Extracellular Vesicles in Kidney Disease DOI Creative Commons
Chunyan Lv

Physiology, Journal Year: 2023, Volume and Issue: unknown

Published: Nov. 10, 2023

The kidney is the mainly apparatus in human body, with a complex organizational structure and diverse pathological changes closely related to other organs. Extracellular vesicles are diameters ranging from tens of nanometers several micrometers, originating multiple intracellular or local cell membranes. They carry various information source cells operate between extrarenal organs, conveying substances cells. play large part signal transmission within Detecting extracellular their cargo can monitor both renal neoplastic nonneoplastic diseases. derived stem cells, loaded bioactive substances, be applied some extent treat Bioengineering drugs using as carriers also playing an increasingly big role treating Research on has achieved certain results preclinical applications, but there still process for large-scale widespread application.

Language: Английский

A novel electrochemical biosensor based on TiO2 nanotube array films for highly sensitive detection of exosomes DOI
Lin He, Guanghai Piao, Yin Xu

et al.

Talanta, Journal Year: 2025, Volume and Issue: 286, P. 127545 - 127545

Published: Jan. 6, 2025

Language: Английский

Citations

0
Advanced extracellular vesicle bioinformatic nanomaterials: from enrichment, decoding to clinical diagnostics DOI Creative Commons

Yawei Zhang,

Liang Zhao, Yaocheng Li

et al.

Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)

Published: Oct. 6, 2023

Abstract Extracellular vesicles (EVs) are membrane nanoarchitectures generated by cells that carry a variety of biomolecules, including DNA, RNA, proteins and metabolites. These characteristics make them attractive as circulating bioinformatic nanocabinets for liquid biopsy. Recent advances on EV biology biogenesis demonstrate EVs serve highly important cellular surrogates involved in wide range diseases, opening up new frontiers modern diagnostics. However, inefficient methods enrichment, well low sensitivity decoding technologies, hinder the use nanocabinet clinical diagnosis. To overcome these challenges, nanotechnology is being actively developed to promote translation This article aims present emerging enrichment strategies platforms analysis, their applications nanomaterials settings.

Language: Английский

Citations

10
Extracellular Vesicles and Immune System Function: Exploring Novel Approaches to Colorectal Cancer Immunotherapy DOI Creative Commons
Antonio Biondi, Marco Vacante, Roberta Catania

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(7), P. 1473 - 1473

Published: July 3, 2024

This review explores the emerging role of extracellular vesicles (EVs) in modulating immune system function and their application novel cancer immunotherapy strategies, with a focus on colorectal (CRC). EVs, as carriers bioactive molecules, have shown potential enhancing responses overcoming limitations traditional therapies. We discuss biogenesis, types, functional roles cell-derived interactions cells, implications antitumor immunity. Challenges such tumor heterogeneity evasion are addressed, alongside promising therapeutic prospects EV-based strategies. comprehensive analysis underscores transformative EVs treatment paradigms.

Language: Английский

Citations

2
Two Decades of Progress in Personalized Medicine of Colorectal Cancer in Serbia—Insights from the Institute for Oncology and Radiology of Serbia DOI Creative Commons
Milena Čavić, Neda Nikolić, Mladen Marinković

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(10), P. 2278 - 2278

Published: Oct. 8, 2024

It is projected that, by 2040, the number of new cases colorectal cancer (CRC) will increase to 3.2 million, and deaths 1.6 highlighting need for prevention strategies, early detection adequate follow-up. In this study, we aimed provide an overview progress in personalized medicine CRC Serbia, with results insights from Institute Oncology Radiology Serbia (IORS), propose guidance tackling observed challenges future.

Language: Английский

Citations

1
Prophylaxis with abemaciclib delays tumorigenesis in dMMR mice by altering immune responses and reducing immunosuppressive extracellular vesicle secretion DOI Creative Commons

Annabell Wolff,

Paula Krone,

Johanna Maennicke

et al.

Translational Oncology, Journal Year: 2024, Volume and Issue: 47, P. 102053 - 102053

Published: July 9, 2024

Language: Английский

Citations

0
Lipid biomarkers in colorectal cancer, with particular emphasis on exosomes – current status and future inferences DOI

Kinga Suska,

Marcin Piotrowski,

Jakub Fichna

et al.

Expert Review of Gastroenterology & Hepatology, Journal Year: 2024, Volume and Issue: 18(8), P. 441 - 456

Published: Aug. 2, 2024

Introduction Colorectal cancer (CRC) is one of the most deadly cancers on a global scale. Diagnosis CRC challenging and it often detected at late stage. Identification relevant biomarkers could lead to development effective diagnostic methods for CRC.

Language: Английский

Citations

0
Prospects and challenges of targeted extracellular vesicles drug delivery for cancer treatment DOI Creative Commons

Fatemeh Maher,

Ali Samadi, Peyman Asadi

et al.

Extracellular Vesicle, Journal Year: 2024, Volume and Issue: 4, P. 100059 - 100059

Published: Dec. 1, 2024

Language: Английский

Citations

0
Extracellular Vesicles in Kidney Disease DOI Creative Commons
Chunyan Lv

Physiology, Journal Year: 2023, Volume and Issue: unknown

Published: Nov. 10, 2023

The kidney is the mainly apparatus in human body, with a complex organizational structure and diverse pathological changes closely related to other organs. Extracellular vesicles are diameters ranging from tens of nanometers several micrometers, originating multiple intracellular or local cell membranes. They carry various information source cells operate between extrarenal organs, conveying substances cells. play large part signal transmission within Detecting extracellular their cargo can monitor both renal neoplastic nonneoplastic diseases. derived stem cells, loaded bioactive substances, be applied some extent treat Bioengineering drugs using as carriers also playing an increasingly big role treating Research on has achieved certain results preclinical applications, but there still process for large-scale widespread application.

Language: Английский

Citations

0