PubMed,
Journal Year:
2024,
Volume and Issue:
5(4), P. 372 - 389
Published: Jan. 1, 2024
The
convergence
of
organoid
technology
and
artificial
intelligence
(AI)
is
poised
to
revolutionise
oral
healthcare.
Organoids
-
three-dimensional
structures
derived
from
human
tissues
offer
invaluable
insights
into
the
complex
biology
diseases,
allowing
researchers
effectively
study
disease
mechanisms
test
therapeutic
interventions
in
environments
that
closely
mimic
vivo
conditions.
In
this
review,
we
first
present
historical
development
organoids
delve
current
types
organoids,
focusing
on
their
use
models,
regeneration
microbiome
intervention.
We
then
compare
single-source
multi-lineage
assess
latest
progress
bioprinted,
vascularised
neural-integrated
organoids.
next
part
highlight
significant
advancements
AI,
emphasising
how
AI
algorithms
may
potentially
promote
for
early
detection
diagnosis,
personalised
treatment,
prediction
drug
screening.
However,
our
main
finding
identification
remaining
challenges,
such
as
data
integration
critical
need
rigorous
validation
ensure
clinical
reliability.
Our
viewpoint
AI-enabled
are
still
limited
applications
but,
look
future,
potential
transformation
AI-integrated
microbial
interactions
discoveries.
By
synthesising
these
components,
review
aims
provide
a
comprehensive
perspective
state
future
implications
role
advancing
healthcare
improving
patient
outcomes.
Diagnostics,
Journal Year:
2025,
Volume and Issue:
15(3), P. 280 - 280
Published: Jan. 24, 2025
Background/Objectives:
Oral
cancer,
the
sixth
most
common
cancer
worldwide,
is
linked
to
smoke,
alcohol,
and
HPV.
This
scoping
analysis
summarized
early-onset
oral
diagnosis
applications
address
a
gap.
Methods:
A
review
identified,
selected,
synthesized
AI-based
diagnosis,
screening,
prognosis
literature.
The
verified
study
quality
relevance
using
frameworks
inclusion
criteria.
full
search
included
keywords,
MeSH
phrases,
Pubmed.
AI
were
tested
through
data
extraction
synthesis.
Results:
outperforms
traditional
analysis,
prediction
approaches.
Medical
pictures
can
be
used
diagnose
with
convolutional
neural
networks.
Smartphone
AI-enabled
telemedicine
make
screening
affordable
accessible
in
resource-constrained
areas.
methods
predict
risk
patient
data.
also
arrange
treatment
histopathology
images
heterogeneity,
restricted
longitudinal
research,
clinical
practice
inclusion,
ethical
legal
difficulties.
Future
potential
includes
uniform
standards,
long-term
investigations,
regulatory
frameworks,
healthcare
professional
training.
Conclusions:
may
transform
treatment.
It
develop
early
detection,
modelling,
imaging
phenotypic
change,
prognosis.
approaches
should
standardized,
longitudinally,
practical
issues
related
real-world
deployment
addressed.
Dentomaxillofacial Radiology,
Journal Year:
2024,
Volume and Issue:
53(7), P. 439 - 446
Published: June 27, 2024
To
develop
and
validate
a
modified
deep
learning
(DL)
model
based
on
nnU-Net
for
classifying
segmenting
five-class
jaw
lesions
using
cone-beam
CT
(CBCT).
Biomolecules,
Journal Year:
2024,
Volume and Issue:
14(7), P. 787 - 787
Published: July 1, 2024
Oral
health
has
witnessed
a
significant
transformation
with
the
integration
of
biomarkers
in
early-diagnostic
processes.
This
article
briefly
reviews
types
used
screening
and
early
detection
oral
diseases,
particularly
cancer,
periodontal
dental
caries,
an
emphasis
on
molecular
biomarkers.
While
advent
these
may
represent
leap
forward
healthcare,
it
also
opens
door
to
potential
overtesting,
overdiagnosis,
overtreatment.
To
inform
selection
novel
ensure
their
rational
use
tests,
is
imperative
consider
some
key
characteristics,
which
are
specific
biomarker
(e.g.,
surrogate
should
reliably
reflect
primary
outcome),
test
sensitivity
specificity
must
be
balanced
based
disease
interest),
efficacy
treatment
improve
when
condition
diagnosed
earlier).
For
systemic
conditions
associated
researchers
extremely
cautious
determining
who
“at
risk”,
such
risk
small,
non-existent,
or
inconsequent.
framework
aims
that
advancements
diagnostics
translate
into
genuine
improvements
patient
care
well-being.
World Journal of Methodology,
Journal Year:
2025,
Volume and Issue:
15(3)
Published: March 6, 2025
This
analytical
research
paper
explores
the
transformative
impact
of
artificial
intelligence
(AI)
in
orthodontics,
with
a
focus
on
its
objectives:
Identifying
current
applications,
evaluating
benefits,
addressing
challenges,
and
projecting
future
developments.
AI,
subset
computer
science
designed
to
simulate
human
intelligence,
has
seen
rapid
integration
into
orthodontic
practice.
The
examines
AI
technologies
such
as
machine
learning,
deep
natural
language
processing,
vision,
robotics,
which
are
increasingly
used
analyze
patient
data,
assist
diagnosis
treatment
planning,
automate
routine
tasks,
improve
communication.
systems
offer
precise
malocclusion
diagnoses,
predict
outcomes,
customize
plans
by
leveraging
dental
imagery.
They
also
streamline
image
analysis,
diagnostic
accuracy,
enhance
engagement
through
personalized
objectives
include
benefits
terms
efficiency,
care,
while
acknowledging
challenges
like
data
quality,
algorithm
transparency,
practical
implementation.
Despite
these
hurdles,
presents
promising
prospects
advanced
imaging,
predictive
analytics,
clinical
decision-making.
In
conclusion,
holds
potential
revolutionize
practices
improving
operational
precision
outcomes.
With
collaborative
efforts
overcome
could
play
pivotal
role
advancing
care.
BMC Oral Health,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: April 15, 2025
Artificial
intelligence
(AI)
has
rapidly
advanced
in
healthcare
and
dental
education,
significantly
impacting
diagnostic
processes,
treatment
planning,
academic
training.
The
aim
of
this
study
is
to
evaluate
the
performance
differences
between
different
large
language
models
(LLMs)
by
analyzing
their
accuracy
rates
answers
multiple
choice
oral
pathology
questions.
This
evaluates
eight
LLMs
(Gemini
1.5,
Gemini
2,
ChatGPT
4o,
4,
o1,
Copilot,
Claude
3.5,
Deepseek)
answering
multiple-choice
questions
from
Turkish
Dental
Specialization
Examination
(DUS).
A
total
100
2012
2021
were
analyzed.
Questions
classified
as
"case-based"
or
"knowledge-based".
responses
"correct"
"incorrect"
based
on
official
answer
keys.
To
prevent
learning
biases,
no
follow-up
feedback
provided
after
LLMs'
responses.
Significant
observed
among
(p
<
0.001).
o1
achieved
highest
(96
correct,
4
incorrect),
followed
(84
correct),
2
Deepseek
(82
correct
each).
Copilot
had
lowest
(61
correct).
Case-based
showed
notable
variations
=
0.034),
where
excelled.
For
knowledge-based
questions,
demonstrated
Post-hoc
analysis
revealed
that
performed
better
than
most
other
across
both
case-based
0.0031).
variable
proficiency
with
showing
higher
accuracy.
shows
promise
a
supplementary
educational
tool,
though
further
validation
required.