Psychiatry and Clinical Neurosciences,
Journal Year:
2018,
Volume and Issue:
72(8), P. 602 - 610
Published: May 18, 2018
Alterations
of
cerebral
blood
flow
have
been
reported
in
studies
depression
treated
by
transcranial
magnetic
stimulation
(TMS).
However,
the
relation
between
these
changes
activity
during
and
effectiveness
TMS
is
not
known.
The
aim
this
study
was
to
determine
whether
frontal
volume
measured
as
hemoglobin
concentration
(fHbC)
are
correlated
with
clinical
outcomes
treatment.Fifteen
drug-resistant
patients
underwent
a
standard
treatment
regimen
left
dorsolateral
prefrontal
cortex.
We
recorded
fHbC
at
start
end
series
using
near-infrared
spectroscopy.
Symptom
severity
determined
Montgomery-Åsberg
Depression
Rating
Scale.At
series,
increased
majority
no
symptom
severity.
increase
negatively
Scale
score
positively
reduction.
Patients
showing
decreasing
response
experienced
less
improvement.These
results
suggest
that
maintenance
activation
course
related
depression.
Measurement
informative
use
TMS.
NeuroImage Clinical,
Journal Year:
2017,
Volume and Issue:
14, P. 648 - 655
Published: Jan. 1, 2017
Recent
studies
have
highlighted
the
clinical
usefulness
of
near-infrared
spectroscopy
(NIRS)
in
psychiatry.
However,
potential
effects
psychotropics
on
NIRS
signals
remain
unknown.We
conducted
a
systematic
chart
review
40
depressed
patients
who
underwent
scans
during
verbal
fluency
task
to
clarify
relationships
between
psychotropic
dosage
and
signals.
The
medications
was
calculated
using
defined
daily
dose
(DDD).
We
investigated
associations
DDD
oxygenated
hemoglobin
(oxy-Hb)
single
channel
levels.Retrospective
study
design
small
sample
size
are
main
limitations.Multiple
regression
analysis
revealed
that
one
right
temporoparietal
region
had
significant
association
with
antidepressant
controlling
for
age,
sex,
depression
severity,
antipsychotics
benzodiazepines.
Moreover,
high
doses
antidepressants
compared
low
doses,
group
comparisons.The
dose-dependent
impact
should
be
taken
into
account
when
interpreting
data.
Neurorehabilitation and neural repair,
Journal Year:
2018,
Volume and Issue:
32(11), P. 976 - 987
Published: Nov. 1, 2018
Background.
Aging
is
associated
with
declining
mobility,
which
negatively
affects
quality
of
life
and
incurs
substantial
economic
costs.
Techniques
to
maintain
safe
mobility
in
older
adults
are
therefore
essential.
Rhythmic
auditory
cueing
(RAC)
can
improve
walking
patterns
adults.
However,
the
neural
correlates
RAC,
how
they
influenced
by
repeated
exposure
their
relationships
gait
response,
cognitive
function,
depressive
symptoms
unclear.
Objectives.
This
study
aimed
investigate
effects
RAC
during
on
cortical
activation
relationship
between
RAC-related
changes
symptoms,
response.
Methods.
Seventeen
young
eighteen
walked
a
motorized
treadmill
for
5
minutes
(5
trials
alternating
30-second
blocks
usual
walking).
Changes
oxygenated
hemoglobin
(HbO
2
)
frontal
cortex
were
recorded
using
functional
near-infrared
spectroscopy.
Cognitive
domains
assessed
through
validated
tests.
A
triaxial
accelerometer
measured
parameters.
Results.
Gait
variability
decreased
prefrontal
HbO
levels
increased
cued
relative
walking.
Older
showed
greater
multiple
motor
regions
although
response
reduced
exposure.
In
adults,
lower
depression
scores,
higher
functioning,
linked
Conclusion.
These
findings
suggest
that
improves
achieved
activity
areas.
The
decline
indicates
adults’
ability
adapt
new
task.
