Nutrients,
Journal Year:
2020,
Volume and Issue:
12(4), P. 1158 - 1158
Published: April 21, 2020
Endocrine
disruptors
(EDCs)
have
been
associated
with
the
increased
incidence
of
metabolic
disorders.
In
this
work,
we
conducted
a
systematic
review
literature
in
order
to
identify
current
knowledge
interactions
between
EDCs
food,
gut
microbiota,
and
disorders
shed
light
on
complex
triad.
Exposure
induces
series
changes
including
microbial
dysbiosis
induction
xenobiotic
pathways
genes,
enzymes,
metabolites
involved
EDC
metabolism.
The
products
by-products
released
following
metabolism
can
be
taken
up
by
host;
therefore,
composition
microbiota
production
could
major
impact
host
development
diseases.
remediation
EDC-induced
might
represent
an
alternative
course
for
treatment
prevention
Frontiers in Immunology,
Journal Year:
2018,
Volume and Issue:
9
Published: Oct. 9, 2018
Post
birth
there
is
an
assault
on
all
mucosal
surfaces
including
the
skin.
The
intestinal
microbiome
important
participant
in
health
and
disease.
pattern
of
composition
concentration
varies
greatly.
Therefore
achieving
immunological
tolerance
first
three-four
years
life
critical
for
maintaining
throughout
a
lifetime.
Probiotic
bacteria
are
organisms
that
afford
beneficial
effects
to
host
certain
instances
may
protect
against
development
potential
benefits
modifying
microbial
cohort
therapeutic
benefit
evident
use
high
risks
groups
such
as
premature
infants,
traveller's
diarrhoea,
children
receiving
antibiotics
rotavirus
infections.
Probiotics
prebiotics
postulated
have
immunomodulating
capabilities
by
influencing
dampening
activity
pathobiont
microbes,
Escherichia
coli
Clostridia
perfringens.
Lactobacilli
Bifidobacteria
examples
probiotics
found
large
intestine
so
far,
afforded
varied
efficacy.
Most
likely
efficacy
probiotic
has
multifactorial
dependency,
namely
number
factors
include
agents
used,
dose,
dosing,
characteristics
underlying
luminal
environment
bacteriophages.
Bacteriophages
display
effective
local
protective
control
mechanism
barrier
commensal
pathobionts
establishing
symbiotic
relationship
with
host.
This
co-operation
defence
exploits
bacteriophage–mucin
glycoprotein
interactions
controls
bacterial
diversity
abundance
example
mucin
layers
gut.
Moreover,
importantly
be
dependent
incorporation
prebiotics,
just
how
abundant
diverse
virome
(e.g.,
temperate
phages)
predilection
specific
species.
Frontiers in Neuroscience,
Journal Year:
2018,
Volume and Issue:
12
Published: July 31, 2018
Diet
is
one
of
the
most
influential
environmental
factors
in
determining
composition
gastrointestinal
microbiota.
Microbial
dysbiosis
children
with
Autism
Spectrum
Disorder
(ASD)
and
impact
some
bacterial
taxa
on
symptoms
ASD
has
been
recognized.
Children
are
often
described
as
picky
eaters
low
intake
fiber-rich
foods,
including
fruits
vegetables.
However,
diet
microbiota
largely
unknown.
Herein,
fecal
samples,
3
day
food
diaries
Youth
Adolescence
Food
Frequency
questionnaire
(YAQ)
were
collected
from
(ASD;
n
=
26)
unaffected
controls
(CONT;
32).
Children's
determined
using
Pervasive
Developmental
Behavior
Inventory
Screening
Version
(PDDBI-SV).
Differences
at
phyla,
order,
family,
genus
level
between
CONT
observed.
Microbiota
was
investigated
relation
to
feeding
behavior,
nutrient
group
well
dietary
patterns
derived
YAQ.
In
ASD,
two
distinct
(DP)
associated
unique
microbial
profiles.
DP1,
characterized
by
higher
intakes
vegetables,
legumes,
nuts
seeds,
fruit,
refined
carbohydrates,
starchy
but
lower
sweets,
abundance
Enterobacteriaceae,
Lactococcus,
Roseburia,
Leuconostoc,
Ruminococcus.
DP2,
seeds
Barnesiellaceae
Alistipes
Streptophyta,
levels
propionate,
isobutyrate,
valerate,
isovalerate.
Peptostreptococcaceae
Faecalibacterium
predicted
social
deficit
scores
measured
PDDBI-SV.
Diet-associated
profiles
related
GI
symptoms,
no
significant
interaction
nutrition
predicting
conclusion,
VFA
concentrations
identified.
Future
studies
a
larger
sample
size
measuring
other
behaviors
needed
investigate
whether
may
be
modifiable
moderator
symptoms.
Frontiers in Immunology,
Journal Year:
2019,
Volume and Issue:
10
Published: Oct. 1, 2019
Since
bifidobacteria
are
among
the
pioneering
colonizers
of
human
infant
gut,
their
interaction
with
host
is
believed
to
start
soon
following
birth.
Several
members
Bifidobacterium
genus
purported
exert
various
health-promoting
effects
at
local
and
systemic
levels,
e.g.
limiting
pathogen
colonization/invasion,
influencing
gut
homeostasis
immune
system
through
changes
in
innate
and/or
adaptive
responses.
This
has
promoted
extensive
research
efforts
shed
light
on
precise
mechanisms
by
which
able
stimulate
interact
system.
These
studies
uncovered
a
variety
secreted
or
surface-associated
molecules
that
act
as
essential
mediators
for
establishment
bifidobacteria-host
dialogue,
allow
interactions
mucosa-associated
cells.
Additionally,
by-products
generated
from
bifidobacterial
carbohydrate
metabolism
vectors
directly
indirectly
trigger
response,
latter
stimulating
growth
other
commensal
microorganisms
such
propionate-
butyrate-producing
bacteria.
review
aimed
provide
comprehensive
overview
wide
strategies
employed
engage
Nutrients,
Journal Year:
2020,
Volume and Issue:
12(4), P. 1158 - 1158
Published: April 21, 2020
Endocrine
disruptors
(EDCs)
have
been
associated
with
the
increased
incidence
of
metabolic
disorders.
In
this
work,
we
conducted
a
systematic
review
literature
in
order
to
identify
current
knowledge
interactions
between
EDCs
food,
gut
microbiota,
and
disorders
shed
light
on
complex
triad.
Exposure
induces
series
changes
including
microbial
dysbiosis
induction
xenobiotic
pathways
genes,
enzymes,
metabolites
involved
EDC
metabolism.
The
products
by-products
released
following
metabolism
can
be
taken
up
by
host;
therefore,
composition
microbiota
production
could
major
impact
host
development
diseases.
remediation
EDC-induced
might
represent
an
alternative
course
for
treatment
prevention
