Assessment of heavy metal accumulation and potential risks in surface sediment of estuary area: A case study of Dagu river

Marine Environmental Research, Journal Year: 2024, Volume and Issue: 196, P. 106416 - 106416

Published: Feb. 19, 2024

Language: Английский

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Heavy metals: toxicity and human health effects

Archives of Toxicology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 20, 2024

Abstract Heavy metals are naturally occurring components of the Earth’s crust and persistent environmental pollutants. Human exposure to heavy occurs via various pathways, including inhalation air/dust particles, ingesting contaminated water or soil, through food chain. Their bioaccumulation may lead diverse toxic effects affecting different body tissues organ systems. The toxicity depends on properties given metal, dose, route, duration (acute chronic), extent bioaccumulation. detrimental impacts human health largely linked their capacity interfere with antioxidant defense mechanisms, primarily interaction intracellular glutathione (GSH) sulfhydryl groups (R-SH) enzymes such as superoxide dismutase (SOD), catalase, peroxidase (GPx), reductase (GR), other enzyme Although arsenic (As) is believed bind directly critical thiols, alternative hydrogen peroxide production processes have also been postulated. known signaling pathways affect a variety cellular processes, cell growth, proliferation, survival, metabolism, apoptosis. For example, cadmium can BLC-2 family proteins involved in mitochondrial death overexpression antiapoptotic Bcl-2 suppression proapoptotic (BAX, BAK) thus increasing resistance cells undergo malignant transformation. Nuclear factor erythroid 2-related 2 (Nrf2) an important regulator enzymes, level oxidative stress, oxidants has shown act double-edged sword response arsenic-induced stress. Another mechanism significant threats metal (e.g., Pb) involves substitution essential calcium (Ca), copper (Cu), iron (Fe)) structurally similar (Cd) (Pb)) metal-binding sites proteins. Displaced redox (copper, iron, manganese) from natural catalyze decomposition Fenton reaction generate damaging ROS hydroxyl radicals, causing damage lipids, proteins, DNA. Conversely, some metals, cadmium, suppress synthesis nitric oxide radical (NO · ), manifested by altered vasorelaxation and, consequently, blood pressure regulation. Pb-induced stress be indirectly responsible for depletion due its (O ·− resulting formation potent biological oxidant, peroxynitrite (ONOO − ). This review comprehensively discusses mechanisms effects. Aluminum (Al), (Cd), (As), mercury (Hg), (Pb), chromium (Cr) roles development gastrointestinal, pulmonary, kidney, reproductive, neurodegenerative (Alzheimer’s Parkinson’s diseases), cardiovascular, cancer (e.g. renal, lung, skin, stomach) diseases discussed. A short account devoted detoxification chelation use ethylenediaminetetraacetic acid ( EDTA), dimercaprol (BAL), 2,3-dimercaptosuccinic (DMSA), 2,3-dimercapto-1-propane sulfonic (DMPS), penicillamine chelators.

Language: Английский

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Reinforcement mechanisms of cellulose nanofibers on cemented rockfill: Macroscopic, microscopic and molecular insights

Construction and Building Materials, Journal Year: 2025, Volume and Issue: 466, P. 140192 - 140192

Published: Feb. 6, 2025

Language: Английский

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Global soil pollution by toxic metals threatens agriculture and human health

Science, Journal Year: 2025, Volume and Issue: 388(6744), P. 316 - 321

Published: April 17, 2025

Toxic metal pollution is ubiquitous in soils, yet its worldwide distribution unknown. We analyzed a global database of soil by arsenic, cadmium, cobalt, chromium, copper, nickel, and lead at 796,084 sampling points from 1493 regional studies used machine learning techniques to map areas with exceedance agricultural human health thresholds. reveal previously unrecognized high-risk, metal-enriched zone low-latitude Eurasia, which attributed influential climatic, topographic, anthropogenic conditions. This feature can be regarded as signpost for the Anthropocene era. show that 14 17% cropland affected toxic globally estimate between 0.9 1.4 billion people live regions heightened public ecological risks.

Language: Английский

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Assessing temporal shifts in trophic diversity in fish assemblages after the Fundão dam collapse

Environmental Monitoring and Assessment, Journal Year: 2025, Volume and Issue: 197(4)

Published: March 13, 2025

Language: Английский

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Global and regional patterns of soil metal(loid) mobility and associated risks

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: March 26, 2025

Soil contamination by metals and metalloids (metal[loid]s) is a global issue with significant risks to human health, ecosystems, food security. Accurate risk assessment depends on understanding metal(loid) mobility, which dictates bioavailability environmental impact. Here we show theory-guided machine learning model that predicts soil fractionation across the globe. Our identifies total content organic carbon as primary drivers of mobility. We find 37% world's land at medium-to-high mobilization risk, hotspots in Russia, Chile, Canada, Namibia. analysis indicates efforts enhance sequestration may inadvertently increase Furthermore, Europe, divergence between spatial distributions mobile metal(loid)s uncovered. These findings offer crucial insights into providing robust tool for prioritizing mobility testing, raising awareness, informing sustainable management practices. Evaluating large scales nearly intractable laboratory experiments. This study uses methods map distribution analyzes its drivers.

Language: Английский

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Environmental pollution and human health risk due to tailings storage facilities in China

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 928, P. 172437 - 172437

Published: April 12, 2024

Language: Английский

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Mapping critical minerals projects and their intersection with Indigenous peoples' land rights in Australia

Energy Research & Social Science, Journal Year: 2024, Volume and Issue: 113, P. 103556 - 103556

Published: May 3, 2024

Vastly increased quantities of minerals and metals are needed to scale up renewable energy technologies. Indigenous peoples globally voicing concerns about how this will affect the speed mining development on their lands territories. In paper, we delineate areas Australia where peoples' interests in land formally recognised under legislation. These overlayed with critical project information calculate intersections across 14 commodities. Our results show that 57.8 % projects located have a right negotiate. Including native title claims, these rights available for 79.2 projects. We argue policies must consider upfront – not as an afterthought. To date, shared equitably wealth generated by Australia's mineral endowment. Inequitable outcomes continue without major policy reform.

Language: Английский

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Tailings storage facilities, failures and disaster risk

Nature Reviews Earth & Environment, Journal Year: 2024, Volume and Issue: 5(9), P. 612 - 630

Published: Aug. 6, 2024

Language: Английский

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Pollution and ecological risk assessment of heavy metals in anthropogenically-affected soils of Sudan: A systematic review and meta-analysis

Journal of Hazardous Materials Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100601 - 100601

Published: Jan. 1, 2025

Language: Английский

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