Reduction of Streptococcus salivarius by Chlorella-Mediated Antimicrobial Photodynamic Therapy DOI Open Access
Mohammad Reza Karimi,

Navid Pourahmad,

Shima Afrasiabi

et al.

Journal of lasers in medical sciences, Journal Year: 2024, Volume and Issue: 15, P. e58 - e58

Published: Nov. 26, 2024

Introduction: Nowadays, antimicrobial photodynamic therapy (aPDT) has been introduced as one of the minimally invasive methods for disinfection surfaces dental implants. Being derived from seaweed, Chlorella used a photosensitizer in this study. This study aimed to investigate impacts aPDT with on rate reduction Streptococcus salivarius vitro. Methods: The minimum inhibitory concentration Chlorella, sublethal exposure 660 nm diode laser irradiation, and dose utilizing against S. were determined. Finally, CFU/mL value each plate was calculated. Then, Tukey HSD one-way ANOVA tests utilized comparison number colonies after interventions. Results: A 250 µg/mL at an irradiation time 3 minutes, identified salivarius. In contrast, application 4 minutes combination final 500 µg/mL, demonstrated significantly greater efficacy reducing compared other experimental groups (P<0.001). Conclusion: mediated (660 nm, minutes) significant effect count.

Language: Английский

Implant-supported full-arch fixed dental prostheses manufactured through a direct digital workflow using a calibrated splinting framework: A retrospective clinical study DOI

Filippo Rustichini,

Roldano Romolini,

Mika Salmi

et al.

Journal of Dentistry, Journal Year: 2025, Volume and Issue: unknown, P. 105605 - 105605

Published: Feb. 1, 2025

Language: Английский

Citations

2

The Role of Photodynamic Therapy Mediated by Natural Photosensitisers in the Management of Peri-Implantitis: A Systematic Review DOI Creative Commons

Aleksandra Warakomska,

Jakub Fiegler-Rudol,

Magdalena Kubizna

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(4), P. 443 - 443

Published: March 30, 2025

Background: Peri-implantitis, an inflammatory condition leading to progressive bone loss around dental implants, represents a significant challenge in modern implant dentistry. Conventional mechanical debridement and adjunctive antibiotics or antiseptics often fail fully eradicate complex biofilms may promote antibiotic resistance. Photodynamic therapy (PDT) mediated by natural photosensitizers (e.g., curcumin, riboflavin, 5-aminolevulinic acid) has emerged as potential strategy for peri-implantitis management due its targeted antimicrobial anti-inflammatory effects. Objectives: This systematic review aimed evaluate the efficacy, clinical outcomes, safety of PDT treatment identify optimal protocols regarding photosensitizer concentrations, light source parameters, application techniques. Methods: Following PRISMA 2020 guidelines, databases (PubMed/Medline, Embase, Scopus, Cochrane Library) were searched from 1 January 2015 3 2025 English-language publications. Studies assessing naturally based interventions vitro diseased surfaces included. Quality assessment used Revised Risk Bias tool (RoB 2) randomized controlled trials tailored nine-item framework studies. Eleven studies met inclusion criteria. Results: Despite heterogeneity methodologies, especially wavelengths, energy densities, formulations, most reported notable reductions bacterial viability, biofilm mass, indices (probing depth bleeding on probing). Curcumin riboflavin frequently demonstrated comparable efficacy standard disinfectants, while acid (5-ALA)-based also showed promising microbiological improvements. However, complete eradication was rarely achieved. Conclusions: Natural-photosensitizer-based appears be valuable adjunct peri-implantitis, enhancing microbial control outcomes. Standardization further well-designed with extended follow-up periods are warranted confirm long-term inform evidence-based guidelines.

Language: Английский

Citations

2

Introduction to the Diagnostics in Periodontology and Implant Dentistry issue DOI Creative Commons
Denis F. Kinane, Michael M. Bornstein

Periodontology 2000, Journal Year: 2024, Volume and Issue: 95(1), P. 7 - 9

Published: June 1, 2024

Abstract Chronic inflammatory periodontal disease and its related condition, peri‐implant disease, are highly prevalent globally require accurate speedy diagnosis. The focus of this volume dedicated to diagnostics is cover modern enhancements in accuracy, simplicity speed. An international assortment experts has been tasked with reviewing defined areas current best practice as well innovation the field periodontitis peri‐implantitis diagnostics. Periodontitis irreversible, chronic, cumulative conditions propagated by bacteria host factors, which involve soft hard tissue changes, these changes measured diagnostic process. Clinically relevant modifications healthy state detected using clinical, radiological laboratory or point care testing, testing approaches critically reviewed at length state‐of‐the‐art resume

Language: Английский

Citations

5

The Relationship Between Peri-Implant Marginal Bone Loss and Resonance Frequency Analysis DOI Creative Commons
Esteban Pérez-Pevida,

Iván Monteagudo-Villalobos,

David Chávarri‐Prado

et al.

Journal of Functional Biomaterials, Journal Year: 2025, Volume and Issue: 16(2), P. 71 - 71

Published: Feb. 18, 2025

Resonance frequency analysis (RFA) has been used as a diagnostic method to measure implant stability at all stages of healing. In addition evaluating the status peri-implant marginal bone, it can also indicate most appropriate time load implant. This in vitro study aimed evaluate efficacy RFA for detection bone loss (MBL). Forty bone-level Klockner Vega implants were placed polyurethane block with elastic properties similar those maxillary bone. The insertion torque and primary placement measured using an device. A circumferential defect was created by removing cortical portion each trephine. values again RFA. lower after creation defect, indicating statistically significant decrease stability. results tend show relationship between modifications

Language: Английский

Citations

0

Maxillary Sinus Grafting Complications: Diagnosis, Management, Patient Outcomes, and Role of Multidisciplinary Care DOI Open Access
Alberto Maria Saibene,

Stephen S. Wallace,

Riccardo Scaini

et al.

Clinical Implant Dentistry and Related Research, Journal Year: 2025, Volume and Issue: 27(2)

Published: March 25, 2025

Maxillary sinus grafting (MSG) is often crucial for successful dental implant placement in the atrophic maxilla. However, it carries risk of sinonasal complications, with outcomes frequently influenced by patient's health and subjective assessment surgeons. Thorough preoperative evaluation otolaryngologists vital to reduce these risks. This study emphasizes importance interdisciplinary collaboration managing complications following MSG. By highlighting role evaluations proposing a systematic approach, aims improve surgical planning optimize patient outcomes. Sinonasal after MSG can be classified into early delayed categories, each requiring distinct management approaches. Early such as infections graft migration, demand immediate attention, while issues, like osseointegration failure, pose longer term challenges. Accurate diagnosis difficult due overlap symptoms other conditions, necessitating comprehensive clinical evaluations, endoscopic findings, radiographic imaging. Collaboration between otolaryngology specialists essential, underscoring need multidisciplinary strategy complications. Managing post-MSG requires prompt combination medical interventions. detection treatment, supported structured are key improving Integrating otolaryngological expertise critical ensuring success procedures enhancing overall care.

Language: Английский

Citations

0

Dysregulation of the Immune System in Advanced Periimplantitis: Systemic Implications and Inflammatory Mechanisms—A Hematological and Immunological Study DOI Open Access
Michał Łobacz, Mansur Rahnama, Paulina Mertowska

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(7), P. 2453 - 2453

Published: April 3, 2025

Objectives: This study aimed to assess the systemic and local inflammatory responses in patients with periimplantitis, focusing on key immune markers clinical parameters. The further explores relationship between markers, indices, dysregulation, particularly regarding T-cell exhaustion inflammation. Methods: A cohort of classified into moderate advanced stages, was compared a control group healthy individuals dental implants. Clinical parameters, including plaque index (API), bleeding probing (BoP), pocket depth (PPD), peri-implant sulcus (PSI), were recorded. Hematological, immunological, biochemical analyses performed, focus cell populations (NK cells, T-cells, their PD-1 PD-L1). Results: Patients periimplantitis exhibited significantly higher indices (API, BoP, PSI, PPD) than group, most pronounced differences group. Hematological analysis revealed increased leukocyte neutrophil counts, whereas NK levels reduced. Immunological profiling indicated elevated PD-L1 expression suggesting dysregulation. Furthermore, strong correlations found PPD values marker levels, highlighting Conclusions: findings confirm that dysregulation plays central role progression. association alterations, emphasizes need for multifactorial diagnostic treatment approach. Integrating modulation strategies, assessments, lifestyle modifications, such as improved oral hygiene smoking cessation, could improve disease management reduce recurrence.

Language: Английский

Citations

0

Performance of artificial intelligence-based diagnosis and classification of peri-implantitis compared with periodontal surgeon assessment: a pilot study of panoramic radiograph analysis DOI
Jae‐Hong Lee, Yeon‐Tae Kim, Falk Schwendicke

et al.

Journal of Periodontal & Implant Science, Journal Year: 2025, Volume and Issue: 55

Published: Jan. 1, 2025

The aim of this study was to evaluate the diagnostic and classification performance a deep learning (DL) model for peri-implantitis-related bone defects using panoramic radiographs, focusing on defect morphology severity. A dataset comprising 1,075 radiographs from 426 patients with peri-implantitis analyzed. total 2,250 implant sites were annotated categorized based (intraosseous [class I], supracrestal/horizontal II], or combined III]) severity (slight, moderate, severe). ensemble-based YOLOv8 DL trained 80% dataset, remaining 20% reserved testing. Performance assessed metrics, including accuracy, precision, recall, F1 score. accuracy also compared that 2 board-certified periodontal surgeons. achieved an overall 85.33%, significantly outperforming surgeons, who exhibited mean 75.6%. performed especially well slight class II defects, precision recall values 100% 98%, respectively. In contrast, surgeons demonstrated higher in severe cases, particularly defects. enables reliable accurate detection It outperformed demonstrating its potential as valuable second-opinion tool support clinical decision-making. Future research should focus expanding datasets incorporating multimodal imaging.

Language: Английский

Citations

0

Effectiveness of Erythritol-Based Air Polishing and Ultrasonic Instrumentation with PEEK Inserts in Peri-Implant Maintenance: A Randomized Clinical Trial Including Different Prosthetic Materials DOI Creative Commons
Carolina Maiorani, Andrea Butera, Carlos Pérez Martı́nez

et al.

Dentistry Journal, Journal Year: 2025, Volume and Issue: 13(6), P. 235 - 235

Published: May 26, 2025

Background: Peri-implant diseases, including mucositis and peri-implantitis, pose a challenge to implant dentistry require effective maintenance protocols. Professional biofilm removal is essential for peri-implant health, but the optimal decontamination method remains controversial. Methods: This randomized clinical trial compared erythritol-based air polishing ultrasonic instruments with PEEK (polyetheretherketone) inserts in maintenance, also regarding different prosthetic materials. A total of 120 patients implant-supported feldspar ceramic, zirconia, or lithium disilicate crowns were randomly assigned one two methods. Clinical parameters, probing pocket depth (PPD), bleeding on (BOP), plaque index (PI), evaluated at baseline (T0), six months (T1), twelve (T2). Statistical analysis was performed using Friedman’s test repeated measures, followed by Dunn’s post hoc test. Subgroup conducted based material. Results: Both treatment modalities led statistically significant reductions parameters over 12 months. In erythritol group, PPD decreased 21.62%, BOP 86.62%, PI 90.74%. 14.86%, 78.69%, 64.86% (p < 0.05 all). No differences observed between groups > 0.05). revealed similar improvements across all crown materials, suggesting that efficacy not influenced type Conclusions: instrumentation are comparable health. As outcomes independent composition, choice should be tailored patient-specific needs conditions. Future studies longer follow-up recommended evaluate long-term impact tissue stability explore role materials more comprehensively.

Language: Английский

Citations

0

Dental Evaluation DOI
Riccardo Scaini, Andrea Berzaghi, Alberto Maria Saibene

et al.

Otolaryngologic Clinics of North America, Journal Year: 2024, Volume and Issue: 57(6), P. 1083 - 1097

Published: Aug. 30, 2024

Language: Английский

Citations

2

Clinical outcomes and supragingival microbiota analysis around dental implants and teeth in patients with a history of periodontitis: a preliminary study of 6 months follow-up DOI

Nicholas Choo Wee Sim,

Anis Rageh Al‐Maleki, Eshamsul Sulaiman

et al.

Clinical Oral Investigations, Journal Year: 2024, Volume and Issue: 28(10)

Published: Sept. 16, 2024

Language: Английский

Citations

1