Alpha-Linolenic Acid and Cardiovascular Events: A Narrative Review DOI Open Access

C Bertoni,

Martina Abodi, Veronica D’Oria

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(18), P. 14319 - 14319

Published: Sept. 20, 2023

Cardiovascular diseases (CVDs) represent the leading cause of global mortality with 1.7 million deaths a year. One alternative systems to drug therapy minimize risk CVDs is represented by alpha-linolenic acid (ALA), an essential fatty omega-3 series, known for its cholesterol-lowering effect. The main purpose this review analyze effects ALA and investigate relevant omega-6/omega-3 ratio in order maintain functionally beneficial effects. Concerning lipid-lowering preventive effects, may favorably affect values LDL-C triglycerides both adult pediatric populations. Furthermore, has shown protective against hypertension, contributing balancing blood pressure through customary diet. According 2009 EFSA statement, dietary contribute reducing CVDs, thanks anti-hypertensive, anti-atherosclerotic cardioprotective

Language: Английский

The composition and physico-chemical properties of human milk: A review DOI Creative Commons
Fanyu Meng, T. Uniacke‐Lowe, C. Anthony Ryan

et al.

Trends in Food Science & Technology, Journal Year: 2021, Volume and Issue: 112, P. 608 - 621

Published: March 28, 2021

Human milk is recommended as the optimal source of nutrition for babies up to six months age, it provides individualized, specific and abundant nutritional compounds, well immunological protection. Currently, there wide interest in studying human because this key role, identification biologically active compounds. In addition, banks play an important role supplying donor infants, especially premature hospitals, which involves processing storage such milk. This review summarises recent studies on macronutrients milk, including their structure, levels, influencing factors, contributions health benefits infants. Physico-chemical properties are also reviewed, pH, colour, stability casein micelles, size zeta-potential fat globules, heat stability, freeze-thaw effect, dehydration phase separation, impact preservation processes these. The levels factors that influence these, lactation gestational ongoing research topics. Studies physicochemical some components, caseins, comparatively few, has mainly focused bioactive peptides, globule membrane oligosaccharides. Processing applied effects these methods retention nutrients use hospitals must be considered. Some physico-chemical properties, physical may possible indicators quality.

Language: Английский

Citations

63

Potential Benefits of Bovine Colostrum in Pediatric Nutrition and Health DOI
Per Torp Sangild, Caitlin Vonderohe, Valeria Meléndez Hebib

et al.

Nutrients, Journal Year: 2021, Volume and Issue: 13(8), P. 2551 - 2551

Published: July 26, 2021

Bovine colostrum (BC), the first milk produced from cows after parturition, is increasingly used as a nutritional supplement to promote gut function and health in other species, including humans. The high levels of whey casein proteins, immunoglobulins (Igs), bioactives BC are adapted meet needs newborn calves. However, supplementation may improve outcomes across especially when immune functions immature early life. We provide review composition its effects infants children selected diseases (diarrhea, infection, growth-failure, preterm birth, necrotizing enterocolitis (NEC), short-bowel syndrome, mucositis). Human trials animal studies (mainly piglets) reviewed assess scientific evidence whether safe effective antimicrobial immunomodulatory that reduces clinical complications related infections, disorders. Studies animals suggest should be supplemented at an optimal age, time, level both effective. Exclusive feeding not recommended for because imbalances relative human milk. On hand, adverse effects, allergies intolerance, appear unlikely provided within normal nutrition guidelines children. Larger infant populations needed more benefits patients with addition or formula. Igs bioactive factors work synergy, making it critical preserve bioactivity gentle processing pasteurization methods. has potential become several pediatric subpopulations.

Language: Английский

Citations

62

Psychosocial stress and cortisol stress reactivity predict breast milk composition DOI Creative Commons
Anna Ziomkiewicz, Magdalena Babiszewska, Anna Apanasewicz

et al.

Scientific Reports, Journal Year: 2021, Volume and Issue: 11(1)

Published: June 2, 2021

We studied a sample of 146 Polish, exclusively breastfeeding mothers and their healthy born on time infants to explore the effect perinatal psychosocial stress breast milk composition. Maternal was assessed using Recent Life Changes Questionnaire summarizing stressful events from previous six months. Stress reactivity determined by administering cold pressor test measuring cortisol in saliva samples taken during test. Breast measure energy, protein, fat, lactose, fatty acid content. Analyses revealed that positively associated with fat long-chain unsaturated acids negatively lactose. Perinatal affected energy density, as well medium-chain saturated milk. These results, together studies, advocate monitoring maternal psychological status peripartum promote infant nutrition.

Language: Английский

Citations

61

Human milk fatty acid composition and its association with maternal blood and adipose tissue fatty acid content in a cohort of women from Europe DOI Creative Commons
Francesca Giuffrida, Mathilde Fleith,

Amélie Goyer

et al.

European Journal of Nutrition, Journal Year: 2022, Volume and Issue: 61(4), P. 2167 - 2182

Published: Jan. 24, 2022

Human milk (HM) composition is influenced by factors, like maternal diet and body stores, among other factors. For evaluating the influence of fatty acid (FA) status on FA composition, correlation between content in HM plasma, erythrocytes, adipose tissue was investigated.

Language: Английский

Citations

43

Alpha-Linolenic Acid and Cardiovascular Events: A Narrative Review DOI Open Access

C Bertoni,

Martina Abodi, Veronica D’Oria

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(18), P. 14319 - 14319

Published: Sept. 20, 2023

Cardiovascular diseases (CVDs) represent the leading cause of global mortality with 1.7 million deaths a year. One alternative systems to drug therapy minimize risk CVDs is represented by alpha-linolenic acid (ALA), an essential fatty omega-3 series, known for its cholesterol-lowering effect. The main purpose this review analyze effects ALA and investigate relevant omega-6/omega-3 ratio in order maintain functionally beneficial effects. Concerning lipid-lowering preventive effects, may favorably affect values LDL-C triglycerides both adult pediatric populations. Furthermore, has shown protective against hypertension, contributing balancing blood pressure through customary diet. According 2009 EFSA statement, dietary contribute reducing CVDs, thanks anti-hypertensive, anti-atherosclerotic cardioprotective

Language: Английский

Citations

23