Cited by Epigenetic then genetic variations underpin rapid adaptation of oyster populations (<i>Crassostrea gigas</i>) to Pacific Oyster Mortality Syndrome (POMS)

Unraveling host regulation of gut microbiota through the epigenome–microbiome axis DOI

Michael Le Pepke, Søren B. Hansen, Morten T. Limborg

et al.

Trends in Microbiology, Journal Year: 2024, Volume and Issue: 32(12), P. 1229 - 1240

Published: June 5, 2024

Recent studies of dynamic interactions between epigenetic modifications a host organism and the composition or activity its associated gut microbiota suggest an opportunity for to shape microbiome through alterations that lead changes in gene expression noncoding RNA activity. We use insights from microbiota-induced review potential epigenetically regulate microbiome, which bidirectional 'epigenome–microbiome axis' emerges. This axis embeds environmentally induced variation, may influence adaptive evolution host–microbe interactions. furthermore present our perspective on how epigenome–microbiome can be understood investigated within holo-omic framework with applications applied health food sciences.

Language: Английский

Citations

Epigenetic variations are more substantial than genetic variations in rapid adaptation of oyster to Pacific oyster mortality syndrome DOI

Janan Gawra, A. Valdivieso, Fabrice Roux

et al.

Science Advances, Journal Year: 2023, Volume and Issue: 9(36)

Published: Sept. 8, 2023

Disease emergence is accelerating with global changes. Understanding by which mechanisms host populations can rapidly adapt will be crucial for management practices. Pacific oyster mortality syndrome (POMS) imposes a substantial and recurrent selective pressure on populations, rapid adaptation may arise through genetics epigenetics. In this study, we used (epi)genome-wide association mapping to show that oysters differentially exposed POMS displayed genetic epigenetic signatures of selection. Consistent higher resistance POMS, the genes targeted included many in several pathways related immunity. By combining correlation, DNA methylation quantitative trait loci, variance partitioning, revealed third phenotypic variation was explained interactions between information, ~14% genome, up 25% epigenome alone. Similar genetically based adaptation, notably governing immune responses contribute substantially hosts emerging infectious diseases.

Language: Английский

Citations

Adapting to climate with limited genetic diversity: Nucleotide,DNAmethylation and microbiome variation among populations of the social spiderStegodyphus dumicola DOI

Anne Aagaard, Shenglin Liu, Tom Tregenza

et al.

Molecular Ecology, Journal Year: 2022, Volume and Issue: 31(22), P. 5765 - 5783

Published: Sept. 16, 2022

Understanding the role of genetic and nongenetic variants in modulating phenotypes is central to our knowledge adaptive responses local conditions environmental change, particularly species with such low population diversity that it likely limit their evolutionary potential. A first step towards uncovering molecular mechanisms underlying population-specific environment carry out association studies. We associated climatic variation genetic, epigenetic microbiome populations a social spider extremely standing diversity. identified are strongly variation, average temperature, pattern consistent adaptation. Variation DNA methylation many genes was correlated wide set climate parameters, thereby revealing different associations than variants, which show strong correlations more restricted range parameters. levels were largely independent cis-genetic overall structure, suggesting can work as an mechanism. Microbiome composition also but most precipitation-related factors. Our results suggest for both shaping phenotypic environments.

Language: Английский

Citations

Genomic and Methylomic Signatures Associated With the Maintenance of Genome Stability and Adaptive Evolution in Two Closely Allied Wolf Spiders DOI

Qing Zuo, Runbiao Wu,

Lina Sun

et al.

Molecular Ecology Resources, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 20, 2025

ABSTRACT Pardosa spiders, belonging to the wolf spider family Lycosidae, play a vital role in maintaining health of forest and agricultural ecosystems due their function pest control. This study presents chromosome‐level genome assemblies for two allied species, P. laura agraria . Both species' genomes show notable expansion helitron transposable elements, which contributes large sizes. Methylome analysis indicates that has higher overall DNA methylation levels compared may not only aids element‐driven but also positively affects three‐dimensional organisation after transposon amplification, thereby potentially enhancing stability. Genes associated with hyper‐differentially methylated regions (compared ) are enriched functions related mRNA processing energy production. Furthermore, combined transcriptome methylome profiling uncovered complex regulatory interplay between gene expression, emphasising important body regulation expression. Comparative genomic shows significant cuticle protein detoxification‐related families , improve its adaptability various habitats. provides essential methylomic insights, offering deeper understanding relationship elements stability, illuminating adaptive evolution species differentiation among spiders.

Language: Английский

Citations

Non-Acarine Arachnids in the Ndumo Game Reserve: Celebrating 100 Years of Research DOI

Charles R. Haddad

African Journal of Wildlife Research, Journal Year: 2025, Volume and Issue: 55(sp1)

Published: Feb. 5, 2025

Language: Английский

Citations

The evolutionary consequences of interactions between the epigenome, the genome and the environment DOI

Pierre Baduel, Iris Sammarco, Rowan D. H. Barrett

et al.

Evolutionary Applications, Journal Year: 2024, Volume and Issue: 17(7)

Published: July 1, 2024

Abstract The epigenome is the suite of interacting chemical marks and molecules that helps to shape patterns development, phenotypic plasticity gene regulation, in part due its responsiveness environmental stimuli. There increasing interest understanding functional evolutionary importance this sensitivity under ecologically realistic conditions. Observations epigenetic variation abounds natural populations have prompted speculation it may facilitate responses rapid perturbations, such as those occurring climate change. A frequent point contention whether variants reflect genetic or are independent it. genome often appear tightly linked interdependent. While many changes genetically determined, converse also true, with DNA sequence influenced by presence marks. Understanding how epigenome, environment interact one another therefore an essential step explaining broader consequences epigenomic variation. Drawing on results from experimental comparative studies carried out diverse plant animal species, we synthesize our current these factors populations, a focus identifying similarities differences between taxonomic groups. We describe main components they vary within taxa. review interacts features determinants, role transposable elements (TEs) integrating environment. And look at recent investigating interactions. Although differentiation nature likely result drift selection stochastic epimutations, there growing evidence significant fraction can be stably inherited could contribute evolution independently

Language: Английский

Citations

Food provisioning to Pardosa spiders decreases the levels of tissue-resident endosymbiotic bacteria DOI

Milan Řezáč, Veronika Řezáčová, Nela Gloríková

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: April 28, 2023

The diversity, host specificity, and physiological effects of endosymbiotic bacteria in spiders (Araneae) are poorly characterized. We used 16S rDNA sequencing to evaluate endosymbionts the cephalothorax legs a wolf spider Pardosa agrestis. tested feeding once or twice daily with fruit flies, aphids, starved compared them those syntopically occurring palustris. increased traveled distance up five times some groups provisioned food relative control. Shannon diversity t-test revealed significant differences between these component communities two species. frequency but not dominance decreased alpha OTUs. obligate facultative were present all analyzed individuals represented mostly by Rickettsiella, Rhabdochlamydia, Spiroplasma, intracellular parasite Legionella. Vertically transmitted less common, Wolbachia pipientis Rickettsia sp. H820. abundance Mycoplasma spp. was negatively correlated killed aphids. In conclusion, tissues tremendously diverse assemblages bacteria, including endosymbionts, yet unknown phenotypic effects.

Language: Английский

Citations

Does ecological drift explain variation in microbiome composition among groups in a social host species? DOI

Clémence Rose, M. Lund, Andreas Schramm

et al.

Journal of Evolutionary Biology, Journal Year: 2023, Volume and Issue: 36(12), P. 1684 - 1694

Published: Sept. 30, 2023

Within a given species, considerable inter-individual, spatial, and temporal variation in the composition of host microbiome exists. In group-living animals, social interactions homogenize among group members, nevertheless divergence related groups arise. Such can result from deterministic stochastic processes. Stochastic changes, or ecological drift, occur symbionts with potential for colonizing within individual hosts, drive hosts groups. We tested whether drift associated dispersal foundation new cause between natal newly formed spider Stegodyphus dumicola. simulated initiation by splitting field-collected nests into 1, 3, 10 individuals respectively, compared after 6 weeks using 16S rRNA gene sequencing. Theory predicts that increases decreasing size. found single founders was more dissimilar than kept groups, supporting this prediction. Divergence nest mainly driven higher number non-core symbionts. This suggests microbiomes arise during process formation founders, which could explain existence among-group wild. Individual appear to harbour relative abundances small some are possible pathogens. These vary occurrence size, indicating dynamics influence various core differently.

Language: Английский

Citations

Preliminary characterization of biomolecular processes related to plasticity in Acyrthosiphon pisum DOI

Vincenzo De Fabrizio, Vincenzo Trotta,

Luigi Pariti

et al.

Heliyon, Journal Year: 2023, Volume and Issue: 10(1), P. e23650 - e23650

Published: Dec. 13, 2023

Global warming strongly impacts many organisms' development, distribution and population structure. This problem has attracted the attention of scientists to understand study its actual effects, especially on insects influenced by environmental temperatures. Aphids are a model for studies genetics physiology stress. characterized parthenogenetic reproduction, which limits effects recombination evolutionary processes, have shown resistance various biotic abiotic stresses. was based hypothesis that aphids optimized, over time, genetic mechanisms capable give them plasticity through genome modifications mediated transposition. To evaluate heat stress, expression levels transposases methylases were analyzed in mothers daughters. Our results show after four days from thermal shock, methylation decreases both daughters, while transposition significantly increases thus generating gene variability, essential adaptation.

Language: Английский

Citations

Microbiome and epigenetic variation in wild fish with low genetic diversity DOI

Ishrat Z. Anka, Tamsyn M. Uren Webster, Waldir M. Berbel‐Filho

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: June 3, 2024

Abstract Non-genetic sources of phenotypic variation, such as the epigenome and microbiome, could be important contributors to adaptive variation for species with low genetic diversity. However, little is known about complex interaction between these factors diversity host, particularly in wild populations. Here, we examine skin microbiome composition two closely-related mangrove killifish different mating systems (self-fertilising outcrossing) under sympatric allopatric conditions. This allows us partition influence genotype environment on their (previously described) epigenetic profiles. We find community are strongly shaped by and, a lesser extent, species-specific influences. Heterozygosity alpha diversity, but not associated fluctuating asymmetry traits related performance (vision) behaviour (aggression). Our study identifies that proportion differentiation unrelated evidence an associative relationship suggests both mechanisms potentially contribute

Language: Английский

Citations