Latin American consensus on the treatment of melasma DOI Creative Commons
Jorge Ocampo‐Candiani,

Roberto Alas‐Carbajal,

Jorge F. Bonifaz‐Araujo

et al.

International Journal of Dermatology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 16, 2024

Abstract Melasma is a chronic, relapsing hyperpigmentation disorder that primarily affects photoexposed areas, occurring most frequently in adult women with darker skin phototypes. The primary factors contributing to its development include sun exposure, sex hormones (e.g., pregnancy), and genetic predisposition. highly prevalent Latin America, where many countries lie intertropical zones exhibit significant ethnic diversity because of centuries intermixing among Native Americans, Europeans, Sub‐Saharan Africans. Nine American experts formulated DELPHI‐based consensus develop valuable approach for treating melasma this diverse population. After establishing an accurate diagnosis, assessing the impact on quality life, determining disease severity, recommends mitigating known triggers promoting rigorous photoprotection. Active therapy should be tailored based individual characteristics pregnancy status, previous treatments, sensitivity). Treatment options topical depigmenting agents, systemic therapies, procedural interventions such as laser therapy, microneedling, chemical peels. Periodic reassessment treatment essential, strategies adjusted if targeted outcomes are not achieved. Once clinical remission attained, patients continue using agents maintain strict photoprotection measures prevent recurrence.

Language: Английский

An Update on New and Existing Treatments for the Management of Melasma DOI Creative Commons
Christian Gan,

Michelle Rodrigues

American Journal of Clinical Dermatology, Journal Year: 2024, Volume and Issue: 25(5), P. 717 - 733

Published: June 19, 2024

Melasma is a chronic, acquired disorder of focal hypermelanosis that carries significant psychosocial impact and challenging for both the patient treating practitioner to manage in medium long term. Multiple treatments have been explored, often combination given many aetiological factors involved its pathogenesis. Therapeutic discoveries treat melasma are topic literature include range modalities, with recent developments including updates on visible light photoprotection, non-hydroquinone depigmenting agents, oral tranexamic acid, chemical peels, laser energy-based device therapy melasma. It increasingly important yet remain up-to-date arsenal available find an efficacious well-tolerated option our patients.

Language: Английский

Citations

10
Characteristics of dermal vascularity in melasma and solar lentigo DOI Open Access
Yusuke Hara, Takako Shibata

Photodermatology Photoimmunology & Photomedicine, Journal Year: 2024, Volume and Issue: 40(2)

Published: Feb. 14, 2024

Abstract Background /Purpose Melasma and solar lentigo (SL) are major benign hyperpigmented lesions, both have been shown to involve the dermal vasculature. This review discusses current knowledge regarding clinical characteristics of vascularity in melasma SL, as well results relevant molecular biological investigations. Methods PubMed Google Scholar were searched December 2023 identify articles related melasma, vasculature these lesions. Results Vascular morphologies SL detected by histological non‐invasive methods, including modalities such optical coherence tomography. Biological studies indicated that factors secreted from vascular endothelial cells, stem cell factor endothelin‐1, can promote melanogenesis. With respect phototherapy, blood vessel‐targeting laser treatments expected provide long‐term suppression pigmentation, but this regimen is only effective when dilated capillaries visible. Conclusion In experimental investigations revealing contributions hyperpigmentation. More treatment may require identification hyperpigmentation subtypes. future, (including phototherapy) accumulate through reliable validated measurements.

Language: Английский

Citations

5
The Therapeutic and Preventive Effects of Light‐Emitting Diode (LED) for Post‐Inflammatory Erythema and Hyperpigmentation: A Pilot Study DOI Open Access
Yanjun Dan, Li Chen, Shanglin Jin

et al.

Photodermatology Photoimmunology & Photomedicine, Journal Year: 2025, Volume and Issue: 41(2)

Published: Feb. 3, 2025

ABSTRACT Background/Purpose Photobiomodulation (PBM) using light‐emitting diodes (LEDs) benefits tissue regeneration and wound healing. However, evidence regarding the efficacy of LED for post‐inflammatory erythema (PIE) hyperpigmentation (PIH) is limited. The aim this study was to explore effect medical (830 nm 590 nm) in prevention treatment PIE PIH. Methods vivo PIE/PIH model simplified pigmentation reaction after acute UVB exposure. 308 light (225 or 270 mJ/cm 2 ) induced on thigh ten healthy subjects. Every subject received therapeutic preventive irradiation ( n = 10 each group). 830 (60 J/cm LEDs (20 were irradiated, respectively. For irradiation, D1, irradiated D0, 1, 3, 6 8. 6, 8 D9. Erythema index (EI), melanin (MI), transdermal water loss (TEWL), C‐Cube photography measured during 10‐day follow‐up visits. Results ΔEI ΔMI group significantly lower than control (ΔEI: 9.30 vs. 11.52, p 0.027; ΔMI: 7.79 9.25, 0.026). No significant difference found between ∆MI > 0.05). both nm: 9.85 19.90, 0.001; 12.50 0.008). two groups Conclusions Both showed effects PIE, could effectively improve

Language: Английский

Citations

0
Clinical Efficacy of CGF Combined With Periodic Supramolecular Salicylic Acid in the Treatment of Chloasma DOI Creative Commons

Ge Su,

Qiang Fu, Xun Zhou

et al.

Journal of Cosmetic Dermatology, Journal Year: 2025, Volume and Issue: 24(4)

Published: March 26, 2025

ABSTRACT Objective To investigate the clinical efficacy of CGF combined with supramolecular salicylic acid cycle injection for melasma. Methods Twenty patients chloasma admitted to our hospital were selected and treated facial injection. After each injection, was given once. one treatment, severity melasma skin parameters before after treatment compared using modified Area Severity index (MASI) VISIA image analysis system, respectively. At same time, patients' self‐satisfaction investigated. Results The total effective rate in 95%. Compared scores spots, UV brown red areas, wrinkles, texture, pore porphyrins significantly increased treatment. MASI score reduced (4.70 ± 2.47 vs. 15.30 4.01, p < 0.001). results showed that satisfaction improvement 95.00%. Conclusion has an obvious effect on comprehensive overall aging patients, can effectively accelerate speed lesion repair pigment elimination, which is worthy promotion application.

Language: Английский

Citations

0
Phototherapy for pigmentary disorders DOI
Hee Young Kang

Photodermatology Photoimmunology & Photomedicine, Journal Year: 2024, Volume and Issue: 40(3)

Published: April 14, 2024

The author declares no conflicts of interest. Data sharing not applicable to this article as datasets were generated or analysed during the current study.

Language: Английский

Citations

0
Photobiomodulation Literature Watch November 2023 DOI
James D. Carroll

Photobiomodulation Photomedicine and Laser Surgery, Journal Year: 2024, Volume and Issue: 42(9), P. 604 - 607

Published: Aug. 10, 2024

Language: Английский

Citations

0
Latin American consensus on the treatment of melasma DOI Creative Commons
Jorge Ocampo‐Candiani,

Roberto Alas‐Carbajal,

Jorge F. Bonifaz‐Araujo

et al.

International Journal of Dermatology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 16, 2024

Abstract Melasma is a chronic, relapsing hyperpigmentation disorder that primarily affects photoexposed areas, occurring most frequently in adult women with darker skin phototypes. The primary factors contributing to its development include sun exposure, sex hormones (e.g., pregnancy), and genetic predisposition. highly prevalent Latin America, where many countries lie intertropical zones exhibit significant ethnic diversity because of centuries intermixing among Native Americans, Europeans, Sub‐Saharan Africans. Nine American experts formulated DELPHI‐based consensus develop valuable approach for treating melasma this diverse population. After establishing an accurate diagnosis, assessing the impact on quality life, determining disease severity, recommends mitigating known triggers promoting rigorous photoprotection. Active therapy should be tailored based individual characteristics pregnancy status, previous treatments, sensitivity). Treatment options topical depigmenting agents, systemic therapies, procedural interventions such as laser therapy, microneedling, chemical peels. Periodic reassessment treatment essential, strategies adjusted if targeted outcomes are not achieved. Once clinical remission attained, patients continue using agents maintain strict photoprotection measures prevent recurrence.

Language: Английский

Citations

0