Dietary B vitamins and glioma: A case–control study based on Chinese population DOI Creative Commons

Weichunbai Zhang,

Jing Jiang,

Xun Kang

et al.

Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 10

Published: March 2, 2023

Background Dietary antioxidants have long been thought to be likely prevent the development of gliomas. Previous studies reported vitamin A, C, and E protective effects against B vitamins, one main vitamins in diet, are closely related human health, but association with gliomas has rarely reported. Objective This study aimed evaluate relationship between five glioma. Methods In this Chinese population-based case–control study, 506 glioma cases matched (age sex) controls were included. The dietary intake participants was assessed using a valid 111-item food frequency questionnaire. calculated based on participants’ information from logistic regression model used examine glioma, restriction cubic spline evaluated dose–response two. Results After adjusting for confounding factors, thiamine (OR = 0.09, 95%CI: 0.05–0.20), riboflavin 0.12, 0.06–0.25), nicotinic acid 0.24, 0.12–0.47), folate 0.07, 0.03–0.15) biotin 0.14, 0.07–0.30) highest tertile associated significantly decreased risk compared lowest tertile. results different pathological types grades different. restricted function showed significant relationships When exceeded specific intake, did not change. Conclusion Our suggests that higher thiamine, riboflavin, acid, consistent among populations. future, prospective should conducted better validate

Language: Английский

Scientific opinion on the tolerable upper intake level for vitamin B6 DOI Creative Commons
Dominique Turck, Torsten Bohn,

Jacqueline Castenmiller

et al.

EFSA Journal, Journal Year: 2023, Volume and Issue: 21(5)

Published: May 1, 2023

Abstract Following a request from the European Commission, EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver scientific opinion tolerable upper intake level (UL) for vitamin B6. Systematic reviews of literature were conducted by contractor. The relationship between excess B6 intakes development peripheral neuropathy is well established critical effect which UL based. A lowest-observed-effect-level (LOAEL) could not be based human data. reference point (RP) 50 mg/day identified case–control study, supported data case reports vigilance An uncertainty factor (UF) 4 applied RP account inverse dose time onset symptoms limited available. latter covers uncertainties as that would represent LOAEL. This leads 12.5 mg/day. From subchronic study in Beagle dogs, LOAEL mg/kg body weight (bw) per day can identified. Using an UF 300, default bw 70 kg, 11.7 calculated. midpoint range these two ULs rounding down, 12 adults (including pregnant lactating women). infants children are derived using allometric scaling: 2.2–2.5 (4–11 months), 3.2–4.5 (1–6 years), 6.1–10.7 (7–17 years). Based available data, EU populations unlikely exceed ULs, except regular users food supplements containing high doses

Language: Английский

Citations

20
Examination of Primary and Secondary Metabolites Associated with a Plant-Based Diet and Their Impact on Human Health DOI Creative Commons

Miray Simsek,

Kristin Whitney

Foods, Journal Year: 2024, Volume and Issue: 13(7), P. 1020 - 1020

Published: March 27, 2024

The consumption of plant-based diets has become a burgeoning trend, and they are increasingly consumed globally owing to their substantial energy intensity dietetic advantages. Plants possess numerous bioactive components that have been recognized exhibit manifold health-promoting assets. Comprehension the synthesis these primary secondary metabolites by plants method action against several chronic illnesses is significant requirement for understanding benefits human health disease prevention. Furthermore, association biologically active complexes with plants, humans, disease, medicine, underlying mechanisms unexplored. Therefore, this review portrays various derived from plant sources associated traits mechanisms. This paper predominantly assembles proposed plant-derived compounds, postulating valuable evidence aimed at perceiving forthcoming approaches, including selection potent formulating functional effective disorders. meticulous could perhaps provide basis advanced preemptive therapeutic potential promoting health. Hence, delivery opens possibilities purchasers approach lucrative practice as remedy, produce novel products, access new marketplaces.

Language: Английский

Citations

6
Unveiling of dietary and gut-microbiota derived B vitamins: Metabolism patterns and their synergistic functions in gut-brain homeostasis DOI

Qi Zhan,

Rui Wang, Kiran Thakur

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2022, Volume and Issue: 64(13), P. 4046 - 4058

Published: Oct. 22, 2022

Nutrition-gut cross-talk holds a vital position in sustaining intestinal function, and micronutrient metabolism has emerged as the foremost metabolic pathway to preserve gut homeostasis. Among micronutrients, B vitamins have evolved prior DNA/RNA are known for their roles major evolutionary transitions extant organisms. Despite universal requirement critical role, not all three domains of life endowed with natural ability

Language: Английский

Citations

19
Harnessing enzyme cofactors and plant metabolism: an essential partnership DOI
Paula da Fonseca‐Pereira,

Rita de Cássia Monteiro‐Batista,

Wagner L. Araújo

et al.

The Plant Journal, Journal Year: 2023, Volume and Issue: 114(5), P. 1014 - 1036

Published: March 2, 2023

SUMMARY Cofactors are fundamental to the catalytic activity of enzymes. Additionally, because plants a critical source several cofactors (i.e., including their vitamin precursors) within context human nutrition, there have been studies aiming understand metabolism coenzymes and vitamins in detail. For example, compelling evidence has brought forth regarding role plants; specifically, it is becoming increasingly clear that an adequate supply directly affects development, metabolism, stress responses. Here, we review state‐of‐the‐art knowledge on significance precursors with regard general plant physiology discuss emerging functions attributed them. Furthermore, how our understanding complex relationship between can be used for crop improvement.

Language: Английский

Citations

11
Functional foods and immune support: strengthening the body’s defense DOI
Gitanjali S. Deokar,

Pooja Shinde,

Sanjay J. Kshirsagar

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 199 - 232

Published: Jan. 1, 2025

Language: Английский

Citations

0
Biological, dietetic and pharmacological properties of vitamin B9 DOI Creative Commons
Tomáš Siatka, Marek Máťuš, Monika Moravcová

et al.

npj Science of Food, Journal Year: 2025, Volume and Issue: 9(1)

Published: March 13, 2025

Abstract Humans must obtain vitamin B 9 (folate) from plant-based diet. The sources as well the effect of food processing are discussed in detail. Industrial production, fortification and biofortification, kinetics, physiological role humans described. As folate deficiency leads to several pathological states, current opinions toward prevention through discussed. Claimed risks increased intake mentioned analytical ways for measurement folate.

Language: Английский

Citations

0
Melatonin-mediated adaptation of spinach (Spinacia oleracea L.) in acidic soil DOI
Md. Kamrul Hasan,

Md Abdullah Al-Hasib Imon,

Israt Jahan

et al.

Plant Physiology and Biochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 109816 - 109816

Published: March 1, 2025

Language: Английский

Citations

0
Multi-omic profiling reveals green manuring with maize enhances fruit quality of strawberry via the microbiome–plant–metabolite axis DOI

Huijing Fu,

Chenyu Sun,

Xiaolong Shu

et al.

Plant and Soil, Journal Year: 2025, Volume and Issue: unknown

Published: April 20, 2025

Language: Английский

Citations

0
Association of serum water-soluble vitamin exposures with the risk of metabolic syndrome: results from NHANES 2003-2006 DOI Creative Commons

Xun Pei,

Junjie Yao,

Simiao Ran

et al.

Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14

Published: May 12, 2023

Introduction Existing evidence suggests an association between certain vitamins and metabolic syndrome (MetS), but few epidemiological studies have focused on the effects of multivitamin co-exposure MetS. This study aims to investigate associations individual or multiple water-soluble (i.e., vitamin C (VC), B9 (VB9), B12 (VB12)) with MetS, as well dose-response relationships among them. Methods A cross-sectional was conducted by employing National Health Examination Surveys (NHANESs) 2003-2006. Multivariate-adjusted logistic regression models were used explore serum risk MetS its components, including waist circumference, triglyceride, high-density lipoprotein, blood pressure, fasting plasma glucose. Restricted cubic splines performed The quantile g-computation method adopted components. Results total 8983 subjects involved in study, whom 1443 diagnosed groups had a higher proportion participants age ≥60 years, BMI ≥30 kg/m 2 , insufficient physical activity. Compared lowest quartile, third (OR=0.67, 95% CI: 0.48, 0.94) highest quartiles (OR=0.52, 95%CI: 0.35, 0.76) VC associated lower risk. showed negative VC, VB9 VB12, Regarding glucose, while lipoprotein (HDL). Co-exposure VB9, VB12 significantly inversely ORs (95% CI) 0.81 (0.74, 0.89) 0.84 (0.78, 0.90) conditional marginal structural models, respectively. Furthermore, we found that negatively circumference positively HDL. Conclusion revealed high

Language: Английский

Citations

10
Simultaneous Identification of Vitamins B1, B3, B5, and B6 by an Engineered Nanopore DOI

Yusheng Ouyang,

Kefan Wang, Wendong Jia

et al.

Nano Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 13, 2024

Vitamin Bs, a group of water-soluble compounds, are essential nutrients for almost all living organisms. However, due to their structural heterogeneity, rapid and simultaneous analysis multiple vitamin Bs is still challenging. In this paper, it discovered that hetero-octameric

Language: Английский

Citations

3