The psychophysiology of music-based interventions and the experience of pain

Frontiers in Psychology, Journal Year: 2024, Volume and Issue: 15

Published: May 10, 2024

In modern times there is increasing acceptance that music-based interventions are useful aids in the clinical treatment of a range neurological and psychiatric conditions, including helping to reduce perception pain. Indeed, belief music, whether listening or performing, can alter human pain experiences has long history, dating back ancient Greeks, its potential healing properties have been appreciated by indigenous cultures around world. The subjective experience acute chronic complex, influenced many intersecting physiological psychological factors, it therefore be expected impact music therapy on may vary from one situation another, person another. Where persists becomes chronic, aberrant central processing key feature associated with ongoing experience. Nonetheless, beneficial effects exposure relief reported across wide shown effective neonates, children adults. this comprehensive review we examine various neurochemical, factors underpin experience, potentially operate at levels – periphery, spinal cord, brainstem, limbic system multiple areas cerebral cortex. We discuss extent which these individually combination, influence how affects both quality intensity pain, noting remains controversy about respective roles diverse peripheral processes play Better understanding mechanisms underlie music’s together insights into should aid developing more synergistic approaches when combined treatments. ubiquitous nature also facilitates application therapeutic environment daily life, for individual social benefit.

Language: Английский

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Endogenous opiates and behavior: 2023

Peptides, Journal Year: 2024, Volume and Issue: 179, P. 171268 - 171268

Published: June 28, 2024

Language: Английский

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Effects of music advertised to support focus on mood and processing speed

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(2), P. e0316047 - e0316047

Published: Feb. 12, 2025

While music’s effects on emotion are widely appreciated, its cognition less understood. As mobile devices continue to afford new opportunities engage with music during work, it is important understand associated how we feel and perform. Capitalizing potential benefits, many commercial platforms advertise content specifically support attentional focus concentration. Although already in wide-spread use, the of such remain largely untested. In this online behavioral study, tested advertised “work flow” “deep focus” mood performance a cognitively demanding psychological test (the flanker task). We additionally included sample popular hit representing mainstream musical stimulation office noise typical background social working environment. Our findings show that, despite similar marketing, only work flow gave rise significant positively correlated improvements (i.e., faster responses over time, accuracy). Analyses objective perceived features indicate consistency “arousal-mood theory” cognitive impact provide insights into can be structured regulate general population.

Language: Английский

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From Perception to Pleasure

Oxford University Press eBooks, Journal Year: 2023, Volume and Issue: unknown

Published: Nov. 23, 2023

Abstract How does perception of abstract tonal patterns—music—lead to the pleasure we experience from these sounds? The answer presented in this book is that music arises interactions between cortical loops enable processing sound patterns and subcortical circuits responsible for reward valuation. auditory cortex its ventral-stream connections encode acoustical features their relationships, maintain them working memory, form internal representations statistical which predictions are made about how evolve time. Disruption pathway leads amusia. dorsal stream allows sensory-motor transformations, production, metrical representation, leading when events will occur. These predictive processes play a central role creating expectancies musical transmitted dopaminergic system, where hedonic responses generated according well an event fits with predictions. linked balance predictability surprise patterns. perceptual systems anhedonia. Engagement system also related movement vocal cues, social factors, preference, emotion regulation.

Language: Английский

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Pleasurable music activates cerebral µ-opioid receptors: a combined PET-fMRI study

European Journal of Nuclear Medicine and Molecular Imaging, Journal Year: 2025, Volume and Issue: unknown

Published: April 4, 2025

The μ-opioid receptor (MOR) system mediates incentive motivation and the hedonic component of primary rewards such as food sex. However, there is no direct in vivo evidence for involvement MOR pleasure derived from aesthetic music. METHODS: We measured availability with positron emission tomography (PET) agonist radioligand [11C]carfentanil high affinity MORs during listening pleasurable music neutral baseline condition. Haemodynamic responses associated dynamic ratings to control stimuli were using functional magnetic resonance imaging (fMRI). PET results revealed that increased binding several cortical subcortical regions, including ventral striatum orbitofrontal cortex, known contain "hedonic hotspots". nucleus accumbens condition was number chills, linking subjective experience striatal opioid release. Individual variation tone influenced pleasure-dependent haemodynamic regions interoceptive, sensorimotor, reward processing. These findings provide first neuroimaging modulates function. indicate governs complex addition biologically essential rewards.

Language: Английский

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Anticipatory and consummatory neural correlates of monetary and music rewarding stimuli

Brain and Cognition, Journal Year: 2024, Volume and Issue: 179, P. 106186 - 106186

Published: June 5, 2024

Most of the literature on neural bases human reward and punishment processing has used monetary gains losses, but less is known about neurophysiological mechanisms underlying anticipation consumption other types rewarding stimuli. In present study, EEG was recorded from 19 participants who completed a modified version Monetary Incentive Delay (MID) task. During task, cues providing information potential future outcomes were presented to participants. Then, they had respond rapidly target stimulus win money or listening pleasant music, avoid losing unpleasant music. Results revealed similar responses for music cues, with increased activity indicating compared losses. However, differences emerged in outcome phase between showed an interaction type cue Feedback Related Negativity Fb-P3 ERPs theta negative feedbacks. contrast, significant interactions activities. These findings suggest positive these two

Language: Английский

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State-dependent auditory-reward brain network connectivity predicts degree of pleasure to music

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 15, 2024

Abstract Music can evoke pleasurable and rewarding experiences. Past studies that examined task-related brain activity revealed individual differences in musical reward sensitivity traits, linked them to interactions between the auditory systems. However, state-dependent fluctuations spontaneous neural relation music-driven experiences have not been studied. Here, we used functional MRI (N=49) examine whether coupling of auditory-reward networks during a silent period immediately before music listening predict degree experience. We machine learning models showed connectivity networks, but others, could robustly subjective, physiological, neurobiological aspects strong chills. Specifically, right cortex-striatum/orbitofrontal connections predicted reported duration chills activation level NAcc insula, whereas auditory-amygdala connection was associated with psychophysiological arousal. Furthermore, predictive model derived from first sample individuals generalized an independent dataset using different samples. The current study reveals critical role sensory-reward pre-task state modulating subsequent

Language: Английский

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Pleasurable music activates cerebral μ-opioid receptors: A combined PET-fMRI study

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: April 14, 2024

Abstract The μ-opioid receptor (MOR) system mediates incentive motivation and the hedonic component of primary rewards such as food sex. However, there is no direct in vivo evidence for involvement MOR pleasure derived from aesthetic music. We measured activation with positron emission tomography (PET) agonist radioligand [ 11 C] carfentanil high affinity MORs during listening pleasurable music neutral baseline condition. Haemodynamic responses to were using functional magnetic resonance imaging (fMRI). PET results revealed that increased C]carfentanil binding several cortical subcortical regions, including ventral striatum orbitofrontal cortex, known contain “hedonic hotspots”. Individual variation tone influenced pleasure-dependent haemodynamic regions associated interoceptive, sensorimotor, reward processing. Our provide first-ever neuroimaging modulates indicate governs complex addition biologically salient rewards.

Language: Английский

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Endogenous mu-opioid modulation of social connection in humans: a systematic review and meta-analysis

Translational Psychiatry, Journal Year: 2024, Volume and Issue: 14(1)

Published: Sept. 17, 2024

Social bonding, essential for health and survival in all social species, depends on mu-opioid signalling non-human mammals. A growing neuroimaging psychopharmacology literature also implicates mu-opioids human connectedness. To determine the role of connectedness healthy humans, we conducted a preregistered ( https://osf.io/x5wmq ) multilevel random-effects meta-analysis randomised double-blind placebo-controlled opioid antagonist studies. We included data from 8 publications 2 unpublished projects, totalling 17 outcomes (N = 455) sourced final search Web Science, Scopus, PubMed EMBASE October 12, 2023, through community contributions. All studies used naltrexone (25-100 mg) to block system measured by self-report. Opioid antagonism slightly reduced feelings (Hedges' g [95% CI) -0.20] [-0.32, -0.07]. Results were highly consistent within between (I

Language: Английский

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Motivation and music interventions in adults: A systematic review

Neuropsychological Rehabilitation, Journal Year: 2023, Volume and Issue: 34(5), P. 649 - 678

Published: June 21, 2023

Music is increasingly used in a wide array of settings, from clinical recovery to sports or well-being interventions. Motivation related music often considered as possible working mechanism for facilitate these processes, however this has not previously been systematically evaluated. The current systematic review studies that involved (therapy) interventions, together with motivation-related measures such wanting practise, liking the musical activities, patient adherence an intervention. Our objective was examine whether increased motivation task performance and/or rehabilitation and turn better training outcomes. Seventy-nine met inclusion criteria, majority which (85%) indicated level compared without. Moreover, those where increased, other outcomes were improved most cases (90%). These results support notion underlying music-based but more robust evidence needed ascertain mechanisms are crucial increasing behavioural, cognitive, neurobiological point view, well how motivational relate factors effectiveness paradigms.

Language: Английский

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