Exploring the gut microbiome: A potential biomarker for cancer diagnosis, prognosis, and therapy DOI

Eui-Jeong Han,

Ji‐Seon Ahn, Yu-Jin Choi

et al.

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Journal Year: 2024, Volume and Issue: unknown, P. 189251 - 189251

Published: Dec. 1, 2024

Language: Английский

Lower Respiratory Microbiome Dysbiosis is Associated with Poor Prognosis in Acute Severe Lower Respiratory Tract Infection DOI
Minghua Zhan, Hongbin Chen, Zhuangzhuang Li

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Gastrointestinal (GI)-Lung-Brain Axis DOI
Catalina Bazacliu,

Josep Roig,

Josef Neu

et al.

Seminars in Fetal and Neonatal Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 101639 - 101639

Published: April 1, 2025

Language: Английский

Citations

0
Engineering inhalable nanomedicines to navigate lung barriers for effective pulmonary fibrosis therapy DOI
Junlan Lu, Lin Sun, Mei Dong

et al.

Nano Today, Journal Year: 2025, Volume and Issue: 64, P. 102778 - 102778

Published: May 2, 2025

Language: Английский

Citations

0
Xuanfei Baidu Decoction ameliorates bleomycin-elicited idiopathic pulmonary fibrosis in mice by regulating the lung-gut crosstalk via IFNγ/STAT1/STAT3 axis DOI

Mengjie Jia,

Yiman Liu, Jia Liu

et al.

Phytomedicine, Journal Year: 2024, Volume and Issue: 135, P. 155997 - 155997

Published: Sept. 2, 2024

Language: Английский

Citations

2
State of the art: Alternative overlap syndrome—asthma and obstructive sleep apnea DOI
Octavian C. Ioachimescu

Journal of Investigative Medicine, Journal Year: 2024, Volume and Issue: 72(7), P. 589 - 619

Published: May 8, 2024

In the general population, Bronchial Asthma (BA) and Obstructive Sleep Apnea (OSA) are among most prevalent chronic respiratory disorders. Significant epidemiologic connections complex pathogenetic pathways link these disorders via interactions at genetic, epigenetic, environmental levels. The coexistence of BA OSA in an individual likely represents a distinct syndrome, that is, collection clinical manifestations attributable to several mechanisms pathobiological signatures. To avoid terminological confusion, this association has been named alternative overlap syndrome (vs represented by obstructive pulmonary disease-OSA association). This comprehensive review summarizes complex, often bidirectional links between constituents syndrome. Cross-sectional, or clinic-based studies unlikely elucidate causality directionality relationships. Even longitudinal epidemiological evaluations cohorts developing over time OSA, during follow-up cannot exclude factors causal influence other known unknown mediators. As such, lot pathophysiological described here have suggestive evidence, biological plausibility, potential actual directionality. By showcasing existing evidence current knowledge gaps, hope is deliberate, focused, collaborative efforts near-future will be geared toward opportunities shine light on unknowns accelerate discovery field health, care, education, research, scholarly endeavors.

Language: Английский

Citations

1
Gut microbes coordinate pulmonary immunity DOI

Chryso Christodoulou,

Thomas B. Clarke

Proceedings of the National Academy of Sciences, Journal Year: 2024, Volume and Issue: 121(25)

Published: June 6, 2024

Language: Английский

Citations

1
Adjuvant-independent airway sensitization and infection mouse models leading to allergic asthma DOI Creative Commons
Mariem Radhouani, Philipp Starkl

Frontiers in Allergy, Journal Year: 2024, Volume and Issue: 5

Published: Aug. 2, 2024

Asthma is a chronic respiratory disease of global importance. Mouse models allergic asthma have been instrumental in advancing research and novel therapeutic strategies for patients. The application relevant allergens physiological routes exposure such has led to valuable insights into the complexities onset development as well key mechanisms. Furthermore, environmental microbial exposures infections shown play fundamental part pathogenesis alter outcome. In this review, we delve mouse explore literature reports on most significant interplays between with relevance human disease.

Language: Английский

Citations

1
Integrating respiratory microbiome and host immune response through machine learning for respiratory tract infection diagnosis DOI Creative Commons
Hongbin Chen, Tianqi Qi, Siyu Guo

et al.

npj Biofilms and Microbiomes, Journal Year: 2024, Volume and Issue: 10(1)

Published: Sept. 12, 2024

Language: Английский

Citations

1
Causal roles of skin and gut microbiota in skin appendage disorders suggested by genetic study DOI Creative Commons

Yuhang Zhu,

Wanguo Liu,

Mei Wang

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 10, 2024

There is evidence from observational studies that human microbiota linked to skin appendage Disorders (SADs). Nevertheless, the causal association between and SADs yet be fully clarified.

Language: Английский

Citations

0
Potential of gut microbiota metabolites in treating COPD: network pharmacology and Mendelian randomization approaches DOI Creative Commons
Zhenghua Cao,

Shengkun Zhao,

Tong Wu

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 25, 2024

The gut microbiota and its metabolites exert a significant influence on COPD, yet the underlying mechanisms remain elusive. We aim to holistically evaluate role of in COPD through network pharmacology Mendelian randomization approaches.

Language: Английский

Citations

0