Frontiers in Genetics,
Journal Year:
2023,
Volume and Issue:
14
Published: Aug. 9, 2023
Exercise
genetics/genomics
is
a
growing
research
discipline
comprising
several
Strengths
and
Opportunities
but
also
deals
with
Weaknesses
Threats.
This
“systematic
SWOT
overview
of
non-systematic
reviews”
(sSWOT)
aimed
to
identify
the
Strengths,
Weaknesses,
Opportunities,
Threats
linked
exercise
genetics/genomics.
A
systematic
search
was
conducted
in
Medline
Embase
databases
for
reviews
provide
comprehensive
current
literature/research
area.
The
extracted
data
thematically
analyzed,
coded,
categorized
into
clusters.
In
45
included
five
nine
six
three
were
identified.
cluster
“advances
technology”,
“empirical
evidence”,
“growing
discipline”,
“establishment
consortia”,
“acceptance/accessibility
genetic
testing”.
“low
quality”,
“complexity
exercise-related
traits”,
generalizability”,
“high
costs”,
“genotype
scores”,
“reporting
bias”,
“invasive
methods”,
“research
progress”,
“causality”.
comprised
“precision
exercise”,
“omics”,
“multicenter
studies”,
as
well
“genetic
testing”
“commercial”-,
“screening”-,
“anti-doping”
detection
tool.
related
“ethical
issues”,
“direct-to-consumer
testing
companies”,
“gene
doping”.
present
state
art
sport
indicates
field
great
potential,
while
drawing
attention
necessity
additional
advancement
methodological
ethical
guidance
mitigate
recognized
substantiate
capability
make
significant
contributions
performance
wellbeing
athletes.
Frontiers in Sports and Active Living,
Journal Year:
2024,
Volume and Issue:
5
Published: Jan. 4, 2024
Introduction
The
present
study
investigated
the
role
of
training
intensity
in
dose–response
relationship
between
endurance
and
cardiorespiratory
fitness
(CRF).
hypothesis
was
that
beginners
would
benefit
from
an
increase
after
initial
phase,
even
if
energy
expenditure
not
altered.
For
this
purpose,
26
weeks
continuous
moderate
(control
group,
CON)
compared
to
with
gradually
increasing
(intervention
INC)
but
constant
expenditure.
Methods
Thirty-one
healthy,
untrained
subjects
(13
men,
18
women;
46
±
8
years;
body
mass
index
25.4
3.3
kg
m
−2
;
maximum
oxygen
uptake,
VO
2max
34
4
ml
min
−1
)
trained
for
10
[3
days/week
50
min/session
at
55%
heart
rate
reserve
(HR
)]
before
allocation
one
two
groups.
A
minimization
technique
used
ensure
homogeneous
While
group
CON
continued
16
weeks,
INC
70%
HR
thereafter
participated
a
×
program
(high-intensity
interval
training,
HIIT)
weeks.
Constant
ensured
by
indirect
calorimetry
corresponding
adjustment
volume.
Treadmill
tests
were
performed
baseline
10,
18,
Results
showed
improved
(3.4
2.7
significantly
greater
degree
than
(0.4
2.9
(
P
=
0.020).
In
addition,
exhibited
V
max
(1.7
0.7
km
h
(1.0
0.5
0.001).
reduction
resting
larger
(7
bpm)
(2
6
mean
submaximal
exercise
test
reduced
(5
bpm;
0.007)
(8
7
0.001),
without
significant
interaction
time
point.
Conclusion
Increasing
leads
adaptations
CRF
continuing
intensity,
increased
After
moderate-
higher-intensity
domain,
energy-matched
HIIT
elicited
further
fitness.
Thus,
plays
crucial
healthy
individuals.
Clinical
Trial
Registration
https://www.drks.de/DRKS00031445
,
identifier
DRKS00031445.
Cardiology Research,
Journal Year:
2024,
Volume and Issue:
15(1), P. 18 - 28
Published: Feb. 1, 2024
Background:
Supervised
exercise
training
decreases
total
and
cardiac
mortality
increases
quality
of
life
heart
failure
with
reduced
ejection
fraction
(HFrEF)
patients.
However,
response
to
is
variable
from
one
patient
another
factors
responsible
for
a
positive
remain
unclear.
The
aims
the
study
were
compare
hemodynamic
changes
after
an
program
in
responders
(R)
versus
non-responders
(NR)
HFrEF
patients,
different
discriminators
used
assess
training.
Methods:
Seventy-six
patients
(86%
males,
57
±
12
years)
completed
4
weeks.
Patients
underwent
cardiopulmonary
testing
(CPET)
on
cycle
ergometer
before
Cardiac
hemodynamics
measured
by
impedance
cardiography
during
CPET.
R
NR
groups
classified
using
median
change
peak
oxygen
uptake
(VO
2peak
).
Results:
There
statistically
significant
differences
VO
(+35%
vs.
-1%,
P
<
0.0001)
peaks
ventilation
(+30%
+2%,
0.0001),
output
(CO
)
(+25%
+4%,
0.01),
systolic
blood
pressure
(+12%
0.05),
diastolic
(+9%
0.05)
rate
(+8%
+1%,
0.01)
between
program.
was
best
discriminator
(receiver
operating
characteristic
(ROC)
area
under
curve
(AUC)
=
0.83,
followed
CO
(ROC
AUC
0.77,
0.0001).
Conclusion:
Responders
showed
improvements
parameters.
These
results
pave
way
other
studies
determine
how
individualization
programs
parameters
potentially
linked
better
status.
Cardiol
Res.
2024;15(1):18-28
doi:
https://doi.org/10.14740/cr1591
Research
on
physical
activity
and
health,
including
planned
structured
forms
such
as
acute
chronic
exercise,
has
focused
understanding
potential
dose-response
relationships.Traditionally,
the
variables
of
(i)
Frequency,
(ii)
Intensity,
(iii)
Time,
(iv)
Type
(known
FITT
principle)
have
been
used
to
operationalize
dose
activity.In
this
article,
we
describe
limitations
propose
that
it
should
be
complemented
by
underappreciated
variable
density,
which
defines
temporal
distribution
stimuli
within
a
single
bout
or
between
successive
bouts
relative
time
spent
resting
(e.g.,
in
napping/sleeping
sedentary
behaviors).Using
field
brain
health
an
example,
discuss
challenges
opportunities
for
further
research
use
density
improve
our
doseresponse
relationships
health-related
outcomes.
European Journal of Applied Physiology,
Journal Year:
2024,
Volume and Issue:
124(9), P. 2799 - 2807
Published: April 29, 2024
Heart
rate
(HR)
response
is
likely
to
vary
in
people
with
Parkinson's
disease
(PD),
particularly
for
those
chronotropic
incompetence
(CI).
This
study
explores
the
impact
of
CI
on
HR
and
metabolic
responses
during
cardiopulmonary
exercise
test
(CPET)
PD,
its
implications
intensity
prescription.
Frontiers in Genetics,
Journal Year:
2023,
Volume and Issue:
14
Published: Aug. 9, 2023
Exercise
genetics/genomics
is
a
growing
research
discipline
comprising
several
Strengths
and
Opportunities
but
also
deals
with
Weaknesses
Threats.
This
“systematic
SWOT
overview
of
non-systematic
reviews”
(sSWOT)
aimed
to
identify
the
Strengths,
Weaknesses,
Opportunities,
Threats
linked
exercise
genetics/genomics.
A
systematic
search
was
conducted
in
Medline
Embase
databases
for
reviews
provide
comprehensive
current
literature/research
area.
The
extracted
data
thematically
analyzed,
coded,
categorized
into
clusters.
In
45
included
five
nine
six
three
were
identified.
cluster
“advances
technology”,
“empirical
evidence”,
“growing
discipline”,
“establishment
consortia”,
“acceptance/accessibility
genetic
testing”.
“low
quality”,
“complexity
exercise-related
traits”,
generalizability”,
“high
costs”,
“genotype
scores”,
“reporting
bias”,
“invasive
methods”,
“research
progress”,
“causality”.
comprised
“precision
exercise”,
“omics”,
“multicenter
studies”,
as
well
“genetic
testing”
“commercial”-,
“screening”-,
“anti-doping”
detection
tool.
related
“ethical
issues”,
“direct-to-consumer
testing
companies”,
“gene
doping”.
present
state
art
sport
indicates
field
great
potential,
while
drawing
attention
necessity
additional
advancement
methodological
ethical
guidance
mitigate
recognized
substantiate
capability
make
significant
contributions
performance
wellbeing
athletes.