Interplay between Comorbidities and Long COVID: Challenges and Multidisciplinary Approaches
Biomolecules,
Journal Year:
2024,
Volume and Issue:
14(7), P. 835 - 835
Published: July 11, 2024
Long
COVID,
a
name
often
given
to
the
persistent
symptoms
following
acute
SARS-CoV-2
infection,
poses
multifaceted
challenge
for
health.
This
review
explores
intrinsic
relationship
between
comorbidities
and
autoimmune
responses
in
shaping
trajectory
of
long
COVID.
Autoantibodies
have
emerged
as
significant
players
COVID-19
pathophysiology,
with
implications
disease
severity
progression.
Studies
show
immune
dysregulation
persisting
months
after
marked
by
activated
innate
cells
high
cytokine
levels.
The
presence
autoantibodies
against
various
autoantigens
suggests
their
potential
comorbid
factors
Additionally,
formation
complexes
may
lead
severe
progression,
highlighting
urgency
early
detection
intervention.
Furthermore,
COVID
is
highly
linked
cardiovascular
complications
neurological
symptoms,
posing
challenges
diagnosis
management.
Multidisciplinary
approaches,
including
vaccination,
tailored
rehabilitation,
pharmacological
interventions,
are
used
mitigating
COVID’s
burden.
However,
numerous
persist,
from
evolving
diagnostic
criteria
addressing
psychosocial
impact
predicting
outcomes.
Leveraging
AI-based
applications
holds
promise
enhancing
patient
management
improving
our
understanding
As
research
continues
unfold,
unravelling
complexities
remains
paramount
effective
intervention
care.
Language: Английский
Are the Comorbidities Constitute an Intrinsic Factor for Long COVID?
Published: May 2, 2024
Long
COVID,
a
name
often
given
to
the
persistent
symptoms
following
acute
SARS-CoV-2
infection,
poses
multifaceted
challenge
for
health.
This
review
explores
intrinsic
relationship
between
comorbidities
and
autoimmune
responses
in
shaping
trajectory
of
long
COVID.
Autoantibodies
have
emerged
as
significant
players
COVID-19
pathophysiology,
with
implications
disease
severity
progression.
Studies
show
immune
dysregulation
persisting
months
after
marked
by
activated
innate
cells
high
cytokine
levels.
The
presence
autoantibodies
against
various
autoantigens
suggests
their
potential
comorbid
factors
Additionally,
formation
complexes
may
lead
severe
progression,
highlighting
urgency
early
detection
intervention.
Furthermore,
COVID
is
highly
linked
cardiovascular
complications
neurological
symptoms,
posing
challenges
diagnosis
management.
Multidisciplinary
approaches,
including
vaccination,
tailored
rehabilitation,
pharmacological
interventions,
are
used
mitigating
COVID's
burden.
However,
numerous
persist,
from
evolving
diagnostic
criteria
addressing
psychosocial
impact
predicting
outcomes.
Leveraging
AI-based
applications
holds
promise
enhancing
patient
management
improving
our
understanding
As
research
continues
unfold,
unravelling
complexities
remains
paramount
effective
intervention
care.
Language: Английский
Associations between COVID-19 infection experiences and mental health problems among Chinese adults: A large cross-section study
Journal of Affective Disorders,
Journal Year:
2023,
Volume and Issue:
340, P. 719 - 727
Published: Aug. 18, 2023
Language: Английский
Difference in the risk of discrimination on psychological distress experienced by early wave infected and late wave infected COVID-19 survivors in Japan
Scientific Reports,
Journal Year:
2023,
Volume and Issue:
13(1)
Published: Aug. 12, 2023
The
psychological
distress
experienced
by
coronavirus
disease
of
2019
(COVID-19)
survivors
after
recovery
from
the
illness
is
amplified
discrimination
endured
because
their
infection
status.
However,
difference
in
risk
facing
and
experiencing
early
late
waves
COVID-19
pandemic
remain
unclear.
This
study
aimed
to
investigate
whether
status
was
lower
or
on
more
serious
later,
rather
than
earlier
waves.
We
conducted
two
online
surveys
collect
data
divided
into
groups.
participants
with
scores
five
Kessler
Psychological
Distress
Scale
were
identified
as
having
distress.
based
if
they
had
being
blamed,
some
type
discrimination,
themselves
families
maligned.
timing
split
infected
during
for
2021
later
2022
participants.
Modified
Poisson
regression
analyses
performed
using
experiences
criteria
predictors.
further
presence
a
criteria,
addition
interaction
effect
these
es.
6010
who
5344
analyzed.
risks
forms
maligned
significantly
group
those
Experiences
highly
associated
waves,
while
only
blamed
showed
significant
association.
Risk
found
be
whereas
shown
Therefore,
we
submit
that
it
important
support
face
attempt
decrease
current
discriminatory
climate
caused
pandemic.
Language: Английский
Psychological distress after COVID-19 recovery and subsequent prolonged post-acute sequelae of COVID-19: A longitudinal study with 1-year follow-up in Japan
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 24, 2024
Abstract
Background
This
study
investigated
the
longitudinal
association
between
psychological
distress
in
post-acute
phase
and
subsequent
prolonged
sequelae
of
COVID-19
(PASC)
among
individuals
with
PASC.
Methods
An
online
survey
1-year
interval
was
conducted
from
July
to
September
2021
(T1)
2022
(T2).
Individuals
who
were
20-years-old
or
older,
had
a
positive
Polymerase
Chain
Reaction
test,
one
month
post-infection,
did
not
select
“Nothing”
question
regarding
PASC
presence
included.
The
primary
outcome
at
T2.
general,
respiratory,
muscular,
neurological,
gastrointestinal,
dermatological,
cardiac
symptoms
T2
also
used
as
an
patients
relevant
time
1
(T1).
Exposure
measured
using
Kessler
scale
(K6)
T1,
those
whose
K6
13
higher
identified
having
distress.
Marginal
structure
models
robust
standard
errors
examine
T1
any
T2,
associations
each
symptom
participants
T1.
Results
A
total
1674
analyzed;
17%had
;
In
total,
818
(48.9%),
523
(31.2%),
672
(40.1%)
reported
neurological
respectively.
odds
(Odds
Ratio
[OR]
=1.81,
95%
Confidence
Interval
[CI]=
1.08
–
3.03)
general
respiratory
(OR
=
1.95,
CI
1.02
3.76;
OR
2.44,
1.03
5.80).
Conclusion
Psychological
may
lead
symptoms,
mainly
follow-up
Key
Messages
before
infection
during
acute
predicts
Post-Acute
Sequelae
(PASC);
however,
PASC,
it
is
unclear
whether
indicated
that
led
levels
especially
follow-up.
Therefore,
mental
health
care
for
help
improve
mitigate
Language: Английский
Physical exercise/sports ameliorate the internet addiction from college students during the pandemic of COVID-19 in China
Frontiers in Public Health,
Journal Year:
2023,
Volume and Issue:
11
Published: Dec. 21, 2023
The
rapid
advancement
of
modern
technology
has
significantly
driven
progress
in
various
IT-related
activities,
resulting
a
substantial
increase
internet
penetration
rates,
particularly
among
college
students.
utilization
the
become
one
most
essential
tools
our
society.
However,
addiction
(IA)
emerged
as
serious
concern,
students,
adversely
affecting
academic
performance
and
having
significant
psychological
psychiatric
implications.
aim
current
study
was
to
determine
impact
physical
exercise,
gender
year
on
IA
In
present
study,
we
investigated
usage,
engagement
sports
students
from
Western,
Middle,
Eastern
regions
Chinese
universities.
It’s
noteworthy
that
respondents
were
freshmen.
Our
findings
indicate
freshmen
more
susceptible
experiencing
IA.
Approximately
75%
engaged
leisure
revealing
an
inverse
correlation
between
activity
This
aligns
with
level
involvement,
emphasizing
potential
benefits
mitigating
did
not
uncover
any
geographic
location
occurrence
IA,
nor
it
find
differences
medical
non-medical
Furthermore,
revealed
no
variations
different
ethnic
backgrounds.
underlying
mechanism
is
being
currently
determined.
data
suggest
gender,
have
Language: Английский
Online peer support for mental health in individuals with post-acute sequelae of COVID-19: A pre-post pilot study with mixed methods
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 16, 2024
Abstract
Objective
This
pilot
examined
the
effect
of
online
peer
support
on
mental
health
problems
among
individuals
with
post-acute
sequelae
COVID-2019
(PASC).
Methods
A
single-arm
pre-post
design
consisting
eight
sessions
1
h
per
week
three
to
six
participants
and
two
facilitators
group
was
performed.
Participants
were
recruited
from
communities,
social
media,
medical
clinics
for
PASC
between
May
August
2023.
The
degrees
depression,
anxiety,
loneliness,
withdrawal,
self-esteem
measured
pre-
post-intervention.
Participants’
statements
during
analyzed
using
thematic
analyses.
Results
Of
18
participants,
3
dropped
out
interventions,
17
(including
2
who
out)
completed
post-intervention
questionnaires.
Depression
severity
significantly
decreased
in
paired
t-test
linear
mixed
model.
following
interactions
extracted:
conveying
same
feelings,
dealing
difficulties,
showing
empathy,
enhancing
atmosphere,
adapting
suit
conditions.
Impressions
extracted
participating
interventions
included
feelings
emotional
support,
a
sense
bonding,
changes
perspective,
behaviors
or
new
actions
through
participation,
inadequacy
sessions,
adverse
effects
associated
participation.
Conclusion
Online
may
be
helpful
treating
depression
PASC.
Language: Английский
Online peer support for mental health in individuals with post‐acute sequelae of COVID‐19: A pre‐post pilot study with mixed methods
Psychiatry and Clinical Neurosciences Reports,
Journal Year:
2024,
Volume and Issue:
3(3)
Published: Aug. 18, 2024
This
pilot
examined
the
effect
of
online
peer
support
on
mental
health
problems
among
individuals
with
post-acute
sequelae
COVID-2019
(PASC).
Language: Английский
Difference in the Risk of Discrimination on Psychological Distress Experienced by Early Wave Infected and Late Wave Infected COVID-19 Survivors
Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: June 15, 2023
Abstract
The
psychological
distress
experienced
by
coronavirus
disease
of
2019
(COVID-19)
survivors
after
recovery
from
the
illness
is
amplified
discrimination
endured
because
their
infection
status.
However,
difference
in
risk
facing
and
experiencing
early
late
waves
COVID-19
pandemic
remain
unclear.
This
study
aimed
to
investigate
whether
status
was
lower
or
on
more
serious
later,
rather
than
earlier
waves.
We
conducted
two
online
surveys
collect
data
divided
into
groups.
participants
with
scores
five
Kessler
Psychological
Distress
Scale
were
identified
as
having
distress.
based
if
they
had
being
blamed,
some
type
discrimination,
themselves
families
maligned.
timing
split
infected
during
for
2021
later
2022
participants.
Modified
Poisson
regression
analyses
performed
using
experiences
dependent
variables
independent
variables.
further
presence
a
variable
variables,
addition
interaction
effect
these
6,010
who
5,344
analyzed.
risks
forms
maligned
significantly
group
those
Experiences
highly
associated
waves,
while
only
blamed
showed
significant
association.
Risk
found
be
whereas
shown
Therefore,
we
submit
that
it
important
support
face
attempt
decrease
current
discriminatory
climate
caused
pandemic.
Language: Английский
Anxiety disorder and depression among people following recovery from COVID-19 in Hue city
Lan Nguyen Hoang,
No information about this author
Tan Trinh Ngoc,
No information about this author
Khoa Dang Cao
No information about this author
et al.
Journal of Medicine and Pharmacy,
Journal Year:
2023,
Volume and Issue:
unknown, P. 37 - 44
Published: Sept. 1, 2023
Objecives:
To
assess
anxiety
disorder
and
depression
among
people
following
recovery
from
COVID-19
in
Hue
city
to
identify
associated
factors.
Methods:
The
cross
sectional
descriptive
study
was
designed
on
400
persons
aged
18
years
above
who
were
confirmed
by
negative
PCR
test
directly
interviewed.
They
randomly
selected
4
wards
of
city.
Anxiety
assessed
with
GAD-7
(Generalized
Disorder)
scale
evaluated
PHQ-9
(Patient
Health
Questionnaire)
scale.
summed
score
10
higher
the
or
indicated
probable
depression.
Multivariate
logistic
regression
model
used
factors
affecting
Results:
10.5%
participants
had
13.5%
them
Factors
which
significantly
included
family
structure,
post-COVID-19
symptoms
death
their
relatives
due
COVID-19.
Conclusion:
Age,
presence
a
care
giver
when
participants.
Key
words:
disorder,
depression,
post-
COVID-19,
Language: Английский