Journal of Ocular Pharmacology and Therapeutics,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 18, 2025
Purpose:
To
evaluate
myopia
progression
in
children
treated
with
0.01%
atropine
eye
drops
compared
controls.
Methods:
Two
longitudinal
cohorts
of
myopic
(atropine
and
control)
were
observed
different
time
periods.
All
had
an
increase
greater
than
-0.50
diopters
(D)
or
axial
length
(AL)
growth
>0.20
mm
the
previous
year.
Patients
examined
at
baseline
every
6
months
for
18
months.
The
primary
outcomes
annual
rate
spherical
equivalent
refractive
error
(SER)
AL.
Response
to
treatment
was
categorized
as
insufficient,
moderate,
good.
Progression
according
age
also
evaluated.
Statistical
significance
defined
P
<
0.05.
Results:
study
included
243
[127
(44.7%)
female;
mean
age,
10.19
±
2.29
years].
group
comprised
158
(65%)
children.
At
months,
(95%
confidence
interval)
change
SER
-0.85
D
(-1.00,
-0.69)
control
-0.73
(-0.85,
-0.61)
(p
=
0.295).
AL
0.41
(0.32,
0.50)
0.33
(0.28,
0.39)
0.160).
Children
aged
<9
years
lowest
percentage
success
[3/21
(27.8%)]
highest
failure
(63.2%)
0.03).
Conclusion:
Atropine
did
not
slow
progression.
Increasing
concentration
combining
optical
treatments
may
be
necessary,
particularly
years,
who
showed
greatest
but
potential
control.
Obesity,
Journal Year:
2022,
Volume and Issue:
30(8), P. 1691 - 1698
Published: July 27, 2022
Abstract
Objective
This
study
analyzed
the
association
between
adolescent
BMI
and
myopia
severity.
Methods
cross‐sectional
comprised
1,359,153
adolescents
who
were
medically
examined
before
mandatory
military
service.
Mild‐to‐moderate
high
defined
based
on
right‐eye
refractive
data.
was
categorized
US
age‐
sex‐matched
percentiles.
Logistic
regression
models
applied
separately
for
women
men
to
estimate
odds
ratios
(ORs)
per
category.
Results
A
total
of
318,712
had
mild‐to‐moderate
23,569
myopia.
Compared
with
low‐normal
(reference
group),
adjusted
ORs
increased
increasing
status,
reaching
1.39
(95%
CI:
1.23‐1.57)
1.73
1.19‐2.51)
severe
obesity,
respectively,
1.19
1.12‐1.27)
1.38
1.14‐1.65)
mild
respectively.
also
higher
in
underweight
(OR
=
1.20;
95%
1.18‐1.23
OR
1.39;
1.30‐1.47)
1.06;
1.03‐1.09
1.12;
1.04‐1.22).
The
overall
size
effect
greater
than
(
p
interaction
<
0.001),
whom
group
obesity
did
not
reach
statistical
significance.
Conclusions
associated
a
J‐shaped
pattern,
being
women.
indicates
that
both
low
are
Ophthalmology and Therapy,
Journal Year:
2024,
Volume and Issue:
13(6), P. 1453 - 1477
Published: May 7, 2024
Myopia
and
its
vision-threatening
complications
present
a
significant
public
health
problem.
This
review
aims
to
provide
an
updated
overview
of
the
multitude
known
emerging
interventions
control
myopia,
including
their
potential
effect,
safety,
costs.
A
systematic
literature
search
three
databases
was
conducted.
Interventions
were
grouped
into
four
categories:
environmental/behavioral
(outdoor
time,
near
work),
pharmacological
(e.g.,
atropine),
optical
(spectacles
contact
lenses),
novel
approaches
such
as
red-light
(RLRL)
therapies.
Review
articles
original
on
randomized
controlled
trials
(RCT)
selected.
From
initial
3224
retrieved
records,
18
reviews
41
reporting
results
from
RCTs
included.
While
there
is
more
evidence
supporting
efficacy
low-dose
atropine
certain
myopia-controlling
lenses
in
slowing
myopia
progression,
about
newer
interventions,
spectacle
defocus
incorporated
multiple
segments
highly
aspheric
lenslets)
limited.
Behavioral
i.e.,
increased
outdoor
seem
effective
for
preventing
onset
if
implemented
successfully
schools
homes.
environmental
spectacles
are
regarded
generally
safe,
lenses,
RLRL
may
be
associated
with
adverse
effects.
All
except
behavioral
change,
tied
moderate
high
expenditures.
Our
suggests
that
recommended
prescribed
basis
accessibility
clinical
practice
patterns,
which
vary
widely
around
world.
Clinical
indicate
short-
medium-term
reducing
progression
various
but
none
have
demonstrated
long-term
effectiveness
adulthood.
There
unmet
need
unified
consensus
strategies
balance
risk
these
methods
personalized
management.
BMJ Open Ophthalmology,
Journal Year:
2024,
Volume and Issue:
9(1), P. e001527 - e001527
Published: Jan. 1, 2024
Objective
Many
children
with
progressive
myopia
are
still
prescribed
single-vision
correction.
An
investigation
into
UK
eyecare
practitioners’
(ECPs)
perceptions
of
management
was
carried
out
to
ascertain
factors
which
may
be
limiting
its
implementation
and
uptake
within
clinical
practice.
Methods
analysis
Online
focus
groups
were
held
ECPs.
Participants
encouraged
discuss
their
knowledge
the
available
options,
perception
how
is
being
delivered
in
any
barriers
ECPs'
prescribing
these
options
The
discussions
transcribed
analysed
thematically.
Results
Focus
41
ECPs
from
primary
secondary
eyecare.
felt
that
provision
variable.
Most
believe
they
have
sufficient
knowledge,
but
a
lack
confidence
decision-making
practical
experience.
Less
experienced
sought
more
definitive
guidance
support
decision-making.
desired
clarity
on
duty
care
obligations
concerned
over
possible
future
litigation
if
had
not
offered,
or
referred
for,
when
indicated.
greatest
barrier
appears
financial—treatment
expensive
uncomfortable
communicating
this
parents.
indicative
systemic
problems
eyecare,
such
as
commercial
pressures,
inadequate
National
Health
Service
funding
poor
public
awareness
paediatric
Conclusion
Myopia
implemented
consistently
across
UK.
To
improve
accessibility,
changes
required
at
multiple
levels,
individual
through
wider
stakeholders
provision.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Jan. 11, 2024
Abstract
Outdoor
exposure
is
considered
the
primary
modifiable
risk
factor
in
preventing
development
of
myopia.
This
effect
thought
to
be
attributed
light-induced
synthesis
and
release
dopamine
retina.
However,
until
recent
years,
there
was
no
objective
quantifiable
method
available
measure
association
between
time
spent
outdoors
It
only
recently
that
conjunctival
ultraviolet
autofluorescence
(CUVAF)
area,
serving
as
a
biomarker
for
sun
exposure,
has
begun
utilized
numerous
studies.
To
provide
comprehensive
summary
relevant
evidence
pertaining
CUVAF
area
myopia
across
different
geographic
regions
age
groups,
systematic
review
meta-analysis
were
conducted.
The
search
encompassed
multiple
databases,
including
MEDLINE,
SCIENCE
DIRECT,
GOOGLE
SCHOLAR,
WEB
OF
SCIENCE,
SCOPUS,
specific
terms
such
"conjunctival
autofluorescence",
"CUVAF",
"UVAF",
"objective
marker
ocular
exposure",
"myopia",
"degenerative
myopia",
"high
myopia".
bibliographic
research
included
papers
published
years
2006
2022.
A
total
4051
records
initially
identified,
after
duplicates
removed,
49
articles
underwent
full-text
review.
Nine
These
studies
covered
outdoor
(Australia,
Europe
India)
with
population
3615
individuals.
They
found
myopes
generally
had
smaller
areas
compared
non-myopes.
confirmed
this,
revealing
statistically
myopic
patients,
mean
difference
−
3.30
mm
2
(95%
CI
5.53;
1.06).
Additionally,
some
showed
positive
correlation
more
larger
areas.
In
time,
patients
reported
less
than
non-myopic
individuals,
3.38
h/week
4.66;
2.09).
Overall,
these
findings
highlight
connection
myopia,
regional
variations
playing
significant
role.
results
this
validate
quantitative
objectively
relation
development.
Children,
Journal Year:
2024,
Volume and Issue:
11(2), P. 139 - 139
Published: Jan. 23, 2024
Background:
Childhood
myopia
represents
a
global
concern
with
increasing
prevalence
in
recent
decades.
Lifestyle
factors
significantly
impact
myopia.
Aim:
To
evaluate
lifestyle
myopic
children
from
metropolitan
area
Europe.
Methods:
This
was
descriptive
study
including
subjects
aged
4–18
years.
Patient
demographic
and
clinical
data
were
collected,
cycloplegic
refraction
spherical
equivalent
(SER)
axial
length
(AL).
In
addition,
questionnaire
on
conducted
between
September
2022
April
2023.
Results:
A
total
of
321
included,
10.72
±
3.05
years,
whom
51.4%
boys,
SER
−2.25
1.9
D
AL
24.54
0.98
mm.
The
mean
age
onset
7.69
59.8%
had
family
history
Those
who
<2
h/day
screen
time
(on
weekdays)
presented
−2
1.91
D,
compared
to
those
>2
h/day,
SER:
−2.50
±1.88
(p
=
0.009).
Children
spent
doing
near
work
after
school
less
(SER:
−1.75
1.83
vs.
−2.75
1.82,
respectively,
p
0.03).
However,
no
significant
association
observed
outdoors
nor
academic
performance
>
0.05).
Conclusions:
Screen
near-work
appear
be
related
Frontiers in Public Health,
Journal Year:
2024,
Volume and Issue:
12
Published: Feb. 22, 2024
Background
Myopia
poses
a
global
health
concern
and
is
influenced
by
both
genetic
environmental
factors.
The
incidence
of
myopia
tends
to
increase
during
infectious
outbreaks,
such
as
the
COVID-19
pandemic.
This
study
examined
screen-time
behaviors
among
Chinese
children
adolescents
investigated
efficacy
artificial
intelligence
(AI)-based
alerts
in
modifying
practices.
Methods
A
cross-sectional
analysis
was
performed
using
data
from
6,716
with
AI-enhanced
tablets
that
monitored
recorded
their
behavior
light
screen
time.
Results
median
daily
time
all
participants
58.82
min.
Among
age
groups,
elementary-school
students
had
longest
time,
which
87.25
min
exceeded
4
h
per
week.
Children
younger
than
2
years
engaged
for
41.84
day.
Learning
accounted
54.88%
participants’
51.03%
(3,390/6,643)
used
1
at
an
average
distance
<50
cm.
posture
alarms
were
triggered
807,355
509,199
times,
respectively.
In
study,
70.65%
tablet
under
illuminance
<300
lux
day
61.11%
<100
night.
ambient
85.19%
4,000
K
color
temperature
Most
incorrect
viewing
habits
(65.49%
distance;
86.48%
posture)
rectified
swiftly
following
AI
notifications
(all
p
<
0.05).
Conclusion
Young
are
increasingly
digital
screens,
school-age
showing
longer
preschoolers.
highlighted
inadequate
lighting
conditions
use.
proved
effective
prompting
users
correct
screen-related
promptly.
F1000Research,
Journal Year:
2025,
Volume and Issue:
13, P. 1318 - 1318
Published: Jan. 6, 2025
Background
One
of
the
most
common
strabismus
types
in
children
is
intermittent
exotropia,
which
predominantly
occurs
between
ages
2
to
4
years.
It
may
affect
visual
development
and
often
coexists
with
refractive
errors.
Unlike
esotropia,
usually
links
hyperopia,
exotropia
might
have
a
different
relationship
errors
thus
lead
myopia.
This
study
will
investigate
prevalence
distribution
challenging
traditionally
held
hyperopia
its
possible
contribution
Methods
In
this
cross-sectional
retrospective
from
August
2021
December
2023,
179
patients
diagnosed
were
recruited
via
an
outpatient
clinic
Najah
Al-Quraishi,
Baghdad,
Iraq.
The
compared
by
autorefractometry
retinoscopy
after
cycloplegic
dilation.
Data
analysis
was
constructed
under
use
IBM
SPSS
V.26
for
determination
emmetropia,
myopia,
prevalence.
Results
Among
patients,
emmetropia
commonly
observed
status,
present
68
(38%).
Low
low
myopia
also
common,
64
40,
respectively.
A
limited
number
had
moderate/high
hyperopia;
detail,
following:
5%
moderate
while
0.5%
suffered
high
myopia;
symmetrically,
hyperopia.
From
data
collected,
trend
emerged
error
symmetric
both
eyes.
Conclusion
Contrasted
prior
conventional
wisdom
about
strabismus,
it
established
greater
exotropia.
findings
call
specific
management
strategies
be
applied
population.
F1000Research,
Journal Year:
2025,
Volume and Issue:
14, P. 39 - 39
Published: Jan. 7, 2025
Background
Approximately
1.6
billion
people
worldwide
are
currently
affected
by
myopia,
with
estimates
suggesting
that
2050,
close
to
half
of
the
global
population
may
experience
this
condition.
Additionally,
prevalence
myopia
has
been
increasing
in
Trinidad,
rates
ranging
from
21.5%
46%.
A
study
conducted
determine
better
patients’
and
students’
levels
knowledge,
attitudes,
preferences
toward
management
Trinidad.
Methods
This
cross-sectional
evaluated
for
among
a
sample
323
participants,
including
patients
university
students
Trinidad
Tobago,
aged
18-40.
Participants
were
randomly
selected,
data
gathered
using
structured
questionnaire
administered
through
telephone
interviews
emailed
students.
Descriptive
statistics
inferential
analyses,
ANOVA
T-tests,
applied
identify
significant
associations,
p-value
threshold
less
than
0.05
considered
statistically
significant.
Results
total
317
participants
examined,
resulting
response
rate
98.1%.
The
average
knowledge
score
was
12
out
25.
slight
difference
observed
scores
males,
0.052.
results
also
indicated
majority
had
good
attitude
(21.6
30)
management.
Age
gender
negligible
negative
correlation
(with
coefficient
-0.022
0.692,
respectively)
preference.
Conclusion
reveals
critical
gaps
diverse
attitudes
highlighting
need
targeted
educational
interventions.
While
generally
positive,
age
influence
correction,
spectacles
contact
lenses
being
most
preferred
methods.
These
insights
can
guide
healthcare
professionals
developing
tailored
approaches
Tobago.
Children,
Journal Year:
2025,
Volume and Issue:
12(2), P. 191 - 191
Published: Feb. 6, 2025
Background/Objectives:
Asymmetric
myopic
peripheral
defocus
lenses
(MPDLs)
have
proven
to
be
effective
in
slowing
the
progression
of
myopia
Spanish
children
over
a
period
12
months.
The
purpose
this
study
was
assess
MPDL
spectacles’
efficacy
24-month
children.
Methods:
This
extends
follow-up
double-masked,
prospective,
and
randomized
clinical
trial
previously
published
24
Children
from
6
years
were
assigned
two
groups:
control
group
wearing
spherotorical
single
vision
(SVLs)
or
treatment
lenses.
Inclusion
criteria
included
with
less
than
−0.50
D,
astigmatism
below
1.50
best-corrected
visual
acuity
at
least
20/20.
Participants
underwent
cycloplegic
autorefractive
examination
axial
length
(AL)
measurements
baseline
six
twelve
months
already
published,
twenty-four
later
present
study.
Lifestyle
factors,
including
outdoor
activities
digital
device
use,
also
assessed.
Baseline
characteristics,
age,
refractive
error,
AL,
comparable
between
groups.
Dropout
rates
15.9%,
14
participants
lost
follow-up,
distributed
equally
Results:
After
69
remained
study,
comprising
34
SVL
cohort
35
cohort.
Over
months,
showed
significantly
AL
elongation
(0.27
±
0.23
mm
0.37
0.24
mm;
p
=
0.0341).
mean
relative
increase
1.10
0.95%
group,
compared
1.56
1.02%
(p
0.0322).
Younger
exhibited
faster
growth,
while
use
did
not
affect
changes.
Conclusions:
spectacle
substantially
slowed
period,
28.7%
absolute
growth
29.8%
SVL.
These
results
indicate
that
are
an
method
for
progression.
Frontiers in Public Health,
Journal Year:
2025,
Volume and Issue:
13
Published: Feb. 18, 2025
In
China,
approximately
30
and
70%
of
primary
middle
school
students,
respectively,
have
myopia,
making
myopia
prevention
control
necessary.
Eye-use
behaviors
are
closely
related
to
highlighting
the
importance
determining
behavioral
compliance
rates
children.
Parental
awareness
also
affects
children's
behaviors.
Therefore,
we
assessed
myopia-related
parental
school-aged
children
in
different
city
tiers
China
with
refractive
statuses.
A
population-based,
cross-sectional
study
was
conducted
on
Chinese
from
110
cities
aged
7-15
years.
Samples
were
equally
allocated
each
subgroup
tiers,
age
groups,
Questionnaires
designed
investigate
behaviors,
including
responses
sitting
position,
time
eye
use
(single
continuous
near
work
breaks
between,
total
after
day),
rest
(break
style
during
outdoor
per
week),
light
conditions
learning
environment
at
home,
parents'
knowledge
about
control.
Associations
between
analyzed
using
logistic
regression.
total,
896
questionnaires
collected.
The
prevalence
poor
ranged
23.44
84.82%,
highest
lowest
being
position
eye-protecting
lamps,
respectively.
Children
third-tier
more
likely
(p
<
0.01),
a
non-open
view
front
desk
home
=
0.02),
activities
break
times
0.04).
After
adjustment
for
condition
child's
sex,
mainly
associated
not
an
lamp
(odds
ratio
[OR]:
1.95,
95%
confidence
interval
[CI]:
1.40-2.72),
styles
(OR:
1.60,
CI:
1.21-2.12),
excessive
1.45,
1.02-2.05).
Myopia-related
poorly
performed
children,
particularly
among
older
those
living
cities.
Eye-protecting
spent
doing
work,
all
awareness,
suggesting
that
better
helps
long
run.
More
targeted
measures
could
be
adopted
help
improve