Frontiers in Marine Science,
Journal Year:
2022,
Volume and Issue:
9
Published: Sept. 23, 2022
Immunostimulants
are
becoming
one
of
the
most
effective
models
for
healthy
and
sustainable
development
against
vibriosis,
which
is
a
serious
threat
to
global
aquaculture
industry.
This
study
evaluated
effects
different
concentrations
Ganoderma
lucidum
polysaccharides
(GLPs)
on
immunomodulation
disease
resistance
pearl
gentian
groupers.
The
relative
percent
survival
groupers
challenged
with
Vibrio
harveyi
ZJ0603
by
intraperitoneal
injection
reached
53.3,
60,
70,
73.3%
in
GLPs2,
GLPs4,
GLPs6,
GLPs8
groups,
respectively,
significantly
higher
than
that
33.3%
control
group.
Meanwhile,
expression
levels
immune-relative
genes,
including
IgM
,
MHC-Iα
MHC2
IL-1β
TNF-α
were
upregulated
liver,
spleen,
head
kidney,
thymus
within
28
days
after
GLP
injection.
total
serum
protein
activities
catalase,
superoxide
dismutase,
lysozymes
all
groups
compared
those
control.
Moreover,
optimal
immunity
effect
was
observed
an
GLPs
at
6
or
8
mg/ml.
results
demonstrate
immunostimulant,
enhancing
both
specific
non-specific
as
well
grouper.
Fish & Shellfish Immunology,
Journal Year:
2023,
Volume and Issue:
137, P. 108773 - 108773
Published: April 25, 2023
Misuse
and
overuse
of
antibiotics
in
aquaculture
has
proven
to
be
an
unsustainable
practice
leading
increased
bacterial
resistance.
An
alternative
strategy
involves
the
inclusion
immunostimulants
fish
diets,
especially
fungal
herbal
compounds
already
authorized
for
human
consumption,
hence
without
environmental
or
public
health
concerns.
In
this
study,
we
used
a
holistic
cross-disciplinary
pipeline
assess
immunostimulatory
properties
two
fungi:
Trametes
versicolor
Ganoderma
lucidum;
one
supplement,
capsaicin
form
Espelette
pepper
(Capsicum
annuum),
combination
these
additives
on
rainbow
trout
(Oncorhynchus
mykiss).
We
investigated
impact
diet
supplementation
7
weeks
survival,
growth
performance,
cellular,
humoral,
molecular
immune
parameters,
as
well
intestinal
microbial
composition
fish.
Uptake
influenced
expression
related
genes,
generating
inflammatory
response.
Significant
differences
were
detected
spleen-tlr2
gene
expression.
Supplementation
with
correlated
structural
changes
microbiota
enhanced
overall
diversity.
Results
demonstrated
that
different
treatments
had
no
adverse
effect
performance
suggesting
safety
feed
at
tested
concentrations.
While
mechanisms
multifactorial
interactions
remain
unclear,
study
provides
insights
not
only
regard
nutrition
compounds,
but
also
how
combined
gut
approach
can
shed
light
efficacy
immunostimulant
potential
commercial
supplements.
BMC Microbiology,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: Sept. 9, 2024
The
quest
for
candidate
probiotics
and
prebiotics
to
develop
novel
synbiotics
sustainable
profitable
fish
farming
remains
a
major
focus
various
stakeholders.
In
this
study,
we
examined
the
effects
of
combining
two
fungal
probiotics,
Saccharomyces
cerevisiae
Aspergillus
niger
with
extracts
Jerusalem
artichoke
white
button
mushroom
synbiotic
formulation
improve
growth
health
status
zebrafish
(Danio
rerio).
An
initial
in
vitro
study
determined
most
effective
combination,
which
was
then
tested
60-day
vivo
nutritional
trial
using
(80
±
1.0
mg)
as
model
animal.
Four
experimental
diets
were
prepared:
control
diet
(basal
diet),
prebiotic
100%
selected
extract,
probiotic
10
Journal of Basic Microbiology,
Journal Year:
2024,
Volume and Issue:
64(8)
Published: May 22, 2024
Abstract
Global
interest
in
mushroom
farming
techniques
has
grown
the
last
few
years.
Despite
not
making
up
a
large
amount
of
human
diet
at
moment,
nutritional
worth
mushrooms
prompted
their
usage.
The
three
main
segments
global
industry
are
wild,
culinary
(edible),
and
medicinal
mushrooms.
quality
food
that
provide
can
be
utilized
to
build
agricultural
ecosystems
more
sustainable
for
increasing
productivity
enhancing
effectiveness
resource
This
is
mostly
because
recycling
biomass
remains
from
crop
production.
Culinary‐medicinal
becoming
important
nutrient
density,
dietary
value,
health
advantages.
Given
its
many
bioactive
components,
which
include
polysaccharides,
proteins,
vitamins,
minerals,
fiber,
secondary
metabolites,
have
been
extensively
as
foods.
These
exhibit
pharmacological
activities
possess
prebiotic
antibacterial
capabilities.
review
provides
information
on
latest
advancements
cultivation
mushrooms,
particularly
with
nontraditional
substrates,
potential
therapeutic
uses.
Furthermore,
some
newest
developments
difficulties
production
explored.
Animals,
Journal Year:
2023,
Volume and Issue:
13(11), P. 1805 - 1805
Published: May 30, 2023
Decreasing
low
molecular
weight
can
improve
the
digestibility
and
availability
of
ingredients
such
as
sodium
alginate.
This
study
aimed
to
test
four
dosages
alginate
(LMWSA)
(0%:
Control,
0.05%:
0.5
LMWSA,
0.10%:
1.0
0.2%:
2.0
LMWSA)
in
whiteleg
shrimp
(Litopenaeus
vannamei)
(3.88
±
0.25
g)
for
eight
weeks.
After
finishing
trial,
were
exposed
cadmium
(1
mg/L)
48
h.
While
feed
conversion
ratio
(FCR)
improved
fed
dietary
LMWSA
(p
<
0.05),
there
was
no
significant
difference
growth
among
treatments.
The
results
showed
a
linear
relation
between
level
FCR,
glutathione
S-transferase
(GST)
before;
malondialdehyde
(MDA),
(GSH),
GST,
alanine
transaminase
(ALT)
after
stress
0.05).
MDA,
ALT,
aspartate
(AST)
contents
changed
but
not
group.
survival
rate
(85.23%)
(80.20%)
treatments
significantly
higher
than
Control
(62.05%).
negatively
correlated
with
GST
introducing
them
potential
biomarkers
exposure
shrimp.
Accordingly,
treatment
had
best
performance
abovementioned
parameters.
As
observed,
supplementing
more
levels
reach
plateau
is
recommended.
Prospects in Pharmaceutical Sciences,
Journal Year:
2023,
Volume and Issue:
21(4), P. 33 - 39
Published: Nov. 9, 2023
Mushrooms,
regarded
as
a
significant
component
of
the
ecosystem,
are
utilised
by
individuals
for
various
purposes.
The
present
study
aimed
to
investigate
biological
activities
Agrocybe
praecox
(Pers.)
Fayod,
commonly
referred
Spring
Fieldcap
mushroom.
ethanol
extract
mushroom
was
obtained
with
Soxhlet
apparatus.
Subsequently,
quantification
total
antioxidant,
oxidant,
and
oxidative
stress
index
conducted
utilizing
Rel
Assay
kits.
phenolic
content
determined
using
Folin-Ciocalteu
reagent.
agar
dilution
method
employed
assess
antimicrobial
activity
extract.
antiproliferative
compound
assessed
A549
lung
cancer
cells.
Elemental
levels
fungus
were
measured
wet
digestion
method.
findings
revealed
that
elements
fell
within
range
reported
in
existing
literature.
In
addition,
it
antioxidant
value
2.97±0.08,
oxidant
7.63±0.16,
0.26±0.01,
49.7±3.0
mg/g.
It
found
be
effective
against
microorganisms
at
concentrations
between
50-200
µg/mL.
Furthermore,
ascertained
this
exhibited
activity,
degree
being
contingent
upon
concentration
Consequently,
exhibits
potential
an
antimicrobial,
anticancer
agent.
Journal of Fungi,
Journal Year:
2024,
Volume and Issue:
10(10), P. 711 - 711
Published: Oct. 11, 2024
Ensuring
sustainability
has
increasingly
become
a
significant
concern
not
only
in
aquaculture
but
the
general
agrifood
sector.
Therefore,
it
is
imperative
to
investigate
pathways
feed
substitutes/best
practices
enhance
sustainability.
The
application
of
fungi
provides
innovative
methods
and
productivity
aquaculture.
Fungi
play
numerous
roles
aquaculture,
including
growth,
immunity
enhancement
disease
resistance.
They
also
role
bioremediation
waste
bioflocculation.
improves
suitability
utilization
terrestrial
plant
ingredients
by
reducing
fibre
fractions
anti-nutritional
factors
increasing
nutrients
mineral
contents
ingredients.
are
good
flotation
agents
can
buoyancy
aquafeed.
Pigments
from
colouration
fish
fillets,
making
them
more
attractive
consumers.
This
paper,
via
relevant
literature,
explores
multifaceted
emphasizing
their
potential
transform
through
environmentally
friendly
sustainable
techniques.
effectiveness
enhancing
nutrient
availability
influenced
duration
fermentation
dosage
administered,
which
may
differ
for
various
ingredients,
difficult
most
farmers
apply
approximately.
effective
each
ingredient
should
be
investigated.