Increased mortality from alcohol use disorder, alcohol‐associated liver disease, and liver cancer from alcohol among older adults in the United States: 2000 to 2021 DOI Creative Commons
Pojsakorn Danpanichkul, Kwanjit Duangsonk, Elaine Tham

et al.

Alcohol Clinical and Experimental Research, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 19, 2024

Abstract Background To investigate the trends in alcohol‐associated liver disease (ALD), cancer from alcohol, and alcohol use disorder (AUD) burden among older adults United States (US). Methods We gathered ALD, AUD prevalence, mortality, age‐standardized rates (ASRs) Global Burden of Disease (GBD) Study 2021 between 2010 2021. estimated annual percent change (APC) with confidence intervals (CIs) for (>70 years) States. The findings were contrasted global estimates categorized by sex state. Results In 2021, there approximately 512,340 cases AUD, 56,990 4490 primary contrast to declining ASRs prevalence mortality burden, these parameters increased From 2000 (APC: 0.54%, 95% CI 0.43% 0.65%), ALD (APC + 0.22% 0.86%), 2.93%, 2.76% 3.11%) increased. Forty states exhibited a rise adults. Conclusion Our highlighted Sates, contrasting decline trends. Public health strategies on which targets adults, are urgently needed.

Language: Английский

Alcohol–Related Liver Disease, Followed by Metabolic Dysfunction–Associated Steatotic Liver Disease, Emerges as the Fastest‐Growing Aetiologies for Primary Liver Cancer in the United States DOI Open Access
Pojsakorn Danpanichkul, Kwanjit Duangsonk, Markos Kalligeros

et al.

Alimentary Pharmacology & Therapeutics, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 5, 2025

ABSTRACT Objective Primary liver cancer (PLC) is projected to be the third leading cause of mortality in United States 2040. We examine burden PLC States, stratified by sex, state and aetiological risk factors. Methods Data on prevalence, incidence, death disability–adjusted life years (DALYs) were extracted from Global Burden Disease Study 2021. Changes these parameters calculated using Joinpoint regression model. Results There 47,970 cases, 31,450 incident 24,770 deaths 576,920 DALYs States. The highest prevalence (16,980), incidence (12,040), (9840) (213,410) due chronic hepatitis C virus infection. From 2000 2021, incidences increased 141%, 136%. Age–standardised rates (ASIRs) (ASDRs) per 100,000 population for increased, primarily driven alcohol–related disease (ALD) (ASIR: annual percent change [APC]: +2.40%; ASDR: APC: +2.22%) metabolic dysfunction–associated steatotic (MASLD) +2.32%; +2.04%). Conclusion has risen past two decades, mainly ALD followed MASLD. These findings offer policymakers an accurate assessment emphasise need targeted factor mitigation, especially regarding alcohol related policy.

Language: Английский

Citations

4
Editorial: Lipidomics in MASLD and MetALD DOI Open Access

Rajalakshmi Govalan,

Vincent Chen

Alimentary Pharmacology & Therapeutics, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 24, 2025

Language: Английский

Citations

1
Early-Onset Gastrointestinal Cancers and Metabolic Risk Factors: Global Trends From the Global Burden of Disease Study 2021 DOI
Pojsakorn Danpanichkul, Kanokphong Suparan, Thanida Auttapracha

et al.

Mayo Clinic Proceedings, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
Liver and Atherosclerotic Risk of Alcohol Consumption in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease DOI
Shaowen Wang,

C. H. Wang,

Yu‐Ming Cheng

et al.

Atherosclerosis, Journal Year: 2025, Volume and Issue: 403, P. 119161 - 119161

Published: March 7, 2025

Language: Английский

Citations

0
The Burden of Alcohol and Substance Use Disorders in Adolescents and Young Adults DOI
Pojsakorn Danpanichkul, Kwanjit Duangsonk, Luis Antonio Díaz

et al.

Drug and Alcohol Dependence, Journal Year: 2024, Volume and Issue: 266, P. 112495 - 112495

Published: Nov. 14, 2024

Language: Английский

Citations

2
The steatotic liver disease burden paradox: unravelling the key role of alcohol DOI
Nikolaj Torp, Mads Israelsen, Aleksander Krag

et al.

Nature Reviews Gastroenterology & Hepatology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 5, 2024

Language: Английский

Citations

1
Alcohol-related liver and extrahepatic malignancies: burden of disease and socioeconomic disparities in 2019 DOI
Pojsakorn Danpanichkul,

Kanokphong Suparan,

Nathorn Chaiyakunapruk

et al.

European Journal of Gastroenterology & Hepatology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

Background Alcohol is linked to various cancers. While many studies have focused on developed countries, the burden of alcohol-related cancers in developing countries remains underexplored. Methods We analyzed data from Global Burden Disease Study (2000–2019) assess mortality and disability-adjusted life years (DALYs) low low-to-middle sociodemographic index (SDI) countries. Results In 2019, there were 494 730 cancer. Low low-middle SDI contributed over 15% global Among multiple types cancer, other pharyngeal these accounted for 30% Primary liver cancer exhibited highest ( n = 16 090) deaths DALYs rates decreased globally between 2000 related increased with a rise all cancers, except primary The most rapidly growing (+2.25%), whereas colorectal evidenced increase (+2.76%). Conclusion has risen SDI, especially Policymakers should focus improving policies as well screening availability tackle associated resource-constrained However, difficulty isolating impact alcohol due limited confounders necessitates caution interpreting findings.

Language: Английский

Citations

0
Increased mortality from alcohol use disorder, alcohol‐associated liver disease, and liver cancer from alcohol among older adults in the United States: 2000 to 2021 DOI Creative Commons
Pojsakorn Danpanichkul, Kwanjit Duangsonk, Elaine Tham

et al.

Alcohol Clinical and Experimental Research, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 19, 2024

Abstract Background To investigate the trends in alcohol‐associated liver disease (ALD), cancer from alcohol, and alcohol use disorder (AUD) burden among older adults United States (US). Methods We gathered ALD, AUD prevalence, mortality, age‐standardized rates (ASRs) Global Burden of Disease (GBD) Study 2021 between 2010 2021. estimated annual percent change (APC) with confidence intervals (CIs) for (>70 years) States. The findings were contrasted global estimates categorized by sex state. Results In 2021, there approximately 512,340 cases AUD, 56,990 4490 primary contrast to declining ASRs prevalence mortality burden, these parameters increased From 2000 (APC: 0.54%, 95% CI 0.43% 0.65%), ALD (APC + 0.22% 0.86%), 2.93%, 2.76% 3.11%) increased. Forty states exhibited a rise adults. Conclusion Our highlighted Sates, contrasting decline trends. Public health strategies on which targets adults, are urgently needed.

Language: Английский

Citations

0