A Case-Control Study on Risk Factors and Their Interactions with Prediabetes among the Elderly in Rural Communities of Yiyang City, Hunan Province DOI Creative Commons
Zhao Hu, Fan Gao, Lulu Qin

et al.

Journal of Diabetes Research, Journal Year: 2019, Volume and Issue: 2019, P. 1 - 8

Published: Feb. 18, 2019

Background . The prevalence of prediabetes has been increasing significantly in recent years. Individuals with have an increased risk developing diabetes and cardiovascular diseases. objectives this study were to identify factors for their interactions among the elderly rural communities Hunan Province provide a scientific basis prevention. Methods A case-control was conducted explore areas. general sociodemographic information, lifestyle behaviours, physiological results individuals controls collected by questionnaire laboratory testing. Conditional logistic regression performed elderly, additive used analyse between factors. Results total 425 subjects included case group, normal plasma glucose levels control group. main family history (OR=2.48; 95% CI: 1.13, 5.46), physical inactivity id="M2">OR=3.27; 1.95, 5.49), lack health literacy on prevention id="M3">OR=3.26; 1.62, 6.55), hypertension id="M4">OR=2.01; 1.38, 2.93), overweight id="M5">OR=2.53; 1.67, 3.81), obesity id="M6">OR=3.08; 1.48, 6.40), high waist-to-hip ratio (WHR) id="M7">OR=2.26; 1.45, 3.51). Additive detected WHR inactivity, relative excess due interaction (RERI) 6.30 (95% 0.42, 12.18), or obesity, RERI 2.92 0.56, 5.29). Conclusion independent are diabetes, control, hypertension, WHR. prediabetes. These findings significant implications

Language: Английский

Prevalence of Prediabetes, Diabetes, and Its Associated Risk Factors among Males in Saudi Arabia: A Population-Based Survey DOI Creative Commons
Khaled K. Aldossari,

Abdulrahman Aldiab,

Jamaan Al‐Zahrani

et al.

Journal of Diabetes Research, Journal Year: 2018, Volume and Issue: 2018, P. 1 - 12

Published: Jan. 1, 2018

Objectives . The study aims at determining the prevalence of prediabetes and diabetes ascertaining some concomitant risk factors among males in Saudi Arabia. Methods A population-based cross-sectional including 381 adult from different institutions was recruited. Odds ratios for were calculated using log-binomial multinomial logistic regression, STATA version 12. Results participants included diabetic with a median age 45 years, average body mass index 25 ± 40 kg/m 2 , whereas waist circumferences ranged 66 to 180 cm male population. In addition, 27.82% had normal BMI, 32.28% overweight, 36.22% obese. Around 36% higher circumference, that is, >102 cm. Age, marital status, educational attainment statistically significant predictors diabetes. Conclusion This found 9.2% 27.6%, respectively, Al-Kharj increase include older age, obesity being married, smoker, having civilian job less education. All these except smoking status type. order evaluate causal relationship factors, prospective studies are required future.

Language: Английский

Citations

84

Prevalence and Predictors of Pre-Diabetes and Diabetes among Adults 18 Years or Older in Florida: A Multinomial Logistic Modeling Approach DOI Creative Commons

Ifechukwude O. Okwechime,

Shamarial Roberson,

Agricola Odoi

et al.

PLoS ONE, Journal Year: 2015, Volume and Issue: 10(12), P. e0145781 - e0145781

Published: Dec. 29, 2015

Individuals with pre-diabetes and diabetes have increased risks of developing macro-vascular complications including heart disease stroke; which are the leading causes death globally. The objective this study was to estimate prevalence diabetes, investigate their predictors among adults ≥18 years in Florida.Data covering time period January-December 2013, were obtained from Florida's Behavioral Risk Factor Surveillance System (BRFSS). Survey design declared using SVYSET statement STATA 13.1. Descriptive analyses performed diabetes. Predictors investigated multinomial logistic regression model. Model goodness-of-fit evaluated both test proposed by Fagerland, Hosmer, Bofin, as well as, Hosmer-Lemeshow's goodness fit test.There approximately 2,983 (7.3%) 5,189 (12.1%) Florida diagnosed respectively. Over half respondents white, married over age 45 while 36.4% reported being physically inactive, overweight (36.4%) or obese (26.4%), hypertensive (34.6%), hypercholesteremic (40.3%), 26% arthritic. Based on final multivariable model, only (Relative Ratio [RRR] = 1.85, 95% Confidence Interval [95% CI] 1.41, 2.42), (RRR 3.41, CI 2.61, 4.45), 1.69, 1.33, 2.15), hypercholesterolemic 1.94, 1.55, 2.43), arthritic 1.24, 1.00, 1.55) had significant associations pre-diabetes. However, more strengths tended be higher than for association For instance, relative risk ratios between 2.00, 2.57), 4.04, 3.22, 5.07), 2.66, 2.08, 3.41), 1.98, 1.61, 2.45) 1.28, 1.04, 1.58) all further away null Moreover, a number variables such age, income level, sex, level physical activity but not increasing lower income, males, inactivity. Insufficient no pre-diabetes.There is evidence differences strength across levels status (pre-diabetes diabetes) Florida. It important monitor populations at high so help guide health programming decisions resource allocations control condition.

Language: Английский

Citations

52

Circulating miRNAs as a Predictive Biomarker of the Progression from Prediabetes to Diabetes: Outcomes of a 5-Year Prospective Observational Study DOI Open Access
Iwona Sidorkiewicz, Magdalena Niemira, Katarzyna Maliszewska

et al.

Journal of Clinical Medicine, Journal Year: 2020, Volume and Issue: 9(7), P. 2184 - 2184

Published: July 10, 2020

Due to a global increase in the prevalence of type 2 diabetes mellitus (T2DM), there is an urgent need for early identification prediabetes, as these people have highest risk developing diabetes. Circulating miRNAs shown potential progression biomarkers other diseases. This study aimed conduct baseline comparison serum-circulating prediabetic individuals, with distinction between those who later progressed T2DM and did not. The expression levels 798 using NanoString technology were examined. Spearman correlation, receiver operating characteristic (ROC) curve analysis, logistic regression modeling performed. Gene ontology (GO) canonical pathway analysis used explore biological functions miRNA target genes. revealed that three upregulated serum samples patients T2DM. Pathway showed genes mainly significantly enriched neuronal NO synthase (nNOS) signaling neurons, amyloid processing, hepatic cholestasis. ROC demonstrated miR-491-5p, miR-1307-3p, miR-298 can be introduced diagnostic tool prediction (area under (AUC) = 94.0%, 88.0%, 84.0%, respectively). Validation by real-time quantitative polymerase chain reaction (qRT-PCR) confirmed our findings. results suggest circulating potentially predictive patients.

Language: Английский

Citations

40

Association of General and Abdominal Obesity With Hypertension, Dyslipidemia and Prediabetes in the PREDAPS Study DOI

F. Javier Sangrós,

Jesús Torrecilla,

Carolina Giráldez‐García

et al.

Revista Española de Cardiología (English Edition), Journal Year: 2017, Volume and Issue: 71(3), P. 170 - 177

Published: Aug. 5, 2017

Language: Английский

Citations

48

miR-10b and miR-223-3p in serum microvesicles signal progression from prediabetes to type 2 diabetes DOI
Marcelina Párrizas, Xavier Mundet, Carlos Castaño

et al.

Journal of Endocrinological Investigation, Journal Year: 2019, Volume and Issue: 43(4), P. 451 - 459

Published: Nov. 12, 2019

Language: Английский

Citations

40

Sex and age differences in prevalence and risk factors for prediabetes in Mexican-Americans DOI
Kristina Vatcheva, Susan P. Fisher‐Hoch, Belinda M. Reininger

et al.

Diabetes Research and Clinical Practice, Journal Year: 2019, Volume and Issue: 159, P. 107950 - 107950

Published: Dec. 2, 2019

Language: Английский

Citations

39

Modifiable Risk Factors for Periodontitis and Diabetes DOI
Wenche S. Borgnakke

Current Oral Health Reports, Journal Year: 2016, Volume and Issue: 3(3), P. 254 - 269

Published: June 24, 2016

Language: Английский

Citations

39

Health risks and interventions in prediabetes: A review DOI
Roshan Kumar Mahat,

Neelima Singh,

Manisha Arora

et al.

Diabetes & Metabolic Syndrome Clinical Research & Reviews, Journal Year: 2019, Volume and Issue: 13(4), P. 2803 - 2811

Published: July 1, 2019

Language: Английский

Citations

38

Asociación de obesidad general y abdominal con hipertensión, dislipemia y presencia de prediabetes en el estudio PREDAPS DOI

F. Javier Sangrós,

Jesús Torrecilla,

Carolina Giráldez‐García

et al.

Revista Española de Cardiología, Journal Year: 2017, Volume and Issue: 71(3), P. 170 - 177

Published: June 2, 2017

Citations

39

“Non-modifiable” Risk Factors for Periodontitis and Diabetes DOI
Wenche S. Borgnakke

Current Oral Health Reports, Journal Year: 2016, Volume and Issue: 3(3), P. 270 - 281

Published: June 23, 2016

Language: Английский

Citations

35