A Breathable, Passive‐Cooling, Non‐Inflammatory, and Biodegradable Aerogel Electronic Skin for Wearable Physical‐Electrophysiological‐Chemical Analysis DOI Open Access
Yangzhi Zhu, Reihaneh Haghniaz,

Martin C. Hartel

et al.

Advanced Materials, Journal Year: 2022, Volume and Issue: 35(10)

Published: Dec. 28, 2022

Abstract Real‐time monitoring of human health can be significantly improved by designing novel electronic skin (E‐skin) platforms that mimic the characteristics and sensitivity skin. A high‐quality E‐skin platform simultaneously monitor multiple physiological metabolic biomarkers without introducing discomfort or irritation is an unmet medical need. Conventional E‐skins are either monofunctional made from elastomeric films do not include key synergistic features natural skin, such as multi‐sensing, breathability, thermal management capabilities in a single patch. Herein, biocompatible biodegradable patch based on flexible gelatin methacryloyl aerogel (FGA) for non‐invasive continuous interest engineered demonstrated. Taking advantage cryogenic temperature treatment slow polymerization, FGA fabricated with highly interconnected porous structure displays good flexibility, passive‐cooling capabilities, ultra‐lightweight properties make it comfortable to wear long periods time. It also provides numerous permeable capillary channels thermal‐moisture transfer, ensuring its excellent breathability. Therefore, FGA‐based body temperature, hydration, biopotentials via electrophysiological sensors detect glucose, lactate, alcohol levels electrochemical sensors. This work offers previously unexplored materials strategy next‐generation superior practicality.

Language: Английский

End-to-end design of wearable sensors DOI Open Access
H. Ceren Ates, Peter Q. Nguyen, Laura Gonzalez‐Macia

et al.

Nature Reviews Materials, Journal Year: 2022, Volume and Issue: 7(11), P. 887 - 907

Published: July 22, 2022

Language: Английский

Citations

723

Wearable Pressure Sensors for Pulse Wave Monitoring DOI

Keyu Meng,

Xiao Xiao, Wenxin Wei

et al.

Advanced Materials, Journal Year: 2022, Volume and Issue: 34(21)

Published: Jan. 19, 2022

Abstract Cardiovascular diseases remain the leading cause of death worldwide. The rapid development flexible sensing technologies and wearable pressure sensors have attracted keen research interest been widely used for long‐term real‐time cardiovascular status monitoring. Owing to compelling characteristics, including light weight, wearing comfort, high sensitivity pulse pressures, physiological waveforms can be precisely continuously monitored by health Herein, an overview human wave monitoring is presented, with a focus on transduction mechanism, microengineering structures, related applications in condition assessment. conceptualizations methods acquisition pathological information system are outlined. biomechanics arterial waves working mechanism various sensors, triboelectric, piezoelectric, magnetoelastic, piezoresistive, capacitive, optical also subject systematic debate. Exemple measurement based structured devices then summarized. Finally, discussion opportunities challenges that face, as well their potential intelligent personalized healthcare given conclusion.

Language: Английский

Citations

618

Supramolecular Adhesive Hydrogels for Tissue Engineering Applications DOI
Yüe Zhao, Shanliang Song, Xiangzhong Ren

et al.

Chemical Reviews, Journal Year: 2022, Volume and Issue: 122(6), P. 5604 - 5640

Published: Jan. 13, 2022

Tissue engineering is a promising and revolutionary strategy to treat patients who suffer the loss or failure of an organ tissue, with aim restore dysfunctional tissues enhance life expectancy. Supramolecular adhesive hydrogels are emerging as appealing materials for tissue applications owing their favorable attributes such tailorable structure, inherent flexibility, excellent biocompatibility, near-physiological environment, dynamic mechanical strength, particularly attractive self-adhesiveness. In this review, key design principles various supramolecular strategies construct comprehensively summarized. Thereafter, recent research progress regarding applications, including primarily dermal repair, muscle bone neural vascular oral corneal cardiac fetal membrane hepatic gastric systematically highlighted. Finally, scientific challenges remaining opportunities underlined show full picture hydrogels. This review expected offer comparative views critical insights inspire more advanced studies on pave way different fields even beyond applications.

Language: Английский

Citations

452

Soft wearable devices for deep-tissue sensing DOI
Muyang Lin, Hongjie Hu, Sai Zhou

et al.

Nature Reviews Materials, Journal Year: 2022, Volume and Issue: 7(11), P. 850 - 869

Published: March 14, 2022

Language: Английский

Citations

205

Flexible Accelerated‐Wound‐Healing Antibacterial MXene‐Based Epidermic Sensor for Intelligent Wearable Human‐Machine Interaction DOI
Mingkun Li, Yunfei Zhang,

Lishuyi Lian

et al.

Advanced Functional Materials, Journal Year: 2022, Volume and Issue: 32(47)

Published: Sept. 17, 2022

Abstract Flexible epidermic sensors made from conductive hydrogels are holding bright potential in personalized healthcare, multifunctional electronic skins, and human‐machine interfaces. However, it is still a great challenge to simultaneously realize hydrogel‐based with reliable self‐healing ability remarkable sensing performances high‐performance healthcare (especially electrophysiological signals) for wearable interaction, as well accelerated wound healing subsequent medical treatment together. Herein, flexible healable sensor assembled the facilely prepared antibacterial MXene hydrogel efficiently sensitively interaction. The as‐prepared possesses enhanced mechanical performance, outstanding capability, injectability, facile degradability, excellent biocompatibility, robust ability, which capable of being into monitor human movements rehabilitation training, detect tiny signals diagnosis cardiovascular‐ muscle‐related diseases, be employed In addition, can utilized treat infection effectively accelerate healing. Thus, sheds light on preparing integration personal health smart interaction next‐generation artificial skins.

Language: Английский

Citations

204

Electronic skin as wireless human-machine interfaces for robotic VR DOI Creative Commons
Yiming Liu, Chun Ki Yiu,

Zhen Song

et al.

Science Advances, Journal Year: 2022, Volume and Issue: 8(2)

Published: Jan. 14, 2022

The coronavirus pandemic has highlighted the importance of developing intelligent robotics to prevent infectious disease spread. Human-machine interfaces (HMIs) give a chance interactions between users and robotics, which play significant role in teleoperating robotics. Conventional HMIs are based on bulky, rigid, expensive machines, mainly focus robots/machines control, but lack adequate feedbacks users, limit their applications conducting complicated tasks. Therefore, closed-loop with both accurate sensing feedback functions is extremely important. Here, we present HMI system skin-integrated electronics, whose electronics compliantly interface whole body for wireless motion capturing haptic via Bluetooth, Wireless Fidelity (Wi-Fi), Internet. integration visual VR together into robotic demonstrates great potentials noncontact collection bio samples, nursing patients many others.

Language: Английский

Citations

202

Ultrathin Hydrogel Films toward Breathable Skin‐Integrated Electronics DOI Creative Commons
Simin Cheng, Zirui Lou, Lan Zhang

et al.

Advanced Materials, Journal Year: 2022, Volume and Issue: 35(1)

Published: Oct. 21, 2022

On-skin electronics that offer revolutionary capabilities in personalized diagnosis, therapeutics, and human-machine interfaces require seamless integration between the skin electronics. A common question remains whether an ideal interface can be introduced to directly bridge thin-film with soft skin, allowing breathe freely skin-integrated function stably. Here, ever-thinnest hydrogel is reported compliant glyphic lines subtle minutiae on without forming air gaps, produced by a facile cold-lamination method. The hydrogels exhibit high water-vapor permeability, nearly unimpeded transepidermal water loss free breathing of underneath. Hydrogel-interfaced flexible (opto)electronics causing irritation or accelerated device performance deterioration are demonstrated. long-term applicability recorded for over one week. With combined features extreme mechanical compliance, biocompatibility, ultrathin promotes general

Language: Английский

Citations

173

Soft Bioelectronics Based on Nanomaterials DOI Creative Commons
Kyoung Won Cho, Sung‐Hyuk Sunwoo, Yongseok Joseph Hong

et al.

Chemical Reviews, Journal Year: 2021, Volume and Issue: 122(5), P. 5068 - 5143

Published: Dec. 28, 2021

Recent advances in nanostructured materials and unconventional device designs have transformed the bioelectronics from a rigid bulky form into soft ultrathin brought enormous advantages to bioelectronics. For example, mechanical deformability of thus its conformal contact onto curved organs such as brain, heart, skin allowed researchers measure high-quality biosignals, deliver real-time feedback treatments, lower long-term side-effects vivo. Here, we review various materials, fabrication methods, strategies for flexible stretchable electronics, especially focusing on biointegrated electronics using nanomaterials their composites. First, summarize top-down material processing bottom-up synthesis methods nanomaterials. Next, discuss state-of-the-art technologies intrinsically nanocomposites composed incorporated elastomers or hydrogels. We also briefly design Then individual components bioelectronics, biosensing, data storage, display, therapeutic stimulation, power supply devices, are introduced. Afterward, representative application examples described. A brief summary with discussion remaining challenges concludes review.

Language: Английский

Citations

153

Highly-integrated, miniaturized, stretchable electronic systems based on stacked multilayer network materials DOI Creative Commons
Honglie Song, Guoquan Luo,

Ziyao Ji

et al.

Science Advances, Journal Year: 2022, Volume and Issue: 8(11)

Published: March 16, 2022

Elastic stretchability and function density represent two key figures of merits for stretchable inorganic electronics. Various design strategies have been reported to provide both high levels density, but the densities are mostly below 80%. While stacked device layout can overcome this limitation, soft elastomers used in previous studies could highly restrict deformation interconnects. Here, we introduce multilayer network materials as a general platform incorporate individual components interconnects, without posing any essential constraint their deformations. Quantitative analyses show substantial enhancement (e.g., by ~7.5 times) elastic serpentine interconnects compared that based on elastomers. The proposed strategy allows demonstration miniaturized electronic system (11 mm 10 mm), with moderate (~20%) an unprecedented areal coverage (~110%), which serve compass display, somatosensory mouse, physiological-signal monitor.

Language: Английский

Citations

153

Transparent Electronics for Wearable Electronics Application DOI Creative Commons
Daeyeon Won,

Junhyuk Bang,

Seok Hwan Choi

et al.

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(16), P. 9982 - 10078

Published: Aug. 5, 2023

Recent advancements in wearable electronics offer seamless integration with the human body for extracting various biophysical and biochemical information real-time health monitoring, clinical diagnostics, augmented reality. Enormous efforts have been dedicated to imparting stretchability/flexibility softness electronic devices through materials science structural modifications that enable stable comfortable of these curvilinear soft body. However, optical properties are still early stages consideration. By incorporating transparency, visual from interfacing biological systems can be preserved utilized comprehensive diagnosis image analysis techniques. Additionally, transparency provides imperceptibility, alleviating reluctance wear device on exposed skin. This review discusses recent advancement transparent a way includes materials, processing, devices, applications. Materials discussed regarding their characteristics, synthesis, engineering strategies property enhancements. We also examine bridging techniques Building blocks systems, including sensors, energy actuators, displays, mechanisms performances. Lastly, we summarize potential applications conclude remaining challenges prospects.

Language: Английский

Citations

142