Optimization of screening-level risk assessment and priority selection of emerging pollutants – The case of pharmaceuticals in European surface waters

Environment International, Journal Year: 2019, Volume and Issue: 128, P. 1 - 10

Published: April 24, 2019

Pharmaceuticals in surface waters have raised significant concern recent years for their potential environmental effects. This study identified that at present a total of 477 substances (including 66 metabolites and transformation products) been analyzed European waters. Around 60% (284) these compounds belonging to 16 different therapeutic groups were positively detected one or more 33 countries. To conveniently effectively prioritize high-risk compounds, an optimized method considers the frequency concentrations above predicted no effects levels was developed on basis traditional method, it then used identify screen candidate priority pollutants The results proved feasibility advantages method. classified into 5 categories (high, moderate, endurable, negligible safe) depending distribution pharmaceuticals. Circa 9% (45 out 477) showed risk aquatic ecosystems. Among 45 12 indicated high environments, while 17 7 moderate small-scale risks, respectively.

Language: Английский

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Future water quality monitoring: improving the balance between exposure and toxicity assessments of real-world pollutant mixtures

Environmental Sciences Europe, Journal Year: 2019, Volume and Issue: 31(1)

Published: Feb. 19, 2019

Environmental water quality monitoring aims to provide the data required for safeguarding environment against adverse biological effects from multiple chemical contamination arising anthropogenic diffuse emissions and point sources. Here, we integrate experience of international EU-funded project SOLUTIONS shift focus a few legacy chemicals complex mixtures, identify relevant drivers toxic effects. Monitoring serves range purposes, control ecological status compliance specific uses, such as drinking abstraction. Various sampling techniques, target, suspect non-target analyses well an array in vitro, vivo situ bioanalytical methods were advanced improve contamination. Major improvements broader applicability include tailored screening identification techniques more diverse set chemicals, higher detection sensitivity, standardized protocols chemical, toxicological, assessments combined with systematic evidence evaluation techniques. No single method or combination is able meet all divergent purposes. Current approaches tend emphasize either targeted exposure effect detection. argue that, irrespective purpose, assessment results would benefit substantially obtaining linking information on occurrence both potentially In this paper, specify to: (1) contaminants, (2) assess impact aquatic ecosystems, (3) quantify cause–effect relationships between contaminants Specific strategies link are outlined each these distinct goals. These have been developed explored using case studies Danube Rhine river basins rivers Iberian Peninsula. suffers biases resulting differences associated uncertainty analyses. While ignore gaps (i.e., missing contaminants), effect-based penalize increased factors. This integrated work suggests ways deal mixture exposures balanced way, thus provides guidance future environmental monitoring.

Language: Английский

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A critical review of synthetic chemicals in surface waters of the US, the EU and China

Environment International, Journal Year: 2019, Volume and Issue: 131, P. 104994 - 104994

Published: July 11, 2019

There is a wide concern that emerging organic pollutants (EOPs) in surface water could adversely affect human health and wildlife. However, the geographic distribution, exposure pattern ecological risk of are poorly understood at global scale. This paper provides comprehensive survey on level EOPs China, US EU based published literature. The hazard three categories EOPs, namely pharmaceuticals personal care products (PPCPs), pesticides industrial chemicals was further evaluated by adopting novel Aquatic HazPi index jointly accounts for persistence, bioaccumulation, toxicity bioactivity. Furthermore, correlation analysis land use with status regarding synthetic conducted. According to data reported between 2010 2016, concentration higher than China. PPCPs generally lower both while China US. Among whose median >10 ng/L, antiretroviral Efavirenz, pesticide Fipronil, octocrylene, an chemical cosmetic ingredient, were found highest aquatic value. Lastly, spatial distribution hazardous shown depend local landscape usages. Our study first broad overview major economic entities: EU.

Language: Английский

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(Eco)toxicological tests for assessing impacts of chemical stress to aquatic ecosystems: Facts, challenges, and future

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 795, P. 148776 - 148776

Published: July 1, 2021

Monitoring of chemicals in the aquatic environment by chemical analysis alone cannot completely assess and predict effects on species ecosystems. This is primarily because increasing number (unknown) stressors mixture present environment. In addition, ability ecological indices to identify underlying causing negative limited. Therefore, additional complementary methods are needed that can address biological a direct manner provide link exposure, i.e. (eco)toxicological tests. (Eco)toxicological tests defined as test systems expose components (cells, individuals, populations, communities) (environmental mixtures of) register effects. These measure responses at sub-organismal (biomarkers vitro bioassays), whole-organismal, population, or community level. We performed literature search obtain state-of-the-art overview ecotoxicological available for assessing impacts biota reveal datagaps. total, we included 509 biomarkers, 207 bioassays, 422 measuring whole-organismal level, 78 population- community- ecosystem-level. Tests level biomarkers were most abundant invertebrates fish, whilst bioassays mostly based mammalian cell lines. ecosystem-level almost missing organisms other than microorganisms algae. an various extrapolation challenges faced using data from these suggest some forward looking perspectives. Although extrapolating measured relevant protection goals remains challenging, combination experiments models key more comprehensive assessment

Language: Английский

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High-resolution mass spectrometry to complement monitoring and track emerging chemicals and pollution trends in European water resources

Environmental Sciences Europe, Journal Year: 2019, Volume and Issue: 31(1)

Published: Sept. 30, 2019

Abstract Currently, chemical monitoring based on priority substances fails to consider the majority of known environmental micropollutants not mention unexpected and unknown chemicals that may contribute toxic risk complex mixtures present in environment. Complementing component- effect-based with wide-scope target, suspect, non-target screening (NTS) high-resolution mass spectrometry (HRMS) data is recommended support impact assessment. This will allow for detection newly emerging compounds transformation products, retrospective efforts, identification possible drivers toxicity by correlation effects or modelling expected future abatement scenarios. HRMS becoming increasingly available many laboratories. Thus, time right establish harmonize methods, train staff, record samples from regular events surveys. strongly enhance value evaluating pollution problems, at limited additional costs. Collaboration exchange a European-to-global scale essential maximize benefit screening. Freely accessible platforms, inter-laboratory trials, involvement international partners networks are recommended.

Language: Английский

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Unraveling longitudinal pollution patterns of organic micropollutants in a river by non-target screening and cluster analysis

The Science of The Total Environment, Journal Year: 2020, Volume and Issue: 727, P. 138388 - 138388

Published: April 6, 2020

Language: Английский

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Linking pollution and cancer in aquatic environments: A review

Environment International, Journal Year: 2021, Volume and Issue: 149, P. 106391 - 106391

Published: Jan. 27, 2021

Due to the interconnectedness of aquatic ecosystems through highly effective marine and atmospheric transport routes, all are potentially vulnerable pollution. Whilst links between pollution increased mortality wild animals have now been firmly established, next steps should be focus on specific physiological pathways pathologies that link wildlife health deterioration. One pollution-induced at centre attention in ecological evolutionary research is cancer, as anthropogenic contamination has resulted a rapid increase oncogenic substances natural habitats. cancer an emerging topic, systematic reviews many case studies published over recent decades scarce. This direction would (1) provide better understanding mechanisms connecting processes non-model organisms (reducing current bias towards human lab-animal research), (2) allow us predict vulnerability different populations contamination. article combines information available within scientific literature about occurrences semi-aquatic species. For first aim, we use knowledge from species suggest including main metabolic detoxification pathways, oxidative damage effects, infections, changes microbiome. second determine which types more mainly associated with ecosystems, causes. We also discuss role migration exposing pollutants. Finally, novel avenues, experimental approaches, analysis effects pollutant cocktails long-term chronic exposure lower levels pollutants, already databases gene expression differently polluted

Language: Английский

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A review of modeling pesticides in freshwaters: Current status, progress achieved and desirable improvements.

Environmental Pollution, Journal Year: 2022, Volume and Issue: 316, P. 120553 - 120553

Published: Nov. 5, 2022

This study comprises a critical review of modeling pesticides in surface waters. The aim was to update the status use models simulate fate from diffuse sources. ISI papers were selected on Scopus and information concerning areas, type (herbicides, fungicides insecticides), model, methodology adopted (i.e., calibration and/or validation, spatial temporal scales) analyzed. studies carried out Europe (55.5%), North America (22.3%), Asia (13.9%) South (8.3%). Soil Water Assessment Tool proved be most used model (45.95%). Herbicides modeled (71.4%), followed by insecticides (18.2%) (10.4%). main herbicides atrazine, metolachlor, isoproturon, glyphosate, acetochlor. Insecticides such as chlorpyrifos metaldehyde. Chlorothalonil, tebuconazole) widely investigated. Based published studies, it found that approaches for assessing are constantly evolving algorithms work well with diverse watershed conditions, management strategies, pesticide properties. Several reported concentrations exceeding ecotoxicological thresholds revealing water contamination agriculture urban areas is priority issue current global concern.

Language: Английский

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Review: mountain lakes as freshwater resources at risk from chemical pollution

Environmental Sciences Europe, Journal Year: 2023, Volume and Issue: 35(1)

Published: Jan. 13, 2023

Abstract Background Chemical pollution forms a severe threat for human and environmental health. While the risks European lowland water bodies are well known, there is little knowledge on remote aquatic ecosystems particularly mountain lakes, despite their importance provision of freshwater. Here, we critically review current exposure risk by chemical lakes present tiered approach how to advance effectively our understanding in future. Results Generally, pollutant monitoring data currently incomplete, with many regions substances having been only poorly investigated. More reliable exist persistent organic pollutants (POPs). However, increasing evidence that even exposed wide range pollutants. Among them potent pesticides used agricultural biocidal applications, such as diazinon permethrin. The follows complex pattern. Pollutants introduced into via atmospheric deposition run-off from watershed, but also local sources, like tourism pastoralism. Our assessment recent biomonitoring studies suggest widespread chronic toxic crustacean ranges. If ranges pastoralism, acute effects possible. Thereby, vulnerability has be expected high due harsh conditions at altitudes, organism’s traits, insular position lower species richness altitudes. Furthermore, biological processes leading degradation under ecological ecosystems. Conclusion sensitivity investigated, existing it very likely do suffer pollution-induced toxicity. To verify this suggestion expand knowledge, necessary future combine more holistic modelling links effects. Only then will possible obtain impact protect these fragile

Language: Английский

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Novel Groundwater Quality Index (GWQI) model: A Reliable Approach for the Assessment of Groundwater

Results in Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 104265 - 104265

Published: Feb. 1, 2025

Language: Английский

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