The Interoceptive Brain: Confidence Ratings and Accuracy Scores are Independently and Differently Associated With Task‐Related Alpha Power During the Heartbeat Tracking Task

Psychophysiology, Journal Year: 2025, Volume and Issue: 62(4)

Published: April 1, 2025

Cardiac interoception is important for health and can be assessed in terms of accuracy (IAcc) sensibility (IS), at least. While IAcc measures the correspondence between recorded perceived heartbeats, IS means confidence interoceptive perceptions during task. The present study investigated if brain activity heartbeat tracking task associated with as well IS. Specifically, we were interested task-related power (TRP) alpha band (8-12 Hz), known to indicate task-specific cognitive functions such semantic, attentional, sensory processes, IS, respectively. In a sample 30 participants, found relatively higher TRP over left temporal parietal areas (vs. right) Furthermore, observed negative association Lower might that more pronounced processes are linked positive effect (independent from IS), which internal attention beneficial IAcc. We further discuss findings context methodological issues Taken together, pattern favors investigation (i.e., ratings) combination gain better access improve our understanding neural underpinnings (cardiac) interoception.

Language: Английский

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Wave analysis tools

Nature Reviews Methods Primers, Journal Year: 2025, Volume and Issue: 5(1)

Published: April 3, 2025

Language: Английский

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Current findings and perspectives on aberrant neural oscillations in schizophrenia

Psychiatry and Clinical Neurosciences, Journal Year: 2021, Volume and Issue: 75(12), P. 358 - 368

Published: Sept. 24, 2021

There is now consistent evidence that neural oscillation at low- and high-frequencies constitute an important aspect of the pathophysiology schizophrenia. Specifically, impaired rhythmic activity may underlie deficit to generate coherent cognition behavior, leading characteristic symptoms psychosis cognitive deficits. Importantly, generating mechanisms oscillations are relatively well-understood thus enable targeted search for underlying circuit impairments novel treatment targets. In following review, we will summarize assess aberrant in schizophrenia through evaluating studies have utilized Electro/Magnetoencephalography examine during sensory tasks as well resting-state measurements. These data be linked current from post-mortem, neuroimaging, genetics, animal models implicated deficits GABAergic interneurons glutamatergic neurotransmission oscillatory Finally, highlight methodological analytical challenges provide recommendations future research.

Language: Английский

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Rhythms in cognition: The evidence revisited

European Journal of Neuroscience, Journal Year: 2022, Volume and Issue: 55(11-12), P. 2991 - 3009

Published: June 1, 2022

Brain activity abounds with rhythmic patterns (Capilla et al., 2021; Groppe 2013; Keitel & Gross, 2016) that reflect ongoing fluctuations of neuronal excitability (Adrian Matthews, 1934; Bishop, 1932). These rhythms can be described as oscillations cycle through phases at specific frequencies and a certain strength or amplitude (Figure 1). Attempts to account for the functional relevance have gone from associating cognitive function X Y more comprehensive understanding role brain in human everyday experience behaviour (Buzsáki Draguhn, 2004; Fries, 2015; Lakatos 2019; Wang, 2010). accounts support simple, yet fundamental idea: Cognitive functions themselves may intrinsically rhythmic. "The scanning apparatus should intrinsic period operation which identifiable performance brain. [...] In fact, it has order frequency appropriate alpha rhythm brain, shown electroencephalograms. We suspect this is associated form perception, partakes nature sweep rhythm, like process television apparatus." Theories derived these early ideas been reiterated over past 90 years. During time, research focussed on variations framework claiming processes depend offered wealth empirical evidence (Schroeder 2010; VanRullen, 2016; VanRullen Koch, 2003). Rhythmic sampling, implemented rhythms, proposed underlies not only perception but also attention (VanRullen 2007), memory (Staresina 2015), language (Giraud Poeppel, 2012). Linking cognition sampling particularly attractive because allows using global mechanistic principles bridge two different levels explanation: normal function, involves activity, experiences. addition, leaves open possibility actively intervening external stimulation either advance theory, example, close causal (see section 'Can we manipulate take control cognition?'), develop applications clinical interventions, such rehabilitation, brain-computer interfaces. The field, however, immune controversy. available does unequivocally assumed visual processing (Benwell 2017; Chaumon Busch, 2014; Fekete 2018; O'Hare, 1954; Ruzzoli van Diepen Van Walsh, 1952), various theoretical inconsistencies highlighted (Fekete White, 2018). For instance, exact implicated often differ between studies task and/or stimulus characteristics (Chen 2020; Ho Merholz 2022; Ronconi see table 2019), difficult reconcile any simple model fixed, discrete temporal 'frames' (White, Additionally, effect sizes showing periodicity behavioural neural measures tend small, hence line clear, all-or-nothing frame boundaries (Milton Pleydell-Pearce, 2018) utility real-life (Vigué-Guix 2020). Furthermore, literature suffers lack direct replications, pre-registered studies, data, code sharing (Garrett-Ruffin Niso Pavlov 2021), well low statistical power (Button 2013). Finally, publication bias favour statistically significant results distorted undermined reliability published (Szucs Ioannidis, 2017). Despite extensive research, existence remain intensely debated, idea continues attract vast interest. Special Issue, called methodologically principled irrespective their outcome, would contribute clarifying if, under conditions, observed. addition 26 original articles (including conceptual replications), received reviews, methodological advances, position papers. Following our aim re-visit cognition, evaluated primary outcomes 23 tested hypothesis directly. A split picture emerged 11 reporting supportive 12 others null inconclusive findings Figure 2). Within context, here review 36 publications Issue an emphasis how each contribution informs questions controversies wider cognition. doing so, cluster contributions around prevalent topics – Does operate rhythmically? And if processes? majority come influence outcomes. Below, summarise previous lines discuss relevant Issue. Numerous demonstrated by probing time intervals relative reference event. Provided are distributed across wide-enough range sampled densely within range, resulting course submitted spectral analysis rhythmicity. This approach new (e.g., Latour, 1967; Purushothaman 2000) become increasingly popular last decade Dugué Fiebelkorn Landau 2012; Senoussi 2019). refer reader Kienitz al. (2021) overview experimental paradigms employed study during attentive vision both non-human primates. behaviour, debate surrounds potential dissociations frequencies. Michel addressed topic information up down theta (4–7 Hz) (8–12 rhythms. participants performed orientation judgement after non-informative cue (50% validity) indicated target location. observed precision oscillated invalidly cued targets, whilst guess rate validly targets. suggest distinct roles potentially subserving attentional fluctuations. However, authors suggested environmental likely drives spatial resolution, rather than strict succession perceptual snapshots blind gaps 'up' 'down' respectively. possible frequencies, degree fixed depends demands participant state remains unclear. regard, Balestrieri (2021, issue) showed interplay working memory. Rhythms detection were maintenance simultaneous task. Interestingly, was modulated load, oscillating ~7.5 Hz versus 5 high respectively, suggesting might depending allocation limited resources another Morrow Samaha whether occurs alpha-band (Chakravarthi Sokoliuk 2016), capitalising motion-related illusions: flash-lag Fröhlich effect. Indeed, according recently (K. A. Schneider, 2018), supported series 'perceptual moments', duration individual differences illusions. hypothesised effects driven endogenous peak participants, then magnitude illusion correlated individuals. successfully induced illusions all found no correlation Bayesian favoured single underlying oscillatory mechanism could Plöchl examined auditory modality. Their included visual, auditory, bimodal conditions task, closely replicated seminal Fries (2012). Specifically, they capitalised reset (in modality) automatically drive one (left vs. right) streams events uncued locations. fluctuated counter phase attended locations, confirming supramodal processing. modality entirely earlier finding where alpha-range (9 response decision making (Ho combined dichotic oddball paradigm test violating sensory expectations made novel observation stimuli played non-anticipated ear induce subsequent theta-range (7.6 accuracy. update representations following violations expectations. concluded that, although rhythmicity corroborated (growing) number special considerations analytical necessary Brookshire, 2021). need chosen, require large trials participants. On note, der Werf unable replicate (Fiebelkorn Helfrich modified Egly-Driver (Egly 1994) detecting appear end (i.e., location) other space-based, non-cued bar, equidistant bar (object-based, location). No pattern accuracy locations level predictive validity, though exploratory did reveal ~7–8 when cues moderately informative. commentary al.'s study, proposes despite being comparable (Helfrich per condition replication too reliably detect further suggests purely data limiting combining simultaneously recorded electrophysiology (but ten Oever 2022, issue, Fiebelkorn's commentary). Magneto- electroencephalography (M/EEG) allow investigating activity. They enable analyses performance, detection, parameters (phase amplitude) presentation. Most M/EEG revolve question pre-stimulus affect attempting specific, previously untested conditions. EEG presented detected targets rhythmically counter-phase predicted modalities. Benwell challenging letter identification measure subjective awareness trial. confirmed reports (also By contrast, had accuracy, again replicating 1952). Similarly, Michail discrimination corresponding phase. unique aspect experiment long 2.5 s. Accordingly, speculate less lasting several cycles. Sheldon Mathewson set out post-stimulus likelihood guessing. reproduced precisely analysed error distribution models yield separate estimates Conceptually, similar who 'Rhythmicity behaviour'). (Mathewson 2009; Fakche 2022), performance. Instead, 2–7 activities Zazio issue), turn, clear behaviour. resembled (Busch 2009), reported Using MEG source analysis, stimulus-evoked inversely related occipito-temporal areas, whereas localised occipital prefrontal areas. Whilst assessed analysing Es (2020, used vector machine decode (counter/clockwise) signal. classification along theta/alpha frontal eye field parietal cortex contralateral grating stimulus. reflected (reaction times), leaving unknown. Gaillard Ben Hamed neurophysiological argue seems continuously regions alternates periodically center periphery parieto-frontal networks. two-stage positing combination continuous interact conscious percepts (Herzog Vigué-Guix attempted demonstrate interesting features stand section. First, aimed Callaway Yeager (1960), papers looking into idea. closed-loop analyse real-time (bright LED flashes) selectively rhythm. Second, kept eyes closed throughout experiment, amplified facilitated extracting its comparably small sample demonstrating level. reliable estimation parameter managed present accordingly, onset times participant. putative sizable enough practical relevance, signal interface applications. Along phase, recent investigated instantaneous within- between-participant integration temporally proximal (Samaha Postle, 2015) multisensory (audiovisual) (Cecere Keil Senkowski, 2017), theory cycles (VanRullen, 2016). London (2022, extend audiovisual supra-threshold stimuli. occipito-parietal electrodes increased sensitivity, found. results, those (Buergers Noppeney, cast doubt notion determining factor sensitivity perception. provided reviewed thus far provide answer way Behavioural issue frequently perhaps surprising contrasts suggestion (Fiebelkorn, 2021, given represents measurement question. tasks appears quite robust, (see, e.g., D. Schneider (Zazio Therefore, markedly weaker compared effects. aligns Benwell, Keitel, Notably, even subset considered attempts (Plöchl Der least very designs (van mixed. Replication extension key will critical development (Pavlov valuable examples. It crucial methodologies optimised 2022). flaws (such power), important validated replications. ideally trial numbers) terms overall size. collaborative run labs (Open Science Collaboration, 2015). Another future step derive hypotheses existing theories about tasks, states (and not). 1932) predicts is, excitability. arguably case short durations contrast feature longer (Michail Mathewson, issue). challenge define benchmark 'just works', stimuli, trusted fields neuroscience developed conventional eliciting interest, capture (Theeuwes, 1992), cueing (Carrasco, 2011), markers (Ngiam Establishing standard vantage point chart determine affects Manipulating periodic tool sampling. As Quigley reports, dates back Adrian Matthews (1934) Walter (1954), light light-induced responses synchronisation inputs since termed 'entrainment'. entrainment remained pervasive drew strengths major routes: explanatory functions, versatility technique experimenters and, later on, interventionists. Regarding power, Dynamic Attending Theory, posits internal oscillators rhythms) synchronise (Jones Boltz, 1989; Henry Herrmann, 2014). Once established, synchronised cycling optimal cortical coincide upcoming facilitates Lakatos, 2009). widely promoted general interactions input (Lakatos Tavano emblematic crucially underlie ability tune segment understand speech Rimmele Hauswald 2020, From perspective experimenters, versatile method directly manipulating Next stimulation, magnetic electrical non-invasive (NIBS) (Thut, Schyns, 2011). prospect influencing inspired interventions pathological please Tichko (2020) gamma-frequency (40 attempt counteract pathophysiologies linked Alzheimer's disease (Iaccarino strong integrating music-based currently therapy. enthusiastically overall, unclear, implementing applies circumscribed situations. One significance benefits beyond regularities input. implements selective (Calderone 2013), facilitate behaviourally providing periods Barne predictably recurring (here: tone frequency) lead higher predictable features, embedded regular sequences. interleaved instructed compare them probe brief retention interval. Although find benefit non-rhythmic de Graaf Duecker, W. M. Lin, Oetringer, Rassili Ordin, Sun nor pre-probe templates period, cortices intermittent pre-activation anticipation anticipatory anti-phasic activation supports puts maximally excitable (potential) delivery. Moreover, self-sustain ceases. Lin three experiments versions pitch total 181 occurring discriminated faster accurately out-of-phase. first experiments, low-frequency 1–3 Hz. paradigm, Hickok (2015) in-phase easily, entrainment. findings. After amplitude-modulated noise, responded tones constant noise pre-target noise. some periodicities consistently Saberi Hickok, Ordin presenting sequence (linguistic) syllables (non-linguistic) natural sounds similarly affected intermediately sound. neither type exceeded irregular Further hinted reactio

Language: Английский

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Decomposing the role of alpha oscillations during brain maturation

eLife, Journal Year: 2022, Volume and Issue: 11

Published: Aug. 25, 2022

Childhood and adolescence are critical stages of the human lifespan, in which fundamental neural reorganizational processes take place. A substantial body literature investigated accompanying neurophysiological changes, focusing on most dominant feature EEG signal: alpha oscillation. Recent developments signal-processing show that conventional measures power confounded by various factors need to be decomposed into periodic aperiodic components, represent distinct underlying brain mechanisms. It is therefore unclear how each part signal changes during maturation. Using multivariate Bayesian generalized linear models, we examined parameters activity largest openly available pediatric dataset (N=2529, age 5-22 years) replicated these findings a preregistered analysis an independent validation sample (N=369, 6-22 years). First, welldocumented age-related decrease total was replicated. However, when controlling for component, our provided strong evidence increase aperiodic-adjusted power. As reported previous studies, also relative revealed maturational increase, yet indicating underestimation relationship between The intercept slope decreased with increasing were highly correlated Consequently, earlier interpretations reconsidered, as elimination active synapses rather links decreases intercept. Instead, analyses diffusion tensor imaging data indicate related increased thalamocortical connectivity. Functionally, results suggest thalamic control cortical linked improved attentional performance

Language: Английский

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Time-resolved parameterization of aperiodic and periodic brain activity

eLife, Journal Year: 2022, Volume and Issue: 11

Published: Sept. 8, 2022

Macroscopic neural dynamics comprise both aperiodic and periodic signal components. Recent advances in parameterizing power spectra offer practical tools for evaluating these features separately. Although signals vary dynamically express non-stationarity relation to ongoing behaviour perception, current methods yield static spectral decompositions. Here, we introduce Spectral Parameterization Resolved Time (SPRiNT) as a novel method decomposing complex into elements time-resolved manner. First, demonstrate, with naturalistic synthetic data, SPRiNT's capacity reliably recover time-varying features. We emphasize specific strengths compared other time-frequency parameterization approaches based on wavelets. Second, use SPRiNT illustrate how fluctuate across time empirical resting-state EEG data (n=178) relate the observed changes parameters over participants' demographics behaviour. Lastly, demonstrate movement intracranial recordings rodents. foresee responding growing neuroscientific interests of advancing quantitation at natural scales

Language: Английский

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Clinical applications of EEG power spectra aperiodic component analysis: A mini-review

Clinical Neurophysiology, Journal Year: 2022, Volume and Issue: 143, P. 1 - 13

Published: Aug. 28, 2022

Language: Английский

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Oscillatory and Aperiodic Neural Activity Jointly Predict Language Learning

Journal of Cognitive Neuroscience, Journal Year: 2022, Volume and Issue: 34(9), P. 1630 - 1649

Published: Jan. 1, 2022

Abstract Memory formation involves the synchronous firing of neurons in task-relevant networks, with recent models postulating that a decrease low-frequency oscillatory activity underlies successful memory encoding and retrieval. However, to date, this relationship has been investigated primarily face image stimuli; considerably less is known about correlates complex rule learning, as language. Furthermore, work shown nonoscillatory (1/ƒ) functionally relevant cognition, yet its interaction during learning remains unknown. Using spectral decomposition power-law exponent estimation human EEG data (17 women, 18 men), we show for first time 1/ƒ jointly influence word order rules miniature artificial language system. Flexible word-order were associated steeper slope, whereas fixed shallower slope. We also increased theta alpha power predicts relative flexible behavioral performance. Together, these results suggest plays an important role higher-order including processing, grammar modulated by different permutations, which manifest distinct profiles.

Language: Английский

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Memory consolidation during sleep involves context reinstatement in humans

Cell Reports, Journal Year: 2023, Volume and Issue: 42(4), P. 112331 - 112331

Published: April 1, 2023

New memories are not quarantined from each other when first encoded; rather, they interlinked with that were encoded in temporal proximity or share semantic features. By selectively biasing memory processing during sleep, here we test whether context influences sleep consolidation. Participants formed 18 idiosyncratic narratives, linking four objects together. Before also memorized an on-screen position for object. During 12 object-specific sounds unobtrusively presented, thereby cuing the corresponding spatial and impacting recall as a function of initial strength. As hypothesized, find non-cued contextually linked cued changed. Post-cue electrophysiological responses suggest activity sigma band supports reinstatement predicts context-related benefits. Concurrently, context-specific patterns emerge sleep. We conclude reactivation individual evokes their context, consolidation associated knowledge.

Language: Английский

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Aperiodic brain activity and response to anesthesia vary in disorders of consciousness

NeuroImage, Journal Year: 2023, Volume and Issue: 275, P. 120154 - 120154

Published: May 19, 2023

In the human electroencephalogram (EEG), oscillatory power co-exist with non-oscillatory, aperiodic activity. Although EEG analysis has traditionally focused exclusively on power, recent investigations have shown that component can distinguish conscious wakefulness from sleep and anesthetic-induced unconsciousness. This study investigates of individuals in a disorder consciousness (DOC); how it changes response to exposure anesthesia; relates brain's information richness criticality. High-density was recorded 43 DOC, 16 these undergoing protocol propofol anesthesia. The defined by spectral slope density. Our results demonstrate is more informative about participants' level than component, especially for patients suffered stroke. Importantly, pharmacologically induced change 30 45 Hz positively correlated individual's pre-anesthetic consciousness. loss information-richness criticality associated component. During anesthesia, distinguished according their 3-month recovery status. been historically neglected; this research highlights necessity considering measure assessment DOC future seeks understand neurophysiological underpinnings

Language: Английский

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