Depression and risk of sarcopenia: a national cohort and Mendelian randomization study

Frontiers in Psychiatry, Journal Year: 2023, Volume and Issue: 14

Published: Oct. 18, 2023

Background Depression and the increased risk of sarcopenia are prevalent among elderly population. However, causal associations between these factors remain unclear. To investigate potential association depression in older adults, this study was performed. Methods In baseline survey, a total 14,258 individuals aged 40 above from China Health Retirement Longitudinal Study (2015) participated. We initially described prevalence disease. Then, logistic regression restricted cubic spline (RCS) were conducted to assess relationship sarcopenia. Subgroup analysis performed validate robustness findings. Additionally, we Mendelian randomization using inverse variance weighting estimator Furthermore, adopted six methods, including MR-Egger, simple median, weighted maximum likelihood, robust adjusted profile score (RAPS), MR Pleiotropy Residual Sum Outlier (MR-PRESSO), for sensitivity analyses. Results patients exhibited higher risks all five models adjusting different covariates ( P < 0.05). The RCS demonstrated linear subgroup analysis, observed participants 60−70, married or cohabiting individuals, non-smokers, non-drinkers, those with less than 8 h sleep, BMI below 24, hypertension (all results revealed that genetically proxied led reduction appendicular skeletal muscle mass Conclusion Our provides observational evidences can lead This finding emphasizes importance timely identification management depression, as well implementing targeted educational programs part comprehensive strategies prevent

Language: Английский

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Trends and age-period-cohort effect on the incidence of falls from 1990 to 2019 in BRICS

Heliyon, Journal Year: 2024, Volume and Issue: 10(5), P. e26771 - e26771

Published: Feb. 21, 2024

BackgroundThe increasing burden of falls in BRICS countries warrants a comprehensive investigation to understand the dynamics and trends. This study utilized data from Global Burden Disease Study (GBD) 2019 assess fall incidence rates Brazil, Russia, India, China, South Africa (BRICS) provide valuable insights for development targeted prevention management strategies.MethodsData GBD were employed estimate rates. The age-period-cohort (APC) model analysis, implemented using R 4.3.0 software package apc, examine trends 1990 2019.ResultsIn 2019, nations collectively reported 32.32 million cases. overall rate increased 2681.7 per 100,000 people 1990–2896.3 2019. China India exhibited escalating trends, with experiencing highest growth at 21%, followed by 5.8%. displayed comparatively lower increase. Notably, 90–94 age group most significant deterioration, men women annual increases 4.23% 1.77%, respectively. Age effects indicated higher susceptibility among preschool children elderly. Period revealed no improvement state (2005–2019) (2015–2019). Cohort adversely impacted individuals born earlier Africa.ConclusionThe present highlights consistent upward trend across With an aging population, fall-related diseases is on rise these nations. Our results underscore necessity formulating evidence-based disease approaches tailored distinctive demographic attributes each nation. Addressing crucial mitigating growing impact public health countries.

Language: Английский

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The Role of Depression and Anxiety in the Relationship Between Arthritis and Cognitive Impairment in Chinese Older Adults

American Journal of Geriatric Psychiatry, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 1, 2024

Language: Английский

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Perfil sociodemográfico de los adultos mayores físicamente activos según el tipo de actividades de-portivas practicado: gimnasia, actividades acuáticas, yoga, pilates y danza (Sociodemographic profile of physically active older adults according to the type of physical activities practiced: Gymnastic Exercises, Aquatic Activities, Yoga, Pilates and Dance)

Retos, Journal Year: 2024, Volume and Issue: 56, P. 280 - 288

Published: April 20, 2024

Introducción. El ejercicio físico mejora la salud psicofísica de los adultos mayores. Sin embargo, existen variables sociodemográficas que favorecen o dificultan práctica deportiva han sido escasamente investigadas (educación, ingresos, género y estado civil), ni se ha prestado atención a estas en relación con diferentes deportes practicados (gimnasia, actividades acuáticas, yoga, pilates danza). Objetivo. Por ello, el objetivo este estudio conocer perfil sociodemográfico mayores realizan algún deporte. Procedimiento. Se utilizó escala calidad vida CUBRECAVI un cuestionario una muestra 358 personas 60 años (M = 69,66, DT 4,74). Resultados. Los resultados mostrado entre hacen gimnasia hay más participantes tienen menor cualificación académica (p < 0,001), bajos ingresos 0,001); mujeres 0,003); solteros divorciados danza mayor proporción otras 0,004). Conclusiones. En conclusión, actividad practicada por está relacionada nivel educación tienen, perciben, su civil. Palabras clave: Personas mayores; envejecimiento; deporte, física; diferencias socioeconómicas; educación; ingresos; género. Abstract. Introduction: Physical exercise enhances the psychophysical well-being of older adults. However, sociodemographic that may either facilitate or impede engagement in physical activities, such as education, income, gender, and marital status, have been insufficiently explored. Furthermore, limited attention has given to these concerning specific including gymnastics, aquatic pilates, dance. Objective: The aim this study is delineate profile physically active adults based on type activity they participate in. Procedure: A sample individuals aged over years 69.66, SD 4.74) participated study, utilizing Quality Life Scale questionnaire, specifically CUBRECAVI. Results: findings indicate engaged gymnastics are more likely possess lower academic qualifications .001), income be women .003). Additionally, single divorced dance activities at higher rate compared other .004).Conclusion: In summary, choice among associated with their educational level, status. Keywords: adults; aging; activity; sport; socioeconomic differences; education; income; gender.

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Technology Use Among Older Adults and Their Caregivers: Cross-Sectional Survey Study

JMIR Aging, Journal Year: 2024, Volume and Issue: 7, P. e50759 - e50759

Published: May 1, 2024

Abstract Background Informal caregivers are called upon to provide substantial care, but more needs be known about technology use among older adult and caregiver dyads. Objective This study described adults their caregivers, explored potential correlates of use, highlighted implications for practice. Methods A cross-sectional survey was conducted unpaid (n=486). Primary outcomes were self-reported (devices functions) oldest care recipient. The concordance recipients also examined. Multivariable regression models separately recipients. Results Greater proportions used all examined technologies, except the medication alerts or tracking function, than Caregivers an average 3.4 devices 4.2 functions, compared 1.8 1.6 functions by Among younger age, higher income, education associated with ( P <.05). recipients, not having cognitive dysfunction, caregiver’s Conclusions Understanding patterns device adoption across diverse recipient populations is increasingly important enhancing geriatric care. Findings can guide recommendations appropriate interventions help providers communicate share information effectively patients caregivers.

Language: Английский

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The role and mechanism of gut-lung axis mediated bidirectional communication in the occurrence and development of chronic obstructive pulmonary disease

Gut Microbes, Journal Year: 2024, Volume and Issue: 16(1)

Published: Oct. 24, 2024

The current studies have shown that the occurrence and development of chronic obstructive pulmonary disease (COPD) are closely related to changes in gut health its microenvironment, even some diseases significant clinical correlation with COPD. dysbiosis microbiota observed COPD patients also suggests a potential bidirectional interaction between lung. Communication lung may occur through circulating inflammatory cells, microbial metabolites, mediators, but mechanism communication is still under study. Therefore, more research needed this area. In review, we summarize recent animal models on role gut-lung axis mechanisms, so as provide ideas for further field. addition, summarized negative effects medication risk factors proposed prevention treatment strategies.

Language: Английский

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Enhancing emergency care for older persons: the role and impact of the electronic Frailty Index

GeroScience, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 13, 2025

Abstract As the elderly population expands, enhancing emergency department (ED) care by assessing frailty becomes increasingly vital. To address this, we developed a novel electronic Frailty Index (eFI) from ED health records, specifically designed to assess and predict hospitalization, in-hospital mortality, ICU admissions, 30-day readmissions. This retrospective, single-center study included patients 65 years old or older who presented of IRCCS Humanitas Research Hospital in Milan, Italy, between January 2015 December 2019. was assessed using (eFI), based on cumulative deficit model, incorporating 45 deficits quantify frailty. Patients were divided into four quartiles eFI scores explore association levels adverse outcomes, including admission, readmission. The 21,537 (mean age 77.4, 50.7% males). median score 0.16. Hospitalization rates rose significantly with frailty, 20% least frail quartile 43% most frail. Similarly, mortality admissions increased markedly higher scores, climbing 0.44 5.0% across quartiles. readmission 9.9 19.8%. For every 0.01 increase score, odds ( P < 0.0001). Specifically, adjusted ratios (OR) for 3.55, 14.15, 4.70, 2.22, respectively 0.0001), compared quartile. integration settings can enable more precise risk stratification resource allocation, improving patient management healthcare delivery persons these urgent contexts.

Language: Английский

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Socioeconomic status moderate the relationship between mental health literacy, social participation, and active aging among Chinese older adults: evidence from a moderated network analysis

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 13, 2025

Language: Английский

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Morality and Ethical Challenges in Philanthropy—Initiating a Spark and Illuminating Future Research Directions

Published: Jan. 19, 2025

Language: Английский

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Motives of Peer Volunteers Aged Over 50 in Physical Activity Programs: A Scoping Review

Journal of Aging and Physical Activity, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 11

Published: Jan. 1, 2025

Peer-volunteering schemes can facilitate health improvement via increasing physical activity levels. Understanding what motivates peer volunteers is valuable for the feasibility of volunteering schemes. This scoping review aims to explore motivations aged over 50 who participate in programs that promote activity. Four databases were searched March 2023 with no date restrictions. The inclusion criteria adults years age, experience peer-volunteering schemes, assessed volunteer motivation, and uses English language. Nine studies included (252 participants, 54–85) Peer-volunteer characteristics extracted from papers. An inductive thematic analysis approach was taken analyze motivation data. themes then mapped onto theoretical constructs motivation. Three emerged could enable us better design peer-volunteer recruitment strategies: altruistic (giving back), personal (meeting goals), past (helping others overcome experienced barriers). suggested fall line mechanisms by psychological theories such as social cognitive self-determination theories. To improve uptake retention, appropriate frameworks should be employed inform content future interventions ensure will have their met.

Language: Английский

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