Breast Cancer Statistics in Korea, 2019 DOI Creative Commons
Jung Eun Choi, Zisun Kim, Chan Sub Park

et al.

Journal of Breast Cancer, Journal Year: 2023, Volume and Issue: 26(3), P. 207 - 207

Published: Jan. 1, 2023

This article provides an annual update of Korean breast cancer statistics, including the incidence, tumor stage, type surgical treatment, and mortality. The data was collected from Breast Cancer Society registry system Central Registry. In 2019, 29,729 women were newly diagnosed with cancer. has continued to increase in incidence since 2002 been most common 2019. Of cases 24,820 (83.5%) invasive carcinomas, 4,909 (16.5%) carcinoma situ. median age 52.8 years, commonly group 40-49 years. number patients who have undergone conserving surgery 2016, 68.6% undergoing early-stage continues increase, stage 0 or I accounting for 61.6% cases. subtype is hormone receptor-positive human epidermal growth factor receptor 2-negative (63.1%). 5-year relative survival rate 2015 2019 93.6%, 14.3% compared that 1993 1995. report improves our understanding characteristics South Korea.

Language: Английский

Next generation sequencing in cancer research and clinical application DOI Creative Commons
Derek Shyr, Qi Liu

Biological Procedures Online, Journal Year: 2013, Volume and Issue: 15(1)

Published: Feb. 13, 2013

The wide application of next-generation sequencing (NGS), mainly through whole genome, exome and transcriptome sequencing, provides a high-resolution global view the cancer genome. Coupled with powerful bioinformatics tools, NGS promises to revolutionize research, diagnosis therapy. In this paper, we review recent advances in NGS-based genomic research as well clinical application, summarize current integrative oncogenomic projects, resources computational algorithms, discuss challenge future directions sequencing.

Language: Английский

Citations

123

Breast cancer stem cells, heterogeneity, targeting therapies and therapeutic implications DOI
Xiaobin Zeng, Chengxiao Liu, Jie Yao

et al.

Pharmacological Research, Journal Year: 2020, Volume and Issue: 163, P. 105320 - 105320

Published: Nov. 30, 2020

Language: Английский

Citations

118

Molecular Classification of Breast Cancer DOI Creative Commons
Elena Provenzano, Gary A. Ulaner, Suet‐Feung Chin

et al.

PET Clinics, Journal Year: 2018, Volume and Issue: 13(3), P. 325 - 338

Published: May 7, 2018

Language: Английский

Citations

117

Allogeneic tumor cell vaccines DOI Open Access
Sanjay Srivatsan, Jaina M. Patel,

Erica N. Bozeman

et al.

Human Vaccines & Immunotherapeutics, Journal Year: 2013, Volume and Issue: 10(1), P. 52 - 63

Published: Sept. 24, 2013

The high mortality rate associated with cancer and its resistance to conventional treatments such as radiation chemotherapy has led the investigation of a variety anti-cancer immunotherapies. development novel immunotherapies been bolstered by discovery tumor-associated antigens (TAAs), through gene sequencing proteomics. One immunotherapy employs established allogeneic human cell lines induce antitumor immunity in patients TAA presentation. Allogeneic are desirable clinical setting due their ease production availability. This review aims summarize trials tumor various types. To date, have shown limited success potentially extensive degrees inter- intra-tumoral heterogeneity found among patients. However, these results provide guidance for rational design creation more effective use monotherapies or combination other therapies.

Language: Английский

Citations

112

Breast Cancer Statistics in Korea, 2019 DOI Creative Commons
Jung Eun Choi, Zisun Kim, Chan Sub Park

et al.

Journal of Breast Cancer, Journal Year: 2023, Volume and Issue: 26(3), P. 207 - 207

Published: Jan. 1, 2023

This article provides an annual update of Korean breast cancer statistics, including the incidence, tumor stage, type surgical treatment, and mortality. The data was collected from Breast Cancer Society registry system Central Registry. In 2019, 29,729 women were newly diagnosed with cancer. has continued to increase in incidence since 2002 been most common 2019. Of cases 24,820 (83.5%) invasive carcinomas, 4,909 (16.5%) carcinoma situ. median age 52.8 years, commonly group 40-49 years. number patients who have undergone conserving surgery 2016, 68.6% undergoing early-stage continues increase, stage 0 or I accounting for 61.6% cases. subtype is hormone receptor-positive human epidermal growth factor receptor 2-negative (63.1%). 5-year relative survival rate 2015 2019 93.6%, 14.3% compared that 1993 1995. report improves our understanding characteristics South Korea.

Language: Английский

Citations

39