Proceedings of the Royal Society B Biological Sciences,
Journal Year:
2025,
Volume and Issue:
292(2045)
Published: April 1, 2025
Performance
tends
to
decline
with
age,
including
muscle
function
and
stress
tolerance.
Yet,
performance
can
vary
widely
among
individuals
within
the
same
age
group,
showing
that
chronological
does
not
always
represent
biological
age.
To
better
understand
ageing,
we
need
examine
what
drives
some
faster
than
others.
In
order
achieve
this,
first
be
able
predict
whether
an
individual
will
have
a
long
or
short
lifespan.
this
study,
conducted
longitudinal
study
tracking
individual-level
locomotor
activity,
chill-coma
recovery
time,
metabolic
rates,
assessed
early-life
is
linked
lifespan
using
solitary
bee
Megachile
rotundata
.
We
found
activity
times
in
old
adults.
However,
resting
rate
did
change
also
low
cold
tolerance
mass
at
emergence
are
shorter
female
lifespans,
explain
of
variation
population.
Finally,
these
results
show
all
traits
species,
shed
new
light
on
sexual
dimorphism
physiological
ageing.
BioEssays,
Journal Year:
2022,
Volume and Issue:
44(4)
Published: Feb. 5, 2022
Abstract
Although
early‐life
adversity
has
been
associated
with
negative
consequences
during
adulthood,
growing
evidence
shows
that
such
can
also
lead
to
subsequent
stress
resilience
and
positive
fitness
outcomes.
Telomere
dynamics
are
relevant
in
this
context
because
of
the
link
developmental
conditions
longevity.
However,
few
studies
have
assessed
whether
effects
on
telomere
may
relate
adult
dynamics.
We
propose
potential
links
between
could
be
driven
by
constraints
(the
Constraint
hypothesis),
nature/severity
Resilience
or
developmental‐mediated
changes
individual
life‐history
strategies
Pace
Life
hypothesis).
discuss
these
non‐mutually
exclusive
hypotheses,
explore
future
research
directions,
specific
test
hypotheses.
Our
article
aims
expand
our
understanding
evolutionary
role
dynamics,
ageing.
Molecular Ecology,
Journal Year:
2022,
Volume and Issue:
31(23), P. 6018 - 6039
Published: Jan. 26, 2022
Abstract
Human‐driven
environmental
changes
are
affecting
wildlife
across
the
globe.
These
challenges
do
not
influence
species
or
populations
to
same
extent
and
therefore
a
comprehensive
evaluation
of
organismal
health
is
needed
determine
their
ultimate
impact.
Evidence
suggests
that
telomeres
(the
terminal
chromosomal
regions)
sensitive
conditions
have
been
posited
as
surrogate
for
animal
fitness.
Evaluation
use
in
an
applied
ecological
context
still
scarce.
Here,
using
information
from
molecular
occupational
biomedical
studies,
we
aim
provide
ecologists
evolutionary
biologists
with
accessible
synthesis
links
between
human
disturbances
telomere
length.
In
addition,
perform
systematic
review
meta‐analysis
on
studies
measuring
length
wild/wild‐derived
animals
facing
anthropogenic
disturbances.
Despite
relatively
small
number
date,
our
revealed
significant
negative
association
(−0.092
[−0.153,
−0.031];
n
=
28;
k
159).
Yet,
biomarker
understand
impact
limited.
We
propose
some
research
avenues
will
help
broadly
evaluate
suitability:
(i)
further
causal
link
telomeres;
(ii)
investigating
implications,
terms
fitness
performance,
given
anthropogenically
disturbed
scenarios;
(iii)
better
understanding
underlying
mechanisms
dynamics.
Future
these
facets
ultimately
role
markers
Biology Letters,
Journal Year:
2025,
Volume and Issue:
21(2)
Published: Feb. 1, 2025
It
is
important
to
know
whether
organs
age
at
the
same
rate
and
are
equally
affected
by
developmental
conditions
as
this
provides
insights
into
causes
of
ageing.
However,
data
on
organ-specific
telomere
dynamics
remain
scant.
In
a
previous
study
early
life
amphibian
Xenopus
laevis
,
we
detected
changes
in
lengths
gut
cells,
while
liver,
heart
muscle
telomeres
were
unchanged;
larval
rearing
temperature
had
minimal
effects.
Here,
extend
that
examine
four
treatments
from
70-day
post-metamorphic
juvenile
through
sexually
mature
(2-year-old)
adults.
Telomeres
shortened
adult
gut,
hindlimb
muscle.
contrast,
liver
did
not
change
with
but
shorter
if
was
warm.
Organ
influenced
sex
only
Warmer
temperatures
also
associated
longer
juveniles.
Hence,
pre-metamorphic
can
influence
dynamics,
loss
between
stages
occurs
different
those
earlier
life.
These
findings
indicate
existence
organ-dependent
ageing
rates
across
lifetimes,
potentially
related
environmental
history.
Proceedings of the Royal Society B Biological Sciences,
Journal Year:
2025,
Volume and Issue:
292(2045)
Published: April 1, 2025
Performance
tends
to
decline
with
age,
including
muscle
function
and
stress
tolerance.
Yet,
performance
can
vary
widely
among
individuals
within
the
same
age
group,
showing
that
chronological
does
not
always
represent
biological
age.
To
better
understand
ageing,
we
need
examine
what
drives
some
faster
than
others.
In
order
achieve
this,
first
be
able
predict
whether
an
individual
will
have
a
long
or
short
lifespan.
this
study,
conducted
longitudinal
study
tracking
individual-level
locomotor
activity,
chill-coma
recovery
time,
metabolic
rates,
assessed
early-life
is
linked
lifespan
using
solitary
bee
Megachile
rotundata
.
We
found
activity
times
in
old
adults.
However,
resting
rate
did
change
also
low
cold
tolerance
mass
at
emergence
are
shorter
female
lifespans,
explain
of
variation
population.
Finally,
these
results
show
all
traits
species,
shed
new
light
on
sexual
dimorphism
physiological
ageing.
