Brain & Neurorehabilitation,
Journal Year:
2022,
Volume and Issue:
15(2)
Published: Jan. 1, 2022
Parkinson's
disease
(PD)
is
the
second
most
common
neurodegenerative
disorder.
Although
dopaminergic
drugs
are
mainstay
for
improving
PD
symptoms,
there
still
few
effective
disease-modifying
therapies.
With
increasing
prevalence
of
and
rapid
transition
to
an
aging
society,
more
emphasis
needs
be
placed
on
rehabilitation
that
could
slow
progression
combined
with
pharmacological
therapy.
In
this
review,
we
present
update
evidence
related
programs
motor
function,
swallowing
difficulty,
speech
disorders
in
PD.
Aerobic
exercise,
music
therapy,
dance,
virtual
reality,
non-invasive
brain
stimulation
have
been
shown
improve
telerehabilitation
also
feasibly
applied
Recent
studies
effectiveness
expiratory
muscle
strengthening
exercises
Lee
Silverman
Voice
Treatment
difficulty
disorders,
respectively.
many
tried,
limited.
Well-designed
future
randomized
controlled
trials
large
numbers
participants
needed
establish
Biomolecules,
Journal Year:
2021,
Volume and Issue:
11(4), P. 612 - 612
Published: April 20, 2021
Parkinson’s
disease
(PD)
usually
presents
in
older
adults
and
typically
has
both
motor
non-motor
dysfunctions.
PD
is
a
progressive
neurodegenerative
disorder
resulting
from
dopaminergic
neuronal
cell
loss
the
mid-brain
substantia
nigra
pars
compacta
region.
Outlined
here
an
integrative
medicine
health
strategy
that
highlights
five
treatment
options
for
people
with
(PwP):
rehabilitate,
therapy,
restorative,
maintenance,
surgery.
Rehabilitating
begins
following
diagnosis
throughout
any
additional
processes,
especially
vis-à-vis
consulting
physical,
occupational,
and/or
speech
pathology
therapist(s).
Therapy
uses
daily
administration
of
either
dopamine
precursor
levodopa
(with
carbidopa)
or
agonist,
compounds
preserve
residual
dopamine,
other
specific
motor/non-motor-related
compounds.
Restorative
strenuous
aerobic
exercise
programs
can
be
neuroprotective.
Maintenance
complementary
alternative
substances
potentially
support
protect
brain
microenvironment.
Finally,
surgery,
including
deep
stimulation,
pursued
when
PwP
fail
to
respond
positively
options.
There
currently
no
cure
PD.
In
conclusion,
best
treating
hope
slow
progression
strive
achieve
stability
neuroprotection.
The
ultimate
goal
management
program
improve
quality-of-life
person
disease.
Journal of Parkinson s Disease,
Journal Year:
2024,
Volume and Issue:
14(1), P. 135 - 166
Published: Jan. 23, 2024
Background:
Parkinson’s
disease
(PD)
is
a
complex
neurodegenerative
disorder
impacting
everyday
function
and
quality
of
life.
Rehabilitation
plays
crucial
role
in
improving
symptoms,
function,
life
reducing
disability,
particularly
given
the
lack
disease-modifying
agents
limitations
medications
surgical
therapies.
However,
rehabilitative
care
under-recognized
under-utilized
PD
often
only
utilized
later
stages,
despite
research
guidelines
demonstrating
its
positive
effects.
Currently,
there
consensus
regarding
fundamental
topics
related
to
services
PD.
Objective:
The
goal
international
Foundation
Medicine
Task
Force
was
develop
statement
incorporation
rehabilitation
care.
Methods:
Force,
comprised
multidisciplinary
experts
people
directly
affected
by
PD,
met
virtually
discuss
such
as
services,
existing
therapy
literature
gaps
needs.
A
systematic,
interactive,
iterative
process
used
consensus-based
statements
on
core
components
discipline-specific
interventions.
Results:
expert-based
outlines
key
tenets
including
approach
guidance
for
occupational
therapy,
physical
speech
language
pathology/therapy,
psychology/neuropsychology
across
all
stages.
Conclusions:
Rehabilitative
interventions
should
be
an
essential
component
comprehensive
treatment
from
diagnosis
advanced
disease.
Greater
education
awareness
benefits
with
their
partners,
further
evidence-based
scientific
study
are
encouraged.
American Journal of Speech-Language Pathology,
Journal Year:
2024,
Volume and Issue:
33(2), P. 1069 - 1097
Published: Jan. 17, 2024
This
systematic
review
represents
an
update
to
previous
reviews
of
the
literature
addressing
behavioral
management
respiratory/phonatory
dysfunction
in
individuals
with
dysarthria
due
neurodegenerative
disease.
Frontiers in Aging Neuroscience,
Journal Year:
2021,
Volume and Issue:
12
Published: Jan. 14, 2021
Background:
Mild
cognitive
impairment
(MCI)
is
an
early
stage
of
Alzheimer's
disease.
Repetitive
transcranial
magnetic
stimulation
(rTMS)
has
been
widely
employed
in
MCI
research.
However,
there
no
reliable
systematic
evidence
regarding
the
effects
rTMS
on
MCI.
The
aim
this
review
was
to
evaluate
efficacy
and
safety
treatment
Methods:
A
comprehensive
literature
search
nine
electronic
databases
performed
identify
articles
published
English
or
Chinese
before
June
20,
2019.
identified
were
screened,
data
extracted,
methodological
quality
included
trials
assessed.
meta-analysis
using
RevMan
5.3
software.
We
used
GRADE
approach
rate
evidence.
Results:
Nine
studies
comprising
369
patients
included.
showed
that
may
significantly
improve
global
function
(standardized
mean
difference
[SMD]
2.09,
95%
confidence
interval
[CI]
0.94
3.24,
p
=
0.0004,
seven
studies,
n
296;
low-quality
evidence)
memory
(SMD
0.44,
CI
0.16
0.72,
0.002,
six
204;
moderate-quality
evidence).
significant
improvement
executive
attention
(
>
0.05).
Subgroup
analyses
revealed
following:
(1)
targeting
left
hemisphere
enhanced
function,
while
bilateral
hemispheres
memory;
(2)
high-frequency
(3)
a
high
number
treatments
≥20
times
could
memory.
There
dropout
0.05)
between
control
groups.
who
received
had
higher
mild
adverse
(risk
ratio
2.03,
1.16
3.52,
0.01,
317;
Conclusions:
appears
with
have
good
acceptability
effects.
Nevertheless,
these
results
should
be
interpreted
cautiously
due
relatively
small
trials,
particularly
for
low-frequency
rTMS.
Parkinson s Disease,
Journal Year:
2021,
Volume and Issue:
2021, P. 1 - 10
Published: Dec. 27, 2021
Speech
changes
occur
in
the
early
stages
of
Parkinson's
disease
(PD)
and
cause
communication
difficulties,
leading
to
social
isolation.
Lee
Silverman
voice
treatment
(LSVT)
is
a
speech
therapy
approach
designed
improve
patients'
language
capabilities.
The
effectiveness
LSVT
was
compared
with
that
other
interventions
or
no
evaluate
PD
patients
dysarthria.
Systematic
review
meta-analysis
randomized
trials.
Data
Sources:
PubMed,
Embase,
Cochrane
Library,
CNKI,
SinoMed
library
were
searched
from
inception
December
2021
related
LSVT.
Abstracts
screened
reviewed
against
eligibility
criteria
(intervention
group
participants
assessed
based
on
(LSVT
Loud)
control).
Ten
controlled
trials
identified
symptoms
PD.
Compared
respiratory
(RET)
exercise,
training
group,
significant
improvement
detected
sound
press
level
(SPL)
after
immediate
during
reading
vowel
rainbow
passages
an
increase
semitone
standard
deviation
(STSD).
Furthermore,
significantly
increased
participants'
scores
unified
rating
scale
(UPDRS-III)
intelligibility.
This
demonstrated
efficacy
increasing
vocal
loudness
functional
among
individuals
However,
most
studies
included
mild-moderate
Thus,
additional
(RCTs)
large
sample
sizes
are
needed
validate
different
progressions
PD,
including
severe
Digital Health,
Journal Year:
2025,
Volume and Issue:
11
Published: Jan. 1, 2025
Objective
With
advancements
in
digital
health
technologies,
telepractice
has
become
crucial
for
providing
accessible
medical
interventions.
Cerebral
palsy
(CP)
frequently
results
comorbidities
including
dysarthria
and
dysphagia,
leading
to
restrictions
activities.
This
study
evaluates
the
efficacy
of
both
in-person
telepractice-based
intensive
voice
therapy
improving
speech,
swallowing
functions,
related
quality
life
measures
adults
with
CP.
Methods
The
Lee
Silverman
Voice
Treatment
(LSVT)
LOUD
®
,
a
speech-behavior
therapy,
was
administered
16
CP
subjects
(9
men
7
women;
mean
age
=
43.4
±
10.43
years)
via
extended
version
LSVT
(LSVT-X),
program
LSVT-X
(LSVT-X
e-LOUD
).
Outcomes,
maximum
phonation
time
(MPT),
intensity,
diadochokinetic
rate
(DDK),
Handicap
Index
(VHI),
(SWAL-QOL),
Videofluoroscopic
Dysphagia
Scale
(VDS),
were
assessed
pre-
post-treatment.
Results
Significant
improvements
noted
speech
functions:
MPT
(
p
0.006),
intensity
0.004),
DDK
/puh/
0.043),
DDK/puh-tuh-kuh/
0.031).
Swallowing
function
improved
significantly
pharyngeal
phase
on
VDS.
Quality
showed
improvement
physical
0.003),
emotional
0.000),
total
score
VHI
0.001),
fear
0.031),
sleep
0.013),
fatigue
SWAL-QOL
0.019).
These
consistent
groups.
Conclusions
Both
enhance
can
be
utilized
as
therapeutic
intervention
dysphagia
dysarthria,
offering
flexible
treatment
options
aligned
advancements.
