From microbes to microbiomes: Applications for plant health and sustainable agriculture

Phytopathology, Journal Year: 2024, Volume and Issue: 114(8), P. 1742 - 1752

Published: May 22, 2024

Plant-microbe interaction research has had a transformative trajectory, from individual microbial isolate studies to comprehensive analyses of plant microbiomes within the broader phytobiome framework. Acknowledging indispensable role in shaping health, agriculture, and ecosystem resilience, we underscore urgent need for sustainable crop production strategies face contemporary challenges. We discuss how synergies between advancements 'omics technologies artificial intelligence can help advance profound potential microbiomes. Furthermore, propose multifaceted approach encompassing translational considerations, transdisciplinary initiatives, public-private partnerships, regulatory policy development, pragmatic expectations practical application microbiome knowledge across diverse agricultural landscapes. advocate strategic collaboration intentional efforts unlock benefits offered by address pressing global issues food security. By emphasizing nuanced understanding complexities fostering realistic expectations, encourage scientific community navigate journey discoveries laboratory field applications. As companies specializing microbes undergo shifts, highlight necessity agriculture with site-specific management solutions. While cautioning against overpromising, excitement exploring many impacts microbiome-plant interactions. emphasize importance collaborative endeavors societal partners accelerate our collective capacity harness yet-to-be-discovered beneficial activities

Language: Английский

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Physical Activity Shapes the Intestinal Microbiome and Immunity of Healthy Mice but Has No Protective Effects against Colitis in MUC2 ^−/− Mice

mSystems, Journal Year: 2020, Volume and Issue: 5(5)

Published: Oct. 6, 2020

Perturbation in the gut microbial ecosystem has been associated with various diseases, including inflammatory bowel disease. Habitual physical activity, through its ability to modulate microbiome, recently shown prophylactically protect against chemically induced models of murine colitis. Here, we (i) confirm previous reports that activity limited but significant effects on microbiome mice and (ii) show such changes are anti-inflammatory states gut, as increased production beneficial short-chain fatty acids lower levels proinflammatory immune markers implicated human colitis; however, also (iii) these activity-derived benefits completely lost absence a healthy intestinal mucus layer, hallmark phenotype

Language: Английский

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Formation, characterization and modeling of emergent synthetic microbial communities

Computational and Structural Biotechnology Journal, Journal Year: 2021, Volume and Issue: 19, P. 1917 - 1927

Published: Jan. 1, 2021

Microbial communities colonize plant tissues and contribute to host function. How these form how individual members shaping the microbial community are not well understood. Synthetic communities, where defined isolates combined, can serve as valuable model systems for uncovering organizational principles of communities. Using genome-defined organisms, systematic analysis by computationally-based network reconstruction lead mechanistic insights metabolic interactions between species. In this study, 10 bacterial strains isolated from Populus deltoides rhizosphere were combined passaged in two different media environments stable The membership relative abundances stabilized after around 5 growth cycles resulted just a few dominant that depended on medium. To unravel underlying interactions, flux balance was used identify potential exchanges involved These analyses complemented curves isolates, pairwise interaction screens, metaproteomics community. A fast rate is identified one factor provide an advantage maintaining presence Final selection also depend selective antagonistic relationships exchanges. Revealing mechanisms among plant-associated microorganisms provides into strategies engineering potentially increase disease resistance. Further, deciphering potentials will enable design synthetic with desired biological functions.

Language: Английский

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Opportunities in optical and electrical single-cell technologies to study microbial ecosystems

Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14

Published: Aug. 25, 2023

New techniques are revolutionizing single-cell research, allowing us to study microbes at unprecedented scales and in unparalleled depth. This review highlights the state-of-the-art technologies analysis microbial ecology applications, with particular attention both optical tools, i.e., specialized use of flow cytometry Raman spectroscopy emerging electrical techniques. The objectives this include showcasing diversity approaches for studying microbiological phenomena, highlighting successful applications understanding systems, discussing techniques, encouraging combination established novel address research questions. aims answer key questions such as how have advanced our individual interacting cells, they been used uncultured microbes, which new tools will become widespread, contribute knowledge ecological interactions.

Language: Английский

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Understanding Microbiome Stability in a Changing World

mSystems, Journal Year: 2018, Volume and Issue: 3(2)

Published: March 19, 2018

Microbiomes underpin biogeochemical processes, sustain the bases of food webs, and recycle carbon nutrients. Thus, microbes are frontline players in determining ecosystem responses to environmental change.

Language: Английский

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