Dietary amino acid intake and sleep duration are additively involved in future cognitive decline in Japanese adults aged 60 years or over: a community-based longitudinal study

BMC Geriatrics, Journal Year: 2023, Volume and Issue: 23(1)

Published: Oct. 11, 2023

Sleep duration and amino acid intake are independently associated with cognitive decline. This study aimed to determine the longitudinal association between sleep impairment incidence examine involvement of diet, particularly intake, in these associations community dwellers.In this a community-based setting, we analyzed data from 623 adults aged 60-83 years without at baseline. was assessed using self-report questionnaire. Amino 3-day dietary records. Cognitive defined as Mini-Mental State Examination score ≤ 27. Participants were classified into short-, moderate-, long-sleep groups according baseline (≤ 6, 7-8, > 8 h, respectively). Using moderate reference, odds ratios (ORs) 95% confidence intervals (CIs) short- for cognitive-impairment estimated generalized estimating equation. sex-stratified quartiles (Q) 19 intake: Q1 Q2-Q4 low- middle high-intake groups, respectively. middle- ORs CIs low equation each sleep-duration group. Follow-up period, sex, age, body mass index, depressive symptoms, education, smoking status, employment aids use, physical activity, medical history, covariates.Mean follow-up period 6.9 ± 2.1 years. Adjusted (95% CIs) 0.81 (0.49-1.35, P = 0.423) 1.41 (1.05-1.87, 0.020), Particularly long sleepers (i.e., h), significantly cystine, proline, serine [adjusted 2.17 (1.15-4.11, 0.017), 1.86 (1.07-3.23, 0.027), 2.21 (1.14-4.29, 0.019), respectively].Community-dwelling ≥ 60 who longer more likely have decline, attention should be paid intake.

Language: Английский

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Association of Sleep Status With Cognitive Functions in Centenarians: Evidence From Hainan Centenarian Cohort

The Journals of Gerontology Series B, Journal Year: 2023, Volume and Issue: 79(3)

Published: Dec. 27, 2023

Abstract Objectives This study aimed to analyze the association between sleep quality, duration, and cognitive functions among centenarians. Methods The baseline data of China Hainan Centenarians Cohort Study served as foundation for this study. Logistic regression was utilized demonstrate relationship status impairment. Moreover, a canonical correlation analysis performed these variables. Results A total 994 centenarians were included. After adjustment, poor quality had an odds ratio 1.77 (95% confidence interval [CI]: 1.00–3.09) impairment when compared with normal quality. who slept more than 9 hr stronger severe impairment, indicated by 1.41 CI: 1.02–1.96), those 7–9 hr. Additionally, results revealed that linear combination V1, primarily determined latency, daytime dysfunction, subjective associated function; function W1, mainly orientation, attention calculation, memory. Discussion There exists in centenarians, well duration >9 at night primary domains are It is imperative monitor safeguard linked older individuals,

Language: Английский

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Correlates of Subjective Cognitive Decline in Black American Men

The Journal of Prevention of Alzheimer s Disease, Journal Year: 2024, Volume and Issue: 11(6), P. 1734 - 1740

Published: Aug. 29, 2024

Past research suggests that subjective cognitive decline serves as an early and potentially important indicator individuals may be at risk for future or neurodegenerative conditions. However, there is a dearth of studies on factors influencing the experience in Black Americans, especially American men.

Language: Английский

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Correlation between the APOE ε4 genotype, lifestyle habits, and cognitive deficits in Chinese adults over 60: a cross-sectional analysis in China

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Nov. 21, 2024

is regarded as the most significant genetic contributor linked to mild cognitive impairment (MCI) and Alzheimer's disease (AD). Daily life elements might also influence abilities some extent. This research aimed investigate whether carrying

Language: Английский

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Factors Associated With Sleep Quality in Hospitalized Persons With Dementia

Alzheimer Disease & Associated Disorders, Journal Year: 2022, Volume and Issue: 36(3), P. 253 - 258

Published: March 25, 2022

Background: Factors associated with sleep quality have not been well examined in hospitalized older persons dementia, who are at high risk for impaired sleep. The aim was to identify factors among dementia. Methods: This secondary analysis used baseline data from a cluster randomized trial. included delirium severity, pain, depression, behavioral and psychological symptoms of dementia (BPSD), daytime physical activity. Multiple stepwise linear regressions evaluated related dimensions (sleep duration, efficiency, latency, fragmentation; measured by the MotionWatch 8). Results: Increased activity higher duration [β=0.164; 95% confidence interval (CI), 0.111-0.717; P =0.008; 7.7% variance] efficiency (β=0.158; CI, 0.020-0.147; =0.010; 5.4% variance), less fragmentation (β=−0.223; −0.251 −0.077; <0.001; 10.4% variance). Higher BPSD significantly prolonged latency (β=0.130; 0.098-2.748; =0.035; 3.7% Conclusion: Results suggest need encourage reduce or manage improve

Language: Английский

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Association between personality characteristics and sleep quality among Chinese middle-aged and older adults: evidence from China family panel studies

BMC Public Health, Journal Year: 2023, Volume and Issue: 23(1)

Published: Dec. 5, 2023

Abstract Background Poor sleep quality will have adverse effects on physical and mental health, of life other aspects middle-aged older adults. Sleep is affected by many factors. Whether the measures participants had changed in previous or subsequent time period not easily taken into account. Moreover, there been no studies this topic Chinese The objective study was to mitigate bias assessment, analyze association between personality traits Methods data came from China Family Panel Studies (CFPS). A total 6031 aged ≥ 45 years were included study. Personality characteristics evaluated based scores each dimension Big Five traits. duration perception used as indicators measure quality. Logistic models relationship perception, respectively. Results 4.5% abnormal duration, 14.4% a pessimistic perception. Conscientiousness rated highest among (3.97 ± 0.6). Participants with higher for extraversion more normal (OR = 0.77, 95% CI: 0.64–0.93) optimistic 0.86, 0.76–0.96). Using Internet feeling unwell past week moderating effect impact conscientiousness respectively (but overall quality). In addition, spouse recent discomfort tended Conclusions score traits, better Having important factors affecting their Specific intervention should be carried out adults poor make are closer extraversion. without spouses encouraged marry remarry. We strengthen health management medical expenditures

Language: Английский

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The impact of sleep quality and its change on the long-term risk of stroke in middle-aged and elderly people: Findings from the English Longitudinal Study of Ageing

Sleep Medicine, Journal Year: 2023, Volume and Issue: 107, P. 281 - 288

Published: May 20, 2023

Language: Английский

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Self-Reported Sleep Characteristics Associated with Cardiovascular Disease Among Older Adults Living in Rural Eastern China: A Population-Based Study

Clinical Interventions in Aging, Journal Year: 2022, Volume and Issue: Volume 17, P. 811 - 824

Published: May 1, 2022

Purpose: To investigate the cross-sectional associations of self-reported sleep characteristics with cardiovascular diseases (CVDs) and multimorbidity in older adults living rural Eastern China. Patients Methods: This population-based study included 4618 participants (age ≥ 65 years; 56.5% women) In March–September 2018, data were collected through interviews, clinical examinations, neuropsychological testing, laboratory tests. Sleep parameters assessed using Pittsburgh Quality Index, Epworth Sleepiness Score, Berlin questionnaire. Coronary heart disease (CHD), failure (HF), stroke defined according to in-person neurological electrocardiogram examination. Data analyzed logistic regression restricted cubic spline regression. Results: CHD was diagnosed 991 participants, HF 135 696 participants. The multivariable-adjusted odds ratio (OR) 1.27 (95% CI, 1.09– 1.49) for duration ≤ 6 hours/night (vs > 6– 8 hours/night), 1.40 (1.20– 1.62) poor quality, 1.22 (1.04– 1.43) high risk obstructive apnea (OSA). OR 2.16 (1.38– 3.39) hours/night, 1.76 (1.22– 2.54) OSA. addition, 1.23 1.46) 1.32 (1.01– 1.72) excessive daytime sleepiness, 1.42 (1.19– 1.70) (≥ 2 CVDs) stronger than that problems a single CVD. Conclusion: Extreme duration, OSA, other associated CVDs, especially multimorbidity. Keywords: sleep, coronary disease, failure, stroke,

Language: Английский

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Development and validation of a diagnostic model for cerebral small vessel disease among rural older adults in China

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: July 5, 2024

Objectives Cerebral small vessel disease (CSVD) visible on MRI can be asymptomatic. We sought to develop and validate a model for detecting CSVD in rural older adults. Methods This study included 1,192 participants the sub-study within Multidomain Interventions Delay Dementia Disability Rural China. Total sample was randomly divided into training set validation set. markers of were assessed following international criteria, total burden scale from 0 4. Logistic regression analyses used screen risk factors diagnostic model. A nomogram visualize Model performance using area under receiver-operating characteristic curve (AUC), calibration plot, decision analysis. Results The age, high blood pressure, white cell count, neutrophil-to-lymphocyte ratio (NLR), history cerebral infarction. AUC 0.71 (95% CI, 0.67–0.76) 0.69 0.63–0.76) showed coherence between predicted observed probabilities both sets. had higher net benefits than strategy assuming all either at or low probability thresholds ranging 50–90% set, 65–98% Conclusion that integrates routine clinical could detect adults, with good discrimination calibration. has implication decision-making.

Language: Английский

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Associations of 24-hour movement behaviors with depressive symptoms in rural-dwelling older adults: a compositional data analysis

Aging Clinical and Experimental Research, Journal Year: 2024, Volume and Issue: 36(1)

Published: Aug. 9, 2024

Abstract Background We aimed to explore the association of sleep duration with depressive symptoms among rural-dwelling older adults in China, and estimate impact substituting sedentary behavior (SB) physical activity (PA) on symptoms. Methods This population-based cross-sectional study included 2001 (age ≥ 60 years, 59.2% female). Sleep was assessed using Pittsburgh Quality Index. used accelerometers assess SB PA, 15-item Geriatric Depression Scale Data were analyzed restricted cubic splines, compositional logistic regression, isotemporal substitution models. Results Restricted spline curves showed a U-shaped between daily likelihood ( P -nonlinear < 0.001). Among 7 h/day, reallocating min/day spent PA associated multivariable-adjusted odds ratio (OR) 0.81 (95% confidence interval [CI] = 0.78–0.84) 0.79 (0.76–0.82), respectively, for OR 0.78 (0.74–0.84), 0.73 (0.69–0.78), 0.94 (0.92–0.96), Conclusions Our reveals rural further shows that replacing or vice versa is reduced likelihoods depending duration.

Language: Английский

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