Abnormal mu rhythm state-related cortical and corticospinal responses in chronic stroke DOI Creative Commons
Miles Wischnewski,

Zachary Haigh,

Taylor Berger

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 15, 2024

Abstract The motor cortex’s activity is state-dependent. Specifically, the sensorimotor mu rhythm phase relates to fluctuating levels of primary cortex (M1) excitability, previously demonstrated in young and healthy volunteers. However, it unknown whether this observation generalizable individuals with brain lesions after a stroke. We investigated relationship between cortical excitability by combining real-time processing electroencephalography (EEG) signals transcranial magnetic stimulation (TMS) M1. In 11 chronic subcortical stroke survivors 12 similar-aged volunteers, we applied TMS M1 at peak, falling, trough, rising oscillation. As outcome measures, M1-to-muscle measuring motor-evoked potentials (MEPs) local activation TMS-evoked (TEPs). found that older volunteers shows phase-dependency similar adults. That is, MEPs were increased decreased trough peak rhythm, respectively. stronger stroke-related symptoms showed preference. Further, was abolished activity, as measured EEG, stroke-affected hemisphere, contrast non-affected hemisphere well either Altogether, these results shed light on state-dependency Our indicate strength preference responses could severity impairment. These enable development improved paradigms for recovery impairment

Language: Английский

Transcranial Direct Current Stimulation to Ameliorate Post-Stroke Cognitive Impairment DOI Creative Commons
Kelly L. Sloane, Roy H. Hamilton

Brain Sciences, Journal Year: 2024, Volume and Issue: 14(6), P. 614 - 614

Published: June 19, 2024

Post-stroke cognitive impairment is a common and disabling condition with few effective therapeutic options. After stroke, neural reorganization other neuroplastic processes occur in response to ischemic injury, which can result clinical improvement through spontaneous recovery. Neuromodulation transcranial direct current stimulation (tDCS) promising intervention augment underlying neuroplasticity order improve function. This form of neuromodulation leverages mechanisms post-stroke optimize In this review, we summarize the state neurorehabilitation post-stroke, practical features tDCS, its uses stroke-related across domains, special considerations for use tDCS patient population.

Language: Английский

Citations

2
Using Dual-Target rTMS, Single-Target rTMS, or Sham rTMS on Post-Stroke Cognitive Impairment DOI Creative Commons

Bingshan Xu,

Chunrong Lin,

Yiwen Wang

et al.

Journal of Integrative Neuroscience, Journal Year: 2024, Volume and Issue: 23(8)

Published: Aug. 23, 2024

The clinical application of 10 Hz repetitive transcranil magnetic stimulation (rTMS) remains limited despite its demonstrated effectiveness in enhancing cortical excitability and improving cognitive function. present study used a novel stimulus target [left dorsolateral prefrontal cortex + primary motor cortex] to facilitate the enhancement function through bidirectional promotion functions; Methods: Post-stroke impairment patients (

Language: Английский

Citations

2
Noninvasive brain stimulation to improve motor outcomes after stroke DOI

Emma C.J. Savelon,

Harry T. Jordan, Cathy M. Stinear

et al.

Current Opinion in Neurology, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 2, 2024

Purpose of review This highlights recent developments in noninvasive brain stimulation (NIBS) techniques and applications for improving motor outcomes after stroke. Two promising areas development relate to deep neuromodulation the use single-pulse transcranial magnetic (TMS) within a prediction tool predicting upper limb outcome individual patients. Recent findings Systematic reviews highlight inconsistent effect sizes interventional NIBS stroke, as well limited evidence supporting interhemispheric competition model. To improve therapeutic efficacy NIBS, studies have leveraged metaplasticity priming approaches. Transcranial temporal interference (tTIS) low-intensity focused ultrasound (LIFUS) are emerging with potential modulating deeper structures, which may hold promise stroke neurorehabilitation. Additionally, evoked (MEP) status obtained TMS is prognostic biomarker that could be used tailor Summary Trials improved by applying more targeted manner. achieved taking advantage can using biomarkers structural functional reserve stratify patients, recruiting patients homogeneous time windows.

Language: Английский

Citations

2
Facilitating Corticomotor Excitability of the Contralesional Hemisphere Using Non-Invasive Brain Stimulation to Improve Upper Limb Motor Recovery from Stroke—A Scoping Review DOI Open Access
Pui Kit Tam, Nicodemus Oey, Ning Tang

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(15), P. 4420 - 4420

Published: July 28, 2024

Upper limb weakness following stroke poses a significant global psychosocial and economic burden. Non-invasive brain stimulation (NIBS) is potential adjunctive treatment in rehabilitation. However, traditional approaches to rebalance interhemispheric inhibition may not be effective for all patients. The supportive role of the contralesional hemisphere recovery upper motor function has been supported by animal clinical studies, particularly those with severe strokes. This review aims provide an overview facilitation post-stroke recovery. While more studies are required predict responses inform choice NIBS approach, offer new hope patients whom rehabilitation have failed.

Language: Английский

Citations

1
Clinical implementation, barriers, and unmet needs of rTMS and neuro-navigation systems in stroke rehabilitation: a nationwide survey in South Korea DOI Creative Commons

Ga Hui Yu,

Chul Min Park, Myeong Geun Jeong

et al.

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: July 30, 2024

Objective The objective of this study was to determine the implementation, clinical barriers, and unmet needs repetitive transcranial magnetic stimulation (rTMS) neuro-navigation systems for stroke rehabilitation. Design We employed a nationwide survey via Google Forms (web mobile) consisting 36 questions across rTMS systems, focusing on their perceptions, in recovery. targeted physiatrists registered Korean Society Neuro-rehabilitation rehabilitation hospitals South Korea. Results Of 1,129 surveys distributed, 122 responses were analyzed. Most respondents acknowledged effectiveness treating post-stroke impairments; however, they highlighted significant standardized treatment protocols, guidelines, education, device usability, insurance coverage. Unmet also identified; only 7.4% currently used such despite acknowledging potential enhance accuracy. Seventy percent identified lack prescription coverage, time errors preparation, cost as barriers adoption systems. Conclusion Despite recognition rehabilitation, there is considerable gap between research evidence practice. Addressing these challenges, establishing advancing accessible could significantly application rTMS, offering more personalized, effective modality

Language: Английский

Citations

1
rTMS for Poststroke Pusher Syndrome: A Randomized, Patient-Blinded Controlled Clinical Trial DOI
Lijiao Meng,

Yanlei Ge,

Raymond C. C. Tsang

et al.

Neurorehabilitation and neural repair, Journal Year: 2024, Volume and Issue: 38(9), P. 670 - 679

Published: Aug. 5, 2024

Patients with poststroke pusher syndrome (PS) require longer duration of rehabilitation and more supplemental care after discharge. Effective treatment PS remains a challenge. The role repetitive transcranial magnetic stimulation (rTMS) for has not been examined.

Language: Английский

Citations

1
Effect of Repetitive Transcranial Magnetic Stimulation on Post-Stroke Comorbid Cognitive Impairment and Depression: A Randomized Controlled Trial DOI

Kuide Li,

Dan Mo, Qian Yu

et al.

Journal of Alzheimer s Disease, Journal Year: 2024, Volume and Issue: 101(1), P. 337 - 352

Published: Aug. 20, 2024

There are currently no uniform treatments for post-stroke comorbid cognitive impairment and depression (PSCCID).

Language: Английский

Citations

1
Global research trends in transcranial magnetic stimulation for stroke (1994–2023): promising, yet requiring further practice DOI Creative Commons
Xinyu Li,

Rong Hu,

Tian-xiao Lou

et al.

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 29, 2024

Background Scholars have been committed to investigating stroke rehabilitation strategies over many years. Since its invention, transcranial magnetic stimulation (TMS) has increasingly employed in contemporary research. Evidence shown the significant potential of TMS research and treatment. Objective This article reviews conducted on use from 1994 2023. study applied bibliometric analysis delineate current landscape anticipate future hotspots. Method The utilized Web Science Core Collection retrieve acquire literature data. Various software tools, including VOSviewer (version 1.6.19), CiteSpace 6.3.R1), Scimago Graphica 1.0.36), WPS 11572), were used for data visualization. review included analyses countries, institutions, authors, journals, articles, keywords. Results A total 3,425 articles collected. top three countries terms publication output United States (953 articles), China (546 Germany (424 articles). also had highest citation counts (56,764 citations), followed by (35,211 citations) Kingdom (32,383 citations). institutions based number publications Harvard University with 138 Auckland 81 College London 80 articles. most prolific authors Abo, Masahiro 54 Fregni, Felipe 53 Pascual-Leone, Alvaro 50 journals count Neurorehabilitation Neural Repair 139 Clinical Neurophysiology 128 Frontiers Neurology 110 frequently occurring keywords (1,275 occurrences), (1,119 (420 occurrences). Conclusion application is rapidly gaining momentum, USA leading publications. Prominent such as London, show collaborative key areas focus include post-stroke cognitive impairment, aphasia, dysphagia, which are expected remain hotspots Future should involve large-scale, randomized, controlled trials these fields. Additionally, identifying more effective combined therapies rTMS be a priority.

Language: Английский

Citations

1
Repetitive Transcranial Magnetic Stimulation for Motor Recovery After Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials With Low Risk of Bias DOI
John J.Y. Zhang,

Jensen Ang,

Seyed Ehsan Saffari

et al.

Neuromodulation Technology at the Neural Interface, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

1
Research trends and hotspots of post-stroke upper limb dysfunction: a bibliometric and visualization analysis DOI Creative Commons
Qingqing Tang, Xinyue Yang, Mengmeng Sun

et al.

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 2, 2024

Background The global prevalence of stroke has been increasing. Motor dysfunction is observed in approximately 55 to 75% patients, with upper limb impairment affecting around 85% them. Following dysfunction, the body’s recovery time not only slower compared lower limbs, but restoration its fine motor skills significantly more challenging, greatly impacting daily lives patients. Consequently, there an increasing urgency for study on function stroke. Methods A search was conducted Web Science Core Collection: Citation Index Expanded (SCI-Expanded) database material published from January 1, 2004 December 31, 2023. We included all relevant literature reports and analysis annual publications, countries/regions, institutions, journals, co-cited references, keywords using software packages CiteSpace, VOSviewer, Bibliometrix R. Next, we succinctly outlined research trends hotspots post-stroke dysfunction. Results This comprised 1,938 articles 1,897 354 53 countries or regions. yearly rise production publications noted. United States foremost nation issue. Northwestern University most amounts papers other institutions. journal Neurorehabilitation Neural Repair a highly significant publication this field, Catherine E. Lang serving as principal author. majority most-cited references focus subjects such reliability validity assessment instruments, RCT therapies, systematic reviews, meta-analyses. intervention measures primarily comprise three types high-frequency phrases that are related, determined by keyword analysis: intelligent rehabilitation, physical factor therapy, occupational therapy. Current areas include randomized clinical trials, neurorehabilitation, robot-assisted Conclusion shown growing interest studying assessment, virtual reality, brain-computer interface, telerehabilitation, cortical reorganisation, neural plasticity. These topics have become popular expected be future research.

Language: Английский

Citations

1