The Role of Heat Shock Protein (Hsp) Chaperones in Environmental Stress Adaptation and Virulence of Plant Pathogenic Bacteria

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(2), P. 528 - 528

Published: Jan. 9, 2025

Plant pathogenic bacteria are responsible for a substantial number of plant diseases worldwide, resulting in significant economic losses. Bacteria exposed to numerous stress factors during their epiphytic life and within the host. Their ability survive host cause symptomatic infections depends on capacity overcome stressors. have evolved range defensive adaptive mechanisms thrive under varying environmental conditions. One such mechanism involves induction chaperone proteins that belong heat shock protein (Hsp) family. Together with proteases, these integral components quality control system (PQCS), which is essential maintaining cellular proteostasis. However, knowledge action considerably less extensive than human animal pathogens. This study discusses modulation Hsp levels by phytopathogenic response conditions, including elevated temperature, oxidative stress, changes pH or osmolarity environment, variable conditions infection. All influence bacterial virulence. Finally, secretion GroEL DnaK outside cell considered potentially important virulence trait.

Language: Английский

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Advances in understanding the plant-Ralstonia solanacearum interactions: Unraveling the dynamics, mechanisms, and implications for crop disease resistance

New Crops, Journal Year: 2024, Volume and Issue: 1, P. 100014 - 100014

Published: Feb. 6, 2024

Plant diseases caused by various pathogenic microorganisms can cause substantial reductions in agricultural crop yield and quality, resulting significant economic losses posing a threat to global food security. Understanding the mechanisms of plant - pathogen interactions is essential for developing genetic strategies safeguard crops against disease. Ralstonia solanacearum, soil-borne importance, has emerged as prominent model studying plant-pathogenic bacteria due its extensive diversity, prolonged environmental persistence, unusually broad host range, notably, considerable impact on agriculture. To successfully invade propagate plants, R. solanacearum employs diverse extracellular factors intracellular type III effectors (T3Es) evade or disrupt immunity. In response, plants have evolved dual-layered innate immune detection-and-response systems, represented pattern-triggered immunity (PTI)—mediated cell-surface pattern recognition receptors (PRRs)—and effector-triggered (ETI)—mediated nucleotide-binding leucine-rich repeat (NLRs). Over past three decades, many contributing dynamic between susceptible been identified. This comprehensive overview aims summarize current understanding known virulence suppressing T3E signaling pathways, well PRRs their target PAMPs (pathogen-associated molecular patterns), NLR-mediated avirulent T3Es that govern – interactions. Additionally, we highlight endeavors aimed at applying this knowledge enhanced disease resistance tools, address prevailing challenges, provide insights into future research perspectives.

Language: Английский

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Regulation and inhibition of type III secretion systems in plant pathogenic bacteria

Phytopathology Research, Journal Year: 2025, Volume and Issue: 7(1)

Published: Feb. 20, 2025

Abstract Type III secretion systems (T3SS) are syringe-like apparatuses acting as protein transport nanomachines found in most Gram-negative bacterial pathogens. They can inject effector proteins into the host cell cytoplasm, crossing membrane, and cause infection. Due to their critical role pathogenicity, T3SS represent attractive targets for vaccinations disease treatments. This review elucidates overarching structural framework operational mechanisms of while also delineating responsiveness phytobacterial host-derived signals nuanced orchestration activities by environmental stimuli. discussion encompasses shared features idiosyncratic attributes among a spectrum pathogens, including but not limited Pseudomonas syringae , Ralstonia Xanthomonas Erwinia . Additionally, we scrutinize contribution natural products synthetic chemicals inhibitors, elucidating hallmark ongoing quest design novel drugs. An in-depth comprehension functionality modes action diverse inhibitors holds promise developing innovative drugs aimed at swiftly suppressing phyto-pathogenicity elicited species.

Language: Английский

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Cell wall-mediated root development is targeted by a soil-borne bacterial pathogen to promote infection

Cell Reports, Journal Year: 2024, Volume and Issue: 43(5), P. 114179 - 114179

Published: April 30, 2024

Plant pathogens manipulate host development, facilitating colonization and proliferation. Ralstonia solanacearum is a soil-borne bacterial pathogen that penetrates roots colonizes plants through the vascular system, causing wilting death. Here, we find RipAC, an effector protein from R. solanacearum, alters root development in Arabidopsis, promoting formation of lateral hairs. RipAC interacts with CELLULOSE SYNTHASE (CESA)-INTERACTIVE PROTEIN 1 (CSI1), which regulates activity CESA complexes at plasma membrane. disrupts CESA-CSI1 interaction, leading to reduction cellulose content, developmental alterations, promotion pathogenicity. We CSI1 also associates receptor kinase FERONIA, forming complex negatively immunity roots; this however, not affected by RipAC. Our work reveals virulence strategy selectively affects activities target, anatomical alterations facilitate infection without activation immunity.

Language: Английский

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Plant secondary metabolites-mediated plant defense against bacteria and fungi pathogens

Plant Physiology and Biochemistry, Journal Year: 2024, Volume and Issue: 217, P. 109224 - 109224

Published: Oct. 20, 2024

Language: Английский

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Diversity of Endophytes of Actinidia arguta in Different Seasons

Life, Journal Year: 2024, Volume and Issue: 14(1), P. 149 - 149

Published: Jan. 19, 2024

The seasonal changes in environmental conditions can alter the growth states of host plants, thereby affecting living environment endophytes and forming different endophytic communities. This study employs Illumina MiSeq next-generation sequencing to analyze 16SrRNA ITS rDNA 24 samples Actinidia arguta stem tissues across seasons. results revealed a high richness diversity arguta, with significant variations microbial community richness. identified 897 genera 36 phyla for bacteria 251 8 fungi. Notably, 69 bacterial 19 fungal significantly contributed differences structure A distinctive feature coexistence community, both specific conservative seasons, was observed. winter demonstrated higher compared other Environmental factors likely influence optimal timing endophyte colonization. Solar radiation, temperature, precipitation, relative humidity impact In addition, show nutritional modes degradation, ligninolysis, ureolysis functions endophytes. elucidates potential role assisting adapting provides theoretical basis further exploration functional strains.

Language: Английский

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Navigating the signaling landscape of Ralstonia solanacearum: a study of bacterial two-component systems

World Journal of Microbiology and Biotechnology, Journal Year: 2024, Volume and Issue: 40(5)

Published: April 2, 2024

Language: Английский

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Friends and Foes: Bacteria of the Hydroponic Plant Microbiome

Plants, Journal Year: 2024, Volume and Issue: 13(21), P. 3069 - 3069

Published: Oct. 31, 2024

Hydroponic greenhouses and vertical farms provide an alternative crop production strategy in regions that experience low temperatures, suboptimal sunlight, or inadequate soil quality. However, hydroponic systems are soilless and, therefore, have vastly different bacterial microbiota than plants grown soil. This review highlights some of the most prevalent plant growth-promoting bacteria (PGPB) destructive phytopathogenic dominate systems. A complete understanding which increase yields ways to mitigate loss from disease critical advancing microbiome research. The section focussing on putative biological pathways for growth promotion evidence increased productivity by these organisms. Seven genera examined detail, including

Language: Английский

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Eucalyptus grandis WRKY genes provide insight into the role of arbuscular mycorrhizal symbiosis in defense against Ralstonia solanacearum

Frontiers in Plant Science, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 7, 2025

WRKY transcription factors are essential for plant growth, health, and responses to biotic abiotic stress. In this study, we performed a deep in silico characterization of the gene family genome Eucalyptus grandis. We also analyzed expression profiles these genes upon colonization by arbuscular mycorrhizal fungus (AMF) Rhizophagus irregularis (Ri) infection with bacterial pathogen Ralstonia solanacearum (Rs). A total 117 EgWRKYs were identified. Phylogenetic analysis divided EgWRKY proteins into three groups: group I (21 proteins, 17.95%), II (65 55.56%), III (24 20.51%). Additionally, seven (5.98%) categorized IV due absence domain or zinc-finger structure. All distributed irregularly across 11 chromosomes, 25 pairs identified as segmental duplicates four tandem duplicates. The promoter regions 50% members each subfamily contain hormone-related cis-elements associated defense responses, such ABREs, TGACG motifs, CGTCA motifs. subfamilies (except IV-b IV-c) AW-boxes, which related induction. Furthermore, transcriptomic revealed that 21 responsive AMF Ri, 13 8 strongly up- downregulated, respectively. Several (including EgWRKY116, EgWRKY62, EgWRKY107) significantly induced Ri; might enhance E. grandis against Rs. Therefore, regulated colonization, some improve R. solanacearum. These findings provide insights involved interactions among host plant, AMFs,

Language: Английский

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Genome mining to elucidate antimicrobial and plant growth promoting potentials in Lactic acid bacteria

European Journal of Plant Pathology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

Language: Английский

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