Cancers,
Journal Year:
2020,
Volume and Issue:
12(12), P. 3684 - 3684
Published: Dec. 8, 2020
Living
with
metastatic
cancer,
or
metavivorship,
differs
from
cancer
survivorship
and
has
changed
as
novel
treatments
have
increased
survival
time.
The
purpose
of
this
narrative
review
is
to
describe
factors
that
impact
challenges
in
metavivorship
within
a
conceptual
framework
guide
future
research.
This
focuses
on
the
specific
outcomes
progressive
disease,
time,
symptoms,
distress,
financial
toxicity,
quality
life.
We
predisposing,
precipitating,
perpetuating
(3P)
model
metavivorship.
Understanding
biological,
psychological,
social
3P
contribute
development
maintenance
provides
roadmap
for
Implications
include
prevention
by
targeting
predisposing
factors,
management
precipitating
after
onset
treatment
reduce
symptoms
improve
life
during
chronic
phase
can
be
accomplished
through
biopsychosocial
screening
efforts,
monitoring
patient-reported
outcomes,
education
communication
interventions,
interdisciplinary
symptom
management,
advance
care
planning,
behavioral
interventions
cultivate
psychological
resilience.
Nanomaterials,
Journal Year:
2019,
Volume and Issue:
9(4), P. 638 - 638
Published: April 19, 2019
Many
therapeutically
active
molecules
are
non-soluble
in
aqueous
systems,
chemically
and
biologically
fragile
or
present
severe
side
effects.
Lipid-based
nanoparticle
(LBNP)
systems
represent
one
of
the
most
promising
colloidal
carriers
for
bioactive
organic
molecules.
Their
current
application
oncology
has
revolutionized
cancer
treatment
by
improving
antitumor
activity
several
chemotherapeutic
agents.
LBNPs
advantages
include
high
temporal
thermal
stability,
loading
capacity,
ease
preparation,
low
production
costs,
large-scale
industrial
since
they
can
be
prepared
from
natural
sources.
Moreover,
association
agents
with
lipid
nanoparticles
reduces
therapeutic
dose
toxicity,
decreases
drug
resistance
increases
levels
tumor
tissue
decreasing
them
healthy
tissue.
have
been
extensively
assayed
vitro
therapy
but
also
vivo,
results
some
clinical
trials.
This
review
summarizes
types
that
developed
recent
years
main
when
applied
treatment,
including
essential
assays
patients.
BMC Psychiatry,
Journal Year:
2020,
Volume and Issue:
20(1)
Published: July 6, 2020
Young
women
diagnosed
with
breast
cancer
face
challenges
that
interfere
their
entire
life
psychological
and
physical
effects.We
employed
a
qualitative
exploratory
descriptive
design,
recruited
twelve
participants
through
purposive
snowball
sampling
methods
to
conduct
12
individual
interviews.
A
reputable
review
board
in
Ghana;
Noguchi
Memorial
Institute
for
Medical
Research,
gave
ethical
clearance
data
collection.
Data
were
transcribed
verbatim
analysed
using
thematic
content
analysis.Three
themes
emerged
from
the
data;
effects
of
cancer,
treatment
on
body
image,
emotional
diagnosis
treatment.
The
negative
incapacitated
most
limited
activities
daily
living.
Some
experienced
severe
bodily
weakness
stayed
indoors
days.
Most
felt
they
looked
unattractive
because
have
had
mastectomy
done,
used
pieces
rags
handkerchiefs
as
prostheses.
Those
who
hair
loss
chemotherapy
different
kinds
wigs
cover
baldness.
Almost
all
cried,
depressed,
became
emotionally
unstable
when
told
diagnosis.
denied
diagnoses
displaced
anger
healthcare
personnel.
few
them
brought
disgrace
families
is
perceived,
disgraceful
disease.Young
require
interventions
support
personnel
families.
International Journal of Molecular Sciences,
Journal Year:
2019,
Volume and Issue:
20(11), P. 2780 - 2780
Published: June 6, 2019
Sleep
is
essential
for
health.
Indeed,
poor
sleep
consistently
linked
to
the
development
of
systemic
disease,
including
depression,
metabolic
syndrome,
and
cognitive
impairments.
Further
evidence
has
accumulated
suggesting
role
in
cancer
initiation
progression
(primarily
breast
cancer).
patients
with
survivors
frequently
experience
sleep,
manifesting
as
insomnia,
circadian
misalignment,
hypersomnia,
somnolence
hot
flushes,
nightmares.
These
problems
are
associated
a
reduction
patients’
quality
life
increased
mortality.
Due
heterogeneity
among
cancers,
treatment
regimens,
patient
populations
lifestyle
factors,
etiology
cancer-induced
disruption
largely
unknown.
Here,
we
discuss
recent
advances
understanding
pathways
linking
brain
how
this
leads
altered
patterns.
We
describe
conceptual
framework
where
tumors
disrupt
normal
homeostatic
processes,
resulting
aberrant
changes
physiology
behavior
that
detrimental
Finally,
knowledge
can
be
leveraged
develop
novel
therapeutic
approaches
cancer-associated
disruption,
special
emphasis
on
host-tumor
interactions.
Nutrition and Cancer,
Journal Year:
2019,
Volume and Issue:
71(1), P. 21 - 40
Published: Jan. 2, 2019
Cancer-related
fatigue
(CRF)
is
a
debilitating
syndrome
that
persists
for
many
cancer
survivors
years
after
treatment.
Symptoms
include
early
and
persistent
fatigue,
functional
decline,
depression,
cognitive
difficulties.
Inflammation,
assessed
using
pro-inflammatory
biomarkers,
increased
in
with
treatments
are
often
aimed
at
reducing
inflammation.
Additionally,
its
treatment
lead
to
nutritional
complications,
changes
body
composition,
deficiencies
potentially
weaken
the
survivor
impact
CRF.
We
conducted
qualitative
review
of
clinical
trials
interventions
preventing
treating
Further
studies
were
examined
used
address
inflammation
due
dearth
nutrition
research
directly
related
Dietary
intake
prior
to,
during,
appears
affect
levels.
Increased
protein
may
help
preserve
lean
mass
composition.
patterns
reduce
inflammation,
such
as
Mediterranean
diet
other
plant-based
diets,
appear
tolerable
fatigue.
Supplementation
ginseng,
ginger,
or
probiotics
improve
survivors'
energy
Nutritional
interventions,
alone
combination
should
be
considered
therapy
survivors.
Breast Cancer,
Journal Year:
2022,
Volume and Issue:
29(3), P. 402 - 418
Published: March 12, 2022
Abstract
Background
This
systematic
review
aims
to
identify
the
effects
of
exercise
interventions
in
patients
with
breast
cancer
(BCP)
and
survivors
(BCS)
on
selected
variables
physical
fitness.
Methods
A
comprehensive
literature
search
was
conducted
using
Medline
Scopus.
Randomized
controlled
trials
isolated
BCP
BCS
women
(<
5
years
from
therapy
completion)
were
included.
The
risk
bias
(RoB)
assessment
Cochrane
RoB-2-tool.
Variables
regarding
cardiorespiratory
fitness
(CRF),
strength
(ST),
fatigue
(F)
health-related
quality
life
(HRQoL)
discussed.
Results
Of
336
studies
initially
identified,
22
met
all
inclusion
criteria
deemed
eligible.
RoB
indicated
that
had
predominantly
“some
concerns”
or
“low
RoB”,
only
3
presenting
a
“high
RoB”.
mean
duration
frequency
19
weeks
sessions/week,
performed
at
moderate
intensity
(65%
V
O
2
max
66%
1RM,
for
aerobic
resistance-training
interventions,
respectively).
Conclusions
Exercise
seem
be
valuable
strategy
avoid
decline
CRF,
ST,
F
HRQoL.
Conversely,
improved
function
among
is
observed
same
variables.
Resistance
training
combined
provide
most
encouraging
variations
outcomes.
PROSPERO
registration
ID
CRD42021237917.
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 8, 2024
Wearable
health
devices
are
becoming
vital
in
chronic
disease
management
because
they
offer
real-time
monitoring
and
personalized
care.
This
review
explores
their
effectiveness
challenges
across
medical
fields,
including
cardiology,
respiratory
health,
neurology,
endocrinology,
orthopedics,
oncology,
mental
health.
A
thorough
literature
search
identified
studies
focusing
on
wearable
devices'
impact
patient
outcomes.
In
wearables
have
proven
effective
for
hypertension,
detecting
arrhythmias,
aiding
cardiac
rehabilitation.
these
enhance
asthma
continuous
of
critical
parameters.
Neurological
applications
include
seizure
detection
Parkinson's
management,
with
showing
promising
results
improving
technology
advances
thyroid
dysfunction
monitoring,
fertility
tracking,
diabetes
management.
Orthopedic
improved
postsurgical
recovery
rehabilitation,
while
help
early
complication
oncology.
Mental
benefits
anxiety
detection,
post-traumatic
stress
disorder
reduction
through
biofeedback.
conclusion,
transformative
potential
managing
illnesses
by
enhancing
engagement.
Despite
significant
improvements
adherence
outcomes,
data
accuracy
privacy
persist.
However,
ongoing
innovation
collaboration,
we
can
all
be
part
the
solution
to
maximize
technologies
healthcare.
Cancer Cell International,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: April 1, 2025
Cancer
is
a
rising
issue
worldwide,
and
numerous
studies
have
focused
on
understanding
the
underlying
reasons
for
its
occurrence
finding
proper
ways
to
defeat
it.
By
applying
technological
advances,
researchers
are
continuously
uncovering
updating
treatments
in
cancer
therapy.
Their
vast
functions
regulation
of
cell
growth
proliferation
their
significant
role
progression
diseases,
including
cancer.
This
review
provides
comprehensive
analysis
ncRNAs
breast
cancer,
focusing
long
non-coding
RNAs
such
as
HOTAIR,
MALAT1,
NEAT1,
well
microRNAs
miR-21,
miR-221/222,
miR-155.
These
pivotal
regulating
proliferation,
metastasis,
drug
resistance,
apoptosis.
Additionally,
we
discuss
experimental
approaches
that
useful
studying
them
highlight
advantages
challenges
each
method.
We
then
explain
results
these
clinical
trials
offer
insights
future
by
discussing
major
existing
gaps.
On
basis
an
extensive
number
studies,
this
valuable
into
potential
Key
findings
show
even
though
undeniable
there
still
complications
associated
with
therapeutic
use.
Moreover,
absence
sufficient
experiments
regarding
application
mouse
models,
which
area
work
on.
emphasizing
crucial
ncRNAs,
underscores
need
innovative
further
explore
