Nature Microbiology,
Journal Year:
2023,
Volume and Issue:
8(7), P. 1348 - 1361
Published: June 15, 2023
Although
the
interaction
between
prokaryotic
and
eukaryotic
microorganisms
is
crucial
for
functioning
of
ecosystems,
information
about
processes
driving
microbial
interactions
within
communities
remains
scarce.
Here
we
show
that
arginine-derived
polyketides
(arginoketides)
produced
by
Streptomyces
species
mediate
cross-kingdom
with
fungi
genera
Aspergillus
Penicillium,
trigger
production
natural
products.
Arginoketides
can
be
cyclic
or
linear,
a
prominent
example
azalomycin
F
iranensis,
which
induces
cryptic
orsellinic
acid
gene
cluster
in
nidulans.
Bacteria
synthesize
arginoketides
decode
respond
to
this
signal
were
co-isolated
from
same
soil
sample.
Genome
analyses
literature
search
indicate
arginoketide
producers
are
found
worldwide.
Because,
addition
their
direct
impact,
induce
secondary
wave
fungal
products,
they
probably
contribute
wider
structure
entire
communities.
Nucleic Acids Research,
Journal Year:
2023,
Volume and Issue:
51(W1), P. W310 - W318
Published: May 11, 2023
Abstract
Microbiome
studies
have
become
routine
in
biomedical,
agricultural
and
environmental
sciences
with
diverse
aims,
including
diversity
profiling,
functional
characterization,
translational
applications.
The
resulting
complex,
often
multi-omics
datasets
demand
powerful,
yet
user-friendly
bioinformatics
tools
to
reveal
key
patterns,
important
biomarkers,
potential
activities.
Here
we
introduce
MicrobiomeAnalyst
2.0
support
comprehensive
statistics,
visualization,
interpretation,
integrative
analysis
of
data
outputs
commonly
generated
from
microbiome
studies.
Compared
the
previous
version,
features
three
new
modules:
(i)
a
Raw
Data
Processing
module
for
amplicon
processing
taxonomy
annotation
that
connects
directly
Marker
Profiling
downstream
statistical
analysis;
(ii)
Metabolomics
help
dissect
associations
between
community
compositions
metabolic
activities
through
joint
paired
metabolomics
datasets;
(iii)
Statistical
Meta-Analysis
identify
consistent
signatures
by
integrating
across
multiple
Other
improvements
include
added
multi-factor
differential
interactive
visualizations
popular
graphical
outputs,
updated
methods
prediction
correlation
analysis,
expanded
taxon
set
libraries
based
on
latest
literature.
These
are
demonstrated
using
dataset
recent
type
1
diabetes
study.
is
freely
available
at
microbiomeanalyst.ca.
Advanced Materials,
Journal Year:
2022,
Volume and Issue:
34(26)
Published: March 4, 2022
Living
biological
systems,
ranging
from
single
cells
to
whole
organisms,
can
sense,
process
information,
and
actuate
in
response
changing
environmental
conditions.
Inspired
by
living
engineered
nonliving
matrices
are
brought
together,
which
gives
rise
the
technology
of
materials.
By
designing
functionalities
structures
matrices,
materials
be
created
detect
variability
surrounding
environment
adjust
their
functions
accordingly,
thereby
enabling
applications
health
monitoring,
disease
treatment,
remediation.
Hydrogels,
a
class
soft,
wet,
biocompatible
materials,
have
been
widely
used
as
for
cells,
leading
nascent
field
hydrogels.
Here,
interactions
between
hydrogel
described,
focusing
on
how
hydrogels
influence
cell
behaviors
affect
properties.
The
environments,
these
enable
versatile
applications,
also
discussed.
Finally,
current
challenges
facing
clinical
settings
highlighted.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Feb. 3, 2024
Abstract
Chronic
diabetic
wounds
are
at
lifelong
risk
of
developing
foot
ulcers
owing
to
severe
hypoxia,
excessive
reactive
oxygen
species
(ROS),
a
complex
inflammatory
microenvironment,
and
the
potential
for
bacterial
infection.
Here
we
develop
programmed
treatment
strategy
employing
live
Haematococcus
(HEA).
By
modulating
light
intensity,
HEA
can
be
perform
variety
functions,
such
as
antibacterial
activity,
supply,
ROS
scavenging,
immune
regulation,
suggesting
its
use
in
therapy.
Under
high
intensity
(658
nm,
0.5
W/cm
2
),
green
(GHEA)
with
efficient
photothermal
conversion
mediate
wound
surface
disinfection.
decreasing
0.1
photosynthetic
system
GHEA
continuously
produce
oxygen,
effectively
resolving
problems
hypoxia
promoting
vascular
regeneration.
Continuous
irradiation
induces
astaxanthin
(AST)
accumulation
cells,
resulting
gradual
transformation
from
red
hue
(RHEA).
RHEA
scavenges
excess
ROS,
enhances
expression
intracellular
antioxidant
enzymes,
directs
polarization
M2
macrophages
by
secreting
AST
vesicles
via
exosomes.
The
living
hydrogel
sterilize
enhance
cell
proliferation
migration
promote
neoangiogenesis,
which
could
improve
infected
healing
female
mice.
The ISME Journal,
Journal Year:
2024,
Volume and Issue:
18(1)
Published: Jan. 1, 2024
Abstract
Elucidating
complex
interactions
between
bacteria
and
fungi
that
determine
microbial
community
structure,
composition,
functions
in
soil,
as
well
regulate
carbon
(C)
nutrient
fluxes,
is
crucial
to
understand
biogeochemical
cycles.
Among
the
various
interactions,
competition
for
resources
main
factor
determining
adaptation
niche
differentiation
these
two
big
groups
soil.
This
because
C
energy
limitations
growth
are
a
rule
rather
than
an
exception.
Here,
we
review
demands
of
fungi—the
major
kingdoms
soil—the
mechanisms
their
other
resources,
leading
differentiation,
global
change
impacts
on
this
competition.
The
normalized
utilization
preference
showed
1.4–5
times
more
efficient
uptake
simple
organic
compounds
substrates,
whereas
1.1–4.1
effective
utilizing
compounds.
Accordingly,
strongly
outcompete
while
take
advantage
Bacteria
also
compete
with
products
released
during
degradation
substrates.
Based
specifics,
differentiated
spatial,
temporal,
chemical
niches
will
increase
under
five
changes
including
elevated
CO2,
N
deposition,
soil
acidification,
warming,
drought.
Elevated
warming
bacterial
dominance,
acidification
drought
fungal
competitiveness.
Plants,
Journal Year:
2023,
Volume and Issue:
12(3), P. 629 - 629
Published: Jan. 31, 2023
Plants
are
affected
by
various
environmental
stresses
such
as
high
or
low
temperatures,
drought,
and
salt
levels,
which
can
disrupt
their
normal
cellular
functioning
impact
growth
productivity.
These
stressors
offer
a
major
constraint
to
the
morphological,
physiological,
biochemical
parameters;
thereby
attributing
serious
complications
in
of
crops
rice,
wheat,
corn.
Considering
strategic
intricate
association
soil
microbiota,
known
plant
growth-promoting
rhizobacteria
(PGPR),
with
roots,
PGPR
helps
plants
adapt
survive
under
changing
conditions
become
more
resilient
stress.
They
aid
nutrient
acquisition
regulation
water
content
also
play
role
regulating
osmotic
balance
ion
homeostasis.
Boosting
key
physiological
processes,
they
contribute
significantly
alleviation
stress
promoting
development
plants.
This
review
examines
use
increasing
tolerance
different
stresses,
focusing
on
uptake,
acquisition,
homeostasis,
balance,
well
effects
crop
yield
food
security.
Plant Stress,
Journal Year:
2023,
Volume and Issue:
10, P. 100283 - 100283
Published: Nov. 7, 2023
The
substantial
influence
of
microbes
on
crop
growth,
stress
resilience,
and
ecological
restoration
has
generated
considerable
interest
due
to
the
intricate
interplay
between
these
microorganisms
plants.
This
study
comprehensively
examines
diverse
mechanisms
through
which
contribute
plant
well-being,
mitigate
stress,
facilitate
phytoremediation
processes.
Microorganisms
encompassing
bacteria,
fungi,
archaea,
viruses,
have
demonstrated
their
knack
for
stirring
up
growth-enabling
hormones,
activating
pathways
tuned
ameliorating
availability
nutrients
by
means
fixation
solubilization
Furthermore,
such
also
display
immense
potential
in
field
strategies
aiding
plants
extraction,
alteration,
detoxification
contaminants
found
both
soil
water.
Complementing
this,
enable
phytoextraction,
rhizofiltration,
phytostabilization,
rhizodegradation,
owing
harmonious
interaction
with
purification
tainted
environments.
However,
it
is
critical
address
legal
issues,
moral
dilemmas,
unintended
consequences
as
are
increasingly
incorporated
into
sustainable
agriculture
methods.
Optimizing
microbial
therapies
ensuring
appropriate
use
offers
promising
insights
when
leveraging
cutting-edge
technologies
like
omics
genetic
engineering.
Coordination
among
academics,
practitioners,
policymakers
still
crucial
quest
a
more
robust
peaceful
coexistence
microbes,
plants,
ecosystems.
In
nutshell,
this
work
highlights
pivotal
role
that
poised
assume,
guiding
trajectory
agriculture,
alleviating
fostering
environmental
sustainability
far-reaching
implications.
Environmental Science Advances,
Journal Year:
2023,
Volume and Issue:
2(4), P. 586 - 611
Published: Jan. 1, 2023
Microalgae
are
a
source
of
scientific
curiosity
and
inspiration
for
their
utilization
as
‘inoculants’
in
agriculture
the
commercial
production
high-value
products.
The ISME Journal,
Journal Year:
2023,
Volume and Issue:
17(10), P. 1589 - 1600
Published: July 7, 2023
The
increasing
frequency
of
extreme
weather
events
highlights
the
need
to
understand
how
soil
microbiomes
respond
such
disturbances.
Here,
metagenomics
was
used
investigate
effects
future
climate
scenarios
(+0.6
°C
warming
and
altered
precipitation)
on
during
summers
2014-2019.
Unexpectedly,
Central
Europe
experienced
heatwaves
droughts
2018-2019,
causing
significant
impacts
structure,
assembly,
function
microbiomes.
Specifically,
relative
abundance
Actinobacteria
(bacteria),
Eurotiales
(fungi),
Vilmaviridae
(viruses)
significantly
increased
in
both
cropland
grassland.
contribution
homogeneous
selection
bacterial
community
assembly
from
40.0%
normal
51.9%
summers.
Moreover,
genes
associated
with
microbial
antioxidant
(Ni-SOD),
cell
wall
biosynthesis
(glmSMU,
murABCDEF),
heat
shock
proteins
(GroES/GroEL,
Hsp40),
sporulation
(spoIID,
spoVK)
were
identified
as
potential
contributors
drought-enriched
taxa,
their
expressions
confirmed
by
metatranscriptomics
2022.
impact
further
evident
taxonomic
profiles
721
recovered
metagenome-assembled
genomes
(MAGs).
Annotation
contigs
MAGs
suggested
that
may
have
a
competitive
advantage
due
geosmin
2-methylisoborneol.
Future
caused
similar
pattern
changes
communities
summers,
but
much
lesser
extent.
Soil
grassland
showed
greater
resilience
change
than
those
cropland.
Overall,
this
study
provides
comprehensive
framework
for
understanding
response
