Post-traumatic stress disorder during the Covid-19 pandemic: a national, population-representative, longitudinal study of U.S. adults

npj Mental Health Research, Journal Year: 2024, Volume and Issue: 3(1)

Published: April 10, 2024

Abstract Substantial literature documents the impact of mass traumatic events on post-traumatic stress disorder (PTSD) in populations. However, trajectory PTSD US population during pandemic and association between assets, Covid-19 related stressors, over time remains unclear. The Life Stressors Impact Mental Health Well-Being (CLIMB) is a nationally representative, longitudinal panel adults Spring 2020 ( N = 1270), 2021 1182), 2022 1091). Using four-item PC-PTSD-4, we assessed prevalence probable three years. generalized estimating equations (GEE) logistic regression at each wave, estimated associations demographics, stressors with PTSD. Here report that overall decreases from 22.2% to 16.8% p 0.02). Persons household incomes below $20,000 higher compared other income groups. GEE model shows odds among persons (OR 2.17 (95%CI: 1.35,3.50)) relative $75,000 or more; high stressor scores 2.33 1.72,3.15)) low scores. High are associated 2.69 1.56,4.66)), 4.58 2.52,8.30)), 3.89 2.05,7.38)) This analysis highlights pandemic’s prolonged influence mental health, particularly fewer economic assets those experiencing more pandemic-related stressors. Reducing health disparities requires interventions address inequities.

Language: Английский

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Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS—A multicentre case–control study

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 27, 2025

It is established that patients hospitalised with COVID-19 often have ongoing morbidity affecting activity of daily living (ADL), employment, and mental health. However, little known about the relative outcomes in neurological or psychiatric complications. We conducted a UK multicentre case-control study (controls) those who developed associated acute complications (cases). Among 651 patients, [362 (55%) cases 289 (45%) controls], higher proportion had impairment ADLs (199 [68.9%] vs 101 [51.8%], OR 2.06, p < 0.0002) reported symptoms impacting employment (159 [58.2%] 69 [35.6%] 2.53, 0.0001). There was no significant difference depression anxiety between case control groups overall. For cases, increased risk female sex, age > 50 years hypertension (OR 5.43, 0.003, 3.11, = 0.02, 3.66, 0.04). Those receiving either statins angiotensin converting enzyme (ACE) inhibitors lower 0.09, 0.0006, 0.17, 0.03). Patients worse functional than respiratory alone terms employment. Female years, were outcomes, ACE better outcomes.

Language: Английский

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The mechanism of cognitive dysfunction in patients with COVID-19

Asian Journal of Surgery, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

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Preliminary Evaluation of a Mindfulness Intervention Program in Women with Long COVID Dysautonomia Symptoms

Brain Behavior & Immunity - Health, Journal Year: 2025, Volume and Issue: unknown, P. 100963 - 100963

Published: Feb. 1, 2025

The symptom burden for patients with Long COVID-associated dysautonomia is high, yet there are currently no effective treatments. Mindfulness programs reduce psychological and physical symptoms as well inflammatory gene expression in a variety of medical conditions. study aim was to evaluate the effect six-week mindfulness program women COVID symptoms. Using single arm, pre- posttest design, aged 18-54 years orthostatic intolerance suggestive were recruited from center. Participants attended standardized, six-week, virtual program. An active stand test 6-min walk (6MWT) performed at baseline post-intervention. Self-reported measures mental health collected baseline, post-intervention 4 week follow up included composite autonomic score (COMPASS-31), perceived stress (PSS), anxiety (GAD7), depression (PHQ8), COVID-19 event specific distress (IES-R), fatigue (FSI), sleep (ISI), well-being (MHC-SF), resilience (CD-RISC 10), quality life (SF-20). effects on conserved transcriptional response adversity (CTRA) examined by next-generation sequencing dried whole blood samples. Twenty participants enrolled mean age 39.9 (range 21-52 years). No significant changes observed or 6MWT. A reduction insomnia severity (ISI: 16.6 vs. 13.6; p = 0.001) post-intervention, but scores reverted toward levels 4-week follow-up. improvements seen symptoms, anxiety, stress, depression, well-being, related distress. Pro-inflammatory CTRA decreased significantly pre-to (p 0.004). Declines most among those 3 positive events 0.01), followed 2 0.04) 1 0.05). did not vary function recent illness, hospitalization, demographic characteristics, general history. virtual, may improve dysautonomia. While objective improvement observed, our findings suggest favorable intervention antiviral biology decrease expression. Nonetheless, this population very more attention needed provide multi-modal clinical therapies population.

Language: Английский

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Chronic stress and post-traumatic stress in long COVID: a comparative survey study

Current Psychology, Journal Year: 2025, Volume and Issue: unknown

Published: March 5, 2025

Language: Английский

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