Current Pollution Reports,
Journal Year:
2024,
Volume and Issue:
10(2), P. 312 - 325
Published: May 21, 2024
Abstract
Purpose
of
Review
This
study
aims
to
review
recent
literature
reporting
wastewater-based
surveillance
(WBS)
the
monkeypox
virus
(MPXV)
with
a
major
focus
on
sample
collection,
processing,
and
public
health
safety
issues.
Recent
Findings
Various
studies
revealed
presence
MPXV
genetic
markers
in
sewage,
wastewater
treatment
plants,
drainage
systems
hospitals
multiple
countries.
Summary
Mpox
(formally
monkeypox)
has
been
identified
more
than
hundred
countries,
confirming
at
least
93,937
cases
from
06
May
2022
03
February
2024.
The
MPXV,
causative
agent
for
mpox,
is
zoonotic
having
genome
DNA.
Major
symptoms
disease
are
rash,
fever,
headache,
chills
lymph
pain.
It
about
10%
case
fatality
rate,
without
any
approved
vaccine,
but
researchers
investigating
development
therapeutic
vaccines.
DNA
signature
long
reported
urine,
stool,
saliva,
semen,
spit
samples
clinical
patients,
make
feasible
tracking
wastewater.
Furthermore,
have
environmental
samples.
As
possible
hosts
(e.g.,
small
mammals
rodents),
their
detection
might
indicate
circulation
including
non-human
hosts.
persistence
infective
particles
ambient
environment
not
fully
investigated.
Also,
risks
transmission
through
contaminated
milieu
unknown.
WBS
can
be
an
effective
tool
identifying
hotspots
trends
communities.
Graphical
Frontiers in Science,
Journal Year:
2024,
Volume and Issue:
2
Published: April 25, 2024
This
article
advocates
for
mobilizing
pathogen
genomic
surveillance
to
contain
and
mitigate
health
threats
from
infectious
diseases
antimicrobial
resistance
(AMR),
building
upon
successes
achieved
by
large-scale
genome
sequencing
analysis
of
SARS-CoV-2
variants
in
guiding
COVID-19
monitoring
public
responses
adopting
a
One
Health
approach.
Capabilities
laboratory-based
epidemic
alert
systems
should
be
enhanced
fostering
(i)
universal
access
real-time
whole
sequence
(WGS)
data
pathogens
inform
clinical
practice,
infection
control,
policies,
vaccine
drug
research
development;
(ii)
integration
diagnostic
microbiology
data,
testing
asymptomatic
individuals,
epidemiological
into
programs;
(iii)
stronger
cross-sectorial
collaborations
between
healthcare,
health,
animal
environmental
using
approaches,
toward
understanding
the
ecology
transmission
pathways
AMR
across
ecosystems;
(iv)
international
collaboration
interconnection
networks,
harmonization
laboratory
methods,
standardization
methods
global
reporting,
including
on
variant
or
strain
nomenclature;
(v)
responsible
sharing
databases,
platforms
according
FAIR
(findability,
accessibility,
interoperability,
reusability)
principles;
(vi)
system
implementation
its
cost-effectiveness
different
settings.
Regional
policies
governance
initiatives
foster
concerted
development
efficient
utilization
protect
humans,
animals,
environment.
Science Advances,
Journal Year:
2024,
Volume and Issue:
10(2)
Published: Jan. 10, 2024
Miniaturized
mobile
electronic
system
is
an
effective
candidate
for
in
situ
exploration
of
confined
spaces.
However,
realizing
such
still
faces
challenges
powering
issue,
untethered
mobility,
wireless
data
acquisition,
sensing
versatility,
and
integration
small
scales.
Here,
we
report
a
battery-free,
wireless,
miniaturized
soft
electromagnetic
swimmer
(SES)
that
achieves
multiple
monitoring
capability
water
environments.
Through
radio
frequency
powering,
the
battery-free
SES
demonstrates
motions
spaces
with
considerable
moving
speed
under
resonance.
This
adopts
technologies
to
integrate
thin
multifunctional
bio/chemical
sensors
acquisition
module,
performs
real-time
quality
virus
contamination
detection
demonstrated
promising
limits
high
sensitivity.
All
are
transmitted
synchronously
displayed
on
smartphone
graphical
user
interface
via
near-field
communication.
Overall,
this
smart
broad
potential
space
exploration,
ranging
from
pathogen
pollution
investigation.
The Lancet Microbe,
Journal Year:
2024,
Volume and Issue:
unknown, P. 100939 - 100939
Published: Aug. 1, 2024
SummaryWastewater
surveillance
holds
great
promise
as
a
sensitive
method
to
detect
spillover
of
zoonotic
infections
and
early
pandemic
emergence,
thereby
informing
risk
mitigation
public
health
response.
Known
viruses
with
potential
are
shed
in
human
stool
or
urine,
both,
the
experiences
SARS-CoV-2,
monkeypox
virus,
Zika
virus
highlight
feasibility
community-based
wastewater
for
that
have
different
transmission
routes.
We
reviewed
shedding
data
prototype
representing
viral
families
concern
estimate
likely
sensitivity
compared
clinical
surveillance.
examined
how
on
detection,
together
genetic
sequences
animal
faecal
biomarkers,
could
be
used
identify
adaptation.
The
opportunities
challenges
associated
global
prevention
pandemics
described
this
Personal
View,
focusing
low-income
middle-income
countries,
where
emergence
is
highest.
propose
research
agenda
ensure
an
equitable
sustainable
solution
these
challenges.
Human Genomics,
Journal Year:
2024,
Volume and Issue:
18(1)
Published: Feb. 6, 2024
Abstract
Background
Periodic
bioinformatics-based
screening
of
wastewater
for
assessing
the
diversity
potential
human
viral
pathogens
circulating
in
a
given
community
may
help
to
identify
novel
or
potentially
emerging
infectious
diseases.
Any
identified
contigs
related
viruses
should
be
confirmed
with
targeted
and
clinical
testing.
Results
During
COVID-19
pandemic,
untreated
samples
were
collected
1-year
period
from
Great
Lakes
Water
Authority
Wastewater
Treatment
Facility
Detroit,
MI,
USA,
population
both
centralized
interceptor
sites
localized
neighborhood
sewersheds
was
investigated.
Clinical
cases
diseases
caused
by
tabulated
compared
data
monitoring.
In
addition
Betacoronavirus
,
comparison
using
assembled
against
custom
Swiss-Prot
virus
database
indicated
prevalence
other
pathogenic
genera,
including:
Orthopoxvirus
Rhadinovirus,
Parapoxvirus
Varicellovirus,
Hepatovirus,
Simplexvirus,
Bocaparvovirus,
Molluscipoxvirus,
Parechovirus,
Roseolovirus,
Lymphocryptovirus,
Alphavirus,
Spumavirus,
Lentivirus,
Deltaretrovirus,
Enterovirus,
Kobuvirus,
Gammaretrovirus,
Cardiovirus,
Erythroparvovirus,
Salivirus,
Rubivirus,
Orthohepevirus,
Cytomegalovirus,
Norovirus,
Mamastrovirus
.
Four
nearly
complete
genomes
recovered
Astrovirus,
Norovirus
Betapolyomavirus
genera
species
identified.
Conclusions
The
presented
findings
are
primarily
at
genus
level
can
serve
as
preliminary
“screening”
tool
that
indication
initiate
further
testing
confirmation
presence
associated
disease.
Integrating
innovative
environmental
microbiology
technologies
like
metagenomic
sequencing
epidemiology
offers
significant
opportunity
improve
monitoring
of,
predictive
intelligence
for,
viruses,
wastewater.
