Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112330 - 112330
Published: Nov. 1, 2024
Language: Английский
Periodontology 2000, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 8, 2025
Abstract To provide a comprehensive and updated mapping of observational studies assessing the relationship between periodontitis systemic diseases through bibliometric visual analysis. A search was conducted using Web Science database, covering period 1989 to 2024. The Medical Subject Headings (MeSH) from US National Library Medicine used categorize conditions, focusing on terms unrelated stomatognathic diseases. analysis included keyword co‐occurrence mapping, co‐authorship, bibliographic coupling, co‐citation Quality indicators such as silhouette score, modularity, centrality were considered assess network's quality. research strategy identified 6106 records, which 1519 met inclusion criteria. revealed that 46.73% literature topic published in last 5 years annual publication trend peaked 2023. Nutritional & Metabolic Diseases ( n = 398), Cardiovascular 335), Female Urogenital Pregnancy Complications 244), Musculoskeletal 182) most representative categories associated with periodontitis. co‐cited journals Journal Periodontology 1412), Clinical 1343), Dental Research 940), 2000 849). USA, China, Brazil, Sweden countries contributed number publications. present study growing evaluating association diseases, highlighting negative impact plethora conditions rising translational interest this relationship. With an aging population, is expected affect people coming decades, presenting significant challenges public health. Improved knowledge is, therefore, essential enable more care, preventive strategies, optimal oral health for patients
Language: Английский
Citations
4
Inflammation, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 27, 2025
Periodontitis is a chronic inflammatory disease characterized by inflammation of the periodontal soft tissues and loss alveolar bone. In oral environment, subgingival microorganisms salivary metabolites reflect host's health status. This study aimed to understand periodontitis severity progression rate analyzing microflora identify potential biomarkers. Fifty-three volunteers with stage II were graded using bone (%)/age index into two grades: 33 in grade A (< 0.25) 20 B (0.25–1.00). Using case–control study, simultaneously analyzed biomarkers associated periodontitis. The red complex, orange Campylobacter spp., uncultured Candidatus Saccharibacteria such as 5-Aminovaleric acid, N1-Acetylspermine showed significant positive correlation clinical parameters. Furthermore, we identified four differential (DL-Leucineamide, Dodecanedioic L-Tyrosine methyl ester Phenylpyruvic acid) that may serve for predicting progression. These results complex significantly correlated influenced changes metabolites. Additionally, indicating predominantly amino acid derivatives, confirming interactions between exacerbate development.
Language: Английский
Citations
0
Periodontology 2000, Journal Year: 2024, Volume and Issue: 95(1), P. 7 - 9
Published: June 1, 2024
Abstract Chronic inflammatory periodontal disease and its related condition, peri‐implant disease, are highly prevalent globally require accurate speedy diagnosis. The focus of this volume dedicated to diagnostics is cover modern enhancements in accuracy, simplicity speed. An international assortment experts has been tasked with reviewing defined areas current best practice as well innovation the field periodontitis peri‐implantitis diagnostics. Periodontitis irreversible, chronic, cumulative conditions propagated by bacteria host factors, which involve soft hard tissue changes, these changes measured diagnostic process. Clinically relevant modifications healthy state detected using clinical, radiological laboratory or point care testing, testing approaches critically reviewed at length state‐of‐the‐art resume
Language: Английский
Citations
3
Clinical Oral Investigations, Journal Year: 2024, Volume and Issue: 28(10)
Published: Sept. 13, 2024
This study aims to analyse the association between baseline microbial load of selected periodontopathogenic bacteria collected from gingival crevicular fluid (GCF) and primary outcome steps I II therapy.
Language: Английский
Citations
1
Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)
Published: Dec. 27, 2024
Type 2 diabetes mellitus (T2DM) is associated with cellular abnormalities, tissue and organ dysfunctions, periodontitis. This investigation examined the relationship between oral microbiome salivary biomarkers in T2DM patients or without cohort (35-80 years) included systemically healthy non-periodontitis (NP; n = 31), periodontitis (DWoP; 32) (DWP; 29). The [Operational Taxonomic Units (OTUs)] (16 s rRNA sequencing) targeted host (immunoassays) were assessed. We identified 47 OTUs that significantly different abundance NP samples any disease subset subgroups. most unique patterns observed DWP group. Differences genera/species also when stratified by extent of periodontal inflammation (i.e., generalized versus localized gingivitis/periodontitis). Salivary showed significant elevations MMP-8, MMP-9, resistin, IL-1β, IL-6, IFNα, BAFF (THFSR13b) comparing to analytes positive correlations specific members, predominantly patients. Odds ratio analyses reinforced a panel biologic markers (IL-6, MMP-8) bacteria (e.g., Bacteroidetes, Fusobacteria, Spirochaetes) discriminated severity this diabetic population.
Language: Английский
Citations
1
Oral Surgery Oral Medicine Oral Pathology and Oral Radiology, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
Citations
0
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(23), P. 12624 - 12624
Published: Nov. 25, 2024
Periodontitis leads to immunologically mediated loss of periodontium and, if untreated, can result in tooth loss. Periodontal diseases are the most prevalent world and have a very strong impact on patients' well-being general health. Their treatment generates enormous costs. Given above, precise, prompt, predictive diagnosis periodontal disease is paramount importance for clinicians. The aim study was summarize state-of-the-art knowledge molecular diagnostics utility its clinical application. There great need diagnostic tests that not only describe destruction has occurred tissues but also allow clinicians detect at subclinical level before changes occur. A test would enable follow course areas prone exacerbation could be used evaluate effectiveness ongoing therapies. Unfortunately, there no such method yet. hopeful prospect diagnostics. numerous studies biomarkers disease. Point-of-care emerging. possibilities processing large biological datasets (omics data). However, all above minor role overall single-patient process. Despite advances microbiological, molecular, genetic research, basis still examination enriched by evaluation radiological images.
Language: Английский
Citations
0
Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112330 - 112330
Published: Nov. 1, 2024
Language: Английский
Citations
0