Ultra-processed foods and coronary artery disease severity: a cross-sectional study of at-risk normal-weight and overweight patients undergoing elective angiography

Journal of Health Population and Nutrition, Journal Year: 2025, Volume and Issue: 44(1)

Published: March 5, 2025

There is growing interest in the connection between ultra-processed food (UPF) and cardiovascular diseases. This study explores how UPF intake relates to severity of coronary artery disease (CAD) at-risk patients undergoing elective angiography. Data covering demographic, clinical details, dietary intakes (using a validated frequency questionnaire) were gathered from Nutrition Heshmat Registry (NUTHER) Rasht, Iran. consumption was evaluated using NOVA classification system, with exception core grain foods. The comprised 1,015 participants, who classified based on CAD Gensini score (severe-CAD = ≥ 60). Logistic regression used analyze odd ratio (OR) 95%confidence interval (95%CI) for severe-CAD across quartiles (percentage energy), each 10% increase intake. Restricted cubic spline (RCS) employed explore nonlinear relationships severe-CAD. Following controlling potential confounders, normal-weight participants highest quartile exhibited about 5 times greater odds than those lowest category (OR(95%CI): 5.01 (1.89, 13.29); P-for-trend 0.002). Overweight/obese higher had approximately 2-3.5 1st (ORs (95%CIs): 3rd 1.91 (1.14, 3.21); 4th quartile: 3.53 (2.07, 5.99); < 0.001). Each daily energy associated 1.6-2 increased risk among overweight/obese individuals (95%CIs) 1.64 (1.28, 2.11), 2.24 (1.24, 4.05), respectively). RCS analysis showed an upward trend toward relation (P-for-overall-trend 0.0001; P-for-nonlinearity 0.005). findings obtained underscore direct association progression patients, independent BMI. However, further prospective studies are essential confirm these results better understand this relationship.

Language: Английский

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The Impact of Ultra-Processed Foods on Cardiovascular Diseases and Cancer: Epidemiological and Mechanistic Insights

Aspects of Molecular Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 100072 - 100072

Published: March 1, 2025

Language: Английский

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Characterization of Nova-classified foods in a large cohort of Norwegian colorectal cancer screening participants

Norsk tidsskrift for ernæring, Journal Year: 2025, Volume and Issue: 23(1), P. 7 - 19

Published: March 10, 2025

Language: Английский

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Ultra-processed foods and cardio-kidney-metabolic syndrome: A review of recent evidence

European Journal of Internal Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

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Existing food processing classifications overlook the phytochemical composition of processed plant-based protein-rich foods

Nature Food, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

Abstract According to existing food processing classification systems, plant-based protein-rich (PBPR) foods are often considered ‘ultra-processed’—and therefore perceived as unhealthy—despite their ability provide various bioactive compounds beneficial for human health. Here we used a non-targeted metabolomics approach analyse the impact of on biochemical composition PBPR foods. Our results show that systems may questionable categories without considering overall composition, including phytochemicals. An analysis focusing specifically soy-based products manufactured using technologies showed no clear distinctions between groups in principal component based NOVA and Poti classification. However, differences were found phytochemical profile. Although welcome attempt guide consumers towards healthy choices, they should be improved more accurately reflect

Language: Английский

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Advancing The FDA’s Human Foods Program Through Additional Authorities And User Fees

Health Affairs, Journal Year: 2025, Volume and Issue: 44(4), P. 458 - 466

Published: April 1, 2025

The Food and Drug Administration (FDA) lacks certain authorities is persistently underresourced to fulfill its mission of protecting the public by ensuring that foods are safe, wholesome, sanitary, properly labeled. Particularly concerning gaps exist in pre- postmarket oversight food ingredients often found ultraprocessed foods. Numerous substances either have evidence harm or unknown FDA public. Additional resources necessary. User fees been successfully implemented provide for other programs under purview. This legal policy analysis evaluates FDA's food-related would be amenable a new user fee program. It reviews domains where enhanced may warranted. We find comprehensive program benefit industry generate targeted strengthen agency's oversight.

Language: Английский

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Ultra-Processed Food Consumption Among College Students and Their Association With Body Composition, Bowel Movements and Menstrual Cycle

International Journal of Public Health, Journal Year: 2025, Volume and Issue: 70

Published: April 8, 2025

Objectives The current research aimed to explore the association of ultra-processed food consumption among college students with body composition, bowel movements, and menstrual irregularities a focus on females. Methods A cross-sectional study was conducted in Pune, India 110 university both genders aged 18–25 years. developed validated Food Frequency Questionnaire (FFQ) based NOVA classification used evaluate UPF consumption, while Constipation Scoring System (CSS) Premenstrual Symptoms Screening Tool assessed habits health, respectively. Anthropometric measurements, including BMI, fat percentage,and visceral were recorded using an Omron Karada Analyzer. Results higher percentage participants female (74.8%). Most (52.3%) consumed more than three meals daily, 42.1% ate outside 2–3 times per week. Higher showed trend toward increased (p = 0.053) significantly associated greater accumulation &lt; 0.05). No significant associations found between intake movement, gastrointestinal symptoms, or cycle &gt; Conclusion percentage, though not statistically significant. These findings highlight need reduce mitigate potential risks adiposity metabolic disturbances.

Language: Английский

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Impact of Ultra-processed Foods on Human Health: A Comprehensive Review of Genomic Instability and Molecular Mechanisms

Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 112800 - 112800

Published: April 1, 2025

Language: Английский

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Making Sense of the Relationship Between Ultra-Processed Foods, Obesity, and Other Chronic Diseases

Nutrients, Journal Year: 2024, Volume and Issue: 16(23), P. 4039 - 4039

Published: Nov. 26, 2024

Ultra-processed foods (UPFs) is a food category within the NOVA system. The key feature of UPFs are that have been highly processed and contain various additives, especially those industrially produced. It claimed inherently unhealthy. classification system controversial. This paper critically evaluates evidence. In stark contrast to conventional systems for classification, disregards nutritional values foods. As result, many generally considered be healthy included as UPFs, whereas unhealthy excluded. Epidemiological studies, mainly prospective cohort consistently reported an association between intake risk obesity, cardiovascular disease (CVD), type 2 diabetes, common mental disorders (especially depression), all-cause mortality. A similar has cancer hypertension, but supporting evidence weaker. most plausible explanation this associations largely due limited number foods, such meat sugar-sweetened beverages. Studies relationship obesity present different picture. There much suggests play major causal role in obesity. high contents fat, sugar, carbohydrates, sodium commonly makes these hyperpalatable. addition, typically energy density. result two features people consume excessive when presented with UPFs. Because include wide range which healthy, it likely while obesogenic, others not.

Language: Английский

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Mediterranean Diet and Ultra-Processed Food Intake in Older Australian Adults—Associations with Frailty and Cardiometabolic Conditions

Nutrients, Journal Year: 2024, Volume and Issue: 16(17), P. 2978 - 2978

Published: Sept. 3, 2024

Dietary patterns contribute to overall health and diseases of ageing but are understudied in older adults. As such, we first aimed develop dietary indices quantify Mediterranean Diet Score (MDS) utilisation Ultra-processed Food (UPF) intake a well-characterised cohort relatively healthy community-dwelling Australian Second, understand the relationship between these scores association with prevalent cardiometabolic disease frailty. Our major findings that this population adults, (a) pre-frailty frailty associated reduced MDS increased UPF intake; (b) adherence eating does not preclude high (and vice versa); (c) an pattern prevent risk higher intakes. should be encouraged adults potentially reduce frailty, while impact further explored given convenience foods provide whose access unprocessed food may limited due socioeconomic, health, lifestyle factors.

Language: Английский

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