Proceedings of the National Academy of Sciences,
Journal Year:
2024,
Volume and Issue:
121(44)
Published: Oct. 25, 2024
Sexual
reproduction
requires
the
choreographed
interaction
of
female
cells
and
molecules
with
sperm
seminal
fluid.
In
internally
fertilizing
animals,
these
interactions
are
managed
by
specialized
tissues
within
reproductive
tract
(FRT),
such
as
a
uterus,
glands,
storage
organs.
However,
somatic
remain
understudied,
hindering
insight
into
molecular
that
support
fertility.
Here,
we
report
identification,
characterization,
analysis
cell
types
throughout
FRT
in
premier
Genome Biology and Evolution,
Journal Year:
2024,
Volume and Issue:
16(7)
Published: June 28, 2024
Male
seminal
fluid
proteins
often
show
signs
of
positive
selection
and
divergent
evolution,
believed
to
reflect
male-female
coevolution.
Yet,
our
understanding
the
predicted
concerted
evolution
female
reproductive
is
limited.
We
sequenced,
assembled,
annotated
genome
two
species
seed
beetles
allowing
a
comparative
analysis
four
closely
related
these
herbivorous
insects.
compare
general
pattern
in
genes
encoding
with
those
digestive
protein
well-conserved
reference
genes.
found
that
showed
an
overall
ratio
nonsynonymous
synonymous
substitutions
(ω)
similar
conserved
genes,
while
exhibited
higher
ω
values.
Further,
proportion
sites
putatively
under
selection,
explicit
tests
no
difference
relaxed
between
types.
Evolutionary
rate
covariation
analyses
evolutionary
rates
among
were
on
average
more
correlated
than
either
or
Gene
expression
expected
negative
values,
except
for
male-biased
where
this
relationship
was
reversed.
In
conclusion,
relatively
rapid
selection.
contrast,
evolved
at
lower
selective
constraints,
par
known
be
well
conserved.
Although
findings
provide
support
proteins,
they
also
suggest
classes
evolve
partly
distinct
regimes.
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 9, 2024
Abstract
New
genes
arise
through
a
variety
of
evolutionary
processes
and
provide
raw
material
for
adaptation
in
the
face
both
natural
sexual
selection.
De
novo
evolved
emerge
from
previously
non-protein-coding
DNA
sequences,
many
such
are
expressed
male
reproductive
structures.
In
Drosophila
melanogaster
,
several
putative
de
have
essential
roles
spermatogenesis,
but
whether
can
also
impact
sperm
function
beyond
has
not
been
investigated.
We
identified
gene,
katherine
johnson
(
kj
),
that
is
required
high
levels
fertility.
Males
do
express
produce
transfer
stored
normally
females,
these
males
enter
eggs
with
severely
reduced
efficiency.
Using
tagged
transgenic
rescue
construct,
we
observed
KJ
protein
localizes
to
nuclear
periphery
various
stages
detectable
mature
sperm.
These
data
suggest
exerts
an
effect
on
development,
loss
which
results
fertilization
ability.
While
previous
bioinformatic
analyses
suggested
gene
was
restricted
group
orthologs
conserved
synteny,
male-biased
expression,
predicted
features
across
genus,
as
well
instances
some
lineages.
Thus,
potentially
arose
common
ancestor
subsequently
role
D.
.
Our
demonstrate
new
aspect
reproduction
shaped
by
evolution
molecular
foothold
further
investigating
mechanism
entry
into
Article
Summary
How
fruit
fly
poorly
understood.
Here,
identify
efficient
fertilization.
Sperm
lacking
this
gene’s
cannot
eggs.
The
appears
act
during
production,
rather
than
This
study
illustrates
how
newly
affect
important
aspects
provides
insights
sperm-egg
interactions.
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 4, 2024
Abstract
Changes
in
gene
expression
are
a
key
driver
of
phenotypic
evolution,
leading
to
persistent
interest
the
evolution
transcriptomes.
Traditionally,
is
modeled
as
continuous
trait,
leaving
qualitative
transitions
largely
unexplored.
In
this
paper,
we
detail
development
new
Bayesian
inference
techniques
study
evolutionary
turnover
organ-specific
transcriptomes,
which
define
instances
where
orthologous
genes
gain
or
lose
particular
organ.
To
test
these
techniques,
analyze
transcriptomes
two
male
reproductive
organs,
testes
and
accessory
glands,
across
11
species
Drosophila
melanogaster
group.
We
first
discretize
states
by
estimating
probability
that
each
expressed
organ
species.
then
phylogenetic
model
correlated
transcriptome
more
organs
fit
it
state
data.
Inferences
under
show
many
have
gained
lost
organ,
experienced
accelerated
on
different
branches
phylogeny.
Evolution,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 11, 2024
It
remains
unclear
how
variation
in
the
intensity
of
sperm
competition
shapes
phenotypic
and
molecular
evolution
across
clades.
Mice
rats
subfamily
Murinae
are
a
rapid
radiation
exhibiting
incredible
diversity
morphology
production.
We
combined
genomic
data
to
perform
phylogenetic
comparisons
male
reproductive
traits
genes
78
murine
species.
identified
several
shifts
towards
smaller
relative
testes
mass,
presumably
reflecting
reduced
competition.
Several
were
associated
with
suggesting
that
mating
system
selects
for
convergent
suites
related
competitive
ability.
predicted
would
also
drive
more
divergence
species
large
testes.
Contrary
this,
we
found
many
spermatogenesis
evolved
rapidly
mass
due
relaxed
purifying
selection.
While
some
under
recurrent
positive
selection,
selection
played
greater
role
underlying
small
Our
work
demonstrates
postcopulatory
sexual
can
impose
strong
shaping
reproduction,
broad
patterns
may
help
identify
contribute
fertility.
Proceedings of the National Academy of Sciences,
Journal Year:
2024,
Volume and Issue:
121(44)
Published: Oct. 25, 2024
Sexual
reproduction
requires
the
choreographed
interaction
of
female
cells
and
molecules
with
sperm
seminal
fluid.
In
internally
fertilizing
animals,
these
interactions
are
managed
by
specialized
tissues
within
reproductive
tract
(FRT),
such
as
a
uterus,
glands,
storage
organs.
However,
somatic
remain
understudied,
hindering
insight
into
molecular
that
support
fertility.
Here,
we
report
identification,
characterization,
analysis
cell
types
throughout
FRT
in
premier
