Experiences of mpox illness and case management among cis and trans gay, bisexual and other men who have sex with men in England: a qualitative study

EClinicalMedicine, Journal Year: 2024, Volume and Issue: 70, P. 102522 - 102522

Published: March 12, 2024

BackgroundThe 2022–2024 global mpox outbreak, occurring primarily in the sexual networks of gay, bisexual and other men who have sex with (GBMSM), has not been accompanied by a focus on patient perspectives illness. We explore experiences GBMSM diagnosed England to understand needs for social clinical support.MethodsIn-depth interviews (March/July 2023) were conducted 22 2022, randomly selected from national surveillance database, 4 stakeholders clinical/community-based organisations. Interviews covered illness, testing, diagnosis, treatment contact tracing, recorded, transcribed analysed thematic framework.FindingsMedia coverage drawing homophobic stereotypes around between contributed feelings stigma shame. living HIV appeared cope better stigma, their being resilience. Younger less experience stigmatising illness found diagnosis more traumatic sometimes required support beyond what was provided. Accessing testing could be complicated when healthcare professionals did recognise symptoms. Men felt information course isolation vaccination after recovery often inconsistent contradictory. described that care health infectious disease units usually met emotional medical needs. This frequently linked these services having skills working community managing infection risk sensitively. General hospital centralised tracing increase as some staff perceived lack supporting and, sometimes, knowledge. Long-term impacts included mental challenges, urethral/rectal symptoms life-changing disability.InterpretationIn this study central feature among exacerbated or lessened depending Involving communities affected outbreaks co-producing, planning delivering (including contact-tracing) may help improve provided.FundingTCW, AJR, AS FMB received National Institute Health Care Research (NIHR) under its Programme Grants Applied (Ref: NIHR202038). CS JS receive Protection Unit (NIHR HPRU) Blood Borne Sexually Transmitted Infections at UCL partnership UKHSA; RV receives NIHR HPRU Emerging Zoonotic Gastrointestinal Infections. The views expressed are those author(s) necessarily NIHR, UK Security Agency, World Organization Department Social Care.

Language: Английский

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“It’s another gay disease”: an intersectional qualitative approach contextualizing the lived experiences of young gay, bisexual, and other sexual minoritized men in the United States during the mpox outbreak

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: June 11, 2024

The U.S. mpox outbreak in 2022 introduced new and exacerbated existing challenges that disproportionately stigmatize gay, bisexual, other sexual minoritized men (GBSMM). This study contextualizes the perceptions, susceptibility, lived experiences of among GBSMM using an intersectional framework.

Language: Английский

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Prevention of sexual transmission of mpox: a systematic review and qualitative evidence synthesis of approaches

Infectious Diseases, Journal Year: 2024, Volume and Issue: 56(8), P. 589 - 605

Published: July 3, 2024

The ongoing multi-country mpox outbreak in previously unaffected countries is primarily affecting sexual networks of men who have sex with men. Evidence needed on the effectiveness recommended preventive interventions. To inform WHO guidelines, a systematic review and qualitative evidence synthesis were conducted behavioural interventions to reduce: (i) acquisition; (ii) onward transmission from confirmed/probable cases; (iii) utility asymptomatic testing.

Language: Английский

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The Agile Co-production and Evaluation framework for developing public health interventions, messaging and guidance

Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 11

Published: June 26, 2023

A lesson identified from the COVID-19 pandemic is that we need to extend existing best practice for intervention development. In particular, integrate (a) state-of-the-art methods of rapidly coproducing public health interventions and messaging support all population groups protect themselves their communities with (b) evaluating co-produced determine which are acceptable effective. This paper describes Agile Co-production Evaluation (ACE) framework, intended provide a focus investigating new ways developing effective by combining co-production large-scale testing and/or real-world evaluation. We briefly review some participatory, qualitative quantitative could potentially be combined propose research agenda further develop, refine validate packages in variety contexts combinations feasible, cost-effective achieve goal improving reducing inequalities.

Language: Английский

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Receptiveness to monkeypox vaccines and public health communication strategies among gay, bisexual and other men who have sex with men in Singapore: cross-sectional quantitative and qualitative insights

Sexually Transmitted Infections, Journal Year: 2024, Volume and Issue: 100(6), P. 362 - 367

Published: May 31, 2024

Monkeypox (mpox) was declared as a global health emergency by the WHO, with most reported cases disproportionately involving gay, bisexual and other men who have sex (GBMSM). This study explored willingness of Singaporean GBMSM to receive mpox vaccines engage in changes sexual behaviour, analysed factors influencing both decisions.

Language: Английский

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Monkeypox-related knowledge and vaccination willingness among HIV-diagnosed and -suspected males: a cross-sectional survey in Changsha

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 7, 2025

This study aimed to update baseline data on monkeypox (mpox)-related knowledge and vaccination willingness among human immunodeficiency virus (HIV) diagnosed suspected males. The cross-sectional survey was conducted in Changsha, a provincial capital China, during 5 JULY SEPTEMBER 2023. Among the three groups, participants "previously diagnosed" group were recruited from cohort of HIV-infected patients. "newly "suspected" groups outpatients grouped according their confirmatory test results. exploratory factor analysis firstly applied capture latent structure participants' response questionnaire about monkeypox. component scores compared between using Kruskal-Wallis H tests. chi-square then used assess difference mpox MSM non-MSM each group. Finally, multivariate logistic regression performed identify determinants willingness. A total 481 males included final analysis. results revealed that there gap participant groups. rate above 90%, while HIV-suspected 72.60%. Multivariate previously (adjusted odds ratio [aOR] = 0.314, 95% confidence interval [CI]: 0.105-0.940) (aOR 0.111, CI: 0.034-0.363) had lower level they referred newly Participants age ranging 25-34 0.287, 0.086-0.959) 35-44 0.136, 0.039-0.478) years showed willingness, 15-24 year better associated with higher 1.701, 1.165-2.483). Additionally, considerable percentage heterosexual individuals indicated acceptance vaccines. An overall high observed and-suspected male disparities noted those different HIV infection status, levels monkeypox, age. Addressing existing engaging people persistent risks-regardless sexual orientation-for timely diagnosis may facilitate vaccine-based mitigation measures against

Language: Английский

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“If that would have lessened my symptoms, that would have been great...”: a qualitative study about the acceptability of tecovirimat as treatment for mpox

BMC Medicine, Journal Year: 2025, Volume and Issue: 23(1)

Published: Jan. 21, 2025

Tecovirimat, an antiviral treatment for smallpox, was approved as a mpox by the European Medicines Agency in January 2022. Approval granted under "exceptional circumstances" based on effectiveness found pre-clinical challenge studies animals and safety humans showing minimal side effects. As clinical efficacy are still ongoing, there is currently limited information with regard to acceptability of tecovirimat treat mpox. The aim this study understand prospective use A co-produced, qualitative, focus group design conducted theoretically informed sample people from communities at higher risk experience illness. Thirteen participants took part: all self-identified cisgender male, 1 Black British, British Asian, 5 White, 3 White Other. Inclusion criteria were follows: illness; age 18 over; living United Kingdom (UK); UK during 2022 outbreak. Focus groups recorded, transcribed thematically analysed using combination inductive deductive coding Treatment Acceptability Framework. Very few aware option none offered it their Key factors influencing levels trust medicine; level information; provider communication approach; quality care. Marginalised highest may have prior structural discrimination which can greatly influence acceptability. This exploratory suggest that offering (or comparable emergency-licensed treatments) acceptable, although uptake will depend knowledge options, medicine medical professionals provision relevant choice. To increase such treatments, clinicians should ensure patients symptom management including pain relief; acknowledge address patient concerns upfront within context non-stigmatising care; communicate offers consistent supportive manner line locally eligibility protocols time.

Language: Английский

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Psychosocial impact and stigma on men who have sex with men due to monkeypox

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 19, 2025

The recent Monkeypox (Mpox) outbreak has disproportionately affected men who have sex with (MSM), amplifying stigma and discrimination. While prior research examined media portrayals public perceptions, little is known about MSM's direct experiences. To address this gap, we assess discrimination, stigma, psychosocial impact across social healthcare settings. A cross-sectional observational study was conducted using a structured, pilot-tested survey to discrimination against MSM in media, family, socio-occupational, environments. Among 115 surveyed, 81.7% observed discriminatory comments while noted workplaces (41.7%), by family/friends (45.2%), cohabitants (15.7%), (34.8%). Stigma significantly impacted healthcare-seeking behavior, 33% avoiding medical care due fear of Psychologically, 50.4% reported low mood/anxiety, 72.7% those frequently fearing Mpox also experienced these symptoms. led 71.3% alter sexual primarily reducing encounters (60%). Fear strongly associated behavioral changes (p < 0.001). exacerbated toward MSM, highlighting an urgent need for intervention. Authorities, community leaders must disseminate accurate information implement psychological support programs mitigate its detrimental effects on MSM.

Language: Английский

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Acceptability of public health information and prevention measures by gay men, bisexual men and men who have sex with men during the French Mpox outbreak in 2022: the ANRS-MPX-SHS cross-sectional survey

Sexually Transmitted Infections, Journal Year: 2025, Volume and Issue: unknown, P. sextrans - 056406

Published: April 18, 2025

Objectives This study investigated the acceptability by gay men, bisexual men and other who have sex with (GBMSM) of French public health information prevention measures implemented during 2022 Mpox outbreak. Methods ANRS-MPX-SHS "Mpox: perception risks, vaccination" is a cross-sectional survey conducted in GBMSM between July September 2022. Online questionnaires collected about Mpox-related awareness, perceptions behaviours. Multiple correspondence analysis identified participant profiles according to their level The outcome was variable grouping participants into three profiles: ‘strong endorsers’, ‘uninformed hesitant endorsers’ ‘indifferent objectors’. Multinomial logistic regression used estimate factors associated each profile. Results Of 5688 participants, 5320 (93.5%) had available data for outcome. latter were mostly cisgender (98%), aged 35 54 years (54.5%), tertiary education (82%); 44% living Greater Paris region. Strong endorsers, uninformed endorsers indifferent objectors accounted 77.8%, 14.4% 7.8% sample, respectively. Participants education, those exclusively taking pre-exposure prophylaxis (ie, HIV-negative participants), HIV-positive individuals region, all less likely be or objectors. no lifetime HIV/sexually transmitted infection (STI) screening infrequent were, respectively, more belong these two profiles. Conclusions Participants’ outbreak France depended on perceived capability authorities effectively diversify targets, representations communication channels. In order prevent transmission (and STIs) general population future outbreaks, adopted must take account needs, experiences persons never not regularly screened HIV/STIs.

Language: Английский

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A theory-based assessment of mpox: Findings from a nationally representative survey of U.S. adults

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(3), P. e0299599 - e0299599

Published: March 15, 2024

The purpose of this research was to examine individual differences related fear of, perceived susceptibility to, and severity mpox as well knowledge, fear, susceptibility, predictors vaccine intention in a national survey U.S. adults (aged ≥18 years). Address-based sampling (ABS) methods were used ensure full coverage all households the nation, reflecting 2021 March Supplement Current Population Survey. Internet-based surveys self-administered by Ipsos between September 16–26, 2022. N = 1018 participants completed survey. included items, based partially on Health Belief Model, assessing (1 item; responses from 1 [Definitely not] 5 [Definitely]), (7-item scale; α .89; theoretical mean 7–35), (3-item .85; 3–15), (4-item .65; 4–20). Higher scores indicate greater severity. One-way ANOVAs run score demographic groups (e.g., gender, race/ethnicity, sexual orientation), multiple regression analyses assessed relationship (mpox susceptibility/severity, fear) single outcome (vaccination intention), while controlling for covariates. Sampling weights applied analyses. Only 1.8% (n 18) respondents reported having received vaccine. While low (M 2.09, SD 0.99), overall racial/ethnic, orientation, education, household income statistically significant. Fear very 13.13, 5.33), there significant both among groups. not feeling susceptible 5.77, 2.50), they generally rated just above terms 11.01, 2.85). Mpox severity, vaccinate, with representing strongest predictor. Overall, Americans’ vaccination mpox/vaccine intent low. Gay/lesbian racial/ethnic minority felt more viewed severely, compared heterosexual White respondents, respectively. These data may be tailor risk prevention vaccination) interventions, cases continue surge current global outbreak. Greater perceptions about exist largely populations. public health messaging promote can focus improving addressing mpox, such messages should carefully crafted prevent disproportionate negative effects marginalized communities.

Language: Английский

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