PROTAC targeted protein degraders: the past is prologue

Nature Reviews Drug Discovery, Journal Year: 2022, Volume and Issue: 21(3), P. 181 - 200

Published: Jan. 18, 2022

Language: Английский

---

RNA in cancer

Nature reviews. Cancer, Journal Year: 2020, Volume and Issue: 21(1), P. 22 - 36

Published: Oct. 20, 2020

Language: Английский

---

Targeted protein degradation: expanding the toolbox

Nature Reviews Drug Discovery, Journal Year: 2019, Volume and Issue: 18(12), P. 949 - 963

Published: Oct. 30, 2019

Language: Английский

---

Roles and mechanisms of alternative splicing in cancer — implications for care

Nature Reviews Clinical Oncology, Journal Year: 2020, Volume and Issue: 17(8), P. 457 - 474

Published: April 17, 2020

Language: Английский

---

Ubiquitylation at the crossroads of development and disease

Nature Reviews Molecular Cell Biology, Journal Year: 2017, Volume and Issue: 19(1), P. 59 - 70

Published: Sept. 20, 2017

Language: Английский

---

Advancing targeted protein degradation for cancer therapy

Nature reviews. Cancer, Journal Year: 2021, Volume and Issue: 21(10), P. 638 - 654

Published: June 15, 2021

Language: Английский

---

A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader

Cell chemical biology, Journal Year: 2017, Volume and Issue: 25(1), P. 88 - 99.e6

Published: Nov. 9, 2017

Language: Английский

---

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

Nature Chemical Biology, Journal Year: 2019, Volume and Issue: 15(7), P. 737 - 746

Published: June 17, 2019

Language: Английский

---

Development of targeted protein degradation therapeutics

Nature Chemical Biology, Journal Year: 2019, Volume and Issue: 15(10), P. 937 - 944

Published: Sept. 16, 2019

Language: Английский

---

PROTACs: An Emerging Therapeutic Modality in Precision Medicine

Cell chemical biology, Journal Year: 2020, Volume and Issue: 27(8), P. 998 - 1014

Published: Aug. 1, 2020

Language: Английский

---