Evidence for domain-general arousal from semantic and neuroimaging meta-analyses reconciles opposing views on arousal DOI Creative Commons
Magdalena Sabat, Charles de Dampierre, Catherine Tallon‐Baudry

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2025, Volume and Issue: 122(6)

Published: Feb. 3, 2025

Arousal refers to changes in brain-body state underpinning motivated behavior but lacks a proper definition and taxonomy. Neuroscience psychology textbooks offer surprisingly different views on what arousal is, from global brain-wide modulation of neuronal activity multidimensional construct, with specific patterns tuned given situation. The huge number scientific articles mentioning (~50,000) highlights the importance concept also explains why such vast literature has never been systematically reviewed so far. Here, we leverage tools natural language processing probe nature data-driven, comprehensive manner. We show that comes seven varieties: cognitive, emotional, physiological, sexual, related stress disorders, sleep, or sleep disorders. then ask whether domain-general exists at cortical level, run meta-analyses brain imaging reveal all varieties arousal, except disorders for lack data, converge onto network composed presupplementary motor area left right dorsal anterior insula. More precisely, find dysgranular insular 7 (Jülich atlas), region highest convergence across is specifically associated arousal. might trigger reorganization large-scale networks-a mechanism-resulting context-specific configuration-in line view. Future taxonomies refining alignment between concepts data should include as central component.

Language: Английский

Gradients of Brain Organization: Smooth Sailing from Methods Development to User Community DOI
Jessica Royer, Casey Paquola, Sofie L. Valk

et al.

Neuroinformatics, Journal Year: 2024, Volume and Issue: unknown

Published: April 3, 2024

Language: Английский

Citations

10
Brain states as wave-like motifs DOI
Maya Foster, Dustin Scheinost

Trends in Cognitive Sciences, Journal Year: 2024, Volume and Issue: 28(6), P. 492 - 503

Published: April 5, 2024

Language: Английский

Citations

10
Time-varying functional connectivity predicts fluctuations in sustained attention in a serial tapping task DOI
Dolly T. Seeburger, Nan Xu, Marcus Ma

et al.

Cognitive Affective & Behavioral Neuroscience, Journal Year: 2024, Volume and Issue: 24(1), P. 111 - 125

Published: Jan. 22, 2024

Language: Английский

Citations

9
Symptom-based depression subtypes: brain dynamic specificity and its association with gene expression profiles DOI Creative Commons
Qunjun Liang, Zhifeng Zhou, Shengli Chen

et al.

Translational Psychiatry, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 28, 2025

At least 227 combinations of symptoms meet the criteria for Major Depressive Disorder (MDD). However, in clinical practice, patients consistently present a regular rather than random manner, and neural basis underlying MDD subtypes remains unclear. To help clarify basis, with were clustered by symptom to investigate underpinning each subtype using functional resonance imaging (fMRI). Four symptom-based identified latent profile analysis according scales. Subsequently, brain dynamics evaluated fMRI, dysregulations attention limbic network observed among subtypes. Correlation between was then assessed via canonical correlation (CCA). The brain-symptom higher when (r = 0.77 0.92) compared entire group 0.5). loading weight CCA showed that transmodal networks contributed most characterized typical depression symptoms, whereas unimodal anxiety insomnia. Finally, gene expression model, along its biological encoding process, performed postmortem atlas revealed distinct enrichments different These findings highlight clusters have specific correlates, providing insights into depression's heterogeneous diagnosis precision medicine opportunities.

Language: Английский

Citations

1
Evidence for domain-general arousal from semantic and neuroimaging meta-analyses reconciles opposing views on arousal DOI Creative Commons
Magdalena Sabat, Charles de Dampierre, Catherine Tallon‐Baudry

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2025, Volume and Issue: 122(6)

Published: Feb. 3, 2025

Arousal refers to changes in brain-body state underpinning motivated behavior but lacks a proper definition and taxonomy. Neuroscience psychology textbooks offer surprisingly different views on what arousal is, from global brain-wide modulation of neuronal activity multidimensional construct, with specific patterns tuned given situation. The huge number scientific articles mentioning (~50,000) highlights the importance concept also explains why such vast literature has never been systematically reviewed so far. Here, we leverage tools natural language processing probe nature data-driven, comprehensive manner. We show that comes seven varieties: cognitive, emotional, physiological, sexual, related stress disorders, sleep, or sleep disorders. then ask whether domain-general exists at cortical level, run meta-analyses brain imaging reveal all varieties arousal, except disorders for lack data, converge onto network composed presupplementary motor area left right dorsal anterior insula. More precisely, find dysgranular insular 7 (Jülich atlas), region highest convergence across is specifically associated arousal. might trigger reorganization large-scale networks-a mechanism-resulting context-specific configuration-in line view. Future taxonomies refining alignment between concepts data should include as central component.

Language: Английский

Citations

1