Extent and Topography of Subretinal Drusenoid Deposits Associate With Rod-Mediated Vision in Aging and AMD: ALSTAR2 Baseline
Lukas Goerdt,
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Mohymina Amjad,
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Thomas A. Swain
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et al.
Investigative Ophthalmology & Visual Science,
Journal Year:
2024,
Volume and Issue:
65(10), P. 25 - 25
Published: Aug. 20, 2024
In
AMD,
rod-mediated
dark
adaptation
(RMDA)
at
5°
eccentricity
is
slower
in
eyes
with
subretinal
drusenoid
deposits
(SDDs)
than
without.
Here
we
quantified
SDD
burden
using
supervised
deep
learning
for
comparison
to
vision
and
photoreceptor
topography.
Language: Английский
Quantitative assessment of retinochoroidal microvasculature in patients with carotid artery stenosis using OCT angiography
Shiqiang Li,
No information about this author
Wenjuan Zhao,
No information about this author
Tianzi Jian
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et al.
Photodiagnosis and Photodynamic Therapy,
Journal Year:
2024,
Volume and Issue:
46, P. 104082 - 104082
Published: April 1, 2024
To
investigate
the
alterations
in
retinochoroidal
parameters
measured
by
optical
coherence
tomography
(OCT)
and
OCT
angiography
(OCTA)
patients
with
carotid
artery
stenosis
(CAS)
assess
their
associations
digital
subtraction
(DSA)
data.
This
study
enrolled
diagnosed
CAS
age-matched
healthy
controls.
Both
groups
underwent
OCTA
examinations.
DSA
assessment
of
were
performed
only
group.
The
evaluated
various
from
OCTA,
including
linear
vessel
density
(LVD),
foveal
avascular
zone
(FAZ),
choroidal
thickness
(ChT),
retinal
nerve
fiber
layer
(RNFL)
thickness.
DSA-derived
measures
included
cervical
segment
(C1)
diameter,
cavernous
(C4)
percentage,
ophthalmic
(OA)
filling
time,
C1-OA
residual
stenosis.
A
total
42
eyes
30
60
controls
included.
Patients
displayed
significantly
decreased
LVD
compared
to
(p
<
0.001).
Additionally,
group
had
thinner
choroid
RNFL
=
0.047
p
0.001,
respectively).
Macular
negatively
correlated
both
percentage
time
0.010
0.014,
In
who
stenting,
preoperative
ChT
(Pearson
r
-0.480,
0.020).
provide
a
quantitative
microstructural
changes
associated
CAS,
suggesting
potential
for
noninvasive
evaluation
disease.
might
contribute
prevention
irreversible
ocular
complications
early
detection
CAS.
Furthermore,
may
not
aid
diagnosing
more
reliably
but
also
offer
prognostic
information.
Language: Английский
Dissecting the Biological Complexity of Age-Related Macular Degeneration: Is it One Disease, Multiple Separate Diseases, or a Spectrum?
Experimental Eye Research,
Journal Year:
2025,
Volume and Issue:
254, P. 110304 - 110304
Published: Feb. 19, 2025
Language: Английский
Basic science observations link subretinal drusenoid deposit formation to retinal pigment epithelial hypoxia
Eye,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 13, 2024
Language: Английский
AI in the clinical management of GA: A novel therapeutic universe requires novel tools
Progress in Retinal and Eye Research,
Journal Year:
2024,
Volume and Issue:
unknown, P. 101305 - 101305
Published: Sept. 1, 2024
Language: Английский
A cell culture system for RPE hypoxia, a physiologic stressor relevant to AMD deposit formation
Eye,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 13, 2024
Language: Английский
Short-Term Effect of Stimulating the Pterygopalatine Ganglion Via Electroacupuncture on Choroidal Structure in Human Subjects
Xiehe Kong,
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Guang Yang,
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Yaojiani Cao
No information about this author
et al.
Translational Vision Science & Technology,
Journal Year:
2024,
Volume and Issue:
13(10), P. 26 - 26
Published: Oct. 16, 2024
Choroidal
dysfunction
is
implicated
in
various
ocular
pathologies.
The
parasympathetic
pterygopalatine
ganglion
(PPG)
innervates
orbital
vessels
supplying
the
choroid.
While
PPG
stimulation
has
been
shown
to
dilate
cerebral
blood
flow,
its
effects
on
choroid,
particularly
human
subjects,
require
further
elucidation.
This
study
aimed
investigate
short-term
influence
of
via
electroacupuncture
choroidal
structure.
Language: Английский