Medical Research Archives,
Journal Year:
2023,
Volume and Issue:
11(10)
Published: Jan. 1, 2023
his
article
discusses
the
gradual
increase
in
Deaths
of
Despair
United
States,
followed
by
a
reversal
increased
life
expectancy
trend
for
subset
population.
This
phenomenon
is
examined
context
pronounced
social
and
health
inequities
linked
to
globalization
capitalism
as
well
overall
negative
implications
COVID-19
pandemic
subsequent
socio-economic
crisis,
all
having
potential
further
worsen
US
but
also
globally.
The
development
effective
actionable
solutions
requires
an
in-depth
understanding
root
causes
decrease
population-level
expectancy.
While
focusing
on
Death
brings
attention
role
class
creation
mortality
rates,
this
approach
should
be
part
larger
examination
contributing
factors.
Scrutinizing
impact
other
location
factors
such
race,
gender,
age,
sexual
orientation
identity,
migration,
citizenship
status,
along
with
their
interaction
equally
important.
Research
approaches
that
allow
stratification
analyses
population
groups
are
needed
facilitate
better
observed
decreases
Such
require
long-term
ongoing
investments
research
intentional
collection
indicators
could
reveal
breadth
depth
pathways
through
which
they
lead
rates
various
groups.
sustained
financial
investment
efforts
required
examine
inform
implementation
protective
policies
reverse
have
bring
societal
dividends.
An
indirect
outcome
reduction
adoption
individuals
populations
regain
trust
institutions
and,
result,
enhance
active
political
participation
voter
turnout
decreased
radicalization.
SSM - Population Health,
Journal Year:
2025,
Volume and Issue:
29, P. 101748 - 101748
Published: Jan. 5, 2025
Growing
educational
disparities
in
mortality
due
to
suicide,
drug
overdose,
or
alcohol-related
liver
disease
-
"deaths
of
despair"
(DoD)
have
received
increased
attention
research
and
public
debate.
However,
no
study
has
investigated
differences
despair-related
outside
North
America.
Thus,
the
aim
this
was
investigate
changes
association
between
academic
achievement
compulsory
school
subsequent
all-cause
(ACM)
DoD
1990
2018
Swedish
youths.
Register
data
on
all
students
graduating
from
Sweden
2010
were
used
(N
=
2
252
938).
Students
followed
for
a
maximum
8
years
using
discrete
time
proportional
hazard
models.
Academic
measured
by
grades
at
end
school.
ACM
declined
medium/high
achieving
but
not
low-achieving
youths,
while
slightly
markedly
resulting
growing
achievement-related
both
types
mortality.
The
trends
primarily
driven
native-born
youth
girls.
youths
resemble
American
working-age
population,
partly
contrasts
with
corresponding
other
European
countries.
Future
should
if
underlying
causes
that
been
emphasized
context
socio-economic
transformations
greater
supply
drugs
also
contributed
trends.
International Journal of Epidemiology,
Journal Year:
2024,
Volume and Issue:
53(2)
Published: Feb. 14, 2024
Rising
midlife
mortality
in
the
USA
has
raised
concerns,
particularly
increase
'deaths
of
despair'
(due
to
drugs,
alcohol
and
suicide).
Life
expectancy
is
also
stalling
other
countries
such
as
UK,
but
how
trends
are
evolving
outside
less
understood.
We
provide
a
synthesis
cause-specific
(25-64
years
age)
for
UK
well
high-income
Central
Eastern
European
(CEE)
countries.
American Journal of Men s Health,
Journal Year:
2025,
Volume and Issue:
19(2)
Published: March 1, 2025
This
qualitative
study
explores
the
factors
contributing
to
gender-based
inequalities
in
"deaths
of
despair"
(DoD)
-
those
deaths
from
suicide,
drug
overdoses,
and
alcohol-specific
causes
among
men
two
deindustrialised
towns
North
East
England.
Understanding
disparities
these
death
sheds
important
light
on
how
social
economic
intersect
with
certain
facets
masculinity,
such
as
stoicism
self-reliance,
drive
vulnerability.
Data
were
collected
through
semi-structured
interviews
one
focus
group
54
stakeholders
people
whose
work
is
related
DoD,
mental
health
treatment
public
practice
community
members
Middlesbrough
South
Tyneside,
above
average
rates
DoD.
Participants
included
both
women,
predominantly
middle-age
or
older,
most
participants
unemployed
retired.
analysed
using
Iterative
Categorisation,
findings
interpreted
thematic
analysis.
The
generated
three
key
themes:
industrial
history
masculinity
class,
a
barrier
help-seeking.
demonstrate
that
decline
following
deindustrialisation
resulted
distress
created
unique
risk
for
substance
use
self-harm
men.
These
results
suggest
effective
interventions
reduce
DoD
post-industrial
settings
must
avoid
pathologising
itself.
Instead,
strategies
should
broader
structural
forces
undermine
men's
access
stable,
fulfilling
employment
offering
forms
support
are
compatible
masculine
identity.
By
addressing
determinants,
can
more
effectively
close
rate
areas.
Sociology of Health & Illness,
Journal Year:
2024,
Volume and Issue:
46(8), P. 1749 - 1771
Published: June 26, 2024
Abstract
Class‐based
perspectives
on
the
persistent
social
gradients
in
health
within
modern
welfare
states
largely
focus
adverse
consequences
of
unfettered
neoliberalism
and
entrenched
meritocratic
socioeconomic
selection.
Namely,
neoliberal‐driven
economic
inequality
has
fuelled
resentment
stress
among
lower‐status
groups,
while
these
groups
have
become
more
homogeneous
with
regard
to
behaviours
outcomes.
We
synthesise
several
sociological
historical
literatures
argue
that,
addition
class‐based
explanations,
may
contribute
due
elite
class
self‐interest—in
particular
elites’
preferences
for
overdiagnosis,
overprescription
costly
high‐technology
medical
treatments
over
disease
prevention,
increased
tolerance
regulatory
capture.
demonstrate
that
this
self‐interest
provides
parsimonious
explanations
contemporary
trends
U.S.
including
(A)
supply‐side
factors
drug‐related
deaths,
(B)
longitudinal
obesity
chronic
mortality
(C)
immigrant
advantage.
conclude
theories
usefully
complement
psychosocial
effects
selection
answering
recent
calls
research
role
advantaged
play
generating
inequalities
health,
moves
beyond
technological
determinism
sociology.
Life
expectancy
in
England
and
Wales
has
diverged
from
its
high-income
peers
since
2011,
raising
concerns
that
may
become
an
international
life
laggard
like
the
United
States
of
America
(USA).
Using
contour
decomposition
method,
we
decompose
gaps
male
female
between
20
individual
countries
2019
into:
(a)
pre-existing
differences
age-
cause-specific
death
rates
2011;
(b)
diverging
trends
these
2011–19.
Focusing
on
mortality
trends,
find
external
causes
at
young-to-middle
ages,
cardiometabolic
middle-to-older
dementia
older
ages
contributed
most
to
gaps.
Although
there
are
parallels
USA,
is
experiencing
distinct
trends.
Whether
entering
a
period
more
generalized
stagnation
will
be
important
question
monitor.
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring,
Journal Year:
2024,
Volume and Issue:
16(3)
Published: July 1, 2024
Abstract
INTRODUCTION
This
study
investigates
the
relationship
between
cognitive
functioning
and
59
modifiable
intrinsic
factors
at
cusp
of
midlife.
METHODS
We
analyzed
data
from
1221
participants
in
Colorado
Adoption/Twin
Study
Lifespan
behavioral
development
aging
(CATSLife;
M
age
=
33.20,
%Female
52.74).
assessed
impact
on
using
regularized
regression
co‐twin
control
models,
controlling
for
earlier‐life
gray
matter
volume.
RESULTS
Eight
robust
were
identified,
including
education
attainment,
complexity,
purpose‐in‐life,
smoking
status.
Twins
reporting
higher
levels
complexity
purpose‐in‐life
showed
better
performance
than
their
cotwin,
while
was
negatively
associated.
Using
meta‐analytically
derived
effect
size
threshold,
we
additionally
identified
that
twins
experiencing
more
financial
difficulty
tend
to
perform
less
well
compared
with
cotwin.
DISCUSSION
The
findings
highlight
early
midlife
link
lifestyle/psychological
factors,
beyond
prior
performance,
brain
status,
genetic
familial
confounders.
Our
results
further
potential
established
adulthood
as
a
crucial
window
dementia
prevention
interventions
targeting
lifestyle
psychosocial
factors.
Highlights
Cog
complexity(+),
purpose‐in‐life(+)
associated
cognition
Smoking(−)
also
Results
consistent
environmental
confounds.
Association
EA
might
be
mostly
confounded.
BMJ Open,
Journal Year:
2023,
Volume and Issue:
13(10), P. e068733 - e068733
Published: Oct. 1, 2023
Introduction
A
rise
in
premature
mortality—defined
here
as
death
during
the
most
productive
years
of
life,
between
adolescence
and
middle
adulthood
(15–60
years)—is
contributing
to
stalling
life
expectancy
high-income
countries.
Causes
mortality
vary,
but
often
include
substance
misuse,
suicide,
unintentional
injury
non-communicable
disease.
The
development
evidence-informed
policy
frameworks
guide
new
approaches
prevention
require
knowledge
early
targets
for
intervention,
interactions
higher
level
drivers.
Here,
we
aim
to:
(1)
identify
systematic
reviews
with
or
without
meta-analyses
focused
on
intervention
(in
which
are
causes
that
can,
at
least
hypothetically,
be
modified
reduce
risk);
(2)
evaluate
review
quality
risk
bias;
(3)
compare
each
review’s,
their
relevant
primary
studies,
findings
existing
evidence
gaps.
Methods
analysis
In
May
2023,
searched
electronic
databases
(MEDLINE,
PubMed,
Embase,
Cochrane
Library)
peer-reviewed
papers
published
English
language
12
from
2012
2023
examined
mortality.
Screening
will
narrow
these
focus
meta-analyses,
papers.
Our
outcome
is
ages
15
60
years;
potential
measured
prior
death.
MeaSurement
Tool
Assess
Reviews
(AMSTAR
2)
used
assess
bias
within
included
reviews.
Results
synthesised
narratively
due
anticipated
heterogeneity
studies
contained
Ethics
dissemination
This
synthesise
reviewed
meaning
ethics
committee
approval
not
required.
inform
cross-cohort
consortium
development,
a
journal,
presented
national
international
conferences.
PROSPERO
registration
number
CRD42022355861.
SSM - Mental Health,
Journal Year:
2024,
Volume and Issue:
5, P. 100324 - 100324
Published: May 20, 2024
Rising
mortality
due
to
suicides,
overdoses,
and
substance-related
diseases,
also
called
"deaths
of
despair,"
has
attracted
significant
academic,
public,
media
attention
in
recent
years.
This
type
mortality,
key
precursor
"diseases
despair"
like
depressive
mood
problems,
tend
concentrate
people
affected
by
deindustrialization
the
loss
well-paid
industrial
jobs,
that
is,
working-age
adults
with
less
than
a
BA
degree.
It
is
thought
risks
build
up
when
young
education
struggle
find
decent
jobs
upon
entering
labor
market,
which
turn
triggers
(1)
subjective
perceptions
being
stuck
lower
socioeconomic
rungs;
(2)
exposure
chronic
stressors
various
domains
(e.g.,
housing,
relationships).
study
examined
whether
wages
were
related
diseases
despair
(i.e.,
problems)
through
these
two
types
processes
longitudinal
sample
(N
=
543)
overrepresenting
Canadian
educational
attainment
followed
from
their
mid-teens
mid-20s.
Psychological
outcomes
self-reported,
whereas
was
assessed
gold-standard
interview-based
protocol.
After
taking
into
account
potential
confounders
measured
adolescence
stressor
exposure,
mental
health
symptoms),
results
show
early
adulthood
(in
mid-20s)
indirectly
associated
depressed
problems
mid-20s,
internal
psychological
external
stressors.
The
specific
play
varied
outcome.
For
mood,
one's
relative
position
emerged
as
particularly
relevant,
for
indirect
associations
only
both
exposures
considered
jointly.
Access
offering
good
among
without
university
degrees
should
thus
be
designing
policies
aimed
at
reducing
younger
generations.