Pharmaceutics,
Journal Year:
2021,
Volume and Issue:
13(4), P. 466 - 466
Published: March 30, 2021
The
spread
of
antimicrobial-resistant
pathogens
typically
existing
in
biofilm
formation
and
the
recent
COVID-19
pandemic,
although
unrelated
phenomena,
have
demonstrated
urgent
need
for
methods
to
combat
such
increasing
threats.
New
avenues
research
natural
molecules
with
desirable
properties
alleviate
this
situation
have,
therefore,
been
expanding.
Biosurfactants
comprise
a
group
unique
varied
amphiphilic
microbial
origin
capable
interacting
lipidic
membranes/components
microorganisms
altering
their
physicochemical
properties.
These
features
encouraged
closer
investigations
these
metabolites
as
new
pharmaceutics
potential
applications
clinical,
hygiene
therapeutic
fields.
Mounting
evidence
has
indicated
that
biosurfactants
antimicrobial,
antibiofilm,
antiviral,
immunomodulatory
antiproliferative
activities
are
exploitable
anticancer
treatments
wound
healing
applications.
Some
already
approved
use
food
environmental
fields,
while
others
currently
under
investigation
development
antimicrobials
or
adjuvants
antibiotics
suppression
eradication
strategies.
Moreover,
due
now
being
explored
an
alternative
current
products
procedures
effective
cleaning
handwash
formulations,
antiviral
plastic
fabric
surface
coating
agents
shields
masks.
In
addition,
shown
promise
drug
delivery
systems
medicinal
relief
symptoms
associated
SARS-CoV-2
acute
respiratory
distress
syndrome.
Antioxidants,
Journal Year:
2021,
Volume and Issue:
10(9), P. 1472 - 1472
Published: Sept. 15, 2021
In
the
current
scenario
of
changing
climatic
conditions
and
rising
global
population,
there
is
an
urgent
need
to
explore
novel,
efficient,
economical
natural
products
for
benefit
humankind.
Biosurfactants
are
one
latest
explored
microbial
synthesized
biomolecules
that
have
been
used
in
numerous
fields,
including
agriculture,
pharmaceuticals,
cosmetics,
food
processing,
environment-cleaning
industries,
as
a
source
raw
materials,
lubrication,
wetting,
foaming,
emulsions
formulations,
stabilizing
dispersions.
The
amphiphilic
nature
biosurfactants
shown
be
great
advantage,
distributing
themselves
into
two
immiscible
surfaces
by
reducing
interfacial
surface
tension
increasing
solubility
hydrophobic
compounds.
Furthermore,
their
eco-friendly
nature,
low
or
even
no
toxic
durability
at
higher
temperatures,
ability
withstand
wide
range
pH
fluctuations
make
surfactants
preferable
compared
chemical
counterparts.
Additionally,
can
obviate
oxidation
flow
eliciting
antioxidant
properties,
antimicrobial
anticancer
activities,
drug
delivery
systems,
further
broadening
applicability
pharmaceutical
industries.
Nowadays,
broadly
utilized
improve
soil
quality
improving
concentration
trace
elements
either
mixed
with
pesticides
applied
singly
on
plant
disease
management.
present
review,
we
summarize
research
biosurfactant
compounds,
limiting
factors
production,
application
management,
use
compounds
Biotechnology Letters,
Journal Year:
2021,
Volume and Issue:
43(3), P. 523 - 535
Published: Feb. 3, 2021
Abstract
Macromolecules
are
essential
cellular
components
in
biological
systems
responsible
for
performing
a
large
number
of
functions
that
necessary
growth
and
perseverance
living
organisms.
Proteins,
lipids
carbohydrates
three
major
classes
macromolecules.
To
predict
the
structure,
function,
behaviour
any
cluster
macromolecules,
it
is
to
understand
interaction
between
them
other
through
basic
principles
chemistry
physics.
An
important
macromolecules
present
mixtures
with
surfactants,
where
combination
hydrophobic
electrostatic
interactions
specific
properties
solution.
It
has
been
demonstrated
surfactants
can
help
formation
helices
some
proteins
thereby
promoting
protein
structure
formation.
On
hand,
there
extensive
research
towards
use
solubilize
drugs
pharmaceuticals;
therefore,
evident
many
applications
which
includes
environmental
processes
pharmaceutical
industry.
In
this
review,
we
describe
different
types
relevant
their
physicochemical
from
macromolecules–surfactant
complexes
interactions.
Marine Pollution Bulletin,
Journal Year:
2024,
Volume and Issue:
200, P. 116157 - 116157
Published: Feb. 15, 2024
The
Blue
Growth
strategy
promises
a
sustainable
use
of
marine
resources
for
the
benefit
society.
However,
oil
pollution
in
environment
is
still
serious
issue
human,
animal,
and
environmental
health;
addition,
it
deprives
citizens
potential
economic
recreational
advantages
affected
areas.
Bioremediation,
that
bio-resources
degradation
pollutants,
one
focal
themes
on
which
aims
to.
A
repertoire
marine-derived
bio-products,
biomaterials,
processes,
services
useful
efficient,
economic,
low
impact,
treatments
recovery
oil-polluted
areas
has
been
demonstrated
many
years
research
around
world.
Nonetheless,
although
bioremediation
technology
routinely
applied
soil,
this
not
standardized
market
almost
underexploited.
This
review
provides
summary
opportunities
exploiting
addition
value
to
products
already
validated.
Moreover,
discusses
challenges
limit
actions
can
facilitate
conveying
valuable
products/processes
towards
market.
Frontiers in Chemistry,
Journal Year:
2024,
Volume and Issue:
12
Published: Jan. 19, 2024
Biosurfactants
have
garnered
increased
attention
lately
due
to
their
superiority
of
properties
over
fossil-derived
counterparts.
While
the
cost
production
remains
a
significant
hurdle
surpass
synthetic
surfactants,
biosurfactants
been
anticipated
gain
larger
market
share
in
coming
decades.
Among
these,
glycolipids,
type
low-molecular-weight
biosurfactant,
stand
out
for
efficacy
reducing
surface
and
interfacial
tension,
which
made
them
highly
sought-after
various
surfactant-related
applications.
Glycolipids
are
composed
hydrophilic
carbohydrate
moieties
linked
hydrophobic
fatty
acid
chains
through
ester
bonds
that
mainly
include
rhamnolipids,
trehalose
lipids,
sophorolipids,
mannosylerythritol
lipids.
This
review
highlights
current
landscape
glycolipids
covers
specific
glycolipid
productivity
diverse
range
products
found
global
market.
Applications
such
as
bioremediation,
food
processing,
petroleum
refining,
biomedical
uses,
increasing
agriculture
output
discussed.
Additionally,
latest
advancements
reduction
challenges
utilizing
second-generation
feedstocks
sustainable
also
thoroughly
examined.
Overall,
this
proposes
balance
between
environmental
advantages,
economic
viability,
societal
benefits
optimized
integration
secondary
biosurfactant
production.
Pharmaceuticals,
Journal Year:
2024,
Volume and Issue:
17(1), P. 138 - 138
Published: Jan. 22, 2024
The
rapid
emergence
of
multidrug-resistant
pathogens
worldwide
has
raised
concerns
regarding
the
effectiveness
conventional
antibiotics.
This
can
be
observed
in
ESKAPE
pathogens,
among
others,
whose
multiple
resistance
mechanisms
have
led
to
a
reduction
effective
treatment
options.
Innovative
strategies
aimed
at
mitigating
incidence
antibiotic-resistant
encompass
potential
use
biosurfactants.
These
surface-active
agents
comprise
group
unique
amphiphilic
molecules
microbial
origin
that
are
capable
interacting
with
lipidic
components
microorganisms.
Biosurfactant
interactions
different
surfaces
affect
their
hydrophobic
properties
and
as
result,
ability
alter
microorganisms’
adhesion
abilities
consequent
biofilm
formation.
Unlike
synthetic
surfactants,
biosurfactants
present
low
toxicity
high
biodegradability
remain
stable
under
temperature
pH
extremes,
making
them
potentially
suitable
for
targeted
medical
pharmaceutical
applications.
review
discusses
development
biomedical
therapeutic
uses
antimicrobial
antibiofilm
agents,
addition
considering
synergistic
effect
combination
Furthermore,
anti-cancer
anti-viral
relation
COVID-19
is
also
discussed.
Frontiers in Energy Research,
Journal Year:
2020,
Volume and Issue:
8
Published: July 29, 2020
The
integrated
approach
in
biorefinery
mainly
involves
the
utilization
of
various
agroindustrial
byproducts
as
raw
materials
for
production
several
biobased
products
like
biofuels,
bioenergy,
and
other
high-value
chemicals.
Biofuels
are
backbone
biorefineries,
however,
value-added
biomolecules
such
biopigments,
biopolymers,
biosurfactants,
nutritional
yeast,
etc.
have
been
atracting
a
great
attention.
these
using
traditional
approaches
extensively
studied
last
few
years
due
to
their
promising
application
different
industries
chemical,
food/feed,
pharmaceutical
development
novel
mankind.
Moreover,
lignocellulosic,
starchy
some
is
still
not
fully
explored.
Hence,
there
huge
scope
sustainable
biorefining
make
technology
cost-effective.
lignocellulosic
biomasses
usually
used
biorefineries
composed
cellulose,
hemicellulose,
lignin,
whereas
materials,
besides
starch,
contain,
protein,
lipids
micronutrients.
processing
through
successive
steps
pretreatments,
enzymatic
hydrolysis
fermentation
essentially
required
obtained
final
products.
Considering
certain
bottlenecks
above-mentioned
conventional
approaches,
new
technologies
proposed
improved
pretreatment
biomass
efficient
order
minimize
concentration
toxic
inhibitors
resulting
hydrolysate.
In
this
review,
we
highlighted
on
applications
valuable
