Life-long music and dance relationships and therapeutic impressions in individuals with and without mild cognitive impairment to inform the design of music- and dance-based therapies DOI Creative Commons
Meghan E. Kazanski, Sahrudh Dharanendra, Michael C. Rosenberg

et al.

Journal of Alzheimer s Disease, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

Background No effective therapies exist to prevent neurodegenerative mild cognitive impairment (MCI) related Alzheimer's disease. Therapies integrating music and/or dance are promising non-pharmacological options effectively mitigate decline. Objective To deepen our understanding of individuals’ relationships (i.e., histories, experiences, and attitudes) with dance, in order incorporate such knowledge into the design music- dance-based interventions, thereby improving therapeutic outcomes. Methods Eleven older adults MCI five their care partners/ spouses (4 M/12F; Black: n = 4, White: 10, Hispanic/Latino: 2; Age: 71.4 ± 9.6 years) first completed questionnaires, then participated focus groups that captured aspects dance. Emergent themes were extracted from four major topics, including: (1) experience history, (2) enjoyment preferences, (3) confidence barriers, (4) impressions as tools. Results Thematic analysis revealed participants’ positive potential citing perceived neuropsychological, emotional, physical benefits. Participants viewed integral lives, identities within a culture, family, and/ or community. also identified lifelong engagement barriers that, conjunction negative feedback, instilled persistent low self-efficacy regarding dancing active engagement. Questionnaires verified moderately-strong relationships, which strongest passive forms (e.g., listening). Conclusions Our findings support associated perceptions toward therapy may offer valuable insights enhance efficacious engaging for individuals MCI.

Language: Английский

Comparative efficacy of seven nonpharmacological interventions on global cognition in older adults with and without mild cognitive impairment: a network meta-analysis of randomized controlled trials DOI Creative Commons
Ji‐Woo Seok, Gahye Kim, Jaeuk U. Kim

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: April 10, 2024

Abstract To maintain current cognitive function and access greater reserves, nonpharmacological interventions may be a viable alternative for older adults with or without impairment. This study aimed to compare different enhancing global cognition, including mind–body exercise, physical non-invasive brain stimulation, training intervention (CTI), acutherapy (ACU), meditation, music therapy, by applying network meta-analysis (NMA). Sixty-one randomized controlled trials evaluating the efficacy of on cognition in mild decline were selected. An NMA was conducted interventions. The revealed that exercise (standardized mean difference, 1.384; 95% confidence interval, 0.777–1.992); ACU (1.283; 0.478–2.088); meditation (0.910; 0.097–1.724); stimulation (1.242; 0.254–2.230); CTI (1.269; 0.736–1.802); (0.977; 0.212–1.742), showed positive effects compared passive controls. There no significant differences between efficacies other Nonpharmacological potentially enhance through various pathways, such as memorizing movements plasticity reducing stress adult population. Additional studies are needed clarify impact variables, methods psychological variables.

Language: Английский

Citations

4
Cognitive effects of piracetam in adults with memory impairment: A systematic review and meta-analysis DOI
Felipe Gouhie,

Karina Oliveira Barbosa,

Amanda Borges Rufino Cruz

et al.

Clinical Neurology and Neurosurgery, Journal Year: 2024, Volume and Issue: 243, P. 108358 - 108358

Published: May 31, 2024

Language: Английский

Citations

4
Effectively capturing memory deficits: New advances in the use of the In-out-Test for cognitive Test post-stroke DOI
Fei Xiao, Jing Zhang, Yue Shi

et al.

Applied Neuropsychology Adult, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 9

Published: Jan. 17, 2025

This study evaluated the reliability and validity of In-Out-Test for detecting episodic memory deficits in stroke patients explored its potential as a clinical test. A total 75 120 healthy controls underwent tests, including Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Picture-Based Memory Impairment Screen (PMIS), In-Out-Test. Reliability metrics (Cronbach's α, inter-scorer reliability, test-retest reliability), criterion validity, corrected item-total correlation, hierarchical regression analysis ROC curve were performed to determine sensitivity specificity Stroke scored lower across all tests (p < 0.001), with largest difference (d = 0.99). The correlated strongly other cognitive (r 0.79-0.85 patients; r 0.66-0.78 controls). It explained an additional 4.5% variance MoCA-MIS scores 0.001). was high α 0.835; inter-rater ICCs 0.911-0.925; 0.764-0.802). showed AUC 0.747, 0.708 0.680 at cutoff 10.5. Preliminary findings indicated that impairments patients, warranting further validation larger cohorts.

Language: Английский

Citations

0
Music moves: Ettlingen dementia study – a pragmatic randomised controlled trial DOI
Elsa A. Campbell,

J R Hogue,

Jian Du

et al.

Aging & Mental Health, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 12

Published: Jan. 21, 2025

Due to the limited effectiveness of pharmacological treatment, there is a growing need explore non-pharmacological psychosocial interventions such as music therapy when treating behavioural and psychological symptoms dementia (BPSD). We randomised 57 nursing home residents into individual active plus standard care (aMT), receptive with tactile sound vibration (rMT), or control group (CG). A trained therapist provided 12 sessions over 6 weeks. The outcomes (BPSD; depression; quality life; medical system usage; activities daily living; engagement) were measured at baseline (0 week), post-intervention (6 weeks), follow-up (12 weeks). results indicated small beneficial effects for BPSD in aMT rMT follow-up, effect total musical engagement rMT, negative verbal communication usage CG. Both methods showed promise managing increasing during therapy. may be more suited advanced stages dementia. Future studies should evaluate appropriateness each intervention according disease severity.

Language: Английский

Citations

0
Potential common targets of music therapy intervention in neuropsychiatric disorders: the prefrontal cortex-hippocampus -amygdala circuit (a review) DOI Creative Commons
Yang Dan, Ying Xiong, Danghan Xu

et al.

Frontiers in Human Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: Feb. 3, 2025

As life becomes more stressful, neurological disorders, psychiatric and comorbidities of the two are becoming a concern. Multiple neuropsychiatric disorders share same mental somatic dysfunction may involve common brain circuits mechanistic targets. Music therapy, as an art form with proven efficacy, low cost few side effects, is promoted for use in interventions disorders. This be closely related to release signaling molecules such monoamine neurotransmitters, glutamatergic system, gut-microbiota-brain axis, pro-inflammatory cytokines endogenous opioid peptide system. However, fewer studies have mentioned main targets music promote functional changes regions. Therefore, this paper review mechanisms by which therapy interacts prefrontal cortex-hippocampus-amygdala circuit through aforementioned molecules. It also hypothesized that glial cells, mitochondria microRNAs microscopic musical intervention The aim give new ideas future research into biological

Language: Английский

Citations

0
Stress-related neurodegenerative diseases: Molecular mechanisms implicated in neurodegeneration and therapeutic strategies DOI
Maryam Azarfarin, Nasrollah Moradikor, Sara Salatin

et al.

Progress in brain research, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0
Prescribing Music as an Adjunctive Treatment DOI
Rhonda Winegar,

Dustin Hixenbaugh

The Journal for Nurse Practitioners, Journal Year: 2025, Volume and Issue: unknown, P. 105349 - 105349

Published: March 1, 2025

Language: Английский

Citations

0
Music Therapy in Depression: Exploring Mechanisms and Efficacy in Rat Models DOI Creative Commons

Jaden P. Le,

Wei Deng, Tao Le

et al.

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(4), P. 338 - 338

Published: March 25, 2025

Background/Objectives: Depression is a common mental disorder, and traditional treatments are often associated with side effects, making it particularly important to identify safe effective alternative therapies. As non-invasive intervention, music therapy has attracted increasing attention in the field of health recent years. Methods: This study aimed explore effectiveness interventions alleviating depressive symptoms through systematic review their effects on rat model depression. The databases PubMed, Embase, Medline, PsycINFO, Scopus, Web Science, Cochrane Library, Google Scholar, Ovid MEDLINE were searched for publications dated between January 2010 November 2024. Results: First, construction methods behavioral test approaches used models introduced analyzed. Second, physiological biochemical indexes, as well neural structure function depressed rats, discussed. types influencing behaviors rats also summarized Finally, current concerns challenges translating into clinical applications depression reviewed, alongside future prospects its development. Conclusions: It anticipated that this will pave way both basic research application treatment

Language: Английский

Citations

0
Proof-of-Concept Study on the Use of Virtual Reality with Evocative and Aesthetic Content for Elderly Individuals with Cognitive Decline DOI Creative Commons
F. Carlomagno, Vitoantonio Bevilacqua, Antonio Brunetti

et al.

Applied Sciences, Journal Year: 2025, Volume and Issue: 15(9), P. 4627 - 4627

Published: April 22, 2025

Recent technological advances have introduced novel therapeutic interventions for Alzheimer’s disease (AD). This study introduces a virtual reality (VR) intervention consisting of aesthetically pleasing and relaxing immersive videos paired with evocative music patients or without cognitive decline. The goal this is to improve the mood, evoke autobiographical memories in, enhance overall well-being elderly individuals, across stages decline (from absent severe). Twenty-one participants (5 cognitively healthy, 13 mild decline, 2 moderate 1 severe decline) were exposed 360-degree depicting both familiar unfamiliar, pleasant calming environments, accompanied by emotionally evocative, pleasant, soothing music. results demonstrated high levels immersion predominantly positive emotional responses, several reporting memory recall triggered VR stimulation. Statistical analysis revealed significant improvement in mood over time, regardless status, supporting effectiveness intervention. While there some side effects fatigue transient anxiety, experience was generally perceived as engaging meaningful. feasibility adds acceptability potential clinical utility provides justification future larger trials aimed at integration technologies into rehabilitation individuals different

Language: Английский

Citations

0
Methods for measuring interpersonal behavioral and neural synchrony during group music therapy for individuals with dementia and their caregivers: A case series study DOI
Joanna Culligan, Noor Tasnim, Patricia Winter

et al.

Journal of Alzheimer s Disease, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

Background: Alzheimer's disease and related dementias (ADRD) are neurodegenerative disorders that afflict 1 in 9 older adults. As pharmacological interventions for ADRD often ineffective cause rampant side effects, interest has increased finding adjunctive, non-pharmacological approaches. Music therapy may be especially beneficial individuals with their caregivers as music is a form of non-verbal communication. Objective: In this case series, we describe 12-week group program caregivers. Methods: Brain activity was recorded hyperscanning electroencephalography (EEG) during each session from the individual (n = 3), caregiver therapist 1). Video recordings allowed assessment movement behavior affective state responses. Results: This series had 66% retention 95.8% adherence rate. We success collecting behavioral neural data using 360-degree video capture combination EEG. us to analyze nonverbal communication metrics. After pre-processing, were clean able analyzed various metrics interest. Conclusions: A human-centered design approach can helpful implementing longitudinal, vulnerable population. team-science collective creative arts therapists, neuroscientists, dementia care experts, technologists, gerontology experts contributed conduction work. Future studies should examine effects on outcomes, it relates interpersonal synchrony.

Language: Английский

Citations

0