Ocular Immunology and Inflammation,
Journal Year:
2021,
Volume and Issue:
31(1), P. 39 - 43
Published: Oct. 12, 2021
To
investigate
the
pupillary
diameter
and
light
response
in
patients
who
have
recovered
from
COVID-19.Thirty
two
eyes
of
32
with
a
history
COVID-19
last
months
age
sex-matched
healthy
controls
were
included
this
prospective
study.
All
had
neurological
symptoms.
Dynamic
static
pupillometry
measurements
performed
Sirius
(CSO,
Italy)
corneal
topography
device.Patients
higher
mean
scotopic,
mesopic,
photopic
pupil
diameters
compared
to
(p
=
.01,
p
.04,
.02,
respectively).
In
dynamic
analysis,
0th,
2th,
8th
16th
second
There
no
differences
average
speed
dilatation
>
.05).Our
findings
suggest
that
response,
an
indicator
autonomic
nervous
system
activity,
may
be
affected
Journal of Sleep Research,
Journal Year:
2023,
Volume and Issue:
32(5)
Published: April 1, 2023
Idiopathic
hypersomnia
is
poorly
diagnosed
in
the
absence
of
biomarkers
to
distinguish
it
from
other
central
subtypes.
Given
that
light
plays
a
main
role
regulation
sleep
and
wake,
we
explored
retinal
melanopsin-based
pupil
response
patients
with
idiopathic
narcolepsy
type
1,
healthy
subjects.
Twenty-seven
1
(women
59%,
36
±
11.5
years
old),
83%,
27.2
7.2
old)
long
total
time
(>
11/24
hr),
43
controls
58%,
30.6
9.3
were
included
this
study.
All
underwent
pupillometry
protocol
assess
diameter,
relative
post-illumination
melanopsin-driven
responses
non-visual
input
pathway.
Differences
between
groups
assessed
using
logistic
regressions
adjusted
on
age
sex.
We
found
had
smaller
baseline
diameter
as
compared
(p
<
0.05).
In
addition,
both
(respectively,
31.6
13.9%
33.2
9.9%)
(38.7
9.7%),
suggesting
reduced
melanopsin-mediated
types
0.01).
Both
showed
response,
unlike
hypersomnia,
also
displayed
basal
diameter.
Importantly,
size
permitted
well
discriminate
specificity
=
66.67%
sensitivity
72.22%.
Pupillometry
may
aid
multi-feature
differentiation
Ophthalmic and Physiological Optics,
Journal Year:
2021,
Volume and Issue:
41(5), P. 952 - 960
Published: Aug. 12, 2021
To
evaluate
the
effects
of
stimulus
intensity,
aging,
sex,
smoking
and
eye
symmetry
on
pupillary
light
reflex
(PLR)
parameters.We
evaluated
2812
eyes
from
1406
subjects
in
a
single-centre,
cross-sectional
study.
PLR
data
were
collected
using
four
different
intensities.
We
prepared
two
models
for
each
eight
parameters,
defined
model
with
lowest
values
Akaike's
information
criterion
(AIC)
as
being
best-fit.
Model
A
was
linear
regression
without
adjustment
among-individual
variability,
while
B
mixed-effects
(LMMs)
adjusted
variability.
The
coefficients
compared.Model
showed
AIC
all
parameters
best
fit.
For
age
symmetry,
yielded
similar
results
parameters.
sex
index,
some
opposite
results,
i.e.,
significant
did
not.These
indicate
that
are
factors
affect
These
should
be
when
evaluating
clinical
potential
diagnostic
tool.
In
addition,
adjusting
variability
due
to
LMMs
can
improve
fit
reduce
false
positives.
This
reveal
association
between
increased
accuracy.
Clinical and Experimental Optometry,
Journal Year:
2019,
Volume and Issue:
103(3), P. 332 - 338
Published: July 31, 2019
BackgroundTo
compare
the
static
and
dynamic
pupillometry
measurements
in
patients
with
pseudoexfoliation
syndrome
(PES),
glaucoma
(PEG)
age‐matched
healthy
subjects
using
an
automatic
quantitative
system.MethodsThis
prospective,
cross‐sectional
study
consisted
of
40
PES,
30
PEG
43
control
subjects.
Static
including
scotopic
pupil
diameter,
mesopic
low
photopic
high
diameter
were
undertaken.
Subsequently,
resting
amplitude
contraction,
latency
duration
velocity
dilation,
dilation
These
compared
between
groups.ResultsThe
scotopic,
mesopic,
values
statistically
significantly
lower
PES
controls
(p
<
0.001).
However,
these
parameters
similar
>
0.05).
The
mean
within
all
groups
=
0.54).
contraction
was
than
Patients
also
had
Additionally,
higher
when
to
0.05).ConclusionThis
demonstrated
that
accumulation
pseudoexfoliative
material
can
cause
alterations
pupillary
characteristics
progression
from
may
be
associated
reduced
values.
Vision,
Journal Year:
2023,
Volume and Issue:
7(2), P. 39 - 39
Published: May 4, 2023
Automated
pupil
light
reflex
(PLR)
is
a
valid
indicator
of
dysfunctional
autonomic
brain
function
following
traumatic
injury.
PLR's
use
in
identifying
disturbed
repeated
head
impacts
without
outwardly
visible
symptoms
has
not
yet
been
examined.
As
combat
sport
featuring
'sub-concussive'
impacts,
mixed
martial
arts
(MMA)
sparring
may
provide
model
to
understand
such
changes.
The
aim
this
pilot
study
was
explore
which,
if
any,
PLR
variables
are
affected
by
MMA
sparring.
A
cohort
n
=
7
athletes
(age
24
±
3
years;
mass
76.5
9
kg;
stature
176.4
8.5
cm)
took
part
their
regular
sessions
(eight
rounds
×
min:
1
min
recovery).
both
eyes
measured
immediately
pre-
and
post-sparring
using
Neuroptic
NPi-200.
Bayesian
paired
samples
t-tests
(BF10
≥
3)
revealed
decreased
maximum
size
3),
minimum
4)
reduced
latency
post-sparring.
Anisocoria
present
prior
increased
post-sparring,
with
having
different
sizes
3-4)
constriction
velocities
3).
These
data
suggest
cause
disturbances
the
absence
symptoms.
results
direction
for
cohort-controlled
studies
formally
investigate
potential
changes
observed.
Ocular Immunology and Inflammation,
Journal Year:
2021,
Volume and Issue:
31(1), P. 39 - 43
Published: Oct. 12, 2021
To
investigate
the
pupillary
diameter
and
light
response
in
patients
who
have
recovered
from
COVID-19.Thirty
two
eyes
of
32
with
a
history
COVID-19
last
months
age
sex-matched
healthy
controls
were
included
this
prospective
study.
All
had
neurological
symptoms.
Dynamic
static
pupillometry
measurements
performed
Sirius
(CSO,
Italy)
corneal
topography
device.Patients
higher
mean
scotopic,
mesopic,
photopic
pupil
diameters
compared
to
(p
=
.01,
p
.04,
.02,
respectively).
In
dynamic
analysis,
0th,
2th,
8th
16th
second
There
no
differences
average
speed
dilatation
>
.05).Our
findings
suggest
that
response,
an
indicator
autonomic
nervous
system
activity,
may
be
affected