
2.63
0.33;
99.4%
0.18-0.48;
constriction:
38.23%
33.66%;
4.57;
2.60-6.55;
constriction
velocity:
3.08
mm/s
2.50
mm/s;
0.58;
0.36-0.81;
4.88
3.91
0.97;
0.63-1.31;
dilation
1.32
1.22
0.10;
0.00-0.20;
1.83
1.64
0.19;
0.07-0.32;
T75:
1.81
seconds
1.51
seconds;
0.30;
0.10-0.51).
In
exploratory
analyses,
sex-based
differences
observed,
girls
exhibiting
longer
T75
(1.96
1.63
0.02-0.65).
Among
individuals,
diminished
(eg,
smaller
maximum
size
3.81
4.22
−0.41;
−0.77
0.05)
observed
exercise.
Conclusions
Relevance
These
findings
suggest
that
enhancement
characterize
acute
concussion,
while
exercise
produced
sizes
overall
slowing
metrics,
presumably
associated
fatigue.
Quantifiable
measures
may
serve
future
physiologic
athlete.
Frontiers in Psychiatry,
Journal Year:
2020,
Volume and Issue:
11
Published: Sept. 17, 2020
As
our
society
is
ageing
globally,
neurodegenerative
disorders
are
becoming
a
relevant
issue.
Assessment
of
saccadic
eye
movement
could
provide
objective
values
to
help
understand
the
symptoms
disorders.
HTC
Corporation
launched
new
virtual
reality
(VR)
headset,
VIVE
Pro
Eye,
implementing
an
infrared-based
tracking
technique
together
with
VR
technology.
The
purpose
this
study
evaluate
whether
device
can
be
used
as
assessment
tool
and
investigate
technical
features
tracking.
We
developed
measurement
system
simple
environment
on
Unity
design
platform,
following
internationally
proposed
standard
saccade
protocol.
then
measured
7
healthy
young
adults
analyse
oculo-metrics
latency,
peak
velocity,
error
rate
pro-
anti-saccade
tasks:
120
trials
in
each
task.
calculated
these
parameters
based
detection
algorithm
that
we
have
previous
studies.
Consequently,
results
revealed
latency
220.40
±
43.16
ms,
velocity
357.90
111.99
◦/s,
0.24
0.41
%
for
pro-saccade
task,
343.35
76.42
318.79
116.69
0.66
0.76
In
addition,
observed
pupil
diameter
4.30
1.15
mm
(left
eye)
4.29
1.08
(right
4.21
1.04
4.22
0.97
Comparing
between
descriptive
statistics
studies
suggests
Eye
function
since
range
or
close
Nonetheless,
found
limitations
especially
about
time-related
parameters.
Further
improvements
software
hardware
protocol,
more
measurements
diverse
age-groups
people
different
health
conditions
warranted
enhance
whole
movement.
Virtual
Reality
(VR)
has
shown
promising
potential
in
many
applications,
such
as
e-business,
healthcare,
and
social
networking.Rich
information
regarding
users'
activities
online
accounts
is
stored
VR
devices.If
they
are
carelessly
unattended,
adversarial
access
will
cause
data
breaches
other
critical
consequences.Practical
user
authentication
schemes
for
devices
dire
need.Current
solutions,
including
passwords,
digital
PINs,
pattern
locks,
mostly
follow
conventional
approaches
general
personal
devices.They
have
been
criticized
deficits
both
security
usability.In
this
work,
we
propose
SoundLock,
a
novel
scheme
using
auditory-pupillary
response
biometrics.During
authentication,
auditory
stimuli
presented
to
the
via
headset.The
corresponding
pupillary
captured
by
integrated
eye
tracker.User's
legitimacy
then
determined
comparing
with
template
generated
during
enrollment
stage.To
strike
balance
between
usability
design,
an
optimization
problem
formulated.Due
its
nonlinearity,
two-stage
heuristic
algorithm
proposed
solve
it
efficiently.The
solution
provides
necessary
guidance
selecting
effective
determining
their
lengths.We
demonstrate
through
extensive
in-field
experiments
that
SoundLock
outperforms
state-of-the-art
biometric
solutions
FAR
(FRR)
low
0.76%
(0.91%)
well
received
among
participants
study.
Trends in Hearing,
Journal Year:
2019,
Volume and Issue:
23
Published: Jan. 1, 2019
The
ability
to
sustain
attention
on
a
task-relevant
sound
source
while
avoiding
distraction
from
concurrent
sounds
is
fundamental
listening
in
crowded
environments.
We
aimed
(a)
devise
an
experimental
paradigm
with
which
this
aspect
of
can
be
isolated
and
(b)
evaluate
the
applicability
pupillometry
as
objective
measure
sustained
young
older
populations.
designed
that
continuously
measured
behavioral
responses
during
25-s
trials.
Stimuli
contained
number
concurrent,
spectrally
distinct
tone
streams.
On
each
trial,
participants
detected
gaps
one
streams
resisting
others.
Behavior
demonstrated
increasing
difficulty
time-on-task
number/proximity
distractor
In
listeners
(N
=
20;
aged
18
35
years),
pupil
diameter
(on
group
individual
level)
was
dynamically
modulated
by
instantaneous
task
difficulty:
Periods
where
performance
revealed
strain
were
accompanied
increased
diameter.
Only
trials
performed
successfully
included
analysis
so
observed
effects
reflect
demands
opposed
failure
attend.
line
existing
reports,
we
global
changes
dynamics
19;
63
79
years)
including
decreased
diameter,
limited
dilation
range,
reduced
temporal
variability.
However,
despite
these
changes,
showed
similar
attentive
tracking
those
listeners.
Overall,
our
results
demonstrate
reliable
time-sensitive
over
long
durations
both
(with
caveats)
Updates in Surgery,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 10, 2025
Abstract
Hyperhidrosis
is
thought
to
result
from
excessive
stimulation
of
sweat
glands
due
increased
sympathetic
activity;
however,
data
on
systemic
responses
following
bilateral
thoracic
sympathectomy
as
the
definitive
treatment
have
not
yet
been
sufficiently
evaluated.
This
study,
designed
a
prospective
cohort
investigation,
included
24
patients
who
underwent
for
palmar
and
axillary
hyperhidrosis
at
our
center
in
2023,
along
with
an
age-matched
control
group
equal
size.
In
group,
pupillometry
measurements
were
performed
1
day
before
surgery
7th
postoperative
day,
while
corresponding
intervals.
Data
analyzed
both
preoperatively
postoperatively
compared
group.
According
Disease
Severity
Scale,
all
had
severe
hyperhidrosis.
Sympathectomy
was
T3
level
9
T4
levels
15
patients.
The
satisfaction
rate
recorded
95.8%.
No
statistically
significant
differences
observed
between
preoperative
those
However,
when
comparing
within
favoring
parasympathetic
activity
noted
latency
contractions
photopic
low
values
(
p
=
0.016
0.038,
respectively).
Our
study
one
pioneering
works
objectively
demonstrate,
through
quantitative
method,
that
enhances
system
response
ocular
region.
Frontiers in Neurology,
Journal Year:
2018,
Volume and Issue:
9
Published: Oct. 29, 2018
Objective:
Cortical
activity,
including
cognitive
and
emotional
processes,
may
influence
pupillary
function.
The
exact
pathways
the
site
of
cortical
innervation
remain
elusive,
however.
We
investigated
effects
select
strokes,
i.e.
ischemic
infarcts
affecting
insular
cortex
prefrontal
eye
field,
on
Methods:
Seventy-four
patients
with
acute
stroke,
consecutively
admitted
to
our
institution
from
March
July
2018,
were
assessed
24
h
after
endovascular
recanalization
therapy
(i.e.,
day
2
stroke),
using
automated
pupillometry.
Stroke
location
volume
clinical
severity
(estimated
by
Alberta
Program
Early
CT
Score
National
Institute
Health
Scale)
recorded.
excluded
posterior
circulation
intracranial
pathology
other
than
midline
shift
computed
tomography
exceeding
5
millimeters
or
a
history
disease.
Pupillometry
data
25
neurologically
normal
myocardial
infarction
acquired
for
control.
Results:
Fifty
stroke
thrombectomy
included
analysis.
Twenty-five
(50%)
had
field
involvement
(group
1,
strategic
infarcts);
located
in
cerebral
areas
2,
infarcts).
light
reflex,
as
measured
constriction
velocity
maximal/minimal
diameters,
was
within
physiological
limits
all
patients,
controls.
However,
while
size
velocities
correlated
subjects,
correlation
dilatation
absent
right-hemispheric
(left
hemisphere
infarcts,
group
1
(r2
=
0.15,
p
0.04),
0.41,
0.0007);
right
0.008,
0.69);
0.12,
0.08);
controls
0.29,
≤
0.0001).
Conclusions:
insula
do
not
impair
reflex
humans.
subtle
changes
occur
when
pupils
dilate
back
baseline,
probably
due
autonomic
dysfunction.
Replication
is
needed
explore
possible
hemispheric
lateralization.
suggest
that
serve
research
model
study
lesions
Clinical and Experimental Optometry,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 7
Published: Jan. 26, 2025
Clinical
relevance
Although
laser
refractive
surgeries
and
multifocal
intraocular
lens
implantation
are
generally
avoided
in
patients
with
diabetic
retinopathy,
a
substantial
proportion
of
well-glycaemic-controlled
type
2
diabetes
mellitus
considered
for
these
procedures.
Pupil
dynamics
play
significant
role
determining
postoperative
satisfaction
patients.