Evaluation of Pupillometric Parameters in Patients with COVID-19 DOI
Yücel Öztürk, Merve Beyza Yıldız, Rüveyde Bolaç

et al.

Ocular Immunology and Inflammation, Journal Year: 2021, Volume and Issue: 31(1), P. 39 - 43

Published: Oct. 12, 2021

To investigate the pupillary diameter and light response in patients who have recovered from COVID-19.Thirty two eyes of 32 with a history COVID-19 last months age sex-matched healthy controls were included this prospective study. All had neurological symptoms. Dynamic static pupillometry measurements performed Sirius (CSO, Italy) corneal topography device.Patients higher mean scotopic, mesopic, photopic pupil diameters compared to (p = .01, p .04, .02, respectively). In dynamic analysis, 0th, 2th, 8th 16th second There no differences average speed dilatation > .05).Our findings suggest that response, an indicator autonomic nervous system activity, may be affected

Language: Английский

Pupillometry to differentiate idiopathic hypersomnia from narcolepsy type 1 DOI Creative Commons
Héloïse Rach, Ève Reynaud,

Ülker Kilic-Huck

et al.

Journal of Sleep Research, Journal Year: 2023, Volume and Issue: 32(5)

Published: April 1, 2023

Idiopathic hypersomnia is poorly diagnosed in the absence of biomarkers to distinguish it from other central subtypes. Given that light plays a main role regulation sleep and wake, we explored retinal melanopsin-based pupil response patients with idiopathic narcolepsy type 1, healthy subjects. Twenty-seven 1 (women 59%, 36 ± 11.5 years old), 83%, 27.2 7.2 old) long total time (> 11/24 hr), 43 controls 58%, 30.6 9.3 were included this study. All underwent pupillometry protocol assess diameter, relative post-illumination melanopsin-driven responses non-visual input pathway. Differences between groups assessed using logistic regressions adjusted on age sex. We found had smaller baseline diameter as compared (p < 0.05). In addition, both (respectively, 31.6 13.9% 33.2 9.9%) (38.7 9.7%), suggesting reduced melanopsin-mediated types 0.01). Both showed response, unlike hypersomnia, also displayed basal diameter. Importantly, size permitted well discriminate specificity = 66.67% sensitivity 72.22%. Pupillometry may aid multi-feature differentiation

Language: Английский

Citations

5

Clinical factors affecting pupillary light reflex parameters: a single‐centre, cross‐sectional study DOI
Masaaki Ishikawa

Ophthalmic and Physiological Optics, Journal Year: 2021, Volume and Issue: 41(5), P. 952 - 960

Published: Aug. 12, 2021

To evaluate the effects of stimulus intensity, aging, sex, smoking and eye symmetry on pupillary light reflex (PLR) parameters.We evaluated 2812 eyes from 1406 subjects in a single-centre, cross-sectional study. PLR data were collected using four different intensities. We prepared two models for each eight parameters, defined model with lowest values Akaike's information criterion (AIC) as being best-fit. Model A was linear regression without adjustment among-individual variability, while B mixed-effects (LMMs) adjusted variability. The coefficients compared.Model showed AIC all parameters best fit. For age symmetry, yielded similar results parameters. sex index, some opposite results, i.e., significant did not.These indicate that are factors affect These should be when evaluating clinical potential diagnostic tool. In addition, adjusting variability due to LMMs can improve fit reduce false positives. This reveal association between increased accuracy.

Language: Английский

Citations

12

Static and dynamic pupil characteristics in pseudoexfoliation syndrome and glaucoma DOI
Kemal Tekin, Hasan Kızıltoprak, Mehmet Ali Şekeroğlu

et al.

Clinical and Experimental Optometry, Journal Year: 2019, Volume and Issue: 103(3), P. 332 - 338

Published: July 31, 2019

BackgroundTo compare the static and dynamic pupillometry measurements in patients with pseudoexfoliation syndrome (PES), glaucoma (PEG) age‐matched healthy subjects using an automatic quantitative system.MethodsThis prospective, cross‐sectional study consisted of 40 PES, 30 PEG 43 control subjects. Static including scotopic pupil diameter, mesopic low photopic high diameter were undertaken. Subsequently, resting amplitude contraction, latency duration velocity dilation, dilation These compared between groups.ResultsThe scotopic, mesopic, values statistically significantly lower PES controls (p < 0.001). However, these parameters similar > 0.05). The mean within all groups = 0.54). contraction was than Patients also had Additionally, higher when to 0.05).ConclusionThis demonstrated that accumulation pseudoexfoliative material can cause alterations pupillary characteristics progression from may be associated reduced values.

Language: Английский

Citations

12

Combat Sports as a Model for Measuring the Effects of Repeated Head Impacts on Autonomic Brain Function: A Brief Report of Pilot Data DOI Creative Commons
Christopher Kirk, Charmaine Childs

Vision, Journal Year: 2023, Volume and Issue: 7(2), P. 39 - 39

Published: May 4, 2023

Automated pupil light reflex (PLR) is a valid indicator of dysfunctional autonomic brain function following traumatic injury. PLR's use in identifying disturbed repeated head impacts without outwardly visible symptoms has not yet been examined. As combat sport featuring 'sub-concussive' impacts, mixed martial arts (MMA) sparring may provide model to understand such changes. The aim this pilot study was explore which, if any, PLR variables are affected by MMA sparring. A cohort n = 7 athletes (age 24 ± 3 years; mass 76.5 9 kg; stature 176.4 8.5 cm) took part their regular sessions (eight rounds × min: 1 min recovery). both eyes measured immediately pre- and post-sparring using Neuroptic NPi-200. Bayesian paired samples t-tests (BF10 ≥ 3) revealed decreased maximum size 3), minimum 4) reduced latency post-sparring. Anisocoria present prior increased post-sparring, with having different sizes 3-4) constriction velocities 3). These data suggest cause disturbances the absence symptoms. results direction for cohort-controlled studies formally investigate potential changes observed.

Language: Английский

Citations

4

Evaluation of Pupillometric Parameters in Patients with COVID-19 DOI
Yücel Öztürk, Merve Beyza Yıldız, Rüveyde Bolaç

et al.

Ocular Immunology and Inflammation, Journal Year: 2021, Volume and Issue: 31(1), P. 39 - 43

Published: Oct. 12, 2021

To investigate the pupillary diameter and light response in patients who have recovered from COVID-19.Thirty two eyes of 32 with a history COVID-19 last months age sex-matched healthy controls were included this prospective study. All had neurological symptoms. Dynamic static pupillometry measurements performed Sirius (CSO, Italy) corneal topography device.Patients higher mean scotopic, mesopic, photopic pupil diameters compared to (p = .01, p .04, .02, respectively). In dynamic analysis, 0th, 2th, 8th 16th second There no differences average speed dilatation > .05).Our findings suggest that response, an indicator autonomic nervous system activity, may be affected

Language: Английский

Citations

10