Gut Mycobiome: Latest Findings and Current Knowledge Regarding Its Significance in Human Health and Disease DOI Creative Commons
Bogdan Gașpar,

Oana Alexandra Roşu,

Robert Mihai Enache

et al.

Journal of Fungi, Journal Year: 2025, Volume and Issue: 11(5), P. 333 - 333

Published: April 22, 2025

The gut mycobiome, the fungal component of microbiota, plays a crucial role in health and disease. Although fungi represent small fraction ecosystem, they influence immune responses, homeostasis, disease progression. mycobiome’s composition varies with age, diet, host factors, its imbalance has been linked to conditions such as inflammatory bowel (IBD) metabolic disorders. Advances sequencing have expanded our understanding fungi, but challenges remain due methodological limitations high variability between individuals. Emerging therapeutic strategies, including antifungals, probiotics, fecal microbiota transplantation, dietary interventions, show promise require further study. This review highlights recent discoveries on interactions bacteria, disease, potential clinical applications. A deeper contributions will help develop targeted microbiome-based therapies.

Language: Английский

Using synthetic biology to understand the gut-brain axis DOI Creative Commons
Angela Cesaro, Esther Broset, Gregory J. Salimando

et al.

Cell Reports Physical Science, Journal Year: 2025, Volume and Issue: unknown, P. 102458 - 102458

Published: Feb. 1, 2025

Language: Английский

Citations

1
Gut Mycobiome: Latest Findings and Current Knowledge Regarding Its Significance in Human Health and Disease DOI Creative Commons
Bogdan Gașpar,

Oana Alexandra Roşu,

Robert Mihai Enache

et al.

Journal of Fungi, Journal Year: 2025, Volume and Issue: 11(5), P. 333 - 333

Published: April 22, 2025

The gut mycobiome, the fungal component of microbiota, plays a crucial role in health and disease. Although fungi represent small fraction ecosystem, they influence immune responses, homeostasis, disease progression. mycobiome’s composition varies with age, diet, host factors, its imbalance has been linked to conditions such as inflammatory bowel (IBD) metabolic disorders. Advances sequencing have expanded our understanding fungi, but challenges remain due methodological limitations high variability between individuals. Emerging therapeutic strategies, including antifungals, probiotics, fecal microbiota transplantation, dietary interventions, show promise require further study. This review highlights recent discoveries on interactions bacteria, disease, potential clinical applications. A deeper contributions will help develop targeted microbiome-based therapies.

Language: Английский

Citations

0